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Widespread infection and diverse infection patterns of Wolbachia in Chinese aphids

Insect Science 2014年第3期21卷 313-325页

作者： zhe Wang Xiao-Min su Juan Wen Li-Yun Jiang Ge-Xia Qiao Key Laboratory of Zoological Systematics and Evolution Institute of Zoology Chinese Academy of Sciences University of Chinese Academy of Sciences Beijing China

Wolbachia are intracellular symbionts that infect a wide range of arthropods and filarial nematodes. Aphids are engaged in diverse and complex relationships withtheir endosymbionts. Four supergroups （A, B, M and N） of Wolbachia were previously detected in aphids and supergroups M and N were only found in aphids. In this study, wedetected and described Wolbachia infections in natural populations of aphids in China. Three supergroups （A, B and M） were found in the examined aphid species. supergroupM was preponderant, whereas supergroups A and B were only detected in certain species. supergroup N was not found in this study. There were four infection patterns of Wolbachiain aphids, namely, infection with supergroup M alone, co-infection with supergroups A and M, co-infection with supergroups B and M, and co-infection with supergroups A, Band M. The pattern of infection only with supergroup M was universal and was tbund in all evaluated subfamilies. Only two subfamilies, Aphidinae and Lachninae, manifestedto present all four infection patterns. Three patterns were observed in Calaphidinae （M, A＆M, B＆M） and Eriosomatinae （M, B＆M, A＆B＆M）. Two patterns were observed inthe Anoeciinae （M, A＆M） and Greenideinae （M, B＆M）, and only one pattern （M） was observed in the remaining families and/or subfamilies of Aphidoidea. These results indi-cated that Wolbachia infections in Chinese aphids are widespread. Phylogenetic analyses suggest that Wolbachia supergroup M spread rapidly and recently among all host speciesof aphids in China. Reasons for this spread and its mechanisms are discussed along with the possible effects of Wolbachia on their aphid hosts.

关键词： aphid characterization detection infection pattern prevalence Wolbachia

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Ultrafine Vacancy-Rich Nb_(2)O_(5)Semiconductors Confined in Carbon Nanosheets Boost Dielectric Polarization for High-Attenuation Microwave Absorption

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Nano-Micro Letters 2023年第10期15卷 478-493页

作者： zhe su Shan Yi Wanyu Zhang Xiaxi Xu Yayun Zhang Shenghu Zhou Bo Niu Donghui Long Shanghai Key Laboratory of Multiphase Materials Chemical Engineering School of Chemical EngineeringEast China University of Science and TechnologyShanghai 200237People’s Republic of China Key Laboratory for Specially Functional Materials and Related Technology of the Ministry of Education East China University of Science and TechnologyShanghai 200237People’s Republic of China

The integration of nano-semiconductors into electromagnetic wave absorption materials is a highly desirable strategy for intensifying dielectric polarization loss;achieving high-attenuation microwave absorption and realizing in-depth comprehension of dielectric loss mechanisms remain ***,ultrafine oxygen vacancy-rich Nb_(2)O_(5)semiconductors are confined in carbon nanosheets(ov-Nb_(2)O_(5)/CNS)to boost dielectric polarization and achieve high *** polarization relaxation,electromagnetic response,and impedance matching of the ov-Nb_(2)O_(5)/CNS are significantly facilitated by the Nb_(2)O_(5)semiconductors with rich oxygen vacancies,which consequently realizes an extremely high attenuation performance of-80.8 dB(>99.999999%wave absorption)at 2.76 *** a dielectric polarization center,abundant Nb_(2)O_(5)–carbon heterointerfaces can intensify interfacial polarization loss to strengthen dielectric polarization,and the presence of oxygen vacancies endows Nb_(2)O_(5)semiconductors with abundant charge separation sites to reinforce electric dipole ***,the three-dimensional reconstruction of the absorber using microcomputer tomography technology provides insight into the intensification of the unique lamellar morphology regarding multiple reflection and scattering dissipation ***,ov-Nb_(2)O_(5)/CNS demonstrates excellent application potential by curing into a microwave-absorbing,machinable,and heat-dissipating *** work provides insight into the dielectric polarization loss mechanisms of nano-semiconductor/carbon composites and inspires the design of high-performance microwave absorption materials.

关键词： Electromagnetic wave absorption Nb_(2)O_(5)semiconductor Dielectric polarization loss Oxygen vacancy Nb_(2)O_(5)-carbon hetero-interface

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Guarding Legal Communication with Smart Jammer:Stackelberg Game Based Power Control Analysis

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China Communications 2021年第4期18卷 126-136页

作者： zhe su Nan Qi Yongjie Yan Zhiyong Du Jiaxin Chen Zhibin Feng Qihui Wu College of Electronic and Information Engineering Nanjing University of Aeronautics and AstronauticsNanjing 211106China State Key Laboratory of Air Traffic Management System and Technology Nanjing 210014China th Research Institute of China Electronics Technology Group Corporation Nanjing 210007China College of Information and Communication National University of Defense TechnologyChangsha 430010China College of Communications Engineering Army Engineering University of PLANanjing 210000China

This paper investigates a power control problem in a jamming system,where a separate smart jammer is deployed to ensure the communication security of the legal ***,due to power leakage,the smart jammer may incur unintentional interference to legal *** key is how to suppress illegal communication while limit the negative impact on legal user.A jamming counter measure Stackelberg game is formulated to model the jamming power control dynamic of the *** smart jammer acts as a leader to sense and interfere illegal communications of the illegal user,while the illegal user acts as a *** the game,the impact of uncertain channel information is taken into *** to whether illegal user considers the uncertain channel information,we investigate two scenarios,namely,illegal user can obtain statistical distribution and accurate information of interference channel gain and its own cost,*** work not only proposes a jamming counter measure iterative algorithm to update parameters,but also gives two solutions to obtain the Stackelberg equilibrium(SE).The power convergence behaviours under two scenarios are analyzed and ***,brute force is used to verify the accuracy of the SE value further.

关键词： power control jamming communication Received:Apr.13,2020 Revised:Sep.01,2020 Editor:Haifeng zheng systems Stackelberg game

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Potential use of a dried saliva spot(DSS)in therapeutic drug monitoring and disease diagnosis

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Journal of Pharmaceutical Analysis 2022年第6期12卷 815-823页

作者： Yu Han Xi-Ling Li Minghui Zhang Jing Wang su Zeng Jun zhe Min Key Laboratory of Natural Medicines of the Changbai Mountain Ministry of EducationDepartment of Pharmaceutical AnalysisCollege of PharmacyYanbian UniversityYanjiJilin133002China Institute of Drug Metabolism and Pharmaceutical Analysis Zhejiang Province Key Laboratory of Anti-Cancer Drug ResearchCollege of Pharmaceutical SciencesZhejiang UniversityHangzhou310058China

In recent years,scientific researchers have increasingly become interested in noninvasive sampling methods for therapeutic drug monitoring and disease *** a result,dried saliva spot(DSS),which is a sampling technique for collecting dried saliva samples,has been widely used as an alternative matrix to serum for the detection of target *** the DSS method with a highly sensitive detection instrument improves the efficiency of the preparation and analysis of biological ***,dried blood spots,dried plasma spots,and dried matrix spots,which are similar to those of the DSS method,are *** with alternative biological fluids used in dried spot methods,including serum,tears,urine,and plasma,saliva has the advantage of convenience in terms of sample collection from children or persons with *** review aims to provide integral strategies and guidelines for dried spot methods to analyze biological samples by illustrating several dried spot ***,we summarize recent advancements in DSS methods from June 2014 to March 2021 and discuss the advantages and disadvantages of the key aspects of this method,including sample preparation and method ***,we outline the challenges and prospects of such methods in practical applications.

关键词： Human saliva Dried saliva spot Therapeutic drug monitoring Disease diagnosis

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FT_(4)水平及FT_(4)/FT_(3),比值鉴别垂体性甲状腺功能减退和低T_(3)综合征的有效性研究

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中国实用内科杂志 2024年第8期44卷 670-674页

作者：杨彦娜徐子博田泽阳杨光苏婧如潘清蓉陈哲首都医科大学附属北京电力医院急诊科北京100552 首都医科大学附属北京朝阳医院教育处北京100020 天津医科大学天津300203 首都医科大学附属北京朝阳医院内分泌科北京100020

目的探索游离甲状腺素(FT_(4))水平及FT_(4)/游离三碘甲腺原氨酸(FT_(3))比值初步鉴别垂体性甲状腺功能减退(简称甲减)和低T_(3)综合征的有效性。方法收集2010年8月至2022年1月在北京朝阳医院住院的患者161例,其中垂体性甲减47例、低T_... 详细信息

目的探索游离甲状腺素(FT_(4))水平及FT_(4)/游离三碘甲腺原氨酸(FT_(3))比值初步鉴别垂体性甲状腺功能减退(简称甲减)和低T_(3)综合征的有效性。方法收集2010年8月至2022年1月在北京朝阳医院住院的患者161例,其中垂体性甲减47例、低T_(3)综合征65例、甲状腺功能正常者49例。对比3组患者的FT_(4)水平及FT_(4)/FT_(3),比值的差异,应用ROC曲线分析FT_(4)/FT_(3),比值初步鉴别垂体性甲减和低T_(3),综合征的有效性,并确定最佳临界值。结果当FT_(4)<0.82ng/dL和(或)FT_(4)/FT_(3),比值<0.45时,诊断垂体性甲减的可能性较大。结论FT_(4)水平、FT_(4)/FT_(3),比值可以初步鉴别垂体性甲减和低T_(3),综合征。

关键词： FT_(4)/FT_(3),比值垂体性甲状腺功能减退低T_(3)综合征

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Oxidation of Silicon and Boron in Boron Containing Molten Iron

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Journal of Iron and Steel Research International 2007年第6期14卷 32-36页

作者： YANG Zhong-dong LIU su-lan LI zhe-fu XUE Xiang-xin School of Materials and Metallurgy Northeastern University Shenyang 110004 Liaoning China

A new process of directly smelting boron steel from boron-containing pig iron has been established. The starting material boron-containing pig iron was obtained from ludwigite ore, which is very abundant in the eastern area of Liaoning Province of China. The experiment was performed in a medium frequency induction furnace, and Fe2O3 powder was used as the oxidizing agent. The effects of temperature, addition of Fe2O3, basicity, stirring, and composition of melt on the oxidation of silicon and boron were investigated respectively. The results showed that sili- con and boron were oxidized simultaneously and their oxidation ratio exceeded 90% at 1 400℃. The favorable oxidation temperature of silicon was about 1 300-- 1 350℃. High oxygen potential of slag and strong stirring enhanced the oxidation of silicon and boron.

关键词： boron-containing pig iron oxidation silicon boron

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Single-cell DNA methylome analysis of circulating tumor cells

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Chinese Journal of Cancer Research 2021年第3期33卷 391-404页

作者： Hengyu Chen zhe su Ruoyan Li Ning Zhang Hua Guo Fan Bai Biomedical Pioneering Innovation Center(BIOPIC) School of Life SciencesPeking UniversityBeijing 100871China Laboratory of Cancer Cell Biology Tianjin Medical University Cancer Institute and HospitalTianjin 300060China Translational Cancer Research Center First HospitalPeking UniversityBeijing 100871China

Objective: Previous investigations of circulating tumor cells(CTCs) have mainly focused on their genomic or transcriptomic features, leaving their epigenetic landscape relatively uncharacterized. Here, we investigated the genome-wide DNA methylome of CTCs with a view to understanding the epigenetic regulatory mechanisms underlying cancer ***: We evaluated single-cell DNA methylome and copy number alteration(CNA) in 196 single cells,including 107 CTCs collected from 17 cancer patients covering six different cancer types. Our single-cell bisulfite sequencing(sc BS-seq) covered on average 11.78% of all Cp G dinucleotides and accurately deduced the CNA patterns at 500 kb ***: We report distinct subclonal structures and different evolutionary histories of CTCs inferred from CNA and DNA methylation profiles. Furthermore, we demonstrate potential tumor origin classification based on the tissue-specific DNA methylation profiles of ***: Our work provides a comprehensive survey of genome-wide DNA methylome in single CTCs and reveals 5-methylcytosine(5-m C) heterogeneity in CTCs, addressing the potential epigenetic regulatory mechanisms underlying cancer metastasis and facilitating the future clinical application of CTCs.

关键词： Circulating tumor cells methylome copy number alteration

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广西少数民族学龄前儿童身心发展规律研究

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科学通报 2024年第24期69卷 3608-3616页

作者：颜志雄贺哲邹霞韩佳豪姜玲慧蓝子清蔡宇航冯蓉蓉苏学权侯晓晖李强南宁师范大学教育与发展人口神经科学研究基地南宁530001 广西幼儿师范高等专科学校学前儿童心理发展实验室南宁530008

按人口比例抽取样本、构建少数民族群体心理发展队列是未来大规模队列建设的重要方向.作为个体毕生发展的奠基阶段,学龄前儿童的心理发展对学业成就、情绪调控和社会适应产生深远影响.本研究构建广西少数民族学龄前儿童心理发展队列,揭... 详细信息

按人口比例抽取样本、构建少数民族群体心理发展队列是未来大规模队列建设的重要方向.作为个体毕生发展的奠基阶段,学龄前儿童的心理发展对学业成就、情绪调控和社会适应产生深远影响.本研究构建广西少数民族学龄前儿童心理发展队列,揭示12个少数民族聚居区学龄前儿童心理发展的特点规律.基于《学龄前儿童身心发展评估量表》,以在线方式采集132792名家长对学龄前儿童在探究与认知、社会性与情感、语言与交流、美感与表现和健康与体能等5个领域的发展数据.结果表明,学龄前儿童在探究与认知(median=4.03)、美感与表现(median=4.02)两个领域的发展高于社会性与情感(median=3.89)、语言与交流(median=3.81)和健康与体能(median=3.58);女孩在语言与交流(W=7.58×10^(7),P<0.001,Cliff’s delta=0.14)和美感与表现(W=6.55×10^(7),P<0.001,Cliff’s delta=0.16)领域的发展比男孩的水平高.健康与体能表现出显著的年级差异,小班幼儿健康与体能的发展优于中班和大班幼儿(H=4562.91,P<0.001,η^(2)=0.15);相比其他民族聚居区学龄前儿童,龙胜各族、大化瑶族和巴马瑶族的学龄前儿童身心发展水平相对较高.多个少数民族聚居区学龄前儿童身心发展存在性别差异.研究初步揭示了广西少数民族学龄前儿童身心发展的特点规律,为构建少数民族学龄前儿童脑智发育队列积累了前期基础,为制定契合少数民族学龄前儿童脑智发育特点的民族教育政策提供了数据支撑.

关键词：少数民族学龄前儿童身心发展脑智发育队列

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Uncertainty relations for triples of observables and the experimental demonstrations

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Science China(Physics,Mechanics & Astronomy) 2023年第5期66卷 97-105页

作者： Huang-Qiu-Chen Wang Bo Liu Yong-Nan sun Qi-Ping su zhe sun Xiaoguang Wang School of Physics Hangzhou Normal UniversityHangzhou 310036China School of Information and Electrical Engineering Hangzhou City UniversityHangzhou 310015China Key Laboratory of Optical Field Manipulation of zhejiang Province Department of PhysicsZhejiang Sci-Tech UniversityHangzhou 310018China

Uncertainty relations are of profound significance in quantum mechanics and quantum information *** well-known Heisenberg-Robertson uncertainty relation presents the constraints on the spread of measurement outcomes caused by the non-commutability of a pair of *** this article,we study the uncertainty relation of triple observables to explore the relationship between the standard deviations and the commutators of the *** derive and tighten the multiplicative form and weighted summation form uncertainty relations,which are found to be dependent not only on the commutation relations of each pair of the observables but also on a newly defined commutator in terms of all the three *** experimentally test the uncertainty relations in a linear optical *** experimental and numerical results agree well and show that the uncer-tainty relations derived by us successfully present tight lower bounds in the cases of high-dimensional observables and the cases of mixed *** method of deriving the uncertainty relation can be extended to more than three observables.

关键词： Heisenberg-Robertson uncertainty relation three observables commutation relation linear optical setup

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Numerical analysis for the effcacy of nasal surgery in obstructive sleep apnea hypopnea syndrome

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Acta Mechanica Sinica 2014年第2期30卷 250-258页

作者： Shen Yu Ying-Xi Liu Xiu-zhen sun Ying-Feng su Ying Wang Yin-zhe Gai State Key Laboratory of Structural Analysis for Industrial Equipment Dalian University of Technology Department of Otorhinalaryngology The Second Affiliated Hospital of Dalian Medical University

In the present study, we reconstructed upper airway and soft palate models of 3 obstructive sleep apnea-hypopnea syndrome（OSAHS） patients with nasal obstruction. The airflow distribution and movement of the soft palate before and after surgery were described by a numerical simulation method. The curative effect of nasal surgery was evaluated for the three patients with OSAHS. The degree of nasal obstruction in the 3 patients was improved after surgery. For 2 patients with mild OSAHS, the upper airway resistance and soft palate displacement were reduced after surgery. These changes contributed to the mitigation of respiratory airflow limitation. For the patient with severe OSAHS, the upper airway resistance and soft palate displacement increased after surgery, which aggravated the airway obstruction. The effcacy of nasal surgery for patients with OSAHS is determined by the degree of improvement in nasal obstruction and whether the effects on the pharynx are beneficial. Numerical simulation results are consistent with the polysomnogram（PSG） test results, chief complaints, and clinical findings, and can indirectly reflect the degree of nasal patency and improvement of snoring symptoms, and further,provide a theoretical basis to solve relevant clinical problems.

关键词： Nasal surgery Obstructive sleep apnea hypop-nea syndrome Fluid-solid interaction Numerical analysis

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