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Temporal variations of CO_2 concentration near land surface and its response to meteorological variables in Heihe River Basin, northwest China

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Journal of Environmental Sciences 2006年第4期18卷 708-715页

作者： CHEN Ren-sheng KANG Er-si JI Xi-bin yang Jian-ping ZHANG zhi-hui yang Yong Laboratory of Watershed Hydrology and Ecology Cold and Arid Regions Environmental and Engineering Research Institute Chinese Academy ofSciences Lanzhou 730000 China

Atmospheric CO2 concentration （CC） near land surface and meteorological variables have been measured at four sites, named Yeniugou （alpine meadow and permafrost）, Xishui （mountainous forest）, Linze （oasis edge） and Ejina （lower desert）, respectively, in Heihe River Basin, northwest China. The results showed that, the half hourly CC at night was larger than in daytime, and the daily averaged CC was the largest in winter. The averaged CC of 932 d at the Linze was about 418 ppm, was about 366 ppm in the 762 d at the Ejina. In the same period from September 23 to November 9, 2004, the averaged CC was about 625,334, 436 and 353 ppm, at Yeniugou, Xishui, Linze and Ejina, respectively. The linear relationship between daily averaged CC and air temperature T was negative, between CC and relative humidity （RH） was positive. The linear CC-atmospheric pressure （A P） relationship was negative at the Linze and Yeniugou, was positive at the Ejina. The relationship between CC and global radiation R was exponent, and soil temperature Ts was negative linear, and soil water content was complex. The correlation between CC and wind speed was not existent. Using meteorological variables together to simulate CC, could give good results.

关键词： CO2 concentration meteorological variables Heihe River Basin

Effects of aspirin and enoxaparin in a rat model of liver fibrosis

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World Journal of Gastroenterology 2017年第35期23卷 6412-6419页

作者： Chen-Jie Li zhi-hui yang Xiao-Liu Shi De-Liang Liu Department of Gastroenterology Second Xiangya Hospital of Central South University Department of Medicine Hospital of National University of Defense Technology

AIM To examine the effects of aspirin and enoxaparin on liver function, coagulation index and histopathology in a rat model of liver *** Forty-five male Sprague-Dawley rats were randomly divided into the control group(n = 5) and model group(n = 40). Thioacetamide(TAA) was used to induce liver fibrosis in the model group. TAA-induced fibrotic rats received TAA continuously(n = 9), TAA + low-dose aspirin(n = 9), TAA + high-dose aspirin(n = 9) or TAA + enoxaparin(n = 9) for 4 wk. All rats were euthanized after 4 wk, and both hematoxylin-eosin and Masson staining were performed to observe pathological changes in liver tissue. RESULTS Liver fibrosis was assessed according to the METAVIR score. Compared with untreated cirrhotic controls, a significant improvement in fibrosis grade was observed in the low-dose aspirin, high-dose aspirin and enoxaparin treated groups, especially in the high-dose aspirin treated group. Alanine aminotransferase and total bilirubin were higher, albumin was lower and both prothrombin time and international normalized ratio were prolonged in the four treatment groups compared to controls. No significant differences among the four groups were *** Aspirin and enoxaparin can alleviate liver fibrosis in this rat model.

关键词： Aspirin Enoxaparin Thioacetamide Liver fibrosis Rat

Anefficient parallel and distributed solution to nonconvex penalized linear SVMs

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Frontiers of Information Technology & Electronic Engineering 2020年第4期21卷 587-603页

作者： Lei GUAN Tao SUN Lin-bo QIAO zhi-hui yang Dong-sheng LI Ke-shi GE Xi-cheng LU College of Computer National University of Defense TechnologyChangsha 410073China School of Computer Science Fudan UniversityShanghai 201203China Shanghai Key Laboratory of Data Science Shanghai 201203China

Support vector machines(SVMs)have been recognized as a powerful tool to perform linear *** combined with the sparsity-inducing nonconvex penalty,SVMs can perform classification and variable selection ***,the nonconvex penalized SVMs in general cannot be solved globally and efficiently due to their nondifferentiability,nonconvexity,and *** solutions to the nonconvex penalized SVMs typically solve this problem in a serial fashion,which are unable to fully use the parallel computing power of modern multi-core *** the other hand,the fact that many real-world data are stored in a distributed manner urgently calls for a parallel and distributed solution to the nonconvex penalized *** circumvent this challenge,we propose an efficient alternating direction method of multipliers(ADMM)based algorithm that solves the nonconvex penalized SVMs in a parallel and distributed *** design many useful techniques to decrease the computation and synchronization cost of the proposed parallel *** time complexity analysis demonstrates the low time complexity of the proposed parallel ***,the convergence of the parallel algorithm is *** evaluations on four LIBSVM benchmark datasets demonstrate the efficiency of the proposed parallel algorithm.

关键词： Linear classification Support vector machine(SVM) Nonconvex penalty Alternating direction method of multipliers(ADMM) Parallel algorithm

Photo-Responsive Carbon Capture over Metalloporphyrin-C_(60) Metal-Organic Frameworks via Charge-Transfer

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Research 2024年第3期2023卷 233-241页

作者： Shi-Chao Qi Zhen Sun zhi-hui yang Yun-Jie Zhao Jia-Xin Li Xiao-Qin Liu Lin-Bing Sun State Key Laboratory of Materials-Oriented Chemical Engineering Jiangsu National Synergetic Innovation Center for Advanced Materials(SICAM)College of Chemical EngineeringNanjing Tech UniversityNanjing 211816China.

Great efforts have been devoted to the study of photo-responsive adsorption,but its current methodology largely depends on the well-defined photochromic units and their photo-driven molecular ***,a methodology to fabricate nondeforming photo-responsive sorbents is successfully *** C_(60)-fullerene doping in metalloporphyrin metal-organic frameworks(PCN-M,M=Fe,Co,or Ni)and intensively interacting with the metalloporphyrin sites,effective charge-transfer can be achieved over the metalloporphyrin-C_(60) architectures once excited by the light at 350 to 780 *** electron density distribution and the resultant adsorption activity are thus changed by excited states,which are also stable enough to meet the timescale of microscopic adsorption *** charge-transfer over Co(II)-porphyrin-C_(60) is proved to be more efficient than the Fe(II)-and Ni(II)-porphyrin-C_(60) sites,as well as than all the metalloporphyrin sites,so the CO_(2) adsorption capacity(CAC;at 0°C and 1 bar)over the C_(60)-doped PCN-Co can be largely improved from 2.05 mmol g^(−1) in the darkness to 2.69 mmol g−1 with light,increased by 31%,in contrast to photo-irresponsive CAC over all C_(60)-undoped PCN-M sorbents and only the photo-loss CAC over C_(60).

关键词： porphyrin adsorption excited

Inhibition of the Hedgehog Signaling Pathway Depresses the Cigarette Smoke-Induced Malignant Transformation of 16HBE Cells on a Microfluidic Chip

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Chinese Medical Journal 2018年第10期131卷 1191-1198页

作者： Yong-Xin Qin zhi-hui yang Xiao-hui DU hui Zhao Yuan-Bin Liu Zhe Guo Qi Wang Department of Respiratory Medicine The Second Affiliated Hospital Dalian Medical University Dalian Liaoning 116027 China Department of Critical Care Medicine The First Affiliated Hospital Dalian Medical University Dalian Liaoning 116021 China Department of Scientific Research Center The Second Affiliated Hospital Dalian Medical University Dalian Liaoning 116027 China

Background：The hedgehog signaling system （HHS） plays an important role in the regulation of cell proliferation and differentiation during the embryonic ***,little is known about the involvement of HHS in the malignant transformation of *** study aimed to detect the role of HHS in the malignant transformation of human bronchial epithelial （16HBE） ***：In this study,two microfluidic chips were designed to investigate cigarette smoke extract （CSE）-induced malignant transformation of *** A contained a concentration gradient generator,while chip B had four cell chambers with a central *** 16HBE cells cultured in chip A were used to determine the optimal concentration of CSE for inducing malignant *** 16HBE cells in chip B were cultured with 12.25% CSE （Group A）,12.25% CSE ± 5 μmol/L cyclopamine （Group B）,or normal complete medium as control for 8 months （Group C）,to establish the in vitro lung inflammatory-cancer transformation *** transformed cells were inoculated into 20 nude mice as cells alone （Group 1） or cells with cyclopamine （Group 2） for tumorigenesis *** of HHS proteins was detected by Western *** were expressed as mean ± standard *** t-test was used for paired samples,and the difference among groups was analyzed using a one-way analysis of ***：The optimal concentration of CSE was 12.25%.Expression of HHS proteins increased during the process of malignant transformation （Group B *** A,F =7.65,P 〈 0.05）.After CSE exposure for 8 months,there were significant changes in cellular morphology,which allowed the transformed cells to grow into tumors in 40 days after being inoculated into nude *** could effectively depress the expression of HHS proteins （Group C *** B,F =6.47,P 〈 0.05） and prevent tumor growth in nude mice （Group 2 *** 1,t=31.59,P〈 0.01）.Conclusions：The activity of HHS is upregulated during the CSE-induced malignant tran

关键词： Hedgehog Signaling System Lung Cancer Malignant Transformation Microfluidic Chip

Optimal Microwave Radiation Field Parameters for Mercury Ion Microwave Frequency Standards

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Chinese Physics Letters 2016年第6期33卷 21-24页

作者： zhi-hui yang Hao Liu Yue- Hong He Man Wang Yong-Quan Wan Yi-He Chen Lei She Jiao-Mei Li Key Laboratory of Atomic Frequency Standard Chinese Academy of Sciences Wuhan Institute of Physics and Mathematics Chinese Academy of Sciences University of Chinese Academy of Sciences

We propose a method to determine the optimal power of the microwave resonance transition that simultaneously improves the signal-to-noise ratio and reduces line width based on saturation broadening theory and experiment. Saturation broadening spectra of the ground state hyperfine transition of trapped 199Hg＋ ions are measured and analyzed. The value of the optimal microwave power is obtained by using the proposed method and is verified. Rabi oscillations decay spectra of trapped 199Hg＋ ions are observed and the optimal microwave irradiation time for the maximum transition signal intensity is determined. This work will help to improve the short-term frequency stability of the mercury ion microwave frequency standard.

关键词： of on it Optimal Microwave Radiation Field Parameters for Mercury Ion Microwave Frequency Standards dBm is for

Physiological characteristics of Ficus tikoua under antimony stress

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Transactions of Nonferrous Metals Society of China 2017年第4期27卷 939-945页

作者： Li-yuan CHAI Yong WANG zhi-hui yang School of Metallurgy and Environment Central South University Changsha 410083 China Chinese National Engineering Research Center for Control and Treatment of Heavy Metal Pollution Central South University Changsha 410083 China

A greenhouse culture experiment was used to evaluate the effects of antimony(Sb)stress on Ficus tikoua(***).Theresults showed that the growth of *** leaves was significantly inhibited when Sb concentration was higher than30μmol/L,andno significantly inhibitory effect of Sb on the roots and stems of *** was found in all the treatments,implying that leaves weremore sensitive to Sb toxicity than roots and *** concentration in the roots was higher than that in the stems and *** reduce reactive oxygen species(ROS)level in the ***,the activities of superoxide dismutase(SOD),peroxidase(POD)andcatalase(CAT)increased with Sb treatments,but the SOD and CAT were more early active than *** the decrease ofchlorophyll content with high Sb treatments(450μmol/L)was observed at the end of the experiments,the positive impact onchlorophyll content was observed with all the Sb treatments at the early *** significant difference of the maximum quantumefficiency of PSII and quantum yield of PSII electron transport values with different Sb treatments was observed at the end of thisexperiment,suggesting that the photosynthesis was not inhibited with Sb concentration below450μmol/*** results implied acertain tolerance to Sb stress for *** meets the essential condition for utilization in Sb contamination environments.

关键词： antimony biomass antioxidant enzyme activity F. tikoua chlorophyll fluorescence

Effects of organic acids on heavy metal release or immobilization in contaminated soil

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Transactions of Nonferrous Metals Society of China 2022年第4期32卷 1277-1289页

作者： Wen-bin YAO Lei HUANG zhi-hui yang Fei-ping ZHAO School of Metallurgy and Environment Central South UniversityChangsha 410083China Chinese National Engineering Research Center for Control and Treatment of Heavy Metal Pollution Changsha 410083China Guangzhou University-Linköping University Research Center on Urban Sustainable Development Guangzhou UniversityGuangzhou 510006China

In order to explicit the environmental activity of heavy metals affected by different organic acids in soil,a batch incubation experiment was explored to investigate the influence of high relative molecular mass organic acid(HMWOA)(humic acid and fulvic acid)and low relative molecular mass organic acid(LMWOA)(threonic acid and oxalic acid)on the release or immobilization of Pb,Cu and Cd in *** showed that LMWOA,especially threonic acid,had a good performance in the release of Pb,Cu and Cd from soils,and decrease in the fractions of HOAc-extractable,reducible and oxidable Pb,Cu and ***,HMWOA,especially humic acid,decreased the release of Pb,Cu and Cd,while it increased the fractions of HOAc-extractable,reducible and oxidable Pb,Cu and Cd,indicating that HMWOA can immobilize heavy *** release of Pb,Cu and Cd caused by LMWOA was attributed to the dissociation of soil organic matter and amorphous iron oxides since the total organic carbon and the water-soluble iron *** immobilization of Pb,Cu and Cd by HMWOA was attributed to the adsorption onto HMWOA followed by amorphous iron since HMWOA resulted in a significant decrease of zeta potential and an increase of amorphous iron *** can be concluded that LMWOA has a potential application in soil washing remediation,while HMWOA can be used in the immobilization remediation for heavy metals contaminated soils.

关键词： low relative molecular mass organic acid humic acid fulvic acid soil remediation fractionation transformation of heavy metals

Pretreatment neutrophil-to-lymphocyte and platelet-to- lymphocyte ratios do not predict survival in patients with cervical cancer treated with neoadjuvant chemotherapy and radical hysterectomy

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Chinese Medical Journal 2013年第8期126卷 1464-1468页

作者： WANG Dan WU Ming FENG Feng-zhi HUANG hui-fang yang Jia-xin SHEN Keng XIANG yang Department of Obstetrics and Gynecology Peking Union McdicalCotlege Hospital Peking Union Medical College and ChineseAcademy of Medical Sciences Beijing 100730 China

Background A few inflammatory markers were studied to evaluate their possible prognostic roles in various cancers. The neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio are hypothesized to reflect the systemic inflammation. The objective of the present study was to investigate whether or not the pretreatment neutrophil-to-lymphocyte ratio or platelet-to-lymphocyte ratio can predict the survival of patients with cervical cancer treated with neoadjuvant chemotherapy and radical hysterectomy. Methods We performed a retrospective study on cervical cancer patients （FIGO stage Ib2-11b） who had undergone neoadjuvant chemotherapy and radical hysterectomy at Peking Union Medical College Hospital between January 1999 and December 2010. Data on demographics, clinical prognostic markers and histopathology were collected and analyzed. Univariate and multivariate analyses for prognostic factors were performed. Results A total of 111 patients were identified. The median neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios were 2.4 and 142.2, respectively. Overall survival and progression-free survival were neither significantly different between patients with high and low neutrophil-to-lymphocyte ratio （P=0.149 and P=0.108） nor in high and low platelet-to-lymphocyte ratio （P=0.336 and P=0.510）. On multivariate analysis, lymph node status （P=O.O00 and P=-O.O07） and lymphovascular space involvement （P=0.001 and P=0.001） were independent prognostic factors of progression-free survival and overall survival. Conclusions Lymph node status and lymphovascular space involvement were found to be independent prognostic factors for patients with cervical cancer who underwent neoadjuvant chemotherapy and radical hysterectomy. The pretreatment neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios seemed not to predict the survival of patients with cervical cancer treated with neoadjuvant chemotherapy and radical hysterectomy.

关键词： cervical cancer, neoadjuvant chemotherapy radical hysterectomy neutrophil-to-lymphocvte ratio:plutclet-to-lymphcyte ratio