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Proximal Femur Bionic Nail (PFBN): A Panacea for Unstable Intertrochanteric Femur Fracture

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Engineering 2024年第6期37卷 152-158页

作者： Kaixuan zhang wei chen Yingze zhang School of Medicine Nankai UniversityTianjin 300071China Department of Orthopedic Surgery of Hebei Province The Third Hospital of Hebei Medical UniversityShijiazhuang 050051China Key Laboratory of Biomechanics of Hebei Province Orthopaedic Research Institute of Hebei ProvinceShijiazhuang 050051China National Health Commission(NHC)Key Laboratory of Intelligent Orthopeadic Equipment The Third Hospital of Hebei Medical UniversityShijiazhuang 050051China Chinese Academy of Engineering Beijing 100088China

With the aging population,intertrochanteric femur fracture in the elderly has become one of the most serious public health issues and a hot topic of research in trauma *** to the limitations of internal fixation techniques and the insufficient mechanical design of nails,the occurrence of complications delays patient recovery after surgical *** of a proximal femur bionic nail(PFBN)based on zhang’s N triangle theory provides triangular supporting fixation,which dramatically decreases the occurrence of complications and has been widely used for clinical treatment of unstable intertrochanteric femur fracture *** this work,we developed an equivalent biomechanical model to analyze improvement in bone remodeling of unstable intertrochanteric femur fracture through PFBN *** results show that compared with proximal femoral nail antirotation(PFNA)and InterTan,PFBN can dramatically decrease the maximum strain in the proximal *** on Frost’s mechanostat theory,the local mechanical environment in the proximal femur can be regulated into the medium overload region by using a PFBN,which may render the proximal femur in a state of physiological overload,favoring post-operative recovery of intertrochanteric femur fracture in the *** work shows that PFBN may constitute a panacea for unstable intertrochanteric femur fracture and provides insights into improving methods of internal fixation.

关键词： Intertrochanteric femur fracture Internal fixation Proximal femur bionic nail(PFBN) Biomechanics Bone remodeling

维泊妥珠单抗联合RCHP用于治疗初诊弥漫性大B细胞淋巴瘤的成本-效用

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中国药物经济学 2024年第4期19卷 17-23页

作者：梁锦莹张炜晨余美辰程国华暨南大学药学院广州511436

目的评价维泊妥珠单抗联合利妥昔单抗、环磷酰胺、多柔比星和泼尼松(PolaRCHP)用于治疗初诊弥漫性大B细胞淋巴瘤(DLBCL)患者的经济性。方法从我国卫生体系角度出发,基于PLOARIX研究构建三状态的马尔可夫(Markov)模型,对PolaRCHP方案和... 详细信息

目的评价维泊妥珠单抗联合利妥昔单抗、环磷酰胺、多柔比星和泼尼松(PolaRCHP)用于治疗初诊弥漫性大B细胞淋巴瘤(DLBCL)患者的经济性。方法从我国卫生体系角度出发,基于PLOARIX研究构建三状态的马尔可夫(Markov)模型,对PolaRCHP方案和利妥昔单抗联合环磷酰胺、多柔比星、长春新碱和泼尼松(RCHOP)方案进行成本-效用分析,模型模拟时限为患者终生,循环周期为3周,效用和成本均按5%的年贴现率进行贴现,测算总成本、健康获益和增量成本-效果比(ICER),并采用单因素敏感性分析和概率敏感性分析考察模型的稳健性。结果成本-效用分析结果显示,相比于RCHOP方案,PolaRCHP方案能使既往未经治疗的DLBCL患者增加2.70QALYs,总成本增加210134.00元,ICER值为77745.26元/QALY,低于1倍人均国内生产总值(GDP)的WTP阈值(85698元/QALY),说明PolaRCHP方案更具经济性。敏感性分析结果显示随着各变量在范围内波动,ICER值均小于3倍人均GDP。在1倍我国人均GDP的阈值下,PolaRCHP具有经济性的概率为96.45%。结论以1倍我国人均GDP为WTP阈值,从中国卫生服务体系出发,与RCHOP方案相比,PolaRCHP方案治疗既往未经治疗的DLBCL更具经济性。

关键词：弥漫性大B细胞淋巴瘤维泊妥珠单抗药物经济学成本-效用分析

高导热镁合金滤波器壳体压铸工艺、组织与性能研究

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铸造 2024年第2期73卷 194-201页

作者：周丽萍李子昕张玮宸林占宏金晨赵寿曾小勤李德江上海交通大学材料科学与工程学院轻合金精密成型国家工程研究中心上海200240 青海盐湖特立镁有限公司青海西宁811600

以Mg-4La-2Al-0.3Mn(LA42)合金为研究对象,利用OM、XCT、数值模拟等方法,对比AZ91D常规压铸工艺,优化出适用于LA42合金滤波器壳体的压铸工艺。研究表明,滤波器壳体的最优压铸工艺是浇注温度720℃、模具温度250℃、增压压力90 MPa。该工... 详细信息

以Mg-4La-2Al-0.3Mn(LA42)合金为研究对象,利用OM、XCT、数值模拟等方法,对比AZ91D常规压铸工艺,优化出适用于LA42合金滤波器壳体的压铸工艺。研究表明,滤波器壳体的最优压铸工艺是浇注温度720℃、模具温度250℃、增压压力90 MPa。该工艺下成形的滤波器壳体,其背部与散热齿的显微组织与性能相差较大。壳体背部冷却速率慢,晶粒尺寸大,伴随大量预结晶组织,而散热齿冷却速率快,晶粒尺寸细小,伴随冷隔和孔洞缺陷。散热齿热导率[107.7W/(m·K)]低于壳体背部热导率[112.3W/(m·K)]。散热齿屈服强度(170.1 MPa),远高于壳体背部屈服强度(138.4 MPa)。但散热齿区域因为含有明显冷隔和孔洞缺陷,显著影响伸长率。

关键词：镁合金热导率力学性能压铸

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Numerical simulation on the multiphase flow and reoxidation of the molten steel in a two-strand tundish during ladle change

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International Journal of Minerals,Metallurgy and Materials 2024年第7期31卷 1540-1553页

作者： Jingcheng Wang Zhentong Liu wei chen Hongliang chen Lifeng zhang School of Mechanical Engineering Yanshan UniversityQinhuangdao 066004China School of Materials Science and Engineering Tianjin UniversityTianjin 300350China School of Mechanical and Materials Engineering North China University of TechnologyBeijing 100144China

A 3D mathematical model was proposed to investigate the molten steel–slag–air multiphase flow in a two-strand slab continuous casting(CC)tundish during ladle *** study focused on the exposure of the molten steel and the subsequent reoxidation *** exposure of the molten steel was calculated using the coupled realizable k–εmodel and volume of fluid(VOF)*** diffusion of dissolved oxygen was determined by solving the user-defined scalar(UDS)***,the user-defined function(UDF)was used to describe the source term in the UDS equation and determine the oxidation rate and oxidation *** effect of the refilling speed on the molten steel exposure and dissolved oxygen content was also *** the refilling speed during ladle change reduced the refilling time and the exposure duration of the molten ***,the elevated refilling speed enlarged the slag eyes and increased the average dissolved oxygen content within the tundish,thereby exacerbating the reoxidation *** addition,the time required for the molten steel with a high dissolved oxygen content to exit the tundish varied with the refilling *** the inlet speed was 3.0 m·s^(-1)during ladle change,the molten steel with a high dissolved oxygen content exited the outlet in a short period,reaching a maximum dissolved oxygen content of 0.000525wt%.Conversely,when the inlet speed was 1.8 m·s^(-1),the maximum dissolved oxygen content was 0.000382wt%.The refilling speed during the ladle change process must be appropriately decreased to minimize reoxidation effects and enhance the steel product quality.

关键词： tundish ladle change reoxidation multiphase flow numerical simulation

Characterization of Fe-containing particles in chengdu,southwest China,using single-particle aerosol mass spectrometry

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Journal of Environmental Sciences 2024年第2期136卷 110-120页

作者： Renjiang He Junke zhang Luyao chen wei zhang Yingwei Xi School of Public Health Southwest Medical UniversityLuzhou 646000China Faculty of Geosciences and Environmental Engineering Southwest Jiaotong UniversityChengdu 611756China Sichuan Environmental Monitoring Center Chengdu 610074China

Single-particle aerosol mass spectrometry was used to study the characteristics of Fecontaining particles during winter in chengdu,southwest *** mass concentrations of PM_(2.5)and PM_(10)during the study period were 64±38 and 89±49μg/m~3,respectively,and NO_(2)and particulate matter were high compared with most other regions of *** Fecontaining particles were divided into seven categories with different mass spectra,sources and aging *** highest contribution was from Fe mixed with carbonaceous components(Fe-C,23.1%)*** was more mixed with sulfate than nitrate and therefore the contribution of Fe mixed with sulfate(Fe-S,20.7%)particles was higher than that of Fe mixed with nitrate(Fe-N,12.5%)*** contributions from Fe-containing particles related to primary combustion were high in the small particle size range,whereas aged Fecontaining particles and dust-related particles were mostly found in the coarse particle size *** air masses mainly originated from the west and east of chengdu,and the corresponding PM_(2.5)concentrations were 79±36 and 55±36μg/m~3,*** west and east air masses showed stronger contributions of Fe-containing particles related to biomass burning(Fe-B)and fossil fuel combustion(Fe-C and Fe-S)particles,*** southwest area contributed the most Fe-containing *** assessments of the effects of Fe-containing particles during heavy pollution period should pay more attention to Fe-C and Fe-S ***-reduction of Fe-containing particles should consider both local emissions and short-distance transmission from the surrounding areas.

关键词： Fe-containing particles Particle composition Potential source areas Evolution chengdu

Optimal Planning of Hybrid AC/DC Low-voltage Distribution Networks Considering DC Conversion of Three-phase Four-wire Low-voltage AC Systems

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Journal of Modern Power Systems and Clean Energy 2024年第1期12卷 141-153页

作者： Bo zhang Lu zhang wei Tang Gen Li chen Wang the College of Information and Electrical Engineering China Agricultural UniversityBeijing 100083China the Electric Energy Group Department of Engineering TechnologyTechnical University of Denmark(DTU)2750 BallerupDenmark the Power Distribution Technology Center State Grid Beijing Electric Power Research InstituteBeijing 100075China

The increasing integration of distributed household photovoltaics(PVs)and electric vehicles(EVs)may further ag gravate voltage violations and unbalance of low-voltage distribu tion networks(LVDNs).DC distribution networks can increase the accommodation of PVs and EVs and mitigate mutilple pow er quality problems by the flexible power regulation capability of voltage source *** paper proposes schemes to es tablish hybrid AC/DC LVDNs considering the conversion of the existing three-phase four-wire low-voltage AC systems to DC op *** characteristics and DC conversion constraints of typical LVDNs are *** addition,converter configura tions for typical LVDNs are proposed based on the three-phase four-wire characteristics and quantitative analysis of various DC ***,an optimal planning method of hybrid AC/DC LVDNs is proposed,which is modeled as a bi-level programming model considering the annual investments and three-phase *** are conducted to verify the effectiveness of the proposed optimal planning *** ulation results show that the proposed optimal planning method can increase the integration of PVs while simultaneously reduc ing issues related to voltage violation and unbalance.

关键词： Optimal planning low-voltage distribution net work three-phase unbalance DC conversion

QoE oriented intelligent online learning evaluation technology in B5G scenario

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Digital Communications and Networks 2024年第1期10卷 7-15页

作者： Mingzi chen Xin wei Peizhong Xie Zhe zhang School of Communications and Information Engineering Nanjing University of Posts and TelecommunicationsNanjing210003China Key Lab of Broadband Wireless Communication and Sensor Network Technology(Nanjing University of Posts and Telecommunications) Ministry of EducationNanjing210003China Institute of Higher Education Nanjing University of Posts and TelecommunicationsNanjing210003China

Students'demand for online learning has exploded during the post-COvID-19 pandemic ***,due to their poor learning experience,students'dropout rate and learning performance of online learning are not always *** technical advantages of Beyond Fifth Generation(B5G)can guarantee a good multimedia Quality of Experience(QoE).As a special case of multimedia services,online learning takes into account both the usability of the service and the cognitive development of the *** that affect the Quality of Online Learning Experience(OL-QoE)become more *** get over this dilemma,we propose a systematic scheme by integrating big data,Machine Learning(ML)technologies,and educational psychology ***,we first formulate a general definition of OL-QoE by data analysis and experimental *** formula considers both the subjective and objective factors(i.e.,video watching ratio and test scores)that most affect ***,we induce an extended layer to the classic Broad Learning System(BLS)to construct an Extended Broad Learning System(EBLS)for the students'OL-QoE *** the extended layer can increase the width of the BLS model and reduce the redundant nodes of BLS,the proposed EBLS can achieve a trade-off between the prediction accuracy and computation ***,we provide a series of early intervention suggestions for different types of students according to their predicted OL-QoE *** timely interventions,their OL-QoE and learning performance can be *** results verify the effectiveness oftheproposed scheme.

关键词： B5G Online learning Quality of experience

Homogenization heat treatment for an additively manufactured precipitation-hardening high-entropy alloy

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Rare Metals 2022年第8期41卷 2853-2863页

作者： Zhi-Yuan Liu Xin-Yi Zhao Yao-Wen Wu Qiang chen Bao-Hua Yang Pei Wang zhang-wei chen Can Yang Additive Manufacturing Institute College of Mechatronics and Control EngineeringShenzhen UniversityShenzhen518060China Sino-German College of Intelligent Manufacturing Shenzhen Technology UniversityShenzhen518118China

A precipitation-hardening high-entropy alloy(HEA),(FeCoNi)_(86)Al_(7) Ti_(7),was successfully fabricated using selective laser melting(SLM).Severe segregation of Ti occurred at the boundaries of dislocation ***,homogenization heat treatment at 1150℃for 0.5 h was performed to alleviate the *** homogenization,almost no dislocation cells were left in the grains,and recrystallization occurred as the average grain size increased from 37 to 54μ*** with the initial as-built HEA,the ductility of the HEA increases significantly from 29%to 40%,and the strength decreases slightly from 710 to 606 *** further aging,pre-homogenization can decrease the precipitation of ordered L2_(1) *** void has a high propensity to initiate from the matrix/L2_(1) incoherent interface,pre-homogenization reduced the number of weak points,thus considerably improving the plastic deformation ability of the aged HEA by 36%.In addition,the strengthening mechanism has also been analyzed for the aged *** was revealed that the coherent L1_(2)precipitate contributed the most to the increased strength.

关键词： High-entropy alloy Selective laser melting Homogenization heat treatment Strengthening mechanism

Thin paints for durable and scalable radiative cooling

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Journal of Energy Chemistry 2024年第3期90卷 176-182,I0006页

作者： Shanquan Liu Fei zhang Xingyu chen Hongjie Yan wei chen Meijie chen School of Energy Science and Engineering Central South UniversityChangsha 410083HunanChina School of Intelligent Manufacturing Ecosystem Xi'an Jiaotong-Liverpool UniversitySuzhou 215400JiangsuChina

Passive daytime radiative cooling(PDRC) is environment-friendly without energy input by enhancing the coating's solar reflectance(R_(solar)) and thermal emittance(ε_(LWIR)) in the atmosphere's long-wave infrared transmission ***,high R_(solar) is usually achieved by increasing the coating's thickness,which not only increases materials' cost but also impairs heat ***,the desired high R_(solar) is vulnerable to dust pollution in the *** this work,a thin paint was designed by mixing hBN plates,PFOTS,and IPA. R_(solar)=0.963 and ε_(LWIR)=0.927 was achieved at a thickness of 150 μm due to the high backscattering ability of scatters.A high through-plane thermal conductivity(~1.82 W m^(-1) K^(-1)) also can be *** addition,the porous structure coupled with the binder PFOTS resulted in a contact angle of 154°,demonstrating excellent durability under dust *** experiments showed that the thin paint can obtain a 2.3℃ lower temperature for sub-ambient cooling than the reference PDRC coating in the ***,the above-ambient heat dissipation performance can be enhanced by spraying the thin paint on a 3D heat sink,which was 15.7℃ lower than the reference 1D structure,demonstrating excellent performance for durable and scalable PDRC applications.

关键词： Radiative cooling Heat dissipation Solar reflectance Thermal emittance Contact angle