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恒河猴自发性脂肪瘤的病例分析

实验动物科学 2020年第4期37卷 59-63页

作者：杨凤梅李艳艳刘权陈丽雄王俊斌赵远马进徐鸿界禹文海和占龙中国医学科学院/北京协和医学院医学生物学研究所云南省重大传染病疫苗研发重点实验室昆明650118

在人工饲养猴场中发现一只雄性恒河猴腹部有一隆起肿块,采食、饮水、排便等皆正常。对其进行保定触诊,肿块皮肤完整,肿块组织边界清楚,质地硬,实质感较强,不规则形,直径约10 cm,触诊无明显痛感;用针管刺入肿块组织抽取无液体样内容物。... 详细信息

在人工饲养猴场中发现一只雄性恒河猴腹部有一隆起肿块,采食、饮水、排便等皆正常。对其进行保定触诊,肿块皮肤完整,肿块组织边界清楚,质地硬,实质感较强,不规则形,直径约10 cm,触诊无明显痛感;用针管刺入肿块组织抽取无液体样内容物。经B超检测该肿块内组织形状规则,边界清晰,包膜回声及少许血流信号,呈纤维素样变;检查体温正常;血液生理及生化指标检测,结果与正常猴比较:ALP升高,TP、ALB、TC、RBC、HCT降低;实施肿块切除手术,取肿块组织切片镜检,确诊为脂肪瘤。经手术后经过术后护理,该恒河猴预后良好。

关键词：恒河猴脂肪瘤检测

Current status of applying microwave-associated catalysis for the degradation of organics in aqueous phase – A review

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Journal of Environmental Sciences 2019年第7期31卷 119-135页

作者： Chao Xue Yanpeng Mao Wenlong Wang zhanlong Song Xiqiang Zhao Jing Sun Yanxiang Wang School of Energy and Power Engineering Shandong University School of Material Science & Engineering Shandong University

Interactions between microwaves and certain catalysts can lead to efficient, energy-directed convergence of a relatively dispersed microwave field onto the reactive sites of the catalyst,which produces thermal or discharge effects around the catalyst. These interactions form"high-energy sites"(heS) that promote energy efficient utilization and enhanced in situ degradation of organic pollutants. This article focuses on the processes occurring between microwaves and absorbing catalysts, and presents a critical review of microwave-absorbing mechanisms. This article also discusses aqueous phase applications of relevant catalysts(ironbased, carbon-based, soft magnetic, rare earth, and other types) and microwaves, special effects caused by the dimensions and structures of catalytic materials, and the optimization and design of relevant reactors for microwave-assisted catalysis of wastewater. The results of this study demonstrate that microwave-assisted catalysis can effectively enhance the degradation rate of organic compounds in an aqueous phase and has potential applications to a variety of engineering fields such as microwave-assisted pyrolysis, pollutant removal,material synthesis, and water treatment.

关键词： Microwaves Catalysts High energy sites Organics degradation Aqueous phase

Biomarkers for immune checkpoint inhibitors in colorectal cancer:recent advances and future perspectives

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Cancer Biology & Medicine 2023年第9期20卷 633-639页

作者： Changjiang Yang Long Zhao Yilin Lin Shan Wang Yingjiang Ye zhanlong Shen Department of Gastroenterological Surgery Laboratory of Surgical OncologyKey Laboratory of Colorectal Cancer Diagnosis and Treatment ResearchPeking University People’s HospitalBeijing 100044China

Colorectal cancer(CRC)has become a major threat to human *** years,improvements have been seen in the treatment of advanced CRC with immune checkpoint inhibitors(ICIs).Nonetheless,sensitivity to ICIs notably varies among patients,thus greatly limiting clinical applications of ICIs in ***,the identification of biomarkers that can accurately distinguish between ICI-sensitive and drug-resistant patients is of utmost *** biomarkers are essential for selecting appropriate treatment regimens and achieving precision therapy(Figure 1).The biomarkers discussed below provide insights into the advancements made in this field(Table 1).

关键词： cancer colorectal Figure

CD26/二肽基肽酶4与甲状腺乳头状癌的相关性研究进展

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当代医学 2024年第3期30卷 192-194页

作者：张作宇王占龙付福山蒙炯包头医学院研究生院内蒙古包头014000 包头医学院第一附属医院头颈、甲状腺外科内蒙古包头014000

随着近年来甲状腺乳头状癌(PTC)发病率的不断上升,寻找PTC诊断和预后的指标迫在眉睫。目前国内外多数CD26/二肽基肽酶4(DPP4)与PTC关系的研究均显示,CD26/DPP4在PTC组织中高表达,但是否与淋巴结转移、肿瘤直径、肿瘤分期等因素呈正相关... 详细信息

随着近年来甲状腺乳头状癌(PTC)发病率的不断上升,寻找PTC诊断和预后的指标迫在眉睫。目前国内外多数CD26/二肽基肽酶4(DPP4)与PTC关系的研究均显示,CD26/DPP4在PTC组织中高表达,但是否与淋巴结转移、肿瘤直径、肿瘤分期等因素呈正相关仍不明确。既往研究存在实验方法局限、地域局限、选定病例类型粗略等的问题。因此,基于目前CD26/DPP4与PTC关系的研究现状,本研究通过检索大量文献,对国内外部分学者的相关文献进行了梳理和总结,以明确对CD26/DPP4与PTC的关系,为寻找PTC诊断和预后指标提供借鉴。

关键词： CD26/二肽基肽酶4 甲状腺肿瘤甲状腺乳头状癌免疫组织化学法

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地震地貌切片解释技术及应用

石油地球物理勘探 2020年第3期55卷 669-677,473-474页

作者：杨占龙中国石油勘探开发研究院西北分院甘肃兰州730020 中国石油集团油藏描述重点实验室甘肃兰州730020

时间切片、沿层切片、地层切片、层拉平技术等是目前地震资料地质解释中分析构造、沉积与古地貌等的常用方法。针对沉积体系精细研究的特定需要,提出地震地貌切片的概念并归纳其制作方法。地震地貌切片是指沿地震数据体中反映一定时期... 详细信息

时间切片、沿层切片、地层切片、层拉平技术等是目前地震资料地质解释中分析构造、沉积与古地貌等的常用方法。针对沉积体系精细研究的特定需要,提出地震地貌切片的概念并归纳其制作方法。地震地貌切片是指沿地震数据体中反映一定时期古地貌特征的部位制作的一种地震切片类型。地质体空间追踪法和小时窗透视法是地震地貌切片制作的有效方法。地震地貌切片具有对约束层位等时性要求低而适应性广、从古地貌角度出发易于被地质人员理解而实用性强、采用将今论古对比分析方法而预测结果可靠的优势,是利用切片技术进行精细地震沉积分析的一种有效方法。通过实际应用,证实了地震地貌切片概念的科学性、切片制作方法的合理性及分析结果的有效性。

关键词：地震地貌切片沉积体系地质体追踪小时窗透视层拉平

VOC degradation by microwave-induced metal discharge and thermal destruction:a comparative study

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Waste Disposal and Sustainable Energy 2019年第4期1卷 261-270页

作者： Yuting Lv Yuli Zhou Wenlong Wang Jing Sun zhanlong Song Ke Wang National Engineering Laboratory for Coal-fired Pollutants Emission Reduction Shandong UniversityJinan 250100China Department of Engineering Physics Tsinghua UniversityBeijing 100084China

The effective treatment of volatile organic compounds(VOCs)is essential because of their direct effects on air pollution and human *** paper introduces microwave-induced metal discharge as a highly effective and byproduct value-added approach to degrade high-concentration toluene as a model *** effect of the factors that influence the discharge intensity,including the metal type(Fe,Cu,Ni,Zn)and amount,was *** efficiency of toluene can reach 79.76% under optimal discharge *** addition,the discharge method was compared with traditional thermal destruction at 700℃,900℃ and 1100℃.The gaseous and liquid cracking products of toluene produced by the microwave-induced metal discharge method were almost similar to those obtained under thermal destruction at 900℃;however,the solid-phase discharge products were nanoparticles that demonstrated good graphitization,while the thermal destruction products were amorphous *** work offers an effective and flexible way to degrade high-concentration VOCs and also provides an application reference for biomass tar cracking and removal of other organic pollutants.

关键词： Volatile organic compounds Toluene Three-phase products Degradation

基于相对熵-TOPSIS的机床可再制造性方案评价系统开发

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制造技术与机床 2024年第6期 147-152页

作者：郭秀珍龚青山刘敏江志刚曹占龙陈君文湖北汽车工业学院湖北十堰442002 武汉科技大学湖北武汉430081

可再制造性评价是机械装备再制造过程的重要环节,可再制造性评价方案直接影响再制造机床的质量及成本。针对机床可再制造性方案评价问题,提出了基于相对熵-TOPSIS的机床可再制造性方案的评价方法。首先,建立了基于机床易回收性、可拆解... 详细信息

可再制造性评价是机械装备再制造过程的重要环节,可再制造性评价方案直接影响再制造机床的质量及成本。针对机床可再制造性方案评价问题,提出了基于相对熵-TOPSIS的机床可再制造性方案的评价方法。首先,建立了基于机床易回收性、可拆解性、再制造技术性的可再制造性评价体系;然后,采用可拓层次分析法计算各指标权重,并应用相对熵-TOPSIS的评价方法进行最优方案筛选;最后,结合C#语言、SQL数据库等工具开发了机床的可再制造性方案评价系统,并将其应用于某机床制造厂滚齿机床再制造,对该方法可行性进行应用验证。

关键词：机床可再制造性相对熵-TOPSIS 评价系统

Microwave-induced high-energy sites and targeted energy transition promising for efficient energy deployment

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Frontiers in Energy 2022年第6期16卷 931-942页

作者： Jing SUN Guanqun YU Kui AN Wenlong WANG Biao WANG Zhenyu JIANG Chenggong SUN YanpengMAO Xiqiang ZHAO zhanlong SONG National Engineering Laboratory for Reducing Emissions from Coal Combustion Engineering Research Center of Environmental Thermal Technology(Ministry of Education)Shandong Key Laboratory of Energy Carbon Reduction and Resource UtilizationSchool of Energy and Power EngineeringShandong UniversityJinan 250061China Faculty of Engineering University of NottinghamNottingham NG72RDUK

Diverse interactions between microwaves and irradiated media provide a solid foundation for identifying novel organization pathways for energy *** this study,a high-energy-site phenomenon and targeted-energy transition mechanism were identified in a particular microwave heating(MH)*** discharges were observed when microwaves were imposed on irregularly sized SiC particles,producing tremendous heat that was 8-fold the amount generated in the discharge-free *** efficiency was thereby greatly improved in the electricity-microwaves-effective heat ***,the dispersed microwave field energy concentrated in small sites,where local temperatures could reach 2000℃–4000℃,with the energy density reaching up to 4.010^(5) W/*** can be called a high-energy site phenomenon which could induce further processes or reactions enhancement by coupling effects of heat,light,and *** whole process,including microwave energy concentration and intense site-energy release,shapes a targeted-energy transition mechanism that can be optimized in a controlled manner through morphology *** particular,the discharge intensity,frequency,and high-energy sites were strengthened through the fabrication of sharp nano/microstructures,conferring twice the energy efficiency of untreated metal *** microwave-induced high-energy sites and targeted energy transition provide an important pathway for high-efficiency energy deployment and may lead to promising applications.

关键词： microwave discharge high-energy sites targeted-energy transition morphology design energy efficiency

Systematic investigation of SO_(2) adsorption and desorption by porous powdered activated coke:Interaction between adsorption temperature and desorption energy consumption

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Chinese Journal of Chemical Engineering 2022年第8期35卷 140-148页

作者： Jun Li Liqiang Zhang Xiao Zhu Mengze Zhang Tai Feng Xiqiang Zhao Tao Wang zhanlong Song Chunyuan Ma National Engineering Laboratory for Reducing Emissions from Coal Combustion Engineering Research Center of Environmental Thermal Technology of Ministry of EducationShandong Key Laboratory of Energy Carbon Reduction and Resource UtilizationSchool of Energy and Power EngineeringShandong UniversityJinan 250061China College of Mechanical and Electronic Engineering Shandong University of Science and TechnologyQingdao 266590China

Porous carbon materials have been widely used for the removal of SO_(2) from flue *** main objective of this work is to clarify the effects of adsorption temperature on SO_(2) adsorption and desorption energy ***-based porous powdered activated coke(PPAC)prepared in the drop-tube reactor was used in this *** N_(2) adsorption measurements and Fourier transform infrared spectrometer analysis show that PPAC exhibits a developed pore structure and rich functional *** experimental results show that with a decrease in adsorption temperature in the range of 50–150℃,the adsorption capacity of SO_(2) increases linearly;meanwhile,the adsorption capacity of H_(2)O increases,resulting in the increase in desorption energy consumption per unit mass of *** processes of SO_(2) and H_(2)O desorption were determined by the temperature-programmed desorption test,and the desorption energies for each species were *** the energy consumption per unit of desorption and the total amount of adsorbent,the optimal adsorption temperature yielding the minimum total energy consumption of regeneration is *** study systematically demonstrates the effect of adsorption temperature on the adsorption–desorption process,providing a basis for energy saving and emission reduction in desulfurization system design.

关键词： Activated coke SO2 adsorption Desorption energy consumption Optimal adsorption temperature