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Journal of Modern Power Systems and Clean Energy 2024年第3期12卷 958-970页

作者： Jialiang wu zhen Wang Ruixu Liu yu Shan Chenxuan Wang the College of Electrical Engineering Zhejiang UniversityHangzhou 310027China the Economic Research Institute of State Grid Zhejiang Electric Power Co. Ltd.Hangzhou 310016China

Hybrid multi-terminal direct current(MTDC)transmission technology has been a research focus,and primary frequency regulation(FR)improvement in the receiving-end system is one of the problems to be *** paper presents a decentralized primary FR scheme for hybrid MTDC power systems considering multi-source enhancement to help suppress frequency disturbance in the receiving-end *** the converters only need local frequency or DC voltage signal input to respond to system disturbance without communication or a control center,i.e.,a decentralized control *** proposed scheme can activate appropriate power sources to assist in FR in various system disturbance severities with fine-designed thresholds,ensuring sufficient utilization of each power *** better balance FR performance and FR resource participation,an evaluation index is proposed and the parameter optimization problem is further ***,the validity of the proposed scheme is verified by simulations in MATLAB/Simulink.

关键词： Decentralized control scheme primary frequency regulation(FR) rate of change of frequency(ROCOF) system frequency disturbance

Diagnostic value of conventional endoscopic ultrasound for lymph node metastasis in upper gastrointestinal neoplasia:A metaanalysis

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World Journal of Gastroenterology 2023年第30期29卷 4685-4700页

作者： Cong Chen Ya-Lan Song zhen-yu wu Jing Chen Yao Zhang Lei Chen Institute of Gastroenterology Southwest HospitalArmy Medical University(Third Military Medical University)Chongqing 400038China Department of Epidemiology College of Preventive MedicineArmy Medical University(Third Military Medical University)Chongqing 400038China

BACKGROUND Upper gastrointestinal neoplasia mainly includes esophageal cancer and gastric cancer,both of which have high morbidity and *** node metastasis(LNM),as the most common metastasis mode of both diseases,is an important factor affecting tumor stage,treatment strategy and clinical *** a new fusion technology,endoscopic ultrasound(EUS)is becoming increasingly used in the diagnosis and treatment of digestive system diseases,but its use in detecting LNM in clinical practice remains *** To evaluate the diagnostic value of conventional EUS for LNM in upper gastrointestinal *** Using the search mode of“MeSH+Entry Terms”and according to the predetermined inclusion and exclusion criteria,we conducted a comprehensive search and screening of the PubMed,EMBASE and Cochrane Library databases from January 1,2000 to October 1,*** data were extracted according to the predetermined data extraction *** quality of the included studies was assessed using the Quality Assessment of Diagnostic Accuracy Studies tool,and the results of the quality assessment were presented using Review Manager 5.3.5 ***,Stata14.0 software was used for a series of statistical *** A total of 22 studies were included in our study,including 2986 *** pooled sensitivity,specificity,positive likelihood ratio,negative likelihood ratio,diagnostic score and diagnostic odds ratio of conventional EUS in the diagnosis of upper gastrointestinal neoplasia LNM were 0.62[95%confidence interval(CI):0.50-0.73],0.80(95%CI:0.73-0.86),3.15(95%CI:2.46-4.03),0.47(95%CI:0.36-0.61),1.90(95%CI:1.51-2.29)and 6.67(95%CI:4.52-9.84),*** area under the summary receiver operating characteristic curve was 0.80(95%CI:0.76-0.83).Sensitivity analysis indicated that the results of the meta-analysis were *** was considerable heterogeneity among the included studies,and the threshold effect was an important source of heterogenei

关键词： Endosonography Esophageal neoplasms Stomach neoplasms Lymphatic metastasis Diagnosis Meta-analysis

Track-Pattern-Based Characteristics of Extratropical Transitioning Tropical Cyclones in the Western North Pacific

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Advances in Atmospheric Sciences 2024年第6期41卷 1251-1263页

作者： Hong HUANG Dan wu yuan WANG zhen WANG yu LIU College of Meteorology and Oceanography National University of Defense TechnologyChangsha 410000China No.31631 Army of PLA Huizhou 516000China School of Atmospheric Sciences and Key Laboratory of Mesoscale Severe Weather/Ministry of Education Nanjing 210023China No.93721 Army of PLA Shuozhou 038300China

Based on the Regional Specialized Meteorological Center(RSMC)Tokyo-Typhoon Center best-track data and the NCEP-NCAR reanalysis dataset,extratropical transitioning(ET)tropical cyclones(ETCs)over the western North Pacific(WNP)during 1951–2021 are classified into six clusters using the fuzzy c-means clustering method(FCM)according to their track *** characteristics of the six hard-clustered ETCs with the highest membership coefficient are *** tropical cyclones(TCs)that were assigned to clusters C2,C5,and C6 made landfall over eastern Asian countries,which severely threatened these *** landfalling TCs,93.2%completed their ET after landfall,whereas 39.8%of ETCs completed their transition within one *** frequency of ETCs over the WNP has decreased in the past four decades,wherein cluster C5 demonstrated a significant decrease on both interannual and interdecadal timescales with the expansion and intensification of the western Pacific subtropical high(WPSH).This large-scale circulation pattern is favorable for C2 and causes it to become the dominant track pattern,owning to it containing the largest number of intensifying ETCs among the six clusters,a number that has increased insignificantly over the past four *** surface roughness variation and three-dimensional background circulation led to C5 containing the maximum number of landfalling TCs and a minimum number of intensifying *** results will facilitate a better understanding of the spatiotemporal distributions of ET events and associated environment background fields,which will benefit the effective monitoring of these events over the WNP.

关键词： Western North Pacific tropical cyclone extratropical transition fuzzy c-means clustering method

Configuring single-layer MXene nanosheet onto natural wood fiber via C-Ti-C covalent bonds for high-stability Li-S batteries

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Journal of Energy Chemistry 2024年第8期95卷 701-711,I0016页

作者： Yangyang Chen yu Liao Ying wu Lei Li zhen Zhang Sha Luo Yiqiang wu Yan Qing College of Materials Science and Technology Central South University of Forestry and TechnologyChangsha 410004HunanChina

Lithium-sulfur batteries(LSBs)are considered promising candidates for next-generation battery technologies owing to their outstanding theoretical energy density and ***,the low conductivity and polysulfide shuttling effect of S cathodes severely hamper the practical performance of ***,in situ-generated single layer MXene nanosheet/hierarchical porous carbonized wood fiber(MX/PCWF)composites are prepared via a nonhazardous eutectic activation strategy coupled with pyrolysis-induced gas *** unique architecture,wherein single layer MXene nanosheets are constructed on carbonized wood fiber walls,ensures rapid polysulfide conversion and continuous electron transfer for redox *** C-Ti-C bonds formed between MXene and PCWF can considerably expedite the conversion of polysulfides,effectively suppressing the shuttle *** impressive capacity of 1301.1 m A h g^(-1)at 0.5 C accompanied by remarkable stability is attained with the MX/PCWF host,as evidenced by the capacity maintenance of 722.6 m A h g^(-1)after 500 ***,the MX/PCWF/S cathode can still deliver a high capacity of 886.8 m A h g^(-1)at a high S loading of 5.6 mg cm^(-2).The construction of two-dimensional MXenes on natural wood fiber walls offers a competitive edge over S-based cathode materials and demonstrates a novel strategy for developing high-performance batteries.

关键词： Lithium-sulfur batteries S cathodes MXene nanosheets Wood fiber C-Ti-C bonds

SPNS1 ablation drives skeletal muscle atrophy by disrupting mitophagy,mitochondrial function,and apoptosis in mice

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Genes & Diseases 2024年第5期11卷 25-28页

作者： Xianzhong Zhang Fengmin Zhang Haofan wu zhen yu Chengle Zhuang Department of Gastrointestinal Surgery Shanghai Tenth People's HospitalSchool of MedicineTongji UniversityShanghai200092China Colorectal Cancer Center Shanghai Tenth People's HospitalSchool of MedicineTongji UniversityShanghai 200072China

Sarcopenia is characterized by a dramatic decline in muscle mass and function during aging,which of ten leads to reduced mobility,diminished quality of life,and shortened *** recent advances in sarcopenia,the mechanisms that mediate skeletal muscle dysfunction remain unclear.1 Lysosomal plays a vital role in digesting and recycling macromolecules,and several studies have shown that lysosomal acidification and autophagy decrease with age,which may impair the clearance of damaged mitochondria.

关键词： skeletal function spite

Climatic impacts induced by winter wheat irrigation over North China simulated by the nonhydrostatic RegCM4.7

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Advances in Climate Change Research 2024年第2期15卷 197-210页

作者： Jia wu zhen-yu HAN Xue-Jie GAO zheng-Jia LIU National Climate Centre China Meteorological AdministrationBeijing 100081China Key Laboratory for Climate Studies China Meteorological AdministrationBeijing 100081China Climate Change Research Center Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters Nanjing University of Information Science and TechnologyNanjing 210044China Institute of Geographic Sciences and Natural Resources Research Chinese Academy of SciencesBeijing 100101China

Quantification of the impact of winter wheat irrigation on the climate and the occurrence of extreme climatic events over North China is crucial for regional adaptation *** related studies mainly focused on the impact on surface processes;however,few focused on the effects of extreme events using high-resolution nonhydrostatic regional climate ***,the 9-km-resolution nonhydrostatic RegCM4.7 was coupled with a crop irrigation scheme and an updated winter wheat irrigation dataset to better simulate irrigation *** experiments were conducted with and without winter wheat irrigation to isolate the effects of *** showed that irrigation simulation reduces the model biases in temperature,precipitation,latent heat flux,soil moisture,sensitive heat flux,and top-layer soil ***,it also reduces the bias and increases the correlation with observations obtained in irrigated areas,especially in summer,indicating better representation of irrigation *** wheat irrigation tends to cause substantial cooling of the local surface maximum,minimum,and mean air temperatures(by-1.68,-0.34,and-0.79℃,respectively)over irrigated areas of North China,with the largest changes observed in relation to maximum ***,precipitation is found to increase during spring and summer,which is strongly related to water vapor transport in the lower levels of the *** analyses indicated that the number of annual mean hot days decrease(-13.9 d),whereas the number of both comfort days(+10.2 d)and rainy days(days with total precipitation greater than 1 mm:+6.6 d)increase over irrigated areas,demonstrating beneficial feedback to human perception and ***,although the heat wave risk increases(number of annual mean heat wave days:+5.8 d),the impact is limited to small areas within irrigated ***,no notable change was found in terms of heavy rainfall events and precipitation intensity

关键词： Nonhydrostatic regional climate model Irrigation effect Extreme events North China

Highly Aligned Graphene Aerogels for Multifunctional Composites

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Nano-Micro Letters 2024年第6期16卷 276-342页

作者： Ying wu Chao An Yaru Guo Yangyang Zong Naisheng Jiang Qingbin zheng Zhong‑zhen yu Beijing Advanced Innovation Center for Materials Genome Engineering School of Materials Science and EngineeringUniversity of Science and Technology BeijingBeijing 100083People’s Republic of China Institute of Materials Intelligent Technology Liaoning Academy of MaterialsShenyang 110004People’s Republic of China School of Science and Engineering The Chinese University of Hong KongShenzhenShenzhenGuangdong 518172People’s Republic of China State Key Laboratory of Organic‑Inorganic Composites College of Materials Science and EngineeringBeijing University of Chemical TechnologyBeijing 100029People’s Republic of China

Stemming from the unique in-plane honeycomb lattice structure and the sp^(2)hybridized carbon atoms bonded by exceptionally strong carbon–carbon bonds,graphene exhibits remarkable anisotropic electrical,mechanical,and thermal *** maximize the utilization of graphene’s in-plane properties,pre-constructed and aligned structures,such as oriented aerogels,films,and fibers,have been *** unique combination of aligned structure,high surface area,excellent electrical conductivity,mechanical stability,thermal conductivity,and porous nature of highly aligned graphene aerogels allows for tailored and enhanced performance in specific directions,enabling advancements in diverse *** review provides a comprehensive overview of recent advances in highly aligned graphene aerogels and their *** highlights the fabrication methods of aligned graphene aerogels and the optimization of alignment which can be estimated both qualitatively and *** oriented scaffolds endow graphene aerogels and their composites with anisotropic properties,showing enhanced electrical,mechanical,and thermal properties along the alignment at the sacrifice of the perpendicular *** review showcases remarkable properties and applications of aligned graphene aerogels and their composites,such as their suitability for electronics,environmental applications,thermal management,and energy *** and potential opportunities are proposed to offer new insights into prospects of this material.

关键词： Highly aligned graphene aerogels Quantitative characterization of alignment Multifunctional composites Anisotropic properties Multifunctional applications

Molecular typing of familial temporal lobe epilepsy

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World Journal of Psychiatry 2022年第1期12卷 98-107页

作者： Chao Liu Xiao-Zhi Qiao Zi-Han Wei Mi Cao zhen-yu wu Yan-Chun Deng Department of Neurology The First Affiliated Hospital of Air Force Medical UniversityXi'an 710032Shaanxi ProvinceChina Department of Anatomy Histology and Embryology and K.K.Leung Brain Research CentreSchool of Basic MedicineAir Force Medical UniversityXi'an 710032Shaanxi ProvinceChina

The pathogenesis of temporal lobe epilepsy(TLE)was originally considered to be ***,some reports showed that TLE was clustered in some families,indicating a genetic *** the popularity of genetic testing technology,eleven different types of familial TLE(FTLE),including ETL1-ETL11,have been reported,of which ETL9-ETL11 had not yet been included in the OMIM *** types of FTLE were caused by different genes/Loci and had distinct ***1,ETL7 and ETL10 were characterized by auditory,visual and aphasia seizures,leading to the diagnosis of familial lateral ***2,ETL3 and ETL6 showed prominent autonomic symptom and automatism with or without hippocampal abnormalities,indicating a mesial temporal *** seizures were common in FTLEs such as ETL2,ETL5,ETL6 and ***4 was diagnosed as occipitotemporal lobe epilepsy with a high incidence of migraine and visual *** the diversity and complexity of the symptoms of TLE,neurologists enquiring about the family history of epilepsy should ask whether the relatives of the proband had experienced unnoticeable seizures and whether there is a family history of other neurological diseases *** FTLE patients had a good prognosis with or without anti-seizure medication treatment,with the exception of patients with heterozygous mutations of the CPA6 *** pathogenic mechanism was diverse among these genes and spans disturbances of neuron development,differentiation and synaptic *** this article,we describe the research progress on eleven different types of *** precise molecular typing of FTLE would facilitate the diagnosis and treatment of FTLE and genetic counseling for this disorder.

关键词： Temporal lobe epilepsy Gene mutation Gene locus Phenotypes Prognosis

Recent progress in self-propelled particles

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Journal of Hydrodynamics 2024年第1期36卷 61-77页

作者： zhen-yu Ouyang Jian-zhong Lin Laboratory of Impact and Safety Engineering Ministry of EducationNingbo UniversityNingbo315201China Department of Mechanics State Key Laboratory of Fluid Power and Mechatronic SystemsZhejiang UniversityHangzhou310027China

Self-propelled particles are commonly found in a large number of planktonic organisms such as bacteria,fungi,and algae in nature,and researchers have taken a long interest in exploring their swimming mechanisms for more than a *** in the past 20 years,with the development of computational fluid dynamics and flow display technology,as well as the need for the design of synthetic self-propelled particles and micro-swimming devices,self-propelled particles have become the forefront and hotspot of current research in the field of fluid *** paper first introduces the swimming characteristics of common self-propelled particles,leading to a classic“squirmer”type self-propelled particle *** this basis,a systematic introduction and summary of the theoretical and numerical simulation research of“squirmer”will be ***,the main challenges and opportunities faced by the current research will be summarized.

关键词： Self-propelled particles multiphase flow hydrodynamic interaction

Patient-derived induced pluripotent stem cells with a MERTK mutation exhibit cell junction abnormalities and aberrant cellular differentiation potential

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World Journal of Stem Cells 2024年第5期16卷 512-524页

作者： Hang Zhang Ling-Zi wu zhen-yu Liu Zi-Bing Jin Beijing Institute of Ophthalmology Beijing Tongren Eye CenterBeijing Tongren HospitalCapital Medical UniversityBeijing 100730China

BACKGROUND Human induced pluripotent stem cell(hiPSC)technology is a valuable tool for generating patient-specific stem cells,facilitating disease modeling,and invest-igating disease ***,iPSCs carrying specific mutations may limit their clinical applications due to certain inherent *** To investigate the impact of MERTK mutations on hiPSCs and determine whether hiPSC-derived extracellular vesicles(EVs)influence anomalous cell junction and differentiation *** We employed a non-integrating reprogramming technique to generate peripheral blood-derived hiPSCs with and hiPSCs without a MERTK ***-somal karyotype analysis,flow cytometry,and immunofluorescent staining were utilized for hiPSC *** and proteomics were employed to elucidate the expression patterns associated with cell junction abnormalities and cellular differentiation ***,EVs were isolated from the supernatant,and their RNA and protein cargos were examined to investigate the involvement of hiPSC-derived EVs in stem cell junction and *** The generated hiPSCs,both with and without a MERTK mutation,exhibited normal karyotype and expressed pluripotency markers;however,hiPSCs with a MERTK mutation demonstrated anomalous adhesion capability and differentiation potential,as confirmed by transcriptomic and proteomic ***,hiPSC-derived EVs were involved in various biological processes,including cell junction and *** HiPSCs with a MERTK mutation displayed altered junction characteristics and aberrant differentiation ***,hiPSC-derived EVs played a regulatory role in various biological processes,including cell junction and differentiation.

关键词： Cell junction Cellular differentiation Extracellular vesicle Human induced pluripotent stem cells Transcriptomics Proteomics