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云南8个地区食蚊鱼种群的遗传结构分析

西南林业大学学报（自然科学） 2017年第4期37卷 113-119页

作者：秦凯波仇玉萍郑毅西南林业大学国家高原湿地研究中心云南昆明650224 云南省教育厅云南昆明650223

利用线粒体细胞色素b基因序列对云南8个不同地理种群食蚊鱼的遗传结构进行了分析,并对8个地理种群共计210个样本进行PCR扩增;采用分子方差分析方法,对种群的遗传变异进行分析。结果表明:获得了786 bp的基因片段序列,共检测到5个多态位点... 详细信息

利用线粒体细胞色素b基因序列对云南8个不同地理种群食蚊鱼的遗传结构进行了分析,并对8个地理种群共计210个样本进行PCR扩增;采用分子方差分析方法,对种群的遗传变异进行分析。结果表明:获得了786 bp的基因片段序列,共检测到5个多态位点,定义了5种单倍型,其中单倍型H1由7个地理种群的156个样本共享(占样本总量74.3%),单倍型H2由7个地理种群的52个样本共享(占样本总量24.8%)。碱基频率含量(A+T)为53.2%,大于(G+C)46.8%。核苷酸多态性以东大河种群最高,其他7个群体较低。种群间的基因流较小为0.28。种群间遗传变异占总变异的52.74%,种群内的遗传变异占总变异的47.26%,种群间的变异是总变异的主要来源,云南地区的食蚊鱼种群整体较为稳定。

关键词：食蚊鱼线粒体DNA 单倍型基因种群遗传变异

Microstructure and Mechanical Property of the Large Cross-Sectioned Mg-Gd-Y-Zn-Zr Alloy Produced by Small Extrusion Ratio

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Acta Metallurgica Sinica(English Letters) 2024年第6期37卷 999-1006页

作者： Sen Wang Hucheng Pan Caixia Jiang Zhihao Zeng Zhen Pan Weineng Tang Chubin Yang yuping Ren Gaowu Qin Key Laboratory for Anisotropy and Texture of Materials(Ministry of Education) College of Materials Science and EngineeringNortheastern UniversityShenyang110819China Mg and Mg Alloy Institute Technology CenterBaosteel Metal Co.LtdChina Baowu Steel GroupShanghai200940China Jiangxi Provincial Engineering Research Center for Magnesium Alloy Gannan Normal UniversityGanzhou341000China

In this work,the microstructure and mechanical properties of large cross-sectioned Mg-9Gd-3Y-1.2Zn-0.5Zr(VWZ931)samples produced by the small extrusion ratio has been *** as-extruded VWZ931 sample with diameter of~30 mm can exhibit the high yield strength(YS)of 339 MPa,ultimate tensile strength(UTS)of 387 MPa and elongation of 8.2%,*** peak-aged,the YS and UTS of the Mg samples were significantly increased to 435 MPa and 467 *** small extrusion ratio leads to the low fraction of dynamic recrystallized(DRX)grains in VWZ931 sample,and the texture hardening effect can be fully utilized to achieve high *** combined effect of precipitation strengthening due to the long-period stacking ordered phases and theβ′phase,grain boundary strengthening due to the fine DRX grains,heterogeneous deformation-induced strengthening caused by bimodal microstructure,can together contribute to the high strength of present Mg *** findings can shed light on designing other large-sized Mg wrought alloys with high mechanical performance.

关键词： Mg-RE alloy Mechanical property Bimodal grains Texture hardening

Damping Characteristic Analysis and Optimization of Wind-thermal-bundled Power Transmission by LCC-HVDC Systems

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Journal of Modern Power Systems and Clean Energy 2024年第1期12卷 299-312页

作者： Liwen zheng Shiying Ma the Power System Department China Electric Power Research InstituteBeijing 100192China

With the rapid development of renewable energy,wind-thermal-bundled power transmission by line-commutated converter based high-voltage direct current(LCC-HVDC)systems has been widely *** dynamic interaction mechanisms among permanent magnet synchronous generators(PMSGs),synchronous generators(SGs),and LCC-HVDC system become *** deal with this issue,a path analysis method(PAM)is proposed to study the dynamic interaction mechanism,and the damping reconstruction is used to analyze the damping characteristic of the ***,based on the modular modeling,linearized models for the PMSG subsystem,the LCC-HVDC subsystem,and the SG subsystem are ***,based on the closed-loop transfer function diagram of the system,the disturbance transfer path and coupling relationship among subsystems are analyzed by the PAM,and the damping characteristic analysis of the SG-dominated oscillation mode is studied based on the damping *** with the PAM,the small-signal model of the system is obtained and eigenvalue analysis results are ***,the effect of the control parameters on the damping characteristic is analyzed and the conclusions are verified by time-domain ***,the penalty functions of the oscillation modes and decay modes are taken as the objective function,and an optimization strategy based on the Monte Carlo method is proposed to solve the parameter optimization *** simulation results are presented to validate the effectiveness of the proposed strategy.

关键词： Wind-thermal-bundled power transmission line-commutated converter based high-voltage direct current(LCC-HVDC) path analysis method(PAM) damping characteristic analysis Monte Carlo method

Can near-to-mid Infrared Spectral Energy Distribution Quantitatively Trace Protoplanetary Disk Evolution?

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Research in Astronomy and Astrophysics 2024年第7期24卷 34-46页

作者： Mingchao Liu Jinhua He Zhen Guo Jixing Ge yuping Tang Yunnan Observatories Chinese Academy of SciencesKunming 650216China Chinese Academy of Sciences South America Center for Astronomy National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China Departamento de Astronomía Universidad de ChileLas Condes7591245 SantiagoChile Instituto de Física y Astronomía Universidad de Valparaísoave.Gran Bretaña1111Casilla 5030ValparaísoChile Centre for Astrophysics Research University of HertfordshireHatfield AL109ABUK Millennium Institute of Astrophysics Nuncio Monseñor Sotero Sanz 100Of.104ProvidenciaSantiagoChile Xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 830011China Xinjiang Key Laboratory of Radio Astrophysics Urumqi 830011China Shanghai Key Lab for Astrophysics Shanghai Normal UniversityShanghai 200234China

Infrared(IR)spectral energy distribution(SED)is the major tracer of protoplanetary *** was recently proposed to use the near-to-mid IR(or K-24)SED slopeαdefined between 2 and 24μm as a potential quantitative tracer of disk *** critically examine the viability of this idea and confront it with additional statistics of IR luminosities and SED *** point out that,because the statistical properties of most of the complicated physical factors involved in disk evolution are still poorly understood in a quantitative sense,the only viable way is to assume them to be random so that an idealized“average disk”can be defined,which allows theαhistogram to trace its *** confirm that the statistics of the zeroth order(luminosity),first order(slopeα),and second order characteristics(concavity)of the observed K-24 SEDs indeed carry useful information upon the evolutionary processes of the“average disk”.We also stress that intrinsic diversities in K-24 SED shapes and luminosities are always large at the level of individual stars so that the application of the evolutionary path of the“average disk”to individual stars must be done with *** data of most curves in plots are provided on GitHub(Disk-age package https://***/starage/disk-age/).

关键词： stars formation-stars pre-main sequence-stars protostars-infrared stars-protoplanetary disks

区域创新体系对产业集群发展的适应性评价研究

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中国科技论坛 2010年第12期 43-49页

作者：张良强郑雨苹周颖福州大学软科学研究所福建福州350002 福建省科技促进发展研究中心福建福州350003

针对我国区域经济中存在产业集群的发展与区域创新体系的主体要素和功能分离的现象,提出了区域创新体系与产业集群的关联性概念,在此基础上,构建了从地域关联、结构关联、功能关联及目标关联等四个维度评价区域创新体系对产业集群发展... 详细信息

针对我国区域经济中存在产业集群的发展与区域创新体系的主体要素和功能分离的现象,提出了区域创新体系与产业集群的关联性概念,在此基础上,构建了从地域关联、结构关联、功能关联及目标关联等四个维度评价区域创新体系对产业集群发展的适应度的指标体系和方法,并以福建省为例,进行了实证的评价与分析,为寻求完善区域创新体系的思路和方法提供了一个新的视角。

关键词：区域创新体系产业集群关联性适应度评价

Association between the frontoparietal network,clinical symptoms and treatment response in individuals with untreated anorexia nervosa

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General Psychiatry 2024年第3期37卷 364-374页

作者： Qianqian He Hui zheng Jialin Zhang Ling Yue Qing Kang Cheng Lian Lei Guo Yan Chen Yanran Hu yuping Wang Sufang Peng Zhen Wang Qiang Liu Jue Chen Department of Clinical Psychology Shanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghaiChina Department of Clinical Psychology Shanghai Pudong New Area Mental Health CenterTongji University School of MedicineShanghaiChina Shanghai Key Laboratory of Psychotic Disorders Brain Health InstituteNational Center for Mental DisordersShanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghaiChina State Key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern Institute for Brain Research Bejing Normal UniversityBeijingChina

Background Anorexia nervosa(AN)has been characterised as a psychiatric disorder associated with increased ***,it remains difficult to predict treatment response in patients with *** cognitive abilities are known to be resistant to *** has been established that the frontoparietal control network(FPCN)is the direct counterpart of the executive control ***,the resting-state brain activity of the FPCN may serve as a biomarker to predict treatment response in *** The study aimed to investigate the association between resting-state functional connectivity(RSFC)of the FPCN,clinical symptoms and treatment response in patients with *** In this case-control study,79 female patients with AN and no prior treatment from the Shanghai Mental Health Center and 40 matched healthy controls(HCs)were recruited from January 2015 to March *** participants completed the Questionnaire Versionof the Eating Disorder Examination(version 6.0)to assess the severity of their eating disorder ***,RSFC data were obtained from all participants at baseline by functional magnetic resonance *** with AN underwent routine outpatient treatment at the 4th and 12th week,during which time their clinical symptoms were evaluated using the same measures as at *** Among the 79 patients,40 completed the 4-week follow-up and 35 completed the 12-week *** RSFC from the right posterior parietal cortex(PPC)and dorsolateral prefrontal cortex(diPFC)increased in 79 patients with AN vs 40 HCs after controlling for depression and anxiety *** multiple linear regression,the RSFC of the PPC to the inferior frontal gyrus was found to be a significant factor for self-reported eating disorder symptoms at baseline and the treatment response to cognitive preoccupations about eating and body image,after controlling for age,age of onset and body mass *** RSFC in the dIPFC to the middle temporal gyrus and the

关键词： symptoms routine prevention

A stepwise-responsive editor integrated with three copper ions for the treatment of oral squamous cell carcinoma

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Nano Research 2024年第6期17卷 5424-5434页

作者： Jinna Ren Jingying Hu Fan Dong Yan Xu Yang Peng yuping Qian Guanmeng Zhang Min Wang Yuguang Wang Department of Prosthodontics Hospital of StomatologyJilin UniversityChangchun 130021China Department of General Dentistry II Peking University School and Hospital of Stomatology&National Center for Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Research Center of Oral Biomaterials and Digital Medical DevicesBeijing 100081China Center of Digital Dentistry Peking University School and Hospital of Stomatology&National Center for Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Research Center of Oral Biomaterials and Digital Medical DevicesBeijing 100081China Department of Nursing Peking University School and Hospital of Stomatology&National Center for Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Research Center of Oral Biomaterials and Digital Medical DevicesBeijing 100081China The VIP Department School and Hospital of StomatologyChina Medical UniversityLiaoning Provincial Key Laboratory of Oral DiseasesShenyang 110002China

Cuprotosis,a new type of cell death,provides great opportunities for the treatment of oral squamous cell carcinoma,as nanocarriers of copper ions can induce cuprotosis and immunogenic ***,we studied an editor that enables production of a nanoparticle“storm”in oral squamous cell carcinoma,maximizing the toxic effect of these particles and reprogramming the tumor microenvironment;as a result,T cells and natural killer(NK)cells can infiltrate the tumor microenvironment to activate an antitumor immune *** this basis,the editor can be combined with optical therapy to improve patient *** this study,the metal ratio was regulated in response to the nanocarrier of acid response ***,in the presence of a specific copper ion content,the nanocarrier could change the permeability of the tumor cell *** on these results,the nanoparticles were cracked in an acidic environment and then released copper ***,the nanoparticles contributed to cuprotosis and immunogenic *** addition,the editor could inhibit murine oral cancer 1(MOC1)tumors in C57BL/6 without *** rate of tumor growth inhibition was as high as approximately 80%.This strategy provides a new idea for ***,it can improve the interaction between immunotherapy and the copper-induced death of oral squamous cell *** all,this study will provide a new opportunity for the effective treatment of oral squamous cell carcinoma.

关键词： cuprotosis immunogenic death photothermal therapy tumor microenvironment immunotherapy

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一种新的双回线单端相继速动保护的实现

电力系统自动化 2008年第17期32卷 61-65页

作者：程文君郑玉平张哲程兰芳国网电力科学研究院/南京南瑞集团公司江苏省南京市210003 南京南瑞继保电气有限公司江苏省南京市211100 宣城市供电公司安徽省宣城市242000

分析了现有双回线单端保护的优缺点以及两回线间零序互感对接地距离继电器的影响,在现有双回线微机保护装置的硬件平台上实现了由几个改进元件共同组合构成的新的双回线单端相继速动保护判据,并经动模试验验证了该保护在区外故障时可靠... 详细信息

分析了现有双回线单端保护的优缺点以及两回线间零序互感对接地距离继电器的影响,在现有双回线微机保护装置的硬件平台上实现了由几个改进元件共同组合构成的新的双回线单端相继速动保护判据,并经动模试验验证了该保护在区外故障时可靠不动作,区内除了母线出口处发生同名跨线故障时远故障端保护要以距离Ⅱ段延时动作外,其他跨线故障以及全线范围的单回线故障均能正确地快速动作。

关键词：同杆双回线相继速动保护零序互感运行方式单端保护

A Minimum Residual Based Gradient Iterative Method for a Class of Matrix Equations

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Acta Mathematicae Applicatae Sinica 2024年第1期40卷 17-34页

作者： Qing-qing zheng Department of Mathematics College of ScienceChina University of Petroleum-BeijingBeijing102249China

In this paper, we present a minimum residual based gradient iterative method for solving a class of matrix equations including Sylvester matrix equations and general coupled matrix equations. The iterative method uses a negative gradient as steepest direction and seeks for an optimal step size to minimize the residual norm of next iterate. It is shown that the iterative sequence converges unconditionally to the exact solution for any initial guess and that the norm of the residual matrix and error matrix decrease monotonically. Numerical tests are presented to show the efficiency of the proposed method and confirm the theoretical results.

关键词： Sylvester matrix equation coupled matrix equation minimum residual gradient descent convergence analysis