检索结果-南通市图书馆

Novel empirical model for predicting residual flexural capacity of corroded steel reinforced concrete beam

在线全文

学校读者我要写书评

暂无评论

Frontiers of Structural and Civil Engineering 2020年第4期14卷 888-906页

作者： zhao-hui lu Hong-Jun WANG Fulin QU Yan-Gang zhao Peiran LI Wengui LI Key Laboratory of Urban Security and Disaster Engineering of Ministry of Education Bejing University of TechnologyBeijing 100124China School of Civil Engineering Central South UniversityChangsha 410075China School of Civil and Environmental Engineering University of Technology SydneyNSW 2007Australia

In this study,a total of 177 flexural experimental tests of corroded reinforced concrete(CRC)beams were collected from the published *** database of flexural capacity of CRC beam was established by using unified and standardized experimental *** this database,the effects of various parameters on the flexural capacity of CRC beams were discussed,including beam width,the effective height of beam section,ratio of strength between longitudinal reinforcement and concrete,concrete compressive strength,and longitudinal reinforcement corrosion *** results indicate that the corrosion of longitudinal reinforcement has the greatest effect on the residual flexural capacity of CRC beams,while other parameters have much less *** addition,six available empirical models for calculating the residual flexural strength of CRC beams were also collected and compared with each other based on the established *** indicates that though five of six existing empirical models underestimate the flexural capacity of CRC beams,there is one model overestimating the flexural ***,a newly developed empirical model is proposed to provide accurate and effective predictions in a large range of corrosion ratio for safety assessment of flexural failure of CRC beams confirmed by the comparisons.

关键词： CRC beams flexural capacity steel corrosion database empirical models

Estimation of load and resistance factors using the thirdmoment method based on the 3P-Iognormal distribution

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Structural and Civil Engineering 2011年第3期5卷 315-322页

作者： Yan-Gang zhao zhao-hui lu Department of Architecture Kanagawa UniversityYokohama 221-8686Japan School of Civil Engineering Central South UniversityChangsha 410075China

Load and resistance factors are generally obtained using the first order reliability method(FORM)in which the design point should be determined and derivative-based iterations *** this article,the thirdmoment reliability index,based on the three-parameter lognormal(3P-lognormal)distribution,is investigated.A simple method based on the third-moment method for estimating load and resistance factors is then proposed,and a simple formula for the target mean resistance is also presented to avoid iterative *** the currently used method,the proposed method can be used to determine load and resistance factors,even when the probability density functions(PDFs)of the basic random variables are not ***,the proposed method does not require the iterative computation of derivatives or any design ***,the method provides a more convenient and effective way to estimate load and resistance factors in practical engineering *** examples are presented to demonstrate the advantages of the proposed third moment method for determining load and resistance factors.

关键词： load and resistance factors third-moment method three-parameter lognormal(3P-lognormal)distribution target mean resistance simple formula

Influence of formation in-situ stress on mechanical heterogeneity of shale through grid nanoindentation

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Petroleum Science 2022年第1期19卷 211-219页

作者： Mao Sheng Shi-Zhong Cheng zhao-hui lu Ye Zhang Shou-Ceng Tian Gen-Sheng Li College of Petroleum Engineering China University of Petroleum-Beijing102249PR China National and Local Joint Engineering Research Center of Shale Gas Exploration and Development Chongqing401120PR China

Mechanical heterogeneity is a major characteristic of the organic-rich *** relation between mechanical heterogeneity and formation in-situ stress has been seldomly addressed but important to understand hydraulic fracture propagation,wellbore stability,and hydrocarbon *** this paper,the grid nanoindentation technique was used to characterize the heterogeneity of the mechanical properties of Longmaxi organic-rich shales from various burial depths and in-situ *** measured elastic modulus and hardness of each sample are deconvolved into three phases including soft phase,medium stiff phase and stiff phase according to mineral *** the burial depth and corresponding in-situ stress increase,the overall elastic modulus and hardness of the sample ***,the percentage of soft minerals decreases,and the probability distribution tends to concentrate through 95%confidence interval evaluation which demonstrates weakened ***,SEM images provide evidence that extended cracking,initiated cracking,crushing and ductile deforming always occur around indentation *** confirms that even under deep buried depth and high in-situ stress,brittle fracture and ductile deformation can exist *** paper demonstrates the influence of in-situ stress on the heterogeneity of shale micromechanics.

关键词： Shale Heterogeneity Elastoplasticity Nanoindentation

Fascin promotes the motility and invasiveness of pancreatic cancer cells

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2011年第40期17卷 4470-4478页

作者： Yan-Feng Xu Shuang-Ni Yu zhao-hui lu Jian-Ping Liu Jie Chen Department of Pathology Peking Union Medical College Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Tsinghua University Beijing 100730 China

AIM:To explore the role of actin-bundling protein, fascin during the progression of pancreatic cancer. METHODS:The plasmid expressing human fascin-1 was stably transfected into the pancreatic cancer cell line MIA PaCa-2. The proliferation, cell cycle, motility, scattering, invasiveness and organization of the actin filament system in fascin-transfected MIA PaCa-2 cells and control non-transfected cells were determined. RESULTS:Heterogeneous overexpression of fascin markedly enhanced the motility, scattering, and inva-siveness of MIA PaCa-2 cells. However, overexpression of fascin had minimal effect on MIA PaCa-2 cell pro-liferation and cell cycle. In addition, cell morphology and organization of the actin filament system were distinctly altered in fascin overexpressed cells. When transplanted into BALB/c-nu mice, fascin-transfected pancreatic cancer cells developed solid tumors at a slightly slower rate, but these tumors displayed more aggressive behavior in comparison with control tumors. CONCluSION: Fascin promotes pancreatic cancer cell migration, invasion and scattering, thus contributes to the aggressive behavior of pancreatic cancer cells.

关键词： Fascin Invasiveness Motility Pancreaticcancer

Shaly detritus embedded epoxy-resin coated proppants

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Petroleum Science 2022年第4期19卷 1735-1744页

作者： zhao-hui lu Xiu-Ping Lan Yong Yuan Jian-Kun Zhou Si-Yuan Chen Fan Fan Ying-Chun Niu Shou-Zhen Li Kai-Yi Hu Yang Zhou Quan Xu Key Laboratory of Shale Gas Exploration Ministry of Natural ResourcesChongqing Institute of Geology and Mineral ResourcesChongqing401120China State Key Laboratory of Petroleum Resources and Prospecting Bejing Key Laboratory of Biogas Upgrading UtlizationHarvard SEAS-CUPB Joint Laboratory on Petroleum ScienceChina University of Petroleum(Beijing)Beijing102249China

Proppant plays a significant role in the hydraulic fracturing process, which can affect the production of oil and gas wells. Due to the high density and low adhesion force, the settling speed of traditional proppants is fast, which will lead to the blockage of a crack channel. In this study, a proppant with double layer structure is fabricated by coating epoxy-resin and shaly detritus on ceramic proppants for the first time,respectively. The epoxy-resin enables the shaly detritus to be coated on the proppant successfully, which can provide a new method for shaly detritus treatment. The adhesive ability of shaly detritus and epoxyresin coated proppants(SEPs) is improved by 10.4% under the load force of 500 n N, which prolongs the time for the fracture to close. At the same time, the suspending ability of SEPs is two times higher than the uncoated proppants. Once the guar gum solution concentration is 0.3 wt%, the settling time of SEPs is36.7% longer than that of the uncoated proppants, which can effectively reduce the settlement of proppants in the crack. In addition, the hydrophobicity of the SEPs is enhanced, which reduces the wateroil ratio of crude oil and increases the liquid conductivity tested by deionized water. In summary, this new proppant is expected to promote the development of unconventional oil and gas resources.

关键词： Coated proppant Shaly detritus Hydrophobicity Conductivity

Effect of Soil Drought Stress on Leaf Water Status, Membrane Permeability and Enzymatic Antioxidant System of Maize

在线全文

学校读者我要写书评

暂无评论

Pedosphere 2006年第3期16卷 326-332页

作者： BAI Li-Ping SUI Fang-Gong GE Ti-Da SUN zhao-hui lu Yin-Yan ZHOU Guang-Sheng Laboratory of Quantitative Vegetation Ecology Institute of Botany Chinese Academy of Sciences Beijing 100093 （China） Laiyang Agricultural College Laiyang Shandong 265200 （China）

A simulation experiment on the responses of maize (Zea mays L.) from the third leaf stage to maturity for different soil water levels (well-watered, moderately stressed, and severely stressed) was conducted by controlling irrigation and using a mobile rain shelter in a neutral loam, meadow soil to determine the effects on leaf water status, membrane permeability and enzymatic antioxidant system for different growth stages. The results indicated that drought stress relied on drought intensity and duration, with more severe drought stress creating more serious effects on maize. Compared with well-watered conditions, during the silking and blister stages moderate stress did not significantly change the relative water content (RWC) and did change significantly the relative conductivity (RC) (P < 0.05) of the leaves; however, severe stress did significantly decrease (P < 0.01) the leaf RWC and increase (P < 0.01) membrane permeability (leaf relative conductivity). Furthermore, under severe drought stress antioxidant enzyme activities declined significantly (P < 0.01) in later stages, namely for superoxide dismutase (SOD) the tasseling and blister stages, for peroxidase (POD) the milk stage, and for catalase (CAT) during the tasseling, blister, and milk stages. Meanwhile, membrane lipid peroxidation (measured as malondialdehyde content) significantly increased (P < 0.01) in all stages.

关键词： drought stress enzymatic antioxidant system leaf water status maize membrane permeability

Understanding the local structure and thermophysical behavior of Mg-La liquid alloys via machine learning potential

在线全文

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 439-449页

作者： Jia zhao Taixi Feng Guimin lu National Engineering Research Center for Integrated Utilization of Salt Lake Resource East China University of Science and TechnologyShanghai 200237China Joint International Laboratory for Potassium and Lithium Strategic Resources East China University of Science and TechnologyShanghai 200237China

The local structure and thermophysical behavior of Mg-La liquid alloys were in-depth understood using deep potential molecular dynamic(DPMD) simulation driven via machine learning to promote the development of Mg-La alloys. The robustness of the trained deep potential(DP) model was thoroughly evaluated through several aspects, including root-mean-square errors(RMSEs), energy and force data, and structural information comparison results;the results indicate the carefully trained DP model is reliable. The component and temperature dependence of the local structure in the Mg-La liquid alloy was analyzed. The effect of Mg content in the system on the first coordination shell of the atomic pairs is the same as that of temperature. The pre-peak demonstrated in the structure factor indicates the presence of a medium-range ordered structure in the Mg-La liquid alloy, which is particularly pronounced in the 80at% Mg system and disappears at elevated temperatures. The density, self-diffusion coefficient, and shear viscosity for the Mg-La liquid alloy were predicted via DPMD simulation, the evolution patterns with Mg content and temperature were subsequently discussed, and a database was established accordingly. Finally, the mixing enthalpy and elemental activity of the Mg-La liquid alloy at 1200 K were reliably evaluated,which provides new guidance for related studies.

关键词： magnesium-lanthanum liquid alloys local structure macroscopic properties thermodynamic behavior deep potential mo-lecular dynamic simulation

Association between Self-reported Snoring and Prediabetes among Adults Aged 40 Years and Older without Diabetes

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2017年第7期130卷 791-797页

作者： Hai-Bin Wang Wen-Hua Yan Jing-Tao Dou zhao-hui lu Bao-An Wang Yi-Ming Mu Department of Endocrinology Chinese People's Liberation Army General Hospital Beijing 100853 China

Background：Several previous studies have shown that snoring is associated with glucose metabolism and the development of diabetes,but rare study has shown the association between snoring frequency and prediabetes,particularly in *** hypothesized that individuals who snore might have a higher risk of *** study aimed to investigate the association between self-reported snoring and prediabetes in a Chinese ***：A cross-sectional study was performed in three large communities of Beijing from December 2011 to August 2012 by recruiting individuals aged ≥40 years *** participants were requested to complete a detailed questionnaire and undergo anthropometric measurements.A 75 g oral glucose tolerance test was performed in individuals without *** samples of all participants were collected;blood glucose and blood fat levels were *** logistic regression models were built to assess the association between snoring frequency and ***：A total of 13,592 participants （female：66.56%;mean age：56.8 ＆#177; 7.9 years;mean body mass index：25.5 ± 3.4 kg/m2） were included in the final *** these,30.9% were diagnosed with prediabetes,while 41.3% and 25.4% had occasional and habitual snoring,*** snoring was associated with an increased risk of prediabetes （odds ratio [OR]：1.3,95% confidence interval [CI]：1.1-1.4,P 〈 0.001）,after adjusting for diabetes and sleep-related confounders in the multivariable *** snoring was also associated with isolated impaired fasting glucose （IFG;OR：1.3,95% CI：1.0-1.6;P 〈 0.001） and isolated impaired glucose tolerance （IGT;OR：1.3,95% CI：1.2-1.5;P 〈 0.001）,but not IFG ＋ IGT （OR：1.1,95% CI：0.9-1.4;P =0.281）.When stratified by total cholesterol （TC） levels,this association between habitual snoring and prediabetes was observed only in individuals with TC 〈5.6 mmol/L （OR：1.4,95% CI：1.2-1.6;P〈 0.001）.Conclusions：Habitual snoring is associated with predia

关键词： Cholesterol Community Cross-sectional Studies Prediabetic State Snoring

Inhibitory effect of Ca2+ on in vivo gene transfer by electroporation

在线全文

学校读者我要写书评

暂无评论

Acta Pharmacologica Sinica 2006年第3期27卷 307-310页

作者： Yong-gang zhao~2 hui-li lu~2 Jin-liang PENG~2 Yu-hong XU~(2,3,4) ~2School of Life Science and Biotechnology and ~3School of Pharmacy,Shanghai Jiaotong University,Shanghai 200240,China School of Life Science and Biotechnology Shanghai Jiaotong University Shanghai China School of Pharmacy Shanghai Jiaotong University Shanghai China

Aim:To investigate the specific effects of Ca2+on transgene expression duringelectroporation-mediated gene transfer in ***:Skeletal muscle andskin were subjected to in vivo electroporation with a luciferase reporter plasmid,with or without Ca2+and various other ***:For in vivo electroporation,the presence of just 10 mmol/L Ca2+in the DNA solution drastically reduced theresulting transgene expression,to less than 5% of control *** Ca2+,notother ions,caused inhibition,and the effect was not tissue ***,even when Ca2+ions were delivered by electroporation before orafter DNA administration,similar effects were still ***:Theinhibitory effect of Ca2+on in vivo gene transfer by electroporation is specific,ie,the inhibitory effect may be related to the cell membrane properties afterelectroporation and the subsequent resealing event.

关键词： gene therapy electroporation gene transfer calcium ion