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Return to work in young and middle-aged colorectal cancer survivors:Factors influencing self-efficacy,fear,resilience,and financial toxicity

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World Journal of Gastroenterology 2025年第1期31卷 79-92页

作者： Dan Hu Yue Li Hua Zhang Lian-Lian Wang Wen-Wen Liu Xin Yang ming-zhao Xiao Hao-Ling Zhang Juan Li Department of Nursing The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Nursing National Clinical Research Center for Child Health and DisordersMinistry of Education Key Laboratory of Child Development and DisordersChildren’s Hospital of Chongqing Medical UniversityChongqing 400014China Department of Gastrointestinal Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Biomedical Science Advanced Medical and Dental InstituteUniversity Sains MalaysiaPenang 13200Malaysia Academic Affairs Office The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China

BACKGROUND Return to work(RTW)serves as an indication for young and middle-aged colorectal cancer(CRC)survivors to resume their normal social ***,these survivors encounter significant challenges during their RTW ***,scientific research is necessary to explore the barriers and facilitating factors of returning to work for young and middle-aged CRC *** To examine the current RTW status among young and middle-aged CRC survivors and to analyze the impact of RTW self-efficacy(RTW-SE),fear of progression(FoP),eHealth literacy(eHL),family resilience(FR),and financial toxicity(FT)on their RTW *** A cross-sectional investigation was adopted in this *** September 2022 to February 2023,a total of 209 participants were recruited through a convenience sampling method from the gastrointestinal surgery department of a class A tertiary hospital in *** investigation utilized a general information questionnaire alongside scales assessing RTW-SE,FoP,eHL,FR,and *** analyze the factors that influence RTW outcomes among young and middle-aged CRC survivors,Cox regression modeling and Kaplan-Meier survival analysis were *** A total of 43.54%of the participants successfully returned to work,with an average RTW time of 100 *** regression univariate analysis revealed that RTW-SE,FoP,eHL,FR,and FT were significantly different between the non-RTW and RTW groups(P<0.05).Furthermore,Cox regression multivariate analysis identified per capita family monthly income,job type,RTW-SE,and FR as independent influencing factors for RTW(P<0.05).CONCLUSION The RTW rate requires further *** levels of RTW-SE and FR were found to significantly increase RTW among young and middle-aged CRC *** professionals should focus on modifiable factors,such as RTW-SE and FR,to design targeted RTW support programs,thereby facilitating their timely reintegration into mainstream society.

关键词： Return to work Colorectal neoplasms Return-to-work self-efficacy Fear of progression Family resilience Financial toxicity

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Numerical Simulation of Rotor Flow Field Based on Overset Grids and Several Spatial and Temporal Discretization Schemes

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Chinese Journal of Aeronautics 2012年第2期25卷 155-163页

作者： zhao ming CAO Yihua School of Aeronautic Science and Engineering Beihang UniversityBeijing 100191China

A numerical method based on solutions of Euler/Navier-Stokes （N-S） equations is developed for calculating the flow field over a rotor in hover. Jameson central scheme, van Leer flux-vector splitting scheme, advection upwind splitting method （AUSM） scheme, upwind AUSM/van Leer scheme, AUSM＋ scheme and AUSMDV scheme are implemented for spatial discretization, and van Albada limiter is also applied. For temporal discretization, both explicit Runge-Kutta method and implicit lower-upper symmetric Gauss-Seidel （LU-SGS） method are attempted. Simultaneously, overset grid technique is adopted. In detail, hole-map method is utilized to identify intergrid boundary points （IGBPs）. Furthermore, aimed at identification issue of donor elements, inverse-map method is implemented. Eventually, blade surface pressure distributions derived from numerical simulation are validated compared with experimental data, showing that all the schemes mentioned above have the capability to predict the rotor flow field accurately. At the same time, vorticity contours are illustrated for analysis, and other characteristics are also analyzed.

关键词： rotors computational fluid dynamics overset grids finite volume method helicopters

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Stochastic optimal control of cable vibration in plane by using axial support motion

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Acta Mechanica Sinica 2011年第4期27卷 578-586页

作者： ming zhao Wei-Qiu Zhu Department of Mechanics State Key Laboratory of Fluid Power Transmission and Control Zhejiang University 310027 Hangzhou China

A stochastic optimal control strategy for a slightly sagged cable using support motion in the cable axial direction is proposed. The nonlinear equation of cable motion in plane is derived and reduced to the equations for the first two modes of cable vibration by using the Galerkin method. The partially averaged Ito equation for controlled system energy is further derived by applying the stochastic averaging method for quasi-non-integrable Hamiltonian systems. The dynamical programming equation for the controlled system energy with a performance index is established by applying the stochastic dynamical programming principle and a stochastic optimal control law is obtained through solving the dynamical programming equation. A bilinear controller by using the direct method of Lyapunov is introduced. The comparison between the two controllers shows that the proposed stochastic optimal control strategy is superior to the bilinear control strategy in terms of higher control effectiveness and efficiency.

关键词： Stay cable Active control - Stochastic optimalcontrol Dynamical programming principle

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Influences of Leading-Edge Tubercle Amplitude on Airfoil Flow Field

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Journal of Thermal Science 2023年第4期32卷 1335-1344页

作者： zhao ming WEI Tong zhao Yijia LIU Zhengxian Department of Mechanics School of Mechanical EngineeringTianjin UniversityTianjin300350China Tianjin Key Laboratory of Modern Engineering Mechanics Tianjin UniversityTianjin300350China

The influences of leading-edge tubercle amplitude on airfoil flow field have been analyzed at high angle of *** accuracy of a large eddy simulation(LES)research is validated through quantitative comparisons with corresponding experimental ***,a proper orthogonal decomposition(POD)analysis has been carried out based on the unsteady flow field and the fluid mechanisms of corresponding POD modes have been ***,the influences of leading-edge tubercle amplitude have been *** the streamwise vorticity is larger than that of small amplitude cases,the momentum transfer process at peaks is more obvious for large amplitude,leading to delayed flow *** amplitude and wavelength play important roles in the generation of laminar separation bubble(LSB)at ***,the Karman vortex shedding process takes place at specific trough sections as pairs of periodic spatial structures exist in the dominant POD *** destruction of Karman vortex shedding process is strengthened along with the increase of amplitude.

关键词： leading-edge tubercle airfoil flow field proper orthogonal decomposition

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Upper mantle seismic anisotropy beneath a convergent boundary:SKS waveform modeling in central Tibet

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Science China Earth Sciences 2014年第4期57卷 759-776页

作者： zhao Liang zhao ming LU Gang State Key Laboratory of Lithospheric Evolution Institute of Geology and GeophysicsChinese Academy of Sciences

This study used SKS waveforms from the International Deep Profiling of Tibet and the Himalayas(INDEPTH) III dataset and a new 2D method for modeling seismic waves in anisotropic media to construct an image of anisotropic structures beneath central Tibet.A preferred model revealed three-segment anisotropic structures in the upper mantle beneath the study *** modeling demonstrated that the anisotropy was mainly generated by the lithosphere but not the asthenosphere,and that an anisotropic model with a flatter axis of symmetry provides a more consistent interpretation of the observations than models having steeply dipping symmetry axes.A relatively low velocity zone may underlie or intermingle with the anisotropic structures in the northern portion of the *** tests also indicate that variations in the elastic constants and depth extent of the anisotropy assumed by the calculations do not affect the general conclusions,although trade-offs exist among certain model *** modeling results suggest that the complex seismic structures in central Tibet were associated with underthrusting of the Indian lithosphere beneath the Asian lithosphere;the inferred flat symmetry axis of the anisotropy was likely generated during this collision *** this were not the case,the inherited anisotropy would exhibit a steeply dipping axis of symmetry,parallel to the direction of underthrusting.

关键词： waveform modeling spectral element method upper mantle anisotropy central Tibet

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Evaluation of earthquake signal characteristics for early warning

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Earthquake Engineering and Engineering Vibration 2012年第3期11卷 435-443页

作者： Kong Qingkai zhao ming Building Engineering Department Tongji UniversityShanghai 200092China

This paper evaluates different characteristics for earthquake early warning. The scaling relationships between magnitude, epicenter distance and calculated parameters are derived from earthquake event data fi＇om USGS. The standard STA/LTA method is modified by adding two new parameters to eliminate the effects of the spike-type noise and small pulsetype noise ahead of the onset of the P-wave. After the detection of the P-wave, the algorithm extracts 12 kinds of parameters from the first 3 seconds of the P-wave. Then stepwise regression analysis of these parameters is performed to estimate the epicentral distance and magnitude. Six different parameters are selected to estimate the epicentral distance, and the median error for all 419 estimates is 16.5 krn. Four parameters are optimally combined to estimate the magnitude, and the mean error for all events is 0.0 magnitude units, with a standard deviation of 0.5. Finally, based on the estimation results, additional work is proposed to improve the accuracy of the results.

关键词： earthquake early warning epicentral distance estimation magnitude estimation

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Scour Effect on Dynamic Characteristics and Responses of Offshore Wind Turbines

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Computer Modeling in Engineering & Sciences 2020年第8期124卷 433-457页

作者： Dongyue Tang ming zhao College of Civil Engineering Tongji UniversityShanghaiChina

The monopile foundation is the main form of offshore wind turbine foundation,and its surrounding scouring pit will reduce the constraints of the soil on the piles,which makes wind turbine foundation instability a key issue affecting the structural safety of offshore wind *** previous studies,the rotating rotor and control system are neglected when studying the influence of scour on the offshore wind turbine *** this paper,the numerical model of the blade-tower-monopile integrated offshore wind turbine is established,and the influence of scour on the dynamic characteristics of wind turbine is obtained considering parameters,such as blade azimuth,pitch angle,rotor speed,and soil *** calculating wind load by using the modified Blade Element Momentum theory,the impact of scour on the wind-induced response of a monopile wind turbine is achieved,considering control system and aeroelastic ***,a reference method is proposed for estimating scour depth according to the monopile foundation offshore wind turbine wind-induced response.

关键词： Scour effect offshore wind turbine dynamic characteristics dynamic response

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Web software reliability modeling with random impulsive shocks

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Journal of Systems Engineering and Electronics 2014年第2期25卷 349-356页

作者： Jianfeng Yang ming zhao Wensheng Hu College of Computer Science & Technology Guizhou University Reliability Engineering Center Guizhou University Faculty of Technology and Sustainable Development University of Gvle

As the web-server based business is rapidly developed and popularized, how to evaluate and improve the reliability of web-servers has been extremely important. Although a large num- ber of software reliability growth models （SRGMs）, including those combined with multiple change-points （CPs）, have been available, these conventional SRGMs cannot be directly applied to web soft- ware reliability analysis because of the complex web operational profile. To characterize the web operational profile precisely, it should be realized that the workload of a web server is normally non-homogeneous and often observed with the pattern of random impulsive shocks. A web software reliability model with random im- pulsive shocks and its statistical analysis method are developed. In the proposed model, the web server workload is characterized by a geometric Brownian motion process. Based on a real data set from IIS server logs of ICRMS website （***）, the proposed model is demonstrated to be powerful for estimating impulsive shocks and web software reliability.

关键词： web software software reliability growth model(SRGM) change-point (CP) impulsive shocks geometric Brown-ian motion.

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Mechanisms underlying syntactic and semantic processing of Chinese simple sentences Evidence from event-related brain potentials

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Neural Regeneration Research 2011年第25期6卷 1937-1941页

作者： Huanhai Fang ming zhao Overseas Education College Xiamen University Xiamen 361005 Fujian Province China Center of Cognitive Science Zhejiang University Hangzhou 324000 Zhejiang Province China

This study sought to test the processing of three types of sentences in Chinese, as correct sentences, semantic violation sentences, and sentences containing semantic and syntactic violations, based on the following sentence pattern：＂subject （noun）＋ yi/gang/zheng ＋ predicate （verb）＂. Event-related potentials on the scalp were recorded using 32-channel electroencephalography. Compared with correct sentences, target words elicited an early left anterior negativity （N400） and a later positivity （P600） over frontal, central and temporal sites in sentences involving semantic violations. In addition, when sentences contained both semantic and syntactic violations, the target words elicited a greater N400 and P600 distributed in posterior brain areas. These results indicate that Chinese sentence comprehension involves covert grammar processes.

关键词： Chinese syntactic semantic event-related brain potentials processing mechanism

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HISP： a hybrid intelligent approach for identifying Jirected signaling pathways

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Journal of Molecular Cell Biology 2017年第6期9卷 453-462页

作者： Xing-ming zhao Shan Li Institute of Science and Technology for Brain-Inspired Intelligence Fudan University Shanghai 200433 China Department of Mathematics Shanghai University Shanghai 200444 China

Signal transduction plays important roles in biological systems. Unfortunately, our knowledge about signaling pathways is far from complete. Specifically, the direction of signaling flows is less known even though the signaling molecules of some signaling pathways have been determined. In this paper, we propose a novel hybrid intelligent method, namely HISP （Hybrid Intelligent approach for identifying directed Signaling Pathways）, to determine both the topologies of signaling pathways and the direction of signaling flows within a pathway based on integer linear programming and genetic algorithm. By integrating the protein-protein interaction, gene expression, and gene knockout data, our HISP approach is able to determine the optimal topologies of signaling pathways in an accurate way. Benchmark results on yeast MAPK signaling pathways demonstrate the efficiency of our proposed approach. When applied to the EGFR/ErbB signaling pathway in human hepatocytes, HISP unveils a high-resolution signaling path- way, where many signaling interactions were missing by existing computational approaches.

关键词： EGFR/ErbB signaling pathway genetic algorithm hybrid intelligence integer linear programming MAPK signaling path-way signaling pathway

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