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Brain plasticity after peripheral nerve injury treatment with massage therapy based on resting-state functional magnetic resonance imaging

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Neural Regeneration Research 2021年第2期16卷 388-393页

作者： Xiang-Xin Xing Mou-Xiong zheng Xu-Yun Hua Shu-Jie ma zhen-zhen ma Jian-Guang Xu School of Rehabilitation Science Shanghai University of Traditional Chinese MedicineShanghaiChina Department of Rehabilitation Medicine Yueyang HospitalShanghai University of Traditional Chinese MedicineShanghaiChina Department of Traumatology and Orthopedics Yueyang HospitalShanghai University of Traditional Chinese MedicineShanghaiChina Yangzi Rehabilitation Hospital Tongji UniversityShanghaiChina

massage therapy is an alternative treatment for chronic pain that is potentially related to brain ***,the underlying mechanism remains *** established a peripheral nerve injury model in rats by unilateral sciatic nerve transection and direct *** experimental rats were treated over the gastrocnemius muscle of the affected hindlimb with a customized massage instrument(0.45 N,120 times/min,10 minutes daily,for 4 successive weeks).Resting-state functional magnetic resonance imaging revealed that compared with control rats,the amplitude of low-frequency fluctuations in the sensorimotor cortex contralateral to the affected limb was significantly lower after sciatic nerve ***,amplitudes were significantly higher in the massage group than in a sham-massage *** findings suggest that massage therapy facilitated adaptive change in the somatosensory cortex that led to the recovery of peripheral nerve injury and *** study was approved by the Animal Ethics Committee of Shanghai University of Traditional Chinese Medicine of China(approval No.201701001)on January 12,2017.

关键词： injury massage model neuron peripheral nerve plasticity rat repair

Electroacupuncture treatment improves motor function and neurological outcomes after cerebral ischemia/reperfusion injury

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Neural Regeneration Research 2022年第7期17卷 1545-1555页

作者： Si-Si Li Xu-Yun Hua Mou-Xiong zheng Jia-Jia Wu zhen-zhen ma Xiang-Xin Xing Jie ma Chun-Lei Shan Jian-Guang Xu School of Rehabilitation Science Shanghai University of Traditional Chinese MedicineShanghaiChina Department of Traumatology and Orthopedics Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghaiChina Center of Rehabilitation Medicine Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghaiChina Engineering Research Center of Traditional Chinese Medicine Intelligent Rehabilitation Ministry of EducationShanghaiChina

Electroacupuncture(EA)has been widely used for functional restoration after ***,its role in post-stroke rehabilitation and the associated regulatory mechanisms remain poorly *** this study,we applied EA to the Zusanli(ST36)and Quchi(LI11)acupoints in rats with middle cerebral artery occlusion and *** found that EA effectively increased the expression of brain-derived neurotrophic factor and its receptor tyrosine kinase B,synapsin-1,postsynaptic dense protein 95,and microtubule-associated protein 2 in the ischemic penumbra of rats with middle cerebral artery occlusion and ***,EA greatly reduced the expression of myelin-related inhibitors Nogo-A and NgR in the ischemic *** kinase B inhibitor ANA-12 weakened the therapeutic effects of *** findings suggest that EA can improve neurological function after middle cerebral artery occlusion and reperfusion,possibly through regulating the activity of the brain-derived neurotrophic factor/tyrosine kinase B signal *** procedures and experiments were approved by the Animal Research Committee of Shanghai University of Traditional Chinese Medicine,China(approval ***200110002)on January 10,2020.

关键词： brain-derived neurotrophic factor dendritic electroacupuncture ischemia/reperfusion motor function neurite outgrowth inhibitor-A neurological outcomes Nogo receptor synapse tyrosine kinase B

Local magnetic moment oscillation around an Anderson impurity on graphene

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 192-201页

作者： Shuai Li zhen ma Jin-Hua Gao School of Science Hebei University of Science and Technology School of Electronics and Information Zhengzhou University of Light Industry School of Physics and Wuhan National High magnetic Field Center Huazhong University of Science and Technology

We theoretically investigate the spin resolved Friedel oscillation （FO） and quasiparticle interference （QPI） in graphene induced by an Anderson *** the impurity becomes magnetic,the resulted FO becomes spin dependent,which gives rise to a local magnetic moment oscillation with an envelop decaying as r-2in real space in the doping ***,at half filling,the electron density and local magnetic moment will not oscillate but decay as *** spin resolved FO has both sublattice and spin ***,the local magnetic moment decay at half filling only occurs at one sublattice of graphene,which is quite like the phenomenon observed in the STM experiment (***ález-Herrero et al.,Science 352,437 （2016）).We further give an analytic formula about such spin dependent FO based on the stationary phase ***,we study the interference of quasiparticles around the magnetic impurity by calculating the spin dependent Fourier-transformed local density of states （FT-LDOS）.Our work gives a comprehensive understanding about the local magnetic moment oscillation around an Anderson impurity on graphene.

关键词： Friedel oscillation local magnetic moment graphene Anderson impurity

Integration of Electrical Properties and Polarization Loss Modulation on Atomic Fe–N‑RGO for Boosting Electromagnetic Wave Absorption

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Nano-Micro Letters 2025年第2期17卷 517-532页

作者： Kaili Zhang Yuefeng Yan zhen Wang Guansheng ma Dechang Jia Xiaoxiao Huang Yu Zhou State Key Laboratory of Precision Welding&Joining of materials and Structures Harbin Institute of TechnologyHarbin 150001People’s Republic of China School of materials Science and Engineering Harbin Institute of TechnologyHarbin 150001People’s Republic of China MIIT Key Laboratory of Advanced Structural‑Functional Integration materials&Green manufacturing Technology Harbin Institute of TechnologyHarbin 150001People’s Republic of China

Developing effective strategies to regulate graphene’s conduction loss and polarization has become a key to expanding its application in the electromagnetic wave absorption(EMWA)*** on the unique energy band structure of graphene,regulating its bandgap and electrical properties by introducing heteroatoms is considered a feasible ***,metal-nitrogen doping reduced graphene oxide(M–N-RGO)was prepared by embedding a series of single metal atoms M–N_(4) sites(M=Mn,Fe,Co,Ni,Cu,Zn,Nb,Cd,and Sn)in RGO using an N-coordination atom-assisted *** composites had adjustable conductivity and polarization to optimize dielectric loss and impedance matching for efficient EMWA *** results showed that the minimum reflection loss(RL_(min))of Fe–N-RGO reaches−74.05 dB(2.0 mm)and the maximum effective absorption bandwidth(EAB_(max))is 7.05 GHz(1.89 mm)even with a low filler loading of only 1 wt%.Combined with X-ray absorption spectra(XAFS),atomic force microscopy,and density functional theory calculation analysis,the Fe–N_(4) can be used as the polarization center to increase dipole polarization,interface polarization and defect-induced polarization due to d-p orbital hybridization and structural ***,electron migration within the Fe further leads to conduction loss,thereby synergistically promoting energy *** study demonstrates the effectiveness of metal-nitrogen doping in regulating the graphene′s dielectric properties,which provides an important basis for further investigation of the loss mechanism.

关键词： Electromagnetic wave absorption Fe-N-RGO Dipole polarization Conduction loss Impedance matching

Exosomes:the next-generation therapeutic platform for ischemic stroke

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Neural Regeneration Research 2025年第5期20卷 1221-1235页

作者： Wenjing Yin Hongyin ma Yang Qu Jiaxin Ren Yingying Sun zhen-Ni Guo Yi Yang Stroke Center Department of NeurologyFirst Hospital of Jilin UniversityChangchunJilin ProvinceChina Neuroscience Research Center Department of NeurologyFirst Hospital of Jilin UniversityChangchunJilin ProvinceChina

Current therapeutic strategies for ischemic stroke fall short of the desired objective of neurological functional ***,there is an urgent need to develop new methods for the treatment of this *** are natural cell-derived vesicles that mediate signal transduction between cells under physiological and pathological *** have low immunogenicity,good stability,high delivery efficiency,and the ability to cross the blood–brain *** physiological properties of exosomes have the potential to lead to new breakthroughs in the treatment of ischemic *** rapid development of nanotechnology has advanced the application of engineered exosomes,which can effectively improve targeting ability,enhance therapeutic efficacy,and minimize the dosages *** in technology have also driven clinical translational research on *** this review,we describe the therapeutic effects of exosomes and their positive roles in current treatment strategies for ischemic stroke,including their antiinflammation,anti-apoptosis,autophagy-regulation,angiogenesis,neurogenesis,and glial scar formation reduction ***,it is worth noting that,despite their significant therapeutic potential,there remains a dearth of standardized characterization methods and efficient isolation techniques capable of producing highly purified *** optimization strategies should prioritize the exploration of suitable isolation techniques and the establishment of unified workflows to effectively harness exosomes for diagnostic or therapeutic applications in ischemic ***,our review aims to summarize our understanding of exosome-based treatment prospects in ischemic stroke and foster innovative ideas for the development of exosome-based therapies.

关键词： blood–brain barrier electroacupuncture engineering exercise exosomes ischemic stroke mesenchymal stem cells microglia neuroprotection stents

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基于粗糙集算法的DDoS攻击威胁评估

通信技术 2017年第1期50卷 109-115页

作者：宋全振陈秀真马进上海交通大学信息安全工程学院上海200240

DDoS攻击具有发起容易、防御难的特点,一直是网络安全防御的难点和热点之一。针对常见的洪水式DDoS攻击,提出基于粗糙集理论的安全评估方法,实现安全威胁的实时定量评估。该方法通过测量攻击发起前后相关的网络和系统指标变化,确定用于... 详细信息

DDoS攻击具有发起容易、防御难的特点,一直是网络安全防御的难点和热点之一。针对常见的洪水式DDoS攻击,提出基于粗糙集理论的安全评估方法,实现安全威胁的实时定量评估。该方法通过测量攻击发起前后相关的网络和系统指标变化,确定用于衡量DDoS攻击影响的一系列指标。然后,进一步利用粗糙集算法分析DDoS安全威胁程度的样本决策表,计算属性重要性并进行归一化处理,得出各指标的权重。最后,对约简后的指标进行加权求和,得到安全态势值。实验证明,该方法能够有效地量化攻击发生前后的系统安全状态变化。与现有的安全评估方法相比,利用粗糙集理论的安全评估方法可以在不依赖先验知识的前提下确定指标权重,客观地对DDoS攻击做出评估和预测。

关键词： DDoS 安全评估粗糙集算法态势感知

动态心电图评价冠状动脉粥样硬化性心脏病患者左心房容积、功能和同步性的价值研究

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中国现代医学杂志 2020年第10期30卷 121-124页

作者：陈郧马珍珍张威邓瑞国药东风总医院(湖北医药学院附属东风医院)心电图室湖北十堰442001

目的探讨动态心电图(AECD)评价冠状动脉粥样硬化性心脏病(以下简称冠心病)患者左心房容积、功能和同步性的价值。方法选取2016年8月—2018年2月在国药东风总医院心内科诊治的72例冠心病患者作为观察组,选取同期该院经冠状动脉造影检测... 详细信息

目的探讨动态心电图(AECD)评价冠状动脉粥样硬化性心脏病(以下简称冠心病)患者左心房容积、功能和同步性的价值。方法选取2016年8月—2018年2月在国药东风总医院心内科诊治的72例冠心病患者作为观察组,选取同期该院经冠状动脉造影检测证实冠状动脉狭窄率0.05)。观察组左心房最大容积、左心房最小容量及左心房容积值高于对照组(P0.05)。结论AECD可早期准确评价冠心病患者左心房容积、功能和同步性,对于冠心病的临床诊断及其预后、疗效评估具有临床指导意义。

关键词：心脏病心房功能,左心电描记术,便携式诊断设备

FDNet: Fourier transform guided dual-channel underwater image enhancement diffusion network

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Science China Technological Sciences 2025年第1期 62-78页

作者： zhen ZHU Xiaobo LI Qianwen ma Jingsheng ZHAI Haofeng HU School of marine Science and Technology Tianjin University College of Mechanical Engineering and Automation Fuzhou University

Due to the scattering and absorption of light, underwater imaging yields suboptimal results characterized by low brightness, diminished image contrast, and the loss of details. Current learning-based underwater image enhancement(UIE)methods mainly focus on addressing these issues in the spatial domain, with limited attention to the Fourier frequency *** propose the Fourier transform guided dual-channel underwater image enhancement diffusion network(FDNet), aiming to fully leverage frequency domain information and the characteristics of a diffusion-based generation model. The amplitude-phase dualchannel not only effectively provides feedback on the energy distribution of the image but also incorporates crucial image structure and texture information. Capitalizing on these advantages, we first introduce a Fourier transform-based amplitude-phase dualchannel enhancement front-end network for UIE. This network significantly improves the quality of the network's image input,including brightness and contrast, by incorporating phase congruency edge enhancement and prior-driven amplitude mapping strategies. The preceding network mitigates the overall training challenges caused by poor input image quality. Simultaneously,the application of denoising networks based on lightweight transformers effectively improves the computational time required for each iteration during model training. The results indicate that FDNet outperforms many current learning-based UIE algorithms in restoring images across multiple real underwater image datasets, demonstrating more robust generalization capabilities in degraded underwater scenarios. The competitive performance advantage achieved in enhancing visual quality underscores the effectiveness of our method.

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中国革命传统作品的教育价值及其教学实现——以高中语文教学为例

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教师教育学报 2025年第1期12卷 85-96页

作者：王珍马绍玺云南师范大学教育学部云南昆明650500 安徽省太和中学安徽阜阳236600

中国革命传统作品蕴含独特的教育价值,但在实际的语文教学中并未得到应有的重视。为有效实现和充分彰显中国革命传统作品的教育价值,语文教师在进行相关教学时,应以习近平新时代中国特色社会主义思想为指导,以《革命传统进中小学课程教... 详细信息

中国革命传统作品蕴含独特的教育价值,但在实际的语文教学中并未得到应有的重视。为有效实现和充分彰显中国革命传统作品的教育价值,语文教师在进行相关教学时,应以习近平新时代中国特色社会主义思想为指导,以《革命传统进中小学课程教材指南》为指引,以《普通高中语文课程标准(2017年版2020年修订)》为方向,以统编高中语文教材为依托,以当下高中语文教学现状为问题导向,从德育价值、美育价值、史学价值、文化价值四个维度深入挖掘中国革命传统作品的教育潜力。中国革命传统作品教育价值的四个维度具有整体性、层次性、交互性和生成性,彼此之间存在着相互联系、相互依存和相互生成的结构关系,共同形成中国革命传统作品巨大的教育潜力。教师可通过巧妙整合文本资源、精心创设教学情境、有序组织实践活动,最大化实现中国革命传统作品的教育价值,增强学生对中国革命传统作品的价值认同,使之能够赓续红色血脉、践行革命精神,最终成长为德智体美劳全面发展的社会主义建设者和接班人。

关键词：立德树人教育价值中国革命传统作品统编高中语文教材教学路径