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Science China Life Sciences 2025年第1期 297-299页

作者： Junbin Zhou Rongli Wei Guanghan Fan zhengxing Lian Xuanyu zhang Linsong Tang Zhetuo Qi Haiyang Xie Shusen zheng Qiang Wei Xiao Xu Department of Hepatobiliary and Pancreatic Surgery People's Hospital of LishuiAffiliated Lishui Hospital of Wenzhou Medical UniversityThe First Affiliated Hospital of Lishui University NHFPC Key Laboratory of Combined Multi-Organ Transplantation Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province Department of Hepatobiliary and Pancreatic SurgeryHangzhou First People's Hospital Department of Hepatobiliary and Pancreatic Surgery The First Affiliated HospitalZhejiang University School of Medicine Department of Urology The Second Affiliated HospitalZhejiang University School of Medicine Department of Hepatobiliary and Pancreatic Surgery Department of Liver TransplantationShulan (Hangzhou) Hospital Hangzhou Medical College Zhejiang University School of Medicine

Dear Editor, Liver transplantation(LT) is the only curative therapy for patients with endstage liver disease(He et al., 2023; Ling et al., 2022). Post-transplant hypertriglyceridemia(PTHT), which has an incidence of up to 32.8% in 6 months after LT, is one of the major post-transplant complications(Toshima et al., 2020).

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胡椒香气成分的分析

肉类研究 1989年第1期3卷 29-31页

作者：杨峥房其年张纯

胡椒(Piper Nigrum L.)为多年生藤本胡椒科植物.它的果实具有温中散寒、下气消痰等药效,同时其味辛辣而芳香,可促进食欲,适用于烩、烧、炸、清蒸、汤菜等的调味,作为一种香辛料,在肉食品工业和个人家庭中广泛使用.胡椒因采摘时节和加工... 详细信息

胡椒(Piper Nigrum L.)为多年生藤本胡椒科植物.它的果实具有温中散寒、下气消痰等药效,同时其味辛辣而芳香,可促进食欲,适用于烩、烧、炸、清蒸、汤菜等的调味,作为一种香辛料,在肉食品工业和个人家庭中广泛使用.胡椒因采摘时节和加工方法不同又分黑、白两种,在肉食加工中习惯用白胡椒.为搞清胡椒香气和其化学组成间的关系,以便研究添加胡椒对肉食品风味的作用,笔者运用静态顶空采样,用两种毛细管色谱柱GC/MS(气相色谱质谱联用法)

关键词：白胡椒静态顶空胡椒碱分离分析化学组成毛细管色谱柱肉食加工香气成分香辛料加工方法

Maneuver control at high angle of attack based on real-time optimization of integrated aero-propulsion

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Chinese Journal of Aeronautics 2022年第12期35卷 173-188页

作者： Juan fang Qiangang zheng Changpeng CAI Haibo zhang College of Energy and Power Engineering Nanjing University of Aeronautics and AstronauticsNanjing 210016China

To reduce the propulsion system installation thrust loss under high angle of attack maneuvering,a control method based on real-time optimization of the integrated aeropropulsion is ***,based on data fitting and physical principle,an integrated onboard model of propulsion system is established,which can calculate various performance parameters of the propulsion system in real time,and has high accuracy and real-time ***,to improve the compatibility of optimization real-time performance and search accuracy,the online optimization control of aero-propulsion system is realized based on an improved trust region ***,by controlling the auxiliary intake valve,a good match between inlet and engine is realized,which solves the problems of intake flow reducing and total pressure recovery coefficient declining,and improves the installation performance of propulsion *** simulation results indicate that,compared with the conventional independent engine control,the real-time integrated optimization method reduces the installed thrust loss by 3.61%under the design condition,and 4.58%under the off-design ***,the simulation on HIL(Hardware-In-theLoop)platform verifies the real-time performance of integrated optimization method.

关键词： High angle of attack Inlet/engine integration Real-time optimization Engine performance Auxiliary intake valve

Effect of Al_(2)O_(3) content on the viscosity and structure of CaO-SiO_(2)-Cr_(2)O_(3)-Al_(2)O_(3) slags

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International Journal of Minerals,Metallurgy and Materials 2022年第8期29卷 1522-1531页

作者： fang Yuan zheng Zhao Yanling zhang Tuo Wu State Key Laboratory of Advanced Metallurgy University of Science and Technology BeijingBeijing 100083China

The effect of Al_(2)O_(3) content on the viscosity and structure of CaO-SiO_(2)-Cr_(2)O_(3)Al_(2)O_(3) slags was investigated to facilitate recycling of Cr in steelmaking *** slags exhibit good Newtonian behavior at high *** viscosity of acidic slag first increases from 0.825 to 1.141 Pa·s as the Al_(2)O_(3) content increases from 0 to 10wt%and then decreases to 1.071 Pa·s as the Al_(2)O_(3) content increases further to 15wt%.The viscosity of basic slag first increases from 0.084 to 0.158 Pa·s as the Al_(2)O_(3) content increases from 0 to 15wt%and then decreases to 0.135 Pa·s as the Al_(2)O_(3) content increases further to 20wt%.Furthermore,Cr_(2)O_(3)containing slag requires less Al_(2)O_(3) to reach the maximum viscosity than Cr_(2)O_(3)free slag;the Al_(2)O_(3) contents at which the behavior changes are 10wt%and 15wt%for acidic and basic slags,*** ac-tivation energy of the slags is consistent with the viscosity *** spectra demonstrate that[AlO_(4)]tetrahedra appear initially and were replaced by[AlO_(6)]octahedra with further addition of Al_(2)O_(3).The dissolved organic phosphorus content of the slag first increases and then de-creases with increasing Al_(2)O_(3) content,which is consistent with the viscosity and Raman results.

关键词： viscosity structure Cr-containing slag Raman spectra

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电解水制氢技术:进展、挑战与未来展望

工程科学学报 2025年第2期47卷 282-295页

作者：张正宋凌珺北京航空航天大学交通科学与工程学院北京102200

实现全球碳中和是各国在2050年制定的重要目标之一,旨在减缓气候变化的不良影响.氢能作为一种极具潜力的清洁能源,凭借其高能量密度、零碳排放、可再生性强等特性,被视为实现能源转型与应对气候变化的重要载体.为了实现这些目标,利用电... 详细信息

实现全球碳中和是各国在2050年制定的重要目标之一,旨在减缓气候变化的不良影响.氢能作为一种极具潜力的清洁能源,凭借其高能量密度、零碳排放、可再生性强等特性,被视为实现能源转型与应对气候变化的重要载体.为了实现这些目标,利用电解水制取氢气已经成为解决全球碳中和问题的重要关键方案之一.本文综述了碱性电解水、质子交换膜电解水、阴离子交换膜电解水和固体氧化物电解水制氢技术的最新进展,并对这四种电解水技术的工作原理、结构特点以及优缺点进行了详尽比较.此外,总结了电解水制氢催化剂材料的研究进展,尤其是新型材料的开发与结构优化,旨在提升材料的催化活性与稳定性.讨论了海水电解制氢和耦合制氢等新兴技术,强调通过电解质组成优化、高效双功能催化剂开发及利用小分子氧化反应热力学优势,可有效提升电解水制氢效率和系统稳定性.最后,提出了电解水制氢技术的发展趋势与未来研究方向,包括提升催化剂性能、降低电解过程能耗、开发新型电解设备等,旨在促进电解水制氢技术的进步,助力全球碳中和目标的实现,并为未来的研究提供参考与指导.

关键词：碳中和氢能电解水制氢催化剂电极材料

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Advances and applications in single-cell and spatial genomics

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Science China Life Sciences 2025年

作者： Jingjing Wang fang Ye Haoxi Chai Yujia Jiang Teng Wang Xia Ran Qimin Xia Ziye Xu Yuting Fu Guodong zhang Hanyu Wu Guoji Guo Hongshan Guo Yijun Ruan Yongcheng Wang Dong Xing Xun Xu Zemin zhang Beijing Advanced Innovation Center for Genomics (ICG) Peking University Guangdong Provincial Key Laboratory of Genome Read and Write BGI Research Bone Marrow Transplantation Center of the First Affiliated Hospital & Liangzhu Laboratory Zhejiang University School of Medicine Life Sciences Institute and The Second Affiliated Hospital Zhejiang University BGI Research Biomedical Pioneering Innovation Center (BIOPIC) and School of Life Sciences Peking University Academy for Advanced Interdisciplinary Studies Peking University Institute of Hematology Zhejiang University Department of Laboratory Medicine of The First Affiliated Hospital & Liangzhu Laboratory Zhejiang University School of Medicine Center for Stem Cell and Regenerative Medicine Zhejiang University School of Medicine Zhejiang Provincial Key Lab for Tissue Engineering and Regenerative Medicine Dr.Li Dak Sum & Yip Yio Chin Center for Stem Cell and Regenerative Medicine

The applications of single-cell and spatial technologies in recent times have revolutionized the present understanding of cellular states and the cellular heterogeneity inherent in complex biological systems. These advancements offer unprecedented resolution in the examination of the functional genomics of individual cells and their spatial context within tissues. In this review, we have comprehensively discussed the historical development and recent progress in the field of single-cell and spatial genomics. We have reviewed the breakthroughs in single-cell multi-omics technologies, spatial genomics methods, and the computational strategies employed toward the analyses of singlecell atlas data. Furthermore, we have highlighted the advances made in constructing cellular atlases and their clinical applications,particularly in the context of disease. Finally, we have discussed the emerging trends, challenges, and opportunities in this rapidly evolving field.

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Multivariable sliding mode backstepping controller design for quadrotor UAV based on disturbance observer

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Science China(Information Sciences) 2018年第11期61卷 155-170页

作者： zheng zhang fang WANG Ying GUO Changchun HUA School of Science Yanshan University School of Electric Engineering Yanshan University

This paper deals with the tracking control problem of quadrotor unmanned aerial vehicles(QUAVs) with external disturbances. First, because the QUAV model contains two non-integrity constraints,the dynamic model of the QUAV is decomposed into two subsystems which are independently controlled, so as to reduce controller design complexity. Secondly, the nonlinear disturbance observer(DOB) technique is integrated into a backstepping control method to design the controller for the first subsystem, in which a DOB is applied to estimate the lumped uncertainty. Based on the double power reaching law and the DOB,a multivariable sliding mode control(MSMC) scheme is developed for the second subsystem. Thirdly, based on Lyapunov theory, the closed-loop system is proved to be asymptotically stable. Finally, our comparative simulation results demonstrate that the presented control scheme behaves better in terms of tracking performance than the adaptive backstepping control(ABC) approach.

关键词： quadrotor unmanned aerial vehicle QUAV nonlinear DOB backstepping control sliding mode control power reaching law

Evolution of carbides on surface of carburized MSONiL bearing steel

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Journal of Iron and Steel Research International 2018年第11期25卷 1198-1211页

作者： Jiang-long Lian Li-jing zheng fang-fang Wang Hu zhang School of Materials Science and Engineering Beihang UniversityBeijing 100191China

The dissolution and precipitation behaviors of the carbides in carburized M50NiL steel were derived from different solution and tempering *** four kinds of carbides of (V,Cr)-rich MC,(Mo,Fe)-rich M2C,Fe-rich M3C and (Fe,Cr)-rich M7C3 were obtained from the carburized M50NiL steel after different heat *** key carbides of carbufized M50NiL steel were proved to be tough V-rich MC and Cr-rich *** highest hardness (634 HV)and the optimal surface structure with 1.0% volume fraction of uniformly distributed MC carbides were obtained after the carbufized M50NiL steel was solution-treated at 1150 ℃ and tempered at 500 ℃.The quantitative statistics show that 63%of the MC carbides were less than 200 nm under that heat *** variety of carbides changed with solution and tempering *** the solution temperature increased from 1050 to 1150 ℃,the undissolved carbides were proved to be Fe-rich M7C3,Mo-fich MC and (Mo,Fe)-fich ***,the equivalent content of V-rich MC was found increased when the tempering temperature changed from 500 to 550 ℃.The combination of high-temperature solution and low-temperature tempering is recommendable heat treatment for the high hardness as well as the tiny and uniformly distributed carbides.

关键词： M50NiL steel Carbide Carburization Hardness Heat treatment

Leader-follower: Human-centered intention-guided controller for novel SuperLimb with application to load-carrying scenarios

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Science China Technological Sciences 2025年第1期 325-338页

作者： Qinghua zhang Xianglong LI Hongwei JING Kerui SUN Yuancheng LI Sikai ZHAO Lele LI Haotian JU Ziqi WANG Rui WU Tianjiao zheng Jie ZHAO Yanhe ZHU The State Key Laboratory of Robotics and System Harbin Institute of Technology The Learning Algorithms and Systems Laboratory School of Engineeringécole Polytechnique Fédérale de Lausanne

Supernumerary robotic arms(SuperLimb) are a new type of wearable robot that works closely with humans as a third hand to augment human operation capability. Accurate conveyance of wearers' intentions, allocation of roles, and humancentered interaction considerations are the key points in the process of human–SuperLimb collaboration. This paper proposes a human-centered intention-guided leader–follower controller that relies on the dynamic modeling of SuperLimb with application to load-carrying scenarios. The proposed leader–follower controller takes the human as the leader and the SuperLimb as the follower, achieving effective information communication, autonomous coordination, and good force compliance between SuperLimb, humans, and the environment under human safety assurance. First, the human–SuperLimb dynamic system is modeled to achieve force interaction with the environment and wearer. Second, to achieve the precise intention extraction of humans, pose data from five visual odometry sensors are fused to capture the human state, the generalized position, the velocity of hands, and the surface electromyography signals from two myoelectric bracelets sensors are processed to recognize the natural hand gestures during load-carrying scenarios by a designed Swin transformer network. Then, based on the real-time distance detection between human and mechanical limbs, the security assurance and force-compliant interaction of the human–SuperLimb system are realized. Finally, the human hand muscle intention recognition, human–robot safety strategy verification,and comparative load-carrying experiments with and without the proposed method are conducted on the SuperLimb *** showed that the task parameters are well estimated to produce more reasonable planning trajectories, and SuperLimb could well understand the wearer's intentions to switch different SuperLimb actions. The proposed sensor-based human–robot communication framework motivates future studies of o

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生地黄有效成分梓醇药理作用机制研究进展

上海中医药杂志 2017年第2期51卷 93-97页

作者：黄传君赵方正张才擎山东中医药大学山东济南250014 山东大学千佛山医院呼吸内科山东济南250014

综述生地黄有效成分梓醇药理作用机制研究进展。梓醇是中药地黄有效成分之一,具有降血糖、保护神经、保护心脏、抗肿瘤的作用。

关键词：梓醇药理作用机制