检索结果-南通市图书馆

Increased expression of insulin-like growth factor-binding protein-3 is implicated in erectile dysfunction in two-kidney one-clip hypertensive rats after propranolol treatment

引用

Asian Journal of Andrology 2011年第6期13卷 851-855页

作者： zhang-yan zhou zhong-hua yang xing-huan wang hong cao dong chen yong-zhi wang hai-hong zhou mou peng quan-liang liu shao-ping wan Department of Urology Zhongnan Hospital of Wuhan University Wuhan 430071 China

This study aimed to investigate the role of insulin-like growth factor-binding protein-3 （IGFBP-3） in erectUe dysfunction （ED） in two-kidney one-clip （2K-1C） hypertensive rats treated with the β-blocking agent propranolol. Adult male Wistar rats were randomly divided into three groups： a normal control group, a hypertensive control group and a propranolol treatment group （n=9）. After 4 weeks of propranolol treatment, intracavemous pressure （ICP） responses to electrical stimulation of the cavernous nerves were evaluated. The expression of IGFBP-3 and insulin-like growth factor-1 （IGF-1） mRNA and protein in the rat cavernous tissue were detected by quantitative real-time PCR and Western blot, respectively. The concentration of cyclic guanosine monophosphate （cGMP） in the cavernous tissue was determined by enzyme-linked immunosorbent assay （ELISA）. Cavernosal pressure in response to cavernous nerve stimulation was decreased 4 weeks after propranolol treatment （P〈0.01, compared to the hypertensive control group）. IGFBP-3 mRNA and protein expression was increased in the propranolol treatment group compared to the hypertensive control group （P〈O.01）, whereas IGF-1 expression was decreased in the propranolol treatment group compared to the hypertensive control group （P〈0.01）. In addition, cavernous cGMP concentration was decreased in the prepranolol treatment group compared to the hypertensive control group （P〈0.01）. Taken together, these results suggest that the upregulation of IGFBP-3 may play a role in the development of ED in hypertensive rats.

关键词： erectile dysfunction insulin-like growth factor-binding protein-3 propranolol two-kidney one-clip hypertension

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nondestructive technique for identifying nuclides using neutron resonance transmission analysis at CSNS Back-n

引用

Nuclear Science and Techniques 2024年第1期35卷 178-187页

作者： Sheng-Da Tang yong-Hao chen Jing-Yu Tang Rui-Rui Fan Qiang Li Gong Li dong liu Zheng-Yao Jin xing-Zhu Cui Tian-Xiang chen Yi-Wei yang Rong liu Han Yi yang Li Zhen yang Qi An Hao-Fan Bai Jiang-Bo Bai Jie Bao ping cao Qi-ping chen Zhen chen Zeng-Qi Cui An-Chuan Fan Chang-Qing Feng Fan-Zhen Feng Ke-Qing Gao Min-Hao Gu Chang-Cai Han Zi-Jie Han Guo-Zhu He yong-cheng He yang hong Yi-Wei Hu Han-Xiong huang Wei-hua Jia Hao-yu Jiang Wei Jiang zhi-jie Jiang Ling Kang Bo Li Chao Li Jia-Wen Li Xiao Li Jie liu Shu-Bin liu Guang-Yuan Luan Chang-Jun Ning Bin-Bin Qi Jie Ren zhi-zhou Ren Xi-Chao Ruan Zhao-Hui Song Kang Sun zhi-Xin Tan Li-Jiao wang peng-cheng wang Zhao-Hui wang zhong-Wei Wen Xiao-Guang Wu Xuan Wu Li-Kun Xie yong-Ji Yu Guo-Hui zhang Lin-Hao zhang Mo-Han zhang Qi-Wei zhang Xian-peng zhang Yu-liang zhang Yue zhang zhi-yong zhang Mao-Yuan Zhao Lu-ping zhou zhi-Hao zhou Ke-Jun Zhu Sino-French Institute of Nuclear Engineering and Technology Sun Yat-sen UniversityZhuhai 519082China Institute of High-Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China USTC Archaeometry Laboratory University of Science and Technology of ChinaHefei 230026China Institute of Nuclear Physics and Chemistry China Academy of Engineering PhysicsMianyang 621900China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China

Nondestructive and noninvasive neutron assays are essential applications of neutron *** resonance transmission analysis(NRTA)is a powerful nondestructive method for investigating the elemental composition of an *** back-streaming neutron line(Back-n)is a newly built time-of-flight facility at the China Spallation Neutron Source(CSNS)that provides neutrons in the eV to 300 MeV range.A feasibility study of the NRTA method for nuclide identification was conducted at the CSNS Back-n via two test *** results demonstrate that it is feasible to identify different elements and isotopes in samples using the NRTA method at *** study reveals its potential future applications.

关键词： CSNS White neutron beam NRTA Nuclide identification Nondestructive method

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The first data release(DR1) of the LAMOST regular survey

引用

Research in Astronomy and Astrophysics 2015年第8期15卷 1095-1124页

作者： A-Li Luo yong-Heng Zhao Gang Zhao Li-Cai Deng Xiao-Wei liu Yi-peng Jing Gang wang Hao-Tong zhang Jian-Rong Shi Xiang-Qun Cui Yao-quan Chu Guo-ping Li zhong-Rui Bai Yue Wu yan Cai Shu-Yun cao Zi-huang cao Jeffrey L.Carlin hai-Yuan chen Jian-Jun chen Kun-Xin chen Li chen Xue-Lei chen Xiao-yan chen Ying chen Norbert Christlieb Jia-Ru Chu chen-zhou Cui Yi-Qiao dong Bing Du dong-Wei Fan Lei Feng Jian-Ning Fu peng Gao Xue-Fei Gong Bo-zhong Gu yan-Xin Guo Zhan-Wen Han Bo-liang He Jin-liang Hou yong-Hui Hou Wen Hou hong-Zhuan Hu Ning-Sheng Hu zhong-Wen Hu zhi-Ying Huo Lei Jia Fang-hua Jiang Xiang Jiang zhi-Bo Jiang Ge Jin Xiao Kong Xu Kong Ya-Juan Lei Ai-hua Li Chang-hua Li Guang-Wei Li hai-Ning Li Jian Li Qi Li Shuang Li Sha-Sha Li Xin-Nan Li yan Li Yin-Bi Li Ye-ping Li Yuan liang Chien-cheng Lin Chao liu Gen-Rong liu Guan-Qun liu zhi-Gang liu Wen-zhi Lu Yu Luo Yin-Dun Mao Heidi Newberg Ji-Jun Ni Zhao-Xiang Qi yong-Jun Qi Shi-Yin Shen Huo-Ming Shi Jing Song Yi-Han Song Ding-Qiang Su hong-Jun Su Zheng-hong Tang Qing-Sheng Tao Yuan Tian Dan wang Da-Qi wang Feng-Fei wang Guo-Min wang hai wang hong-Chi wang Jian wang Jia-Ning wang Jian-Ling wang Jian-ping wang Jun-Xian wang Lei wang Meng-Xin wang Shou-Guan wang Shu-Qing wang Xia wang Ya-Nan wang You wang Yue-Fei wang You-Fen wang peng Wei Ming-zhi Wei hong Wu Ke-Fei Wu Xue-Bing Wu Yu-zhong Wu Xiao-Zheng xing Ling-Zhe Xu Xin-Qi Xu yan Xu Tai-Sheng yan De-hua yang hai-Feng yang Hui-Qin yang Ming yang Zheng-Qiu Yao yong Yu Hui Yuan hai-Bo Yuan hai-Long Yuan Wei-Min Yuan Chao Zhai En-peng zhang hua-Wei zhang Jian-Nan zhang Li-Pin zhang Wei zhang yong zhang yan-Xia zhang Zheng-Chao zhang Ming Zhao Fang zhou Xu zhou Jie Zhu yong-Tian Zhu Si-cheng Zou Fang Zuo National Astronomical Observatories Chinese Academy of Sciences Department of Astronomy Peking University Shanghai Astronomical Observatory Chinese Academy of Sciences Nanjing Institute of Astronomical Optics & Technology National Astronomical ObservatoriesChinese Academy of Sciences University of Science and Technology of China Department of Physics Applied Physics and AstronomyRensselaer Polytechnic InstituteTroyNY 12180USA Department of Physics and Astronomy Earlham CollegeRichmondIN 47374USA Universitt Heidelberg Zentrum für AstronomieLandessternwarteKnigstuhl 1269117 HeidelbergGermany Department of Astronomy Beijing Normal University Yunnan Observatories Chinese Academy of Sciences Purple mountain Observatory Chinese Academy of Sciences

The Large sky Area Multi-Object Fiber Spectroscopic Telescope（LAMOST） general survey is a spectroscopic survey that will eventually cover approximately half of the celestial sphere and collect 10 million spectra of stars, galaxies and QSOs. Objects in both the pilot survey and the first year regular survey are included in the LAMOST DR1. The pilot survey started in October 2011 and ended in June 2012, and the data have been released to the public as the LAMOST Pilot Data Release in August 2012. The regular survey started in September 2012, and completed its first year of operation in June 2013. The LAMOST DR1 includes a total of 1202 plates containing 2 955 336 spectra, of which 1 790 879 spectra have observed signalto-noise ratio（SNR） ≥ 10. All data with SNR ≥ 2 are formally released as LAMOST DR1 under the LAMOST data policy. This data release contains a total of 2 204 696 spectra, of which 1 944 329 are stellar spectra, 12 082 are galaxy spectra and 5017 are quasars. The DR1 not only includes spectra, but also three stellar catalogs with measured parameters： late A,FGK-type stars with high quality spectra（1 061 918 entries）, A-type stars（100 073 entries）, and M-type stars（121 522 entries）. This paper introduces the survey design, the observational and instrumental limitations, data reduction and analysis, and some caveats. A description of the FITS structure of spectral files and parameter catalogs is also provided.

关键词： techniques: spectroscopic survey—data release—catalog

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Synergistic Effect of Triple Ion Beams on Radiation Damage in CLAM Steel

引用

Chinese Physics Letters 2014年第4期31卷 93-95页

作者： YUAN Da-Qing ZHENG yong-Nan ZUO Yi FAN ping zhou dong-Mei zhang Qiao-Li MA Xiao-Qiang CUI Bao-Qun chen Li-hua JIANG Wei-Sheng WU Yi-Can ttUANG Qun-Ying peng Lei cao xing-zhong wang Bao-Yi WEI Long ZHU Sheng-Yun China Institute of Atomic Energy Beijing 102413 Institute of Nuclear Energy Safety Technology Chinese Academy of Sciences Hefei 230031 Institute of High Energy Physics Chinese Academy of Sciences Beijing 100039

The synergistic effect of triple ion beams is investigated by simultaneous and scquential irradiations of gold, hydrogen and helium ions on the low activation martensitie steel （CLAM） developed in China. The depth profile measurements of the positron annihilation Doppler broadening S parameter are carried out as a function of slow- positron beam energy to examine the produced radiation damage. The synergistic effect of displacement damage and hydrogen and helium on the formation of radiation damage is clearly observed. In the preset case ,this effect suppresses the radiation damage in the CLAM steel due to the helium and/or hydrogen filling of vacancy clusters.

关键词： Steel Synergistic low

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A practical community-based response strategy to interrupt Ebola transmission in sierra Leone, 2014–2015

引用

Infectious Diseases of Poverty 2016年第1期5卷 670-679页

作者： zhong-Jie Li Wen-Xiao Tu Xiao-Chun wang Guo-Qing Shi Zun-dong Yin hai-Jun Su Tao Shen Da-peng zhang Jian-dong Li Shan Lv Chun-Li cao Rui-Qian Xie hong-zhou Lu Rong-Meng Jiang Zheng cao zhi-Jie An Lei-Lei Li Jie Xu yan-Wen Xiong Wei Zang Wei zhang hong-Wei zhang Wen-Sen chen hua Ling Wen Xu Jian Cai huan-Jin Luo Xue-Sheng xing Can-Jun Zheng Qiang Wei Xin-Xu Li Mei Li hai Jiang Li-quan Deng Ming-quan chen Xiang Huo Feng Xu Xue-Hui Lai Xi-chen Bai Long-Jie Ye Jian-Yi Yao Wen-Wu Yin Jiao-Jin Sun Lin Xiao Fu-Qiang liu Xiao-Qiang liu hong-Wei Fan Zeng-Qiang Kou Ji-Kun zhou Hao zhang Da-Xin Ni Thomas TSamba Qun Li hong-Jie Yu Yu wang Xiao-Feng liang Division of Infectious Disease Key Laboratory of Surveillance and Early-warning on Infectious DiseaseChinese Center for Disease Control and PreventionBeijingChina Public Health Emergency Center Chinese Center for Disease Control and PreventionBeijingChina National Center for AIDS/STD Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina Chinese Field Epidemiology Training Program Chinese Center for Disease Control and PreventionBeijingChina National Immunization Program Chinese Center for Disease Control and PreventionBeijingChina Bureau of Disease Prevention and Control National Health and Family Planning Commission of the People’s Republic of ChinaBeijingChina National Institute for Viral Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina National Institute of Parasitic Disease Chinese Center for Disease Control and PreventionShanghaiChina Chinese Center for Health Education BeijingChina Department of Infectious Diseases Shanghai Public Health Clinical CenterShanghaiChina Beijing Ditan Hospital Capital Medical UniversityBeijingChina Health News BeijingChina National Institute for Communicable Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina Department of Training Chinese Center for Health EducationBeijingChina Center for Infectious Diseases Beijing Youan HospitalCapital Medical UniversityBeijingChina Infection Management The First Affiliated Hospital of Nanjing Medical UniversityNanjingChina Chongqing Municipal Center for Disease Control and Prevention ChongqingChina Yunnan Provincial Center for Disease Control and Prevention KunmingChina Division of Infectious Disease Control and Prevention Zhejiang Provincial Center for Disease Control and PreventionHangzhouChina Guangdong Provincial Center for Disease Control and Prevention GuangzhouChina Division of Acute Infectious Disease Control and Prevention Hubei Provincial Center for Disease Control and PreventionW

Background:The Ebola virus disease spread rapidly in West Africa in 2014,leading to the loss of thousands of *** engagement was one of the key strategies to interrupt Ebola transmission,and practical community level measures needed to be explored in the field and tailored to the specific context of ***:First,community-level education on Ebola virus disease(EVD)prevention was launched for the community’s social mobilizers in six districts in Sierra Leone beginning in November ***,from January to May of 2015,in three pilot communities,local trained community members were organized to engage in implementation of EVD prevention and transmission interruption measures,by involving them in alert case report,contact tracing,and social *** epidemiological indicators of transmission interruption in three study communities were ***:A total of 6016 community social mobilizers from 185 wards were trained by holding 279 workshops in the six districts,and EVD message reached an estimated 631680 *** three pilot communities,72 EVD alert cases were reported,with 70.8%of them detected by trained local community members,and 14 EVD cases were finally *** tracing detected 64.3%of EVD *** median duration of community infectivity for the cases was 1 *** secondary attack rate was 4.2%,and no third generation of infection was *** health worker was infected,and no unsafe burial and noncompliance to EVD control measures were *** community-based measures were modeled to reduce 77 EVD cases,and the EVD-free goal was achieved four months earlier in study communities than whole country of Sierra ***: The community-based strategy of social mobilization and community engagement was effective in casedetection and reducing the extent of Ebola transmission in a country with weak health system. The successfullypractical experience to reduce the risk of Ebola transmission in the

关键词： Ebola virus disease Community engagement Health education Outbreak control

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Consensus statement on layout and delivery of automatic external defibrillator in China

引用

Journal of hainan Medical University 2020年第15期26卷 18-23页

作者： Yu cao Song chen yan-Fen Chai Xiao-Hui chen Yu-Guo chen shao-Wen cheng Wen-Wei cheng Bang-Han Ding yang Deng Jie Fu Bang-Jiang Fang Mai-Ying Fan Li Gui ping Gong Wei Guo Shu-Bin Guo liang huang Ji-Yuan Han zhong Ji Xian-Fei Ji Xin-Cai Ji hong-Xu Jin Xin-Jun Jiang wang-Xiang Jiang Jia-liang liu Xiao-Ran liu zhi liu Chuan-Zhu Lv Feng Lu Tan-Shi Li Xin Li yong Li Shang-Lun Li Shuang-Ming Li Xiao-Gang Li Bao-Jun Li Pei-Wu Li Chun-Sheng Li zhi-Jun Li Chang-Luo Li Xiang-Min Li Yin-ping Li Zong-Jun Lu Zu-Xun Lu zhong-Qiu Lu zhi-Qian Luo Xiao-xing Liao Jian-Bo Lei Tao Ma Yu Ma Yue-Feng Ma Qing-Bian Ma Lin-Hao Ma Jun-Qi Ma Shi-Nan Nie Jie-Miao Ou-yang peng peng Qiao Pei Shu-Ming Pan Guo-zhong Qing Li-Jie Qin Wu-Ying Qiao Fei shao Wei Song xing-Yue Song Zhen-Ju Song Rong-Ju Sun De-Ya Shang Du-Juan Sha Gui-Lan Tao Guo-Gang Tian Ying-ping Tian Jian-Guang Tian Chao-yang Tong Zi-Ren Tang Meng-Xiong Tang Guo-ping Wu zhi wan Tao wang Xin wang peng wang zhong wang Tong wang Ri-xing wang Yi-Xin wang Xiao-Dan wang Ling Wu Wei Wei hua Xiang Feng Xu Jun Xu Jie Xu Miao-Rong Xie Shuo-Gui Xu Tie Xu Feng Yu Wen Yi Li-Shan yang Shi-Jiao yan Jin-Jian Yao Shou-Chun yan Xue-zhong Yu Xian-zhi Ye Xian-liang yan Fu-Bing zhou Rong-Bin zhou Ming zhou Qiang zhou Jin zhou ping zhou Chang-Ju Zhu hua-dong Zhu Ji-hong Zhu hong zhang Mao zhang hua zhang Na zhang Guo-Qiang zhang Guo-Xiu zhang Jin-Song zhang Wen-Wu zhang Wen-zhong zhang Jian-Feng zhang Yi-Min Zhu Jun Zeng Yuan Zheng zhi-Jie Zheng Shen Zhao yan Zhao Min Zhao Bin Zhao Xiao-dong Zhao Xiao-Jing Zhao hong-Ke Zeng Sheng-Qiang Zou The Chinese Society of Emergency Medicine Research Unit of Island Emergency Medicine Chinese Academy of Medical SciencesHainan Medical University Key Laboratory of Emergency and Trauma of Ministry of Education Hainan Medical UniversityHaikouHainanChina Emergency and Trauma College Hainan Medical UniversityHaikouHainanChina Department of Emergency Hainan Clinical Research Center for Acute and Critical DiseasesThe Second Affiliated Hospital of Hainan Medical UniversityHaikouHainanChina Key Laboratory of hainan Trauma and Disaster Rescue Key Laboratory of Trauma of hainan Medical University

*** Sudden cardiac death(SCD)refers to sudden death due to a variety of cardiac *** is manifested as a sudden loss of consciousness,cardiac arrest,and respiratory arrest and generally shows early symptoms that are atypical and not easily detected[1].According to a recent study,nearly 544000 patients suffer from SCD every year in China[2].

关键词： cardiac death respiratory

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

薄荷醇抑制前列腺癌DU145细胞的增殖和迁移

引用

现代泌尿生殖肿瘤杂志 2012年第5期4卷 301-306页

作者：王永志王行环杨中华朱广斌陈东孟哲周章炎武汉大学中南医院泌尿外科 430071

目的探讨薄荷醇对雄激素非依赖性前列腺癌DU145细胞增殖和迁移能力的影响。方法通过RT-PCR、免疫组织化学和Western blot方法检测TRPM8和TRPA1的表达;MTT和划痕试验检测薄荷醇对DU145细胞的增殖和迁移能力的影响;流式细胞术检测TRPM8对D... 详细信息

目的探讨薄荷醇对雄激素非依赖性前列腺癌DU145细胞增殖和迁移能力的影响。方法通过RT-PCR、免疫组织化学和Western blot方法检测TRPM8和TRPA1的表达;MTT和划痕试验检测薄荷醇对DU145细胞的增殖和迁移能力的影响;流式细胞术检测TRPM8对DU145细胞周期和凋亡的影响。结果 RT-PCR、免疫组织化学和Western blot提示TRPM8在DU145细胞中高表达而TRPA1在DU145细胞中不表达;薄荷醇能诱导细胞周期阻滞于G0/G1期,与未经薄荷醇处理的细胞相比,经100μmol/L薄荷醇处理的细胞培养24、48和72h后,G0/G1期细胞显著增加(49.12%±1.92%vs61.71%±2.70%、77.65%±1.63%、71.81%±2.46%,P<0.05,P<0.01),进而抑制细胞增殖(P<0.05),并抑制细胞迁移(P<0.05),流式细胞术检测显示薄荷醇并不引起细胞凋亡。结论 TRPM8可能成为前列腺癌治疗的一个新靶点,对于高表达TRPM8的雄激素非依赖性前列腺癌针对TRPM8通道的药物治疗可能比TRPM8基因治疗更为实用,因此,薄荷醇作为一个潜在的抗肿瘤药物也拥有很大的发展前景。

关键词：薄荷醇前列腺肿瘤 DU145

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Feasibility and physics potential of detecting ^(8)B solar neutrinos at JUNO

引用

Chinese Physics C 2021年第2期45卷 93-110页

作者： Angel Abusleme Thomas Adam Shakeel Ahmad Sebastiano Aiello Muhammad Akram Nawab Ali Fengpeng An Guangpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde Marcondes de André Didier Auguste Andrej Babic wander Baldini Andrea Barresi Eric Baussan Marco Bellato Antonio Bergnoli Enrico Bernieri David Biare Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Max Buesken Mario Buscemi Jose Busto Ilya Butorov Anatael Cabrera Hao Cai Xiao Cai yanke Cai zhiyan Cai Antonio Cammi Agustin Campeny Chuanya cao Guofu cao Jun cao Rossella Caruso Cédric Cerna Jinfan Chang Yun Chang pingping chen Po-An chen shaomin chen Shenjian chen Xurong chen Yi-Wen chen Yixue chen Yu chen zhang chen Jie cheng Yaping cheng Alexander Chepurnov Davide Chiesa Pietro Chimenti Artem Chukanov Anna Chuvashova Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Salvatore Costa Flavio Dal Corso Christophe De La Taille Jiawei Deng zhi Deng Ziyan Deng Wilfried Depnering Marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Georgy Donchenko Jianmeng dong Damien Dornic Evgeny Doroshkevich Marcos Dracos Frédéric Druillole Shuxian Du Stefano Dusini Martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Lukas Fajt donghua Fan Lei Fan Can Fang Jian Fang Marco Fargetta Anna Fatkina Dmitry Fedoseev Vladko Fekete Li-cheng Feng Qichun Feng Richard Ford Andrey Formozov Amélie Fournier Haonan Gan Feng Gao Alberto Garfagnini Alexandre Göttel Christoph Genster Marco Giammarchi Agnese Giaz Nunzio Giudice Franco Giuliani Maxim Gonchar Guanghua Gong Hui Gong Oleg Gorchakov Yuri Gornushkin Marco Grassi Christian Grewing Maxim Gromov Vasily Gromov Minghao Gu Xiaofei Gu Yu Gu Mengyun Guan Nunzio Guardone Maria Gul Cong Guo Jingyuan Guo wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han yan Yerevan Physics Institute YerevanArmenia UniversitéLibre de Bruxelles BrusselsBelgium Universidade Estadual de Londrina LondrinaBrazil Pontificia Universidade Catolica do Rio de Janeiro RioBrazil Pontificia Universidad Católica de Chile SantiagoChile Universidad Tecnica Federico Santa Maria ValparaisoChile Beijing Institute of Spacecraft Environment Engineering BeijingChina Beijing Normal University BeijingChina China Institute of Atomic Energy BeijingChina Institute of High Energy Physics BeijingChina North China Electric Power University BeijingChina School of Physics Peking UniversityBeijingChina Tsinghua University BeijingChina University of Chinese Academy of Sciences BeijingChina Jilin University ChangchunChina College of Electronic Science and Engineering National University of Defense TechnologyChangshaChina Chongqing University ChongqingChina dongguan University of Technology DongguanChina Jinan University GuangzhouChina Sun Yat-Sen University GuangzhouChina Harbin Institute of Technology HarbinChina University of Science and Technology of China HefeiChina The Radiochemistry and Nuclear Chemistry Group in University of South China HengyangChina Wuyi University JiangmenChina Shandong University JinanChina Institute of Modern Physics Chinese Academy of SciencesLanzhouChina Nanjing University NanjingChina Guangxi University NanningChina East China University of Science and Technology ShanghaiChina School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghaiChina Tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghaiChina Institute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesShijiazhuangChina Nankai University TianjinChina Wuhan University WuhanChina Xi’an Jiaotong University Xi’anChina Xiamen University XiamenChina School of Physics and Microelectronics Zhengzhou UniversityZhengzhouChina Institute of Physics National Chiao-Tung University Hsinchu National United University Miao-Li Department of Physics National T

The Jiangmen Underground Neutrino Observatory(JUNO)features a 20 kt multi-purpose underground liquid scintillator sphere as its main *** of JUNO's features make it an excellent location for^8B solar neutrino measurements,such as its low-energy threshold,high energy resolution compared with water Cherenkov detectors,and much larger target mass compared with previous liquid scintillator *** this paper,we present a comprehensive assessment of JUNO's potential for detecting^8B solar neutrinos via the neutrino-electron elastic scattering process.A reduced 2 MeV threshold for the recoil electron energy is found to be achievable,assuming that the intrinsic radioactive background^(238)U and^(232)Th in the liquid scintillator can be controlled to 10^(-17)g/*** ten years of data acquisition,approximately 60,000 signal and 30,000 background events are *** large sample will enable an examination of the distortion of the recoil electron spectrum that is dominated by the neutrino flavor transformation in the dense solar matter,which will shed new light on the inconsistency between the measured electron spectra and the predictions of the standard three-flavor neutrino oscillation *** m^(2)_(21)=4.8times10^(-5);(7.5times10^(-5))eV^(2),JUNO can provide evidence of neutrino oscillation in the Earth at approximately the 3sigma(2sigma)level by measuring the non-zero signal rate variation with respect to the solar zenith ***,JUNO can simultaneously measureDelta m^2_(21)using^8B solar neutrinos to a precision of 20% or better,depending on the central value,and to sub-percent precision using reactor antineutrinos.A comparison of these two measurements from the same detector will help understand the current mild inconsistency between the value of Delta m^2_(21)reported by solar neutrino experiments and the KamLAND experiment.

关键词： neutrino oscillation solar neutrino JUNO

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Sub-percent precision measurement of neutrino oscillation parameters with JUNO

引用

Chinese Physics C 2022年第12期46卷 28-49页

作者： Angel Abusleme Thomas Adam Shakeel Ahmad Rizwan Ahmed Sebastiano Aiello Muhammad Akram Abid Aleem Fengpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde Marcondes de André Didier Auguste Weidong Bai Nikita Balashov wander Baldini Andrea Barresi Davide Basilico Eric Baussan Marco Bellato Antonio Bergnoli Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Jose Busto Ilya Butorov Anatael Cabrera Barbara Caccianiga Hao Cai Xiao Cai yanke Cai zhiyan Cai Riccardo Callegari Antonio Cammi Agustin Campeny Chuanya cao Guofu cao Jun cao Rossella Caruso Cédric Cerna Chi Chan Jinfan Chang Yun Chang Guoming chen pingping chen Po-An chen shaomin chen Xurong chen Yixue chen Yu chen zhiyuan chen Zikang chen Jie cheng Yaping cheng Yu Chin cheng Alexey Chetverikov Davide Chiesa Pietro Chimenti Artem Chukanov Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Flavio Dal Corso Olivia Dalager Christophe De La Taille zhi Deng Ziyan Deng Wilfried Depnering Marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Dmitry Dolzhikov Georgy Donchenko Jianmeng dong Evgeny Doroshkevich Marcos Dracos Frédéric Druillole Ran Du Shuxian Du Stefano Dusini Martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri donghua Fan Lei Fan Jian Fang Wenxing Fang Marco Fargetta Dmitry Fedoseev Zhengyong Fei Li-cheng Feng Qichun Feng Richard Ford Amélie Fournier Haonan Gan Feng Gao Alberto Garfagnini Arsenii Gavrikov Marco Giammarchi Nunzio Giudice Maxim Gonchar Guanghua Gong Hui Gong Yuri Gornushkin Alexandre Göttel Marco Grassi Vasily Gromov Minghao Gu Xiaofei Gu Yu Gu Mengyun Guan Yuduo Guan Nunzio Guardone Cong Guo Jingyuan Guo wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han yang Han Miao He Wei He Tobias Heinz Patrick Hellmuth Yuekun Heng Rafael Herrera YuenKeung Ho Yerevan Physics Institute YerevanArmenia UniversiéLibre de Bruxelles BrusselsBelgium Universidade Estadual de Londrina LondrinaBrazil Pontificia Universidade Catolica do Rio de Janeiro Rio de JaneiroBrazil Pontificia Universidad Católica de Chile SantiagoChile Universidad Tecnica Federico Santa Maria ValparaisoChile Beijing Institute of Spacecraft Environment Engineering BeijingChina Beijing Normal University BeijingChina China Institute of Atomic Energy BeijingChina Institute of High Energy Physics BeijingChina North China Electric Power University BeijingChina School of Physics Peking UniversityBeijingChina Tsinghua University BeijingChina University of Chinese Academy of Sciences BeijingChina Jilin University ChangchunChina College of Electronic Science and Engineering National University of Defense TechnologyChangshaChina Chongqing University ChongqingChina dongguan University of Technology DongguanChina Jinan University GuangzhouChina Sun Yat-Sen University GuangzhouChina Harbin Institute of Technology HarbinChina University of Science and Technology of China HefeiChina The Radiochemistry and Nuclear Chemistry Group in University of South China HengyangChina Wuyi University JiangmenChina Shandong University JinanChinaand Key Laboratory of Particle Physics and Particle Irradiation of Ministry of EducationShandong UniversityQingdaoChina Institute of Modern Physics Chinese Academy of SciencesLanzhouChina Nanjing University NanjingChina Guangxi University NanningChina East China University of Science and Technology ShanghaiChina School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghaiChina Tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghaiChina Institute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesShijiazhuangChina Nankai University TianjinChina Wuhan University WuhanChina Xi'an Jiaotong University Xi'anChina Xiamen University XiamenChina School of Physics and Microelectronics Zhengzhou UniversityZhengzhou

JUNO is a multi-purpose neutrino observatory under construction in the south of *** publication presents new sensitivity estimates for the measurement of the △m_(31)^(2),△m_(21)^(2),sin^(2)θ_(12),and sin^(2)θ_(13) oscillation parameters using reactor antineutrinos,which is one of the primary physics goals of the *** sensitivities are obtained using the best knowledge available to date on the location and overburden of the experimental site,the nuclear reactors in the surrounding area and beyond,the detector response uncertainties,and the reactor antineutrino spectral shape constraints expected from the TAO satellite *** is found that the △m_(21)^(2) and sin^(2)θ_(12) oscillation parameters will be determined to 0.5%precision or better in six years of data *** the same period,the △m_(31)^(2) parameter will be determined to about 0.2%precision for each mass ordering *** new precision represents approximately an order of magnitude improvement over existing constraints for these three parameters.

关键词： neutrino oscillation reactor antineutrino precision measurement JUNO

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

恶性肿瘤患者症状调查及患者日记工具可行性分析

引用

中国肿瘤 2021年第12期30卷 953-962页

作者：邹宝华吴璇李占东俞静路泽军李向敏魏星王红李全福余惠青宋正波王楠雅郭增清王文博刘勇代忠周琼赵美庆黄海力李小梅孙红曹邦伟康静波毛志远金高娃周福祥于雷杨渤彦丛明华国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院北京100021 中国人民解放军总医院北京100039 北京大学肿瘤医院北京100142 北京友谊医院北京100050 中国人民解放军海军总医院北京100048 中国人民解放军空军总医院北京100142 北京大学国际医院北京102206 北京丰台医院北京100076 鄂尔多斯市中心医院内蒙古鄂尔多斯017010 重庆市肿瘤医院重庆400030 中国科学院大学附属肿瘤医院(浙江省肿瘤医院) 中国科学院基础医学与肿瘤研究所浙江杭州310022 吉林大学白求恩第一医院吉林长春130061 福建省肿瘤医院福建福州350014 武汉大学中南医院湖北武汉430024 徐州市中心医院江苏徐州221009 北京桓兴肿瘤医院北京100023 北京三环肿瘤医院北京100023

[目的]分析肿瘤患者在入院时、住院期间及出院时的症状分布及患者日记管理工具在疾病管理中的可行性。[方法]选取全国17家医院的恶性肿瘤患者,向其发放患者日记,指导其如何填写,嘱其每日认真填写日记。通过第三方研究者问询获得并分析... 详细信息

[目的]分析肿瘤患者在入院时、住院期间及出院时的症状分布及患者日记管理工具在疾病管理中的可行性。[方法]选取全国17家医院的恶性肿瘤患者,向其发放患者日记,指导其如何填写,嘱其每日认真填写日记。通过第三方研究者问询获得并分析患者在住院时、住院期间及出院时的相关症状,通过患者对日记满意度调查与主管医生对日记认可度调查分析患者日记工具的可行性。[结果]共纳入符合要求的152例患者,调查发现肿瘤患者入院时排名前10位的症状分别是疲乏、食量下降(近1周)、疼痛、体重下降(近1个月)、睡眠不好、厌食、胸闷气短、便秘、咳嗽咳痰和心情郁闷;住院期间排名前10位的症状分别是便秘、恶心呕吐、厌食、食量下降(近1周)、腹胀、疼痛、睡眠不好、疲乏、腹泻和发热。出院时排名10位的症状分别是疲乏、便秘、睡眠不好、胸闷气短、疼痛、咳嗽咳痰、厌食、出汗、小便减少、心情郁闷。肿瘤疾病分期为Ⅳ期的患者,入院时的症状患病率明显高于非Ⅳ期患者。绝大部分患者(91.4%,139/152)认可患者日记,认为该患者日记能帮助医生更好的了解自己,65.1%(99/152)的患者表示自己出院后会继续填写该日记内容,82.2%(125/152)的患者表示填写日记不会造成负担。绝大部分主管医生(77.6%,118/152)认为患者日记设计合理,77.0%(117/152)的主管医生认可患者日记并愿意继续使用,75.7%(115/152)的主管医生认为患者日记实用性很强,72.4%(104/152)主管医生认为患者日记能够帮助自己全面了解患者症状,64.4%(98/152)的主管医生认为患者日记能够提高查房效率。[结论]Ⅳ期肿瘤患者相关症状发生率明显高于非Ⅳ期患者,需重点监测和管理。肿瘤患者临床症状在住院期间部分会得以改善,但治疗相关的不良反应使出院时症状又有升高,需要主管医生引起重视并加强出院后随访及症状管理。患者日记工具能够使患者重视肿瘤所有相关的症状的监测,能提高医护工作人员的查房效率,有助于患者及家属在出院后的疾病全程相关症状管理,值得进一步临床研究及使用。

关键词：恶性肿瘤症状患者日记简明膳食自评工具

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：