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Spreading-rate dependence of hydroacoustic and teleseismic seismicity of ridge-transform systems:East Pacific Rise,Galapagos Ridge,and Mid-Atlantic Ridge

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Acta Oceanologica Sinica 2022年第5期41卷 124-135页

作者： tingting zheng Jian Lin Qiu Zhong Key Laboratory of Ocean and Marginal Sea Geology South China Sea Institute of OceanologyInnovation Academy of South China Sea Ecology and Environmental EngineeringChinese Academy of SciencesGuangzhou510301China Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou) Guangzhou511458China China-Pakistan Joint Research Center on Earth Sciences Chinese Academy of Science-Higher Education Commission(Pakistan)Islamabad45320Pakistan Department of Ocean Science and Engineering Southern University of Science and TechnologyShenzhen518055China Department of Geology and Geophysics Woods Hole Oceanographic InstitutionFalmouthWoods HoleMA02543USA

Seismicity in ocean ridge-transform systems reveals fundamental processes of mid-ocean ridges,while comparisons of seismicity in different oceans remain rare due to a lack of detection of small *** 1996 to 2003,the Pacific Marine Environmental Laboratory of the National Oceanic and Atmospheric Administration(NOAA/PMEL)deployed several hydrophones in the eastern Pacific Ocean and the northern Atlantic *** hydrophones recorded earthquakes with small magnitudes,providing us with opportunities to study the seismic characteristics of ridge-transform systems at different spreading rates and make further comparisons of their *** study comparatively analyzed hydroacoustic and teleseismic data recorded on the fast-spreading East Pacific Rise(EPR,10°S to 12°N),intermediate-spreading Galapagos Ridge(103°W to 80°W),and slow-spreading Mid-Atlantic Ridge(MAR,15°N to 37°N).We present a systematic study of the spatial and temporal distribution of events,aftershock seismicity,and possible triggering mechanisms of aftershock *** analysis yields the following conclusions.(1)From the hydroacoustic data,the EPR transform faults had the highest average seismicity rate among the three regions.(2)Along-ridge event distributions show that a high number of earthquakes were concentrated on the EPR,while they became dispersed on the GR and fewer and more scattered on the MAR,reflecting that the different tectonic origins were closely correlated with the spreading rate.(3)Analysis from mainshock-aftershock sequences shows no significant differences in the aftershock decay rate among the three regions.(4)Multiple types of aftershock triggering models were inferred from Coulomb stress changes:strike-slip mainshocks triggered strike-slip aftershocks and normal faulting aftershocks,and normal faulting mainshocks triggered normal faulting *** these results are case studies,they may be applicable to other ocean ridge-transform systems in future

关键词： East Pacific Rise Galapagos Ridge Mid-Atlantic Ridge hydroacoustic and teleseismic seismicity ridge-transform system

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On the stability of contact discontinuity for Cauchy problem of compress Navier-Stokes equations with general initial data

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Science China Mathematics 2012年第10期55卷 2005-2026页

作者： zheng tingting ZHAO JunNing School of Mathematical Sciences Xiamen UniversityXiamen 361005China School of Computer and Information Science Fujian Agriculture and Forestry UniversityFuzhou 350002China

Abstract In this paper, we study the stability of solutions of the Cauchy problem for 1-D compressible Narvier- Stokes equations with general initial data. The asymptotic limit of solution is found, under some conditions. The results in this paper imply the case that the limit function of solution as t → ee is a viscous contact wave in the sense, which approximates the contact discontinuity on any finite-time interval as the heat conduction coefficients toward zero. As a by-product, the decay rates of the solution for the fast diffusion equations are also obtained. The proofs are based on the elementary energy method and the study of asymptotic behavior of the solution to the fast diffusion equation.

关键词： compressible N-S equations weak solution large-time behavior

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On the Cauchy problem for a doubly nonlinear degenerate parabolic equation with strongly nonlinear sources

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Science China Mathematics 2008年第11期51卷 2059-2071页

作者： zheng tingting ZHAO JunNing School of Mathematical Sciences Xiamen UniversityXiamen 361005China

In this article, we consider the existence of local and global solution to the Cauchy problem of a doubly nonlinear equation. By introducing the norms |||f||| h and 〈f〉h, we give the sufficient and necessary conditions on the initial value to the existence of local solution of doubly nonlinear equation. Moreover some results on the global existence and nonexistence of solutions are considered.

关键词： degenerate parabolic nonlinear sources global and local solutions 35K65 35K55

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SERS and EC dual-mode detection for dopamine based on WO_(3)-SnO_(2)nanoflake arrays

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Nano Research 2023年第3期16卷 4049-4054页

作者： Linya Lu Yan Zhou tingting zheng Yang Tian School of Chemistry and Molecular Engineering East China Normal UniversityShanghai 200241China State Key Laboratory of Precision Spectroscopy East China Normal UniversityShanghai 200241China

As an important neurotransmitter,the detection of dopamine(DA)is of great significance for the diagnosis and treatment of neurological *** this study,WO_(3)-SnO_(2)nanoflake arrays were synthesized on fluorine-doped tin oxide(FTO)by hydrothermal synthesis and pulse electrodeposition,revealing significant surface-enhanced Raman scattering(SERS)activity with an enhancement factor(EF)reaching 4.79×10^(7).The obvious EF was mainly ascribed to the charge transfer between WO_(3)-SnO_(2)and methylene blue(MB)based on chemical mechanism(CM)and the molecular resonance *** the competitive adsorption of DA and absorbed MB,we prepared a SERS and electrochemical(EC)dual-mode detection platform of DA based on the WO_(3)-SnO_(2)nanoflake *** linear range(LR)was 5.00-1.75×10^(3)nmol/L,and the detection limits(LODs)were as low as 1.50 and 0.80 nmol/L by SERS and EC ***,the developed detection platform can shield the interference of many neurotransmitters similar to DA,showing good selectivity and excellent *** general,the SERS-EC dual-mode detection platform can be well applied to the detection of DA in cell lysate,demonstrating great potential in diagnosis of neurodegenerative diseases.

关键词： surface enhanced Raman scattering electrochemical WO3-SnO2 nanoflake arrays charge transfer dopamine

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Exosomes in Parkinson's Disease

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Neuroscience Bulletin 2017年第3期33卷 331-338页

作者： Xiaoqing Wu tingting zheng Baorong Zhang Department of Neurology Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009China Department of Neurology Xinchang People's HospitalXinchang 312500China

Exosomes, nano-sized extracellular vesicles secreted by most cell types, are found in all kinds of biological fluids and tissues, including the central nervous system（CNS）. The proposed functions of these vesicles include roles in cell–cell signaling, removal of cellular debris, and transfer of pathogens between cells. Many studies have revealed that exosomes derived from the CNS occur in the cerebrospinal fluid and peripheral body fluids,and their contents are altered during disease, making them an appealing target for biomarker development in Parkinson＇s disease（PD）. Exosomes have been shown to spread toxic a-synuclein（asyn） between cells and induce apoptosis, which suggests a key mechanism underlying the spread of asyn aggregates in the brain and the acceleration of pathology in PD. However, potential neuroprotective roles of exosomes in PD have also been reported. On the treatment side, as drug delivery vehicles, exosomes have been used to deliver small interfering RNAs and catalase to the brain, and have shown clear therapeutic effects in a mouse model of PD. These features of exosomes in PD make them extremely interesting from the point of view of developing novel diagnostic and therapeutic approaches.

关键词： Exosomes Parkinson’s disease Biomarker Pathology Therapy

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Hot compressive deformation behaviors of Mg–10Gd–3Y–0.5Zr alloy

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Progress in Natural Science:Materials International 2016年第1期26卷 78-84页

作者： tingting zheng Dejiang Li Xiaoqin Zeng Wenjiang Ding National Engineering Research Center of Light Alloy Net Forming School of Materials Science and Engineering Shanghai Jiao Tong University

In this paper, the hot compressive deformation characteristics of a Mg–10Gd–3Y–0.5Zr（GW103K） alloy have been investigated by isothermal compression test at the temperature range of 350–450°C and strain rate range of 0.0001–0.1s-1. True stress–strain relationships at various strain rates showed the typical strain hardening and softening stage which is indicative of dynamic recrystallization during deformation. The results showed that the peak stress was obviously dependent on temperature and strain rate. A constitutive equation to describe the deformation process was established based on the hyperbolic sine function. The stress exponent n and apparent activation energy Q were determined to be 3.018 and 203.947 k J/mol, respectively. Microstructure investigation showed that dislocation slipping was the dominant deformation mechanism during the hot deformation at all conditions. However, at the temperatures lower than 400 °C and strain rates higher than 0.01 s-1, twinning was observed to be activated, which indicated another deformation mechanism. Dynamic recrystallization and dynamic precipitation were found to occur simultaneously under such deformation condition.

关键词： Mg-RE alloys Hot deformation Dynamic precipitation Constitutive equation Microstructure evolution

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Surface-enhanced Raman Scattering Technology Based on WO_(3) Film for Detection of VEGF

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Chemical Research in Chinese Universities 2021年第4期37卷 900-905页

作者： LIU Xiaoyan ZHOU Yan zheng tingting TIAN Yang School of Chemistry and Molecular Engineering East China Normal UniversityShanghai200241P.R.China State Key Laboratory of Precision Spectroscopy East China Normal UniversityShanghai200241P.R.China

With the advancement of nanomaterials for surface-enhanced Raman scattering(SERS) detection, a deeper understanding of the chemical mechanism(CM) and further applications has been achieved. Herein, we prepared a porous tungsten trioxide(WO_(3)) film by the pulse electrodeposition method, and constructed a WO3 film SERS aptasensor. With methylene blue(MB) as the adsorption molecule, the developed WO_(3) film SERS aptasensor revealed remarkable Raman activity. Through experimental data and theoretical calculations, we found that the significant SERS enhancement[enhancement factor(EF)=1.5× 10^(6)] was due to the CM based on charge transfer and molecular resonance. Utilizing the Raman response of MB on the WO3 film and specific aptamers, we successfully developed the aptamer sensor by covalently attaching the MB modified aptamer to the WO_(3) film. The sensor realized the specific and sensitive determination of vascular endothelial growth factor(VEGF) with the detection limit down to 8.7 pg/mL. In addition, the developed aptasensor indicated the excellent selectivity among other interferences, such as metal ions, reactive oxygen species(ROS), and proteins. This WO3 film SERS aptasensor not only contributed to the study of the enhancement mechanism of semiconductor material, but also provided a powerful platform for the sensitive detection of VEGF, possessing a great potential in the real-time monitoring of biomarkers of glioblastoma in vitro.

关键词： Glioblastoma WO_(3) Charge transfer Vascular endothelial growth factor(VEGF) Surface-enhanced Raman scattering

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Surface-enhanced Raman Scattering on 2D Nanomaterials:Recent Developments and Applications

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Chinese Journal of Chemistry 2021年第3期39卷 745-756页

作者： tingting zheng Yan Zhou Enduo Feng Yang Tian Shanghai Key Laboratory of Green Chemistry and Chemical Processes Department of ChemistrySchool of Chemistry and Molecular EngineeringEast China Normal UniversityDongchuan Road 500Shanghai 200241China State Key Laboratory of Precision Spectroscopy East China Normal UniversityDongchuan Road 500Shanghai 200241China

Surface enhanced Raman spectroscopy(SERS)has emerged as a highly powerful and sensitive tool for molecular *** the various factors that affect SERS performance,substrate material is the most *** first observed in 1974,noble metals have been the most common substrates for ***,their increasing defects including low selectivity,weak uniformity,and poor stability are all obstacles to these noble metal-based SERS ***,due to the unique layer-dependent optical properties and a very large surface-to-volume ratio,two-dimensional(2D)nanomaterials are found to be promising candidates to overcome the shortcomings of a conventional metallic SERS ***,we concentrate on the latest development and applications of SERS-active 2D nano-materials in our group as well as in other related research *** enhancement mechanism of the SERS effect and the development of various SERS-active 2D nanomaterials have been discussed in ***,the latest development in 2D nanomaterial-SERS based analytical applications from trace detection of small organic pollutants and macromolecular biomarkers to in-situ cytosensing and in-situ theranostic analysis is introduced.

关键词： Raman spectroscopy 2D nanomaterials Heterostructures Reaction mechanisms SERS sensing

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新课标背景下小学英语作业设计研究

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英语教师 2025年第1期 44-46页

作者：徐静静郑婷婷江苏省连云港市解放路小学江苏连云港222000

介绍新课标背景下小学英语作业设计的原则,即趣味性、生活性、层次性、融合性。结合教学实例,探索新课标背景下小学英语作业设计的策略,即设计趣味性作业,增强学生的学习动力;设计生活性作业,落实学生的语言应用;设计层次性作业,促进学... 详细信息

介绍新课标背景下小学英语作业设计的原则,即趣味性、生活性、层次性、融合性。结合教学实例,探索新课标背景下小学英语作业设计的策略,即设计趣味性作业,增强学生的学习动力;设计生活性作业,落实学生的语言应用;设计层次性作业,促进学生的个性发展;设计融合性作业,培养学生的综合能力。认为教师设计趣味性、生活性、层次性、融合性的英语作业,能有效促进学生英语综合素养和综合能力的发展。

关键词：新课标小学英语作业设计

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Induced neural stem/precursor cells for fundamental studies and potential application in neurodegenerative diseases

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Neuroscience Bulletin 2015年第5期31卷 589-600页

作者： Ting Shen Jiali Pu tingting zheng Baorong Zhang Department of Neurology Second Affi liated Hospital School of Medicine Zhejiang University

Recent research has shown that defined sets of exogenous factors are sufficient to convert rodent and human somatic cells directly into induced neural stem cells or neural precursor cells（iNSCs/iNPCs）.The process of transdifferentiation bypasses the step of a pluripotent state and reduces the risk of tumorigenesis and genetic instability while retaining the self-renewing *** iNSC/iNPC technology has fueled much excitement in regenerative medicine,as these cells can be differentiated into target cells for replacement therapy for neurodegenerative ***＇ somatic cell-derived iNSCs/iNPCs have also been proposed to serve as disease models with potential value in both fundamental studies and clinical *** review focuses on the mechanisms,techniques,and applications of iNSCs/iNPCs from a series of related studies,as well as further efforts in designing novel strategies using iNSC/iNPC technology and its potential applications in neurodegenerative diseases.

关键词： induced neural stem cell induced neural precursor cell transdifferentiation fundamental study clinical application neurodegenerative disease

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