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Subsurface deformation mechanism and the interplay relationship between strength–ductility and fretting wear resistance during fretting of a high-strength titanium alloy

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Friction 2024年第10期12卷 2259-2280页

作者： Yanlin TONG Ke HUA Haoyang XIE Yue CAO Zhuobin HUANG zhenpeng liang Xiaolin LI Hongxing WU Haifeng WANG State Key Laboratory of Solidification Processing Center of Advanced Lubrication and Seal MaterialsNorthwestern Polytechnical UniversityXi’an 710072China

Fretting wear damage of high-strength titanium fasteners has caused a large number of disastrous ***,it is believed that both high strength and excellent ductility can reduce fretting wear ***,whether strength and ductility are contradictory or not and their appropriate matching strategy under the external applied normal stress(Fw)are still confusing ***,by analyzing the subsurface-microstructure deformation mechanism of several samples containing variousαprecipitate features,for the first time,we design strategies to improve fretting damage resistance under different matching relation between Fw and the tensile strength of materials(Rm).It is found that when Fw is greater than Rm or Fw is nearly equivalent to Rm,the deformation mechanism mainly manifests as serious grain fragmentation ofβandαGB *** deformation in large areas only reduces damage to a limited *** is crucial to improve the strength to resist cracking and wear,but it is of little significance to improve the ***,when Fw is far less than Rm,coordinated deformation ability reflected by ductility plays a more important *** deformation mechanism mainly manifests as localized deformation ofβandαGB constituents(kinking induced by twinning and spheroidizing).A unique composite structure of nano-grained/lamellar layer and localized deformation transition layer reduces fretting damage by five times compared with a single nanograined *** when the strength is great enough,improving the plasticity can reduce *** study can provide a principle for designing fretting damage resistant alloys.

关键词： fretting wear high-strength titanium alloy microstructures subsurface deformation

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太阳能空气源热泵耦合相变蓄热器供热系统模拟研究

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沈阳建筑大学学报（自然科学版） 2024年第4期40卷 714-722页

作者：尚少文梁振鹏钱浩沈阳建筑大学市政与环境工程学院辽宁沈阳110168 沈阳有色冶金设计研究院有限公司辽宁沈阳110055

目的为提高可再生能源利用率,研究太阳能空气源热泵耦合相变蓄热器供热系统实际性能,建立适合夏热冬冷地区民用住宅的节能供热系统。方法利用TRNSYS软件建立太阳能空气源热泵耦合相变蓄热器供热系统模型,并与太阳能空气源热泵供热系统... 详细信息

目的为提高可再生能源利用率,研究太阳能空气源热泵耦合相变蓄热器供热系统实际性能,建立适合夏热冬冷地区民用住宅的节能供热系统。方法利用TRNSYS软件建立太阳能空气源热泵耦合相变蓄热器供热系统模型,并与太阳能空气源热泵供热系统进行对比分析,对两个系统从制热量、耗电量、能效比以及室内人体热舒适度四个方面进行模拟分析,使用PMV-PPD评价方法对两个系统的室内热舒适度进行评价。结果耦合相变蓄热器的供热系统耗电量低于无相变供热系统,节能率提高了13.29%;耦合相变蓄热器的供热系统平均能效比为3.5,太阳能空气源热泵供热系统的平均能效比为3.32,提高了5.14%;耦合供热系统可以为人体提供I级室内热环境水平的热舒适度,无相变供热系统只能为人体提供II级。结论太阳能空气源热泵耦合相变蓄热器供热系统节能性更好,系统能效更高,提高了可再生能源利用率,并且耦合供热系统在热舒适性方面优于无相变供热系统。

关键词： TRNSYS 空气源热泵相变储能热舒适

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循环酸化设备在硫酸制备工艺中的应用

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化工管理 2024年第16期 152-155页

作者：梁振鹏惠州市百利宏晟安化工有限公司广东惠州516000

在现代科学技术发展的背景下,硫酸制备工艺取得显著改进。文章基于此研究循环酸化设备在硫酸制备工艺中的应用,详细分析循环酸化设备的工作原理、结构特点及其在硫酸制备过程中的作用,发现该设备能够有效提高硫酸制备的效率和产量,同时... 详细信息

在现代科学技术发展的背景下,硫酸制备工艺取得显著改进。文章基于此研究循环酸化设备在硫酸制备工艺中的应用,详细分析循环酸化设备的工作原理、结构特点及其在硫酸制备过程中的作用,发现该设备能够有效提高硫酸制备的效率和产量,同时降低能耗和环境污染。文章探讨循环酸化设备在实际应用中存在的问题和优化方案,为其在硫酸制备领域的推广和应用提供理论和实践依据。

关键词：循环酸化设备硫酸制备工艺

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《俄罗斯联邦对外政策构想》与俄对外政策未来走向

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俄罗斯学刊 2024年第2期14卷 100-116页

作者：梁朕朋中国社会科学院俄罗斯东欧中亚研究所

2023年3月俄罗斯发布了普京自2012年入主克里姆林宫10多年来第三版《俄罗斯联邦对外政策构想》。三个版本的《构想》都强调发展与近邻关系,强调国家领土安全与主权安全。前两版《构想》将欧盟、美国视为优先发展的伙伴,2023年版《构想... 详细信息

2023年3月俄罗斯发布了普京自2012年入主克里姆林宫10多年来第三版《俄罗斯联邦对外政策构想》。三个版本的《构想》都强调发展与近邻关系,强调国家领土安全与主权安全。前两版《构想》将欧盟、美国视为优先发展的伙伴,2023年版《构想》将欧盟、美国视为侵害俄罗斯国家利益的主要国际力量,但俄罗斯仍然对美欧保持开放务实的合作态度。最新版《构想》中最重要的变化是俄罗斯希望借助亚太地区的多边行为体抗衡美西方,加速整合亚太主要力量,以确保欧亚地区的稳定。以往俄罗斯对外政策布局呈现的是稳中有进、通中有度的特点,以维护国家利益为基础,进攻和防御兼顾,在主要力量之间寻求平衡,实现国家利益最大化。预测未来,由乌克兰危机引发的美西方对俄罗斯持续加码的全方位、多领域制裁使俄罗斯目前无法就应对美西方的政策举措做出更多自我调节,只能暂时通过拉开距离的方式,等待找到修复关系的办法,同时保证国家利益不受侵害。

关键词：俄罗斯外交战略对外政策国家利益多极化世界秩序周边安全

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Structure and immunomodulatory activity of Lentinus edodes polysaccharides modified by probiotic fermentation

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Food Science and Human Wellness 2024年第1期13卷 421-433页

作者： Jingjing liang Meina Zhang Xiaohan Li Yuan Yue Xiaowei Wang Mengzhen Han Tianli Yue Zhouli Wang zhenpeng Gao College of Food Science and Engineering Northwest A&F UniversityYangling 712100China Xi'an GaoXin No.1 High School Xi'an 710065China

Plant-based fermentations provide an untapped source for novel biotechnological *** this study,a probiotic named Lactobacillus fermentum 21828 was introduced to ferment Lentinus *** were extracted from fermented and non-fermented *** and purified via DEAE-52 and Sephadex *** components designated F-LEP-2a and NF-LEP-2a were analyzed by FT-IR,HPGPC,HPAEC,SEM,GC-MS and *** results revealed that probiotic fermentation increased the molecular weight from 1.16×10^(4) Da to 1.87×10^(4) Da and altered the proportions of glucose,galactose and mannose,in which glucose increased from 45.94%to 48.16%.Methylation analysis and NMR spectra indicated that F-LEP-2a and NF-LEP-2a had similar linkage ***,their immunomodulatory activities were evaluated with immunosuppressive ***-LEP and F-LEP improved immune organ indices,immunoglobulin(Ig G and Ig M)and cytokines concentrations;restored the antioxidation capacity of liver;and maintained the balance of gut microbiota.F-LEP displayed better moderating effects on the spleen index,immunoglobulin,cytokines and the diversity of gut microbiota than NF-LEP(200,400 mg/kg).Our study provides an efficient and environment-friendly way for the structural modification of polysaccharides,which helps to enhance their biological activity and promote their wide application in food,medicine and other fields.

关键词： Lentinus edodes polysaccharide Lactobacillus fermentum fermentation Structural analysis Immunoregulatory activity Nuclear magnetic resonance

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In vivo evaluation of guide-free Cas9-induced safety risks in a pig model

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Signal Transduction and Targeted Therapy 2024年第8期9卷 3493-3506页

作者： Weikai Ge Shixue Gou Xiaozhu Zhao Qin Jin zhenpeng Zhuang Yu Zhao Yanhui liang Zhen Ouyang Xiaoyi Liul Fangbing Chen Hui Shi Haizhao Yan Han Wu liangxue Lai Kepin Wang China-New Zealand Joint Laboratory on Biomedicine and Health CAS Key Laboratory of Regenerative BiologyGuangdong Provincial Key Laboratory of Stem Cell and Regenerative MedicineJoint School of Life SciencesGuangzhou Institutes of Biomedicine and HealthChinese Academy of SciencesGuangzhou Medical UniversityGuangzhou 510530China Sanya institute of Swine resource Hainan Provincial Research Center of Laboratory AnimalsSanya 572000China Guangdong Provincial Key Laboratory of Large Animal models for Biomedicine Wuyi UniversityJiangmen 529020China Guangzhou National Laboratory Guangzhou 510005China SUniversity of Chinese Academy of Sciences 100049 BeijingChina Research Unit of Generation of Large Animal Disease Models Chinese Academy of Medical Sciences(2019RU015)Guangzhou 510530China

The CRISPR/Cas9 system has shown great potential for treating human genetic diseases through gene ***,there are concerns about the safety of this system,specifically related to the use of guide-free *** studies have shown that guidefree Cas9 can induce genomic instability in ***,the in vivo safety risks associated with guide-free Cas9 have not been evaluated,which is necessary for the development of gene therapy in clinical *** this study,we used doxycycline-inducible Cas9-expressing pigs to evaluate the safety risks of guide-free Cas9 in *** findings demonstrated that expression of guide-free Cas9 could induce genomic damages and transcriptome changes in *** severity of the genomic damages and transcriptome changes were correlate with the expression levels of Cas9 ***,prolonged expression of Cas9 in pigs led to abnormal phenotypes,including a significant decrease in body weight,which may be attributable to genomic damage-induced nutritional absorption and metabolic ***,we observed an increase in whole-genome and tumor driver gene mutations in pigs with long-term Cas9 expression,raising the risk of tumor *** in vivo evaluation of guide-free Cas9 in pigs highlights the necessity of considering and monitoring the detrimental effects of Cas9 alone as genome editing via the CRISPR/Cas9 system is implemented in clinical gene *** research emphasizes the importance of further study and implementation of safety measures to ensure the successful and safe application of the CRiSPR/Cas9 system in clinical practice.

关键词： CRISPR/Cas9 vivo alone

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Analysis and experimental study on resistance-increasing behavior of composite high efficiency autonomous inflow control device

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Petroleum Science 2024年第2期21卷 1290-1304页

作者： liang-liang Dong Yu-Lin Zhang School of Mechatronic Engineering Southwest Petroleum UniversityChengdu610500SichuanChina State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Southwest Petroleum UniversityChengdu610500SichuanChina Oil and Gas Equipment Technology Sharing and Service Platform of Sichuan ProvinceChengdu610500SichuanChina

Bottom water coning is the main reason to reduce the recovery of horizontal bottom water reservoir. By water coning, we mean the oil-water interface changes from a horizontal state to a mound-shaped cone and breaks through to the wellbore. Autonomous inflow control device(AICD) is an important instrument maintain normal production after bottom water coning, however, the resistance increasing ability of the swirl type AICD is insufficient at present, which seriously affects the water control effect. Aiming this problem, this paper designs a multi-stage resistance-increasing and composite type AICD. The separation mechanism of oil-water two phases in this structure, the resistance form of oil-water single phase and the resistance-increasing principle of water phase are analyzed. Establishing the dual-phase multi-stage separation and resistance-increasing model, and verified by measuring the throttling pressure drop and oil-water volume fraction of the AICD, it is found that the composite type AICD has the effect of ICD and AICD at the same time, which can balance the production rate of each well section at the initial stage of production, delay the occurrence of bottom water coning. In the middle and later stages of production, water-blocking can be effectively increased to achieve water control and stable *** structural sensitivity analysis, the influence law of various structural parameters on the water control performance of composite AICD was obtained. The simulation calculation results show that,compared with the existing swirl type AICD, composite AICD has higher sensitivity to moisture content,the water phase throttling pressure drop is increased by 4.5 times on average. The composite AICD is suitable for the entire stage of horizontal well production.

关键词： Water control Flow separation Flow resistance-increasing AICD device Simulation and experiment

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上合组织区域公共产品供求关系与成员国合作秩序的演变

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国家安全论坛 2023年第4期2卷 71-85,91-92页

作者：梁朕朋中国社会科学院俄罗斯东欧中亚研究所

上海合作组织运行二十多年来,成员国在安全与经济领域的合作秩序呈现出不同形态。其形态除了取决于成员国对上合组织区域安全公共产品与经济公共产品的供给需求、供给意愿与供给能力外,还受到上合组织权力结构与区域其他力量的影响。在... 详细信息

上海合作组织运行二十多年来,成员国在安全与经济领域的合作秩序呈现出不同形态。其形态除了取决于成员国对上合组织区域安全公共产品与经济公共产品的供给需求、供给意愿与供给能力外,还受到上合组织权力结构与区域其他力量的影响。在上合组织封闭状态下,成员国在安全与经济领域合作秩序的演化由成员国对上合组织区域公共产品的供求关系决定。均衡供求关系下合作秩序形态比较稳定,不均衡供求关系则使成员国合作秩序产生内生动力并向另一种合作秩序形态演化。区域内上合组织外部行为体与上合组织内成员国、上合组织区域安全、经济领域公共产品的竞合关系,会对上合组织成员国合作关系产生影响。扩员后的上合组织区域公共产品供给面临新机遇、新挑战,按照核心区域与核心领域进行合作调整,将使上合组织区域公共产品供给取得新成效。

关键词：上海合作组织区域公共产品供求关系合作秩序

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Global existence and large-time behavior for primitive equations with the free boundary

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Science China Mathematics 2024年第10期67卷 2303-2330页

作者： Hai-liang Li Chuangchuang liang School of Mathematical Sciences Capital Normal UniversityBeijing 100048China Academy for Multidisciplinary Studies Capital Normal UniversityBeijing 100048China College of Mathematics and Statistics Chongqing UniversityChongqing 401331China

In the present paper, the primitive equations, which can be used to simulate the large-scale motion of the ocean and atmosphere, are considered in the three-dimensional domain bounded below by a fixed solid boundary and above by a free-moving boundary. The global existence and uniqueness of strong solutions are established, and the long-time convergence to the equilibrium state is shown to be either at an exponential rate for the horizontal periodic domain or at an algebraic rate for the horizontal whole space.

关键词： primitive equations the free boundary value problem global well-posedness large-time behavior

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Sufficient Conditions for Amalgamated 3-Manifolds to be ∂-Irreducible

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Chinese Annals of Mathematics,Series B 2024年第2期45卷 161-172页

作者： Bing FANG Fengchun LEI liang liang School of Mathematical Sciences Dalian University of TechnologyDalian 116024LiaoningChina School of Mathematics Liaoning Normal UniversityDalian 116029LiaoningChina

In this paper,the authors give some sufficient conditions for an amalgamated 3-manifold along a compact connected surface F with boundary to be ∂-irreducible in terms of distances between some kinds of vertex subsets ... 详细信息

关键词： ∂-Irreducibility Irreducibility Amalgamated 3-manifold Curve complex Arc complex

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