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An SDN/NFV Based Framework for Management and Deployment of Service Based 5G Core Network

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China Communications 2018年第10期15卷 86-98页

作者： lu Ma Xiangming Wen luhan Wang zhaoming lu Raymond Knopp Beijing Key Laboratory of Network System Architecture and Convergence Beijing University of Posts and Telecommunications Beijing 100876 China Beijing Advanced Innovation Center for Future Internet Technology Beijing 100124 China Communication System Department EURECOM Biot 06410 France

The traffic explosion and the rising of diverse requirements lead to many challenges for traditional mobile network architecture on flexibility, scalability, and deployability. To meet new requirements in the 5 G era, service based architecture is introduced into mobile networks. The monolithic network elements(e.g., MME, PGW, etc.) are split into smaller network functions to provide customized services. However, the management and deployment of network functions in service based 5 G core network are still big challenges. In this paper, we propose a novel management architecture for 5 G service based core network based on NFV and SDN. Combined with SDN, NFV and edge computing, the proposed framework can provide distributed and on-demand deployment of network functions, service guaranteed network slicing, flexible orchestration of network functions and optimal workload allocation. Simulations are conducted to show that the proposed framework and algorithm are effective in terms of reducing network operating cost.

关键词：管理体系结构核心网络服务框架网络函数活动网络可伸缩性网络元素

Mobile-Edge Computing Framework with Data Compression for Wireless Network in Energy Internet

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Tsinghua Science and Technology 2019年第3期24卷 271-280页

作者： luning Liu Xin Chen zhaoming lu luhan Wang Xiangming Wen the School of Information and Communication Engineering Beijing University of Posts and Telecommunications

Under the situations of energy dilemma, energy Internet has become one of the most important technologies in international academic and industrial areas. However, massive small data from users, which are too scattered and unsuitable for compression, can easily exhaust computational resources and lower random access possibility, thereby reducing system performance. Moreover, electric substations are sensitive to transmission latency of user data, such as controlling information. However, the traditional energy Internet usually could not meet requirements. Integrating mobile-edge computing makes energy Internet convenient for data acquisition,processing, management, and accessing. In this paper, we propose a novel framework for energy Internet to improve random access possibility and reduce transmission latency. This framework utilizes the local area network to collect data from users and makes conducting data compression for energy Internet possible. Simulation results show that this architecture can enhance random access possibility by a large margin and reduce transmission latency without extra energy consumption overhead.

关键词： energy Internet mobile-edge computing random access possibility data compression

CHRT:Clustering-Based Hybrid Re-Routing System for Traffic Congestion Avoidance

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China Communications 2021年第7期18卷 86-102页

作者： Jie Huo Xiangming Wen luning Liu luhan Wang Meiling Li zhaoming lu Beijing Laboratory of Advanced Information Networks and Beijing Key Laboratory of Network System Architecture and ConvergenceSchool of Information and Communication EngineeringBeijing University of Posts and TelecommunicationsBeijing 100876China Witcomm Open Source Communication Research Institute Beijing 100088China Taiyuan University of Science and Technology Taiyuan 030024China

Re-routing system has become an important technology to improve traffic efficiency.The traditional re-routing schemes do not consider the dynamic characteristics of urban traffic,making the planned routes unable to cope with the changing traf-fic conditions.Based on real-time traffic information,it is challenging to dynamically re-route connected vehicles to alleviate traffic congestion.Moreover,how to obtain global traffic information while reducing communication costs and improving travel efficiency poses a challenge to the re-routing system.To deal with these challenges,this paper proposes CHRT,a clustering-based hybrid re-routing system for traffic congestion avoidance.CHRT develops a multi-layer hybrid architecture.The central server accesses the global view of traffic,and the distributed part is composed of vehicles divided into clusters to reduce latency and communication overhead.Then,a clustering-based priority mechanism is proposed,which sets priorities for clusters based on realtime traffic information to avoid secondary congestion.Furthermore,to plan the optimal routes for vehicles while alleviating global traffic congestion,this paper presents a multi-metric re-routing algorithm.Through extensive simulations based on the SUMO traffic simulator,CHRT reduces vehicle traveling time,fuel consumption,and CO2 emissions compared to other systems.In addition,CHRT globally alleviates traffic congestion and improves traffic efficiency.

关键词： traffic congestion dynamic re-routing intelligent transportation system(ITS) real-time traffic information VANET

Experimental Study of Hygrothermal and Ultraviolet Aging on the Flexural Performance of Epoxy Polymer Mortar

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Acta Mechanica Solida Sinica 2021年第4期34卷 539-549页

作者： Xinhua Li Dongpeng Ma zhaoming lu Yiping Liu Zhenyu Jiang Liqun Tang Zejia Liu Licheng Zhou School of Civil Engineering and Transportation State Key Laboratory of Subtropical Building ScienceSouth China University of TechnologyGuangzhou510640China

This paper studies the effects of hygrothermal environment at different temperatures and ultraviolet(UV)radiation on the bending properties of epoxy polymer mortar(EPM).The microstructure changes of EPM during aging were studied by scanning electron microscopy,and the bending properties of EPM were predicted by the Arrhenius law.The results showed that the bending properties of EPM were greatly affected by the temperature in the hygrothermal aging,but not evidently affected by ultraviolet radiation in UV aging.The prediction of Arrhenius model shows that the EPM will steadily retain 92.8%,89.1%and 79.4%of the original flexural strength after long-term hygrothermal aging at 40∘C,60∘C and 80∘C,respectively.

关键词： Epoxy polymer mortar Ultraviolet radiation Hygrothermal environment Accelerated aging Flexural strength Arrhenius law

Inhibiting autophagy enhances sulforaphane-induced apoptosis via targeting NRF2 in esophageal squamous cell carcinoma

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Acta Pharmaceutica Sinica B 2021年第5期11卷 1246-1260页

作者： zhaoming lu Yandan Ren Li Yang Ang Jia Yi Hu Yu Zhao Wuduo Zhao Bin Yu Wen Zhao Jianying Zhang Guiqin Hou State Key Laboratory of Esophageal Cancer Prevention&Treatment School of Pharmaceutical SciencesZhengzhou UniversityZhengzhou 450001China Collaborative Innovation Center of Cancer Chemoprevention Zhengzhou 450001China Center of Advanced Analysis&Gene Sequencing Zhengzhou UniversityZhengzhou 450001China Henan Academy of Medical and Pharmaceutical Sciences Zhengzhou UniversityZhengzhou 450052China Key Laboratory of Advanced Drug Preparation Technologies Ministry of EducationZhengzhou UniversityZhengzhou 450001China

Sulforaphane(SFN), a natural anti-tumor compound from cruciferous vegetables, has been reported to induce protective autophagy to cancer cells, which might impair the anti-tumor efficiency of SFN. However, the accurate function and mechanism of SFN inducing autophagy in cancers are still obscure, especially in esophageal squamous cell carcinoma(ESCC), one of malignancies with high incidence in North China. Here, we mainly explored the potential function of autophagy upon SFN treatment in ESCC and molecular mechanism. We demonstrated that SFN could inhibit cell proliferation and induce apoptosis by activating caspase pathway. Moreover, we found activation of NRF2 pathway by SFN was responsible for the induction of autophagy and also a disadvantage element to the anti-tumor effects of SFN on ESCC, indicating that SFN might induce protective autophagy in ESCC. We, therefore,investigated effects of autophagy inhibition on sensitivity of ESCC cells to SFN and found that chloroquine(CQ) could neutralize the activation of SFN on NRF2 and enhance the activation of SFN on caspase pathway, thus improved the anti-tumor efficiency of SFN on ESCC in vitro and in vivo. Our study provides a preclinical rationale for development of SFN and its analogs to the future treatment of ESCC.

关键词： Sulforaphane Autophagy Chloroquine NRF2 Esophageal squamous cell carcinoma

公路施工过程对饮用水源地污染防治与控制策略研究

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环境科学与管理 2024年第6期49卷 29-32页

作者：卢辉王赵明广州市高速公路有限公司广东广州510308 交通运输部公路科学研究院北京100088

研究对花莞高速公路沿线的饮用水水源地和河流进行采样,通过分析水体中的pH、TDS、EC、不同类型的阴阳离子的含量和分布,研究在不同季节和温度条件下,公路施工过程对河流和饮用水源地的污染和影响范围,通过Piper图分析不同季节的饮用水... 详细信息

研究对花莞高速公路沿线的饮用水水源地和河流进行采样,通过分析水体中的pH、TDS、EC、不同类型的阴阳离子的含量和分布,研究在不同季节和温度条件下,公路施工过程对河流和饮用水源地的污染和影响范围,通过Piper图分析不同季节的饮用水和地表径流的离子类别和含量所占比例。研究发现水体TDS值先增后稳再降,整体满足淡水标准(<1000 mg/L)。公路施工对饮用水源地的污染控制手段有公路路线的合理规划,避开水源地,并优化停车区和服务区等位置。同时推广绿色和先进工艺,减少污染物排放,为公路施工中的水体保护提供科学依据和实用建议。

关键词：公路施工水源地污染防治控制策略

RICTOR/mTORC2 affects tumorigenesis and therapeutic efficacy of mTOR inhibitors in esophageal squamous cell carcinoma

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Acta Pharmaceutica Sinica B 2020年第6期10卷 1004-1019页

作者： zhaoming lu Xiaojing Shi Fanghua Gong Shenglei Li Yang Wang Yandan Ren Mengyin Zhang Bin Yu Yan Li Wen Zhao Jianying Zhang Guiqin Hou School of Pharmaceutical Sciences Zhengzhou UniversityZhengzhou 450001China Collaborative Innovation Center of Cancer Chemoprevention Zhengzhou 450001China School of Pharmacy Wenzhou Medical UniversityWenzhou 325035China The First Affiliated Hospital Zhengzhou UniversityZhengzhou 450052China Center of Advanced Analysis&Gene Sequencing Zhengzhou UniversityZhengzhou 450001China Henan Academy of Medical and Pharmaceutical Sciences Zhengzhou UniversityZhengzhou 450052China

Dysregulation of mTORCl/mTORC2 pathway is observed in many cancers and mTORC1 inhibitors have been used clinically in many tumor types;however,the mechanism of mTORC2 in tumorigenesis is still obscure.Here,we mainly explored the potential role of mTORC2 in esophageal squamous cell carcinoma(ESCC)and its effects on the sensitivity of cells to mTOR inhibitors.We demonstrated that RICTOR,the key factor of mTORC2,and p-AKT(Ser473)were excessively activated in ESCC and their overexpression is related to lymph node metastasis and the tumor-node-metastasis(TNM)phase of ESCC patients.Furthermore,we found that mTORCl/mTORC2 inhibitor PP242 exhibited more efficacious anti-proliferative effect on ESCC cells than mTORC1 inhibitor RAD001 due to RAD001-triggered feedback activation of AKT signal.Another,we demonstrated that down-regulating expression of RICTOR in ECa109 and EC9706 cells inhibited proliferation and migration as well as induced cell cycle arrest and apoptosis.Noteworthy,knocking-down stably RICTOR significantly suppresses RAD001-induced feedback activation of AKT/PRAS40 signaling,and enhances inhibition efficacy of PP242 on the phosphorylation of AKT and PRAS40,thus potentiates the antitumor effect of RAD001 and PP242 both in vitro and in vivo.Our findings highlight that selective targeting mTORC2 could be a promising therapeutic strategy for future treatment of ESCC.

关键词： RICTOR AKT RAD001 pp242 Esophageal squamous cell carcinoma

不同品种甜瓜的关键香气成分鉴定及感官特性形成分析

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现代食品科技 2024年第3期40卷 289-300页

作者：谢永恒卢绍浩刘崇盛许利平许高燕吴兆明张丽娜赵振杰高阳浙江中烟工业有限责任公司浙江杭州310000

该研究首先利用气相色谱-质谱-嗅闻技术(Gas Chromatography-Mass Spectrometry-Olfactometry,GC-MS-O)结合香气活力值(Odor Activity Value,OAV)从伽师瓜、黄河蜜瓜、西州密25号和西州密17号中分别鉴定出9、16、12和10种关键香气物质,其中的乙酸乙酯、乙酸丁酯和乙酸苄酯等7种香气物质是我国厚皮甜瓜主要的特征香气成分;采用定量描述分析确定了甜瓜的果香、瓜香、甜香、青香、花香和麝香-烘烤香6个感官特性并给出了相应的感官得分;利用聚类热图法分析了4种甜瓜中关键香气物质种类和含量的差异性;偏最小二乘回归法(Partial Least Squares Regression,PLSR)分析了甜瓜香气感官特性形成的原因。结果表明乙酸乙酯与甜瓜麝香-烘烤香感官属性形成相关;2-甲基丁基乙酸酯和乙酸丁酯与甜瓜果香感官属性形成相关;乙酸苄酯、异戊醛、(E,Z)-3,6-壬二烯-1-醇、硫代乙酸甲酯、(Z)-6-壬烯-1-醇和3-甲基丁酸乙酯与甜瓜的花香和瓜香感官属性形成呈显著相关性。该研究为我国厚皮甜瓜风味香气的改良以及其感官质量评价体系的构建提供了依据。

关键词：甜瓜气相色谱-质谱-嗅闻定量描述分析聚类热图分析偏最小二乘法回归分析

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9种杀菌剂对甜瓜细菌性果斑病的田间防效

寒旱农业科学 2024年第3期3卷 272-275页

作者：李丽吕兆明沈渭明张广荣白银市农业技术服务中心甘肃白银730900

为筛选高效低毒且对甜瓜细菌性果斑病防效较佳的农药试剂,以砂地甜瓜为研究对象,对9种高效低毒杀菌剂进行了田间筛选试验。结果表明,供试的9种药剂对甜瓜细菌性果斑病均具有一定的防治作用。77%硫酸铜钙可湿性粉剂500倍液第1次和第2次喷... 详细信息

为筛选高效低毒且对甜瓜细菌性果斑病防效较佳的农药试剂,以砂地甜瓜为研究对象,对9种高效低毒杀菌剂进行了田间筛选试验。结果表明,供试的9种药剂对甜瓜细菌性果斑病均具有一定的防治作用。77%硫酸铜钙可湿性粉剂500倍液第1次和第2次喷药7 d后防效均在70%以上,且第2次防效比第1次上升1.55个百分点,防治效果最佳。建议在白银市甜瓜果斑病防治中优先选用77%硫酸铜钙可湿性粉剂500倍液喷雾防治。

关键词：甜瓜果斑病防效