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Tectonic Evolution and Geological Characteristics of Hydrocarbon Reservoirs in Marine Mesozoic-Paleozoic Strata in the South Yellow Sea Basin

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Journal of Ocean University of China 2018年第5期17卷 1075-1090页

作者： YUAN Yong CHEN Jianwen zhang yuxi LIANG Jie zhang Yinguo zhang Penghui Qingdao Institute of Marine Geology Qingdao 266071China Laboratory for Marine Mineral Resources Qingdao National Laboratory for Marine Science and TechnologyQingdao 266071China Faculty of Earth Resources China University of GeosciencesWuhan 430074China College of Oceanography Hohai UniversityNanjing 210098China

The South Yellow Sea Basin is the main body of the lower Yangtze area in which marine Mesozoic–Paleozoic strata are widely *** latest geophysical data were used to overcome the limitation of previous poor-quality deep ***,the geological characteristics of hydrocarbon reservoirs in the marine Mesozoic–Paleozoic strata in the South Yellow Sea Basin were analyzed by comparing the source rocks and the reservoir and utilizing drilling and outcrop *** is believed that the South Yellow Sea Basin roughly underwent six evolutionary stages:plate spreading,plate convergence,stable platform development,foreland basin development,faulted basin development,and depression basin *** South Yellow Sea Basin has characteristics of a composite platform-fault depression geological structure,with a half-graben geological structure and with a ‘sandwich structure' in the vertical *** sets of hydrocarbon source rocks developed – the upper Permian Longtan–Dalong formation,the lower Permian Qixia formation,the lower Silurian Gaojiabian formation,and the lower Cambrian Hetang formation/Mufushan formation,giving the South Yellow Sea Basin relatively good hydrocarbon *** carbonate is the main reservoir rock type in the South Yellow Sea area,and there are four carbonate reservoir types:porous dolomitic,reef-bank,weathered crust,and *** are reservoir-forming horizons similar to the typical hydrocarbon reservoirs in the Yangtze land area developed in the South Yellow Sea,and there are three sets of complete source-reservoir-cap rock assemblages developed in the marine strata,with very good hydrocarbon potential.

关键词：中生代古生代南方水库海盆地质海洋特征

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Unveiling non-radiative center control in CsPbBr_(3) nanocrystals:A comprehensive comparative analysis of hot injection and ligandassisted reprecipitation approaches

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Nano Research 2024年第5期17卷 4525-4534页

作者： Daocheng Hong Yuchen zhang Shuhan Pan Hanyu Liu Wei Mao Wanli zhang Yuhui Ye Zhihong Wei Xuxing Lu Xiaoyong Wang Zhenda Lu yuxi Tian Key Laboratory for Advanced Technology in Environmental Protection of Jiangsu Province Yancheng Institute of TechnologyYancheng 224051China Laboratory of Mesoscopic Chemistry of MOE School of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023China College of Engineering and Applied Sciences Nanjing UniversityNanjing 210023China National Laboratory of Solid State Microstructures School of PhysicsCollaborative Innovation Center of Advanced MicrostructuresNanjing UniversityNanjing 210093China School of Electronic Electrical Engineering and PhysicsFujian University of TechnologyFuzhou 350118China

Metal-halide perovskite nanocrystals(NCs)have gained significant attention in the field of optoelectronic and photonic devices due to their promising *** their exceptional optical properties,the impact of different synthetic strategies on the fundamental nature of NCs,such as nonradiative recombination centers,remains poorly *** this study,we investigated the photophysical properties of CsPbBr_(3) NCs synthesized using two distinct methods,hot injection and ligand-assisted reprecipitation,at the individual particle *** observed different blinking behaviors under specific photoexcitation power densities and proposed,through intensity-lifetime analysis and Monte-Carlo simulations,that these different synthetic strategies can fabricate NCs with similar crystal structures but distinct surface quenchers with varying energy levels,which significantly affected the photo-induced blinking-down and blinking-up behaviors in individual *** findings indicate a practical and feasible approach for controlling defect engineering in perovskite NCs,with significant implications for their use in optoelectronic and other technological applications.

关键词： metal-halide perovskite nanocrystals photophysical properties nonradiative recombination centers hot injection method ligand-assisted reprecipitation

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BMP9 induces osteogenic differentiation through up-regulating LGR4 via the mTORC1/ Stat3 pathway in mesenchymal stem cells

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Genes & Diseases 2024年第3期11卷 468-483页

作者： Jie zhang Jinhai Jiang Hang Liu Shiyu Wang Kaixin Ke Siyuan Liu Yue Jiang Lu Liu Xiang Gao Baicheng He yuxi Su Department of Pharmacology School of PharmacyChongqing Medical UniversityChongqing 400016China Key Laboratory of Biochemistry and Molecular Pharmacology of Chongqing Chongqing Medical UniversityChongqing 400016China Department of Orthopedics Second Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China orthopedics Department Children's Hospital of Chongqing Medical UniversityChongqing 400014China China International Science and Technology Cooperation Base of Child Development and Critical Disorders Jiangxi Hospital Affiliated Children's Hospital of Chongqing Medical UniversityJiangxi 330000China National Clinical Research Center for Child Health and Disorders China

Bone defects and non-union are prevalent in clinical orthopedy,and the outcomes of current treatments are often *** tissue engineering offers a promising approach to treating these conditions *** morphogenetic protein 9(BMP9)can commit mesenchymal stem cells to osteogenic lineage,and a knowledge of the underlying mechanisms may help advance the field of bone tissue ***-rich repeats con-taining G protein-coupled receptor 4(LGR4),a member of G protein-coupled receptors,is essential for modulating bone *** study is aimed at investigating the impact of LGR4 on BMP9-induced osteogenesis in mesenchymal stem cells as well as the underlying *** marrow stromal cells from BMp9-knockout mice exhibited diminished LGR4 expression,and exogenous LGR4 clearly restored the impaired osteogenic potency of the bone marrow stromal ***,LGR4 expression was increased by BMP9 in C3H10T1/2 ***4 augmented the benefits of BMP9-induced osteogenic markers and bone formation,whereas LGR4 inhibition restricted these ***,the BMP9-induced li-pogenic markers were increased by LGR4 *** protein levels of Raptor and p-Stat3 were elevated by *** knockdown or p-Stat3 suppression attenuated the osteoblastic markers and LGR4 expression brought on by ***4 significantly reversed the blocking ef-fect of Raptor knockdown or p-Stat3 suppression on the BMP9-induced osteoblastic *** interacts with p-Stat3,and p-Stat3 activates the LGR4 promoter *** conclusion,LGR4 boosts BMP9 osteoblastic potency in mesenchymal stem cells,and BMP9 may up-regulate LGR4 via the mTORC1/Stat3 signal activation.

关键词： BMP9 LGR4 mTORC1 Osteogenic differentiation Stat3

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Coupling of Adhesion and Anti‑Freezing Properties in Hydrogel Electrolytes for Low‑Temperature Aqueous‑Based Hybrid Capacitors

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Nano-Micro Letters 2024年第2期16卷 15-31页

作者： Jingya Nan Yue Sun Fusheng Yang Yijing zhang yuxi Li Zihao Wang Chuchu Wang Dingkun Wang Fuxiang Chu Chunpeng Wang Tianyu Zhu Jianchun Jiang Institute of Chemical Industry of Forest Products Chinese Academy of ForestryKey Laboratory of Biomass Energy and MaterialJiangsu ProvinceNanjing 210042JiangsuPeople’s Republic of China Co‑Innovation Center of Efficient Processing and Utilization of Forest Resources Nanjing Forestry UniversityNanjing 210037JiangsuPeople’s Republic of China Energy Technologies Area Lawrence Berkeley National LaboratoryBerkeleyCA 94720USA Department of Materials Science and Engineering Clemson UniversityClemsonSC 29634USA

Solid-state zinc-ion capacitors are emerging as promising candidates for large-scale energy storage owing to improved safety,mechanical and thermal stability and easy-to-direct *** electrolytes are appealing solid-state electrolytes because of eco-friendliness,high conductivity and intrinsic ***,the electrolyte/electrode interfacial contact and anti-freezing properties of current hydrogel electrolytes are still challenging for practical applications of zinc-ion ***,we report a class of hydrogel electrolytes that couple high interfacial adhesion and anti-freezing *** synergy of tough hydrogel matrix and chemical anchorage enables a well-adhered interface between hydrogel electrolyte and ***,the cooperative solvation of ZnCl2 and LiCl hybrid salts renders the hydrogel electrolyte high ionic conductivity and mechanical elasticity simultaneously at low *** significantly,the Zn||carbon nanotubes hybrid capacitor based on this hydrogel electrolyte exhibits low-temperature capacitive performance,delivering high-energy density of 39 Wh kg^(-1)at-60°C with capacity retention of 98.7%over 10,000 *** the benefits of the well-adhered electrolyte/electrode interface and the anti-freezing hydrogel electrolyte,the Zn/Li hybrid capacitor is able to accommodate dynamic deformations and function well under 1000 tension cycles even at-60°*** work provides a powerful strategy for enabling stable operation of low-temperature zinc-ion capacitors.

关键词： Interfacial adhesion Anti-freezing Hydrogel electrolytes Low-temperature hybrid capacitors Dynamic deformati

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Development of an Integrated Disposable Device for SARSCoV-2 Nucleic Acid Extraction and Detection

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Biomedical and Environmental Sciences 2024年第6期37卷 639-646页

作者： Jing Ma Yanzhe Hao Meiling Hou Xiaoshan zhang Jingduan Liu Haodi Meng Jiangbo Chang Xuejun Ma Jihua Liu Qingjie Ying Xianhua Wang Hongxia Li yuxi Cao Xiaoguang zhang National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases National Institute for Viral Disease Control and PreventionChinese Center for Disease Control and PreventionBeijing 102206China Beijing Runbio Biotechnology Development Co. LtdBeijing 100106China Beijing Beta Technology Co. LtdBeijing 101318China Jiangsu Qitian Gene Biotechnology Co. LtdWuxi 214135JiangsuChina

Objective To develop a highly sensitive and rapid nucleic acid detection method for the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).Methods We designed,developed,and manufactured an integrated disposable device for SARS-CoV-2 nucleic acid extraction and *** precision of the liquid transfer and temperature control was tested.A comparison between our device and a commercial kit for SARS-Cov-2 nucleic acid extraction was performed using real-time fluorescence reverse transcription polymerase chain reaction(RT-PCR).The entire process,from SARS-CoV-2 nucleic acid extraction to amplification,was *** The precision of the syringe transfer volume was 19.2±1.9μL(set value was 20),32.2±1.6(set value was 30),and 57.2±3.5(set value was 60).Temperature control in the amplification tube was measured at 60.0±0.0℃(set value was 60)and 95.1±0.2℃(set value was 95)***-Cov-2 nucleic acid extraction yield through the device was 7.10×10^(6) copies/mL,while a commercial kit yielded 2.98×10^(6) copies/*** mean time to complete the entire assay,from SARS-CoV-2 nucleic acid extraction to amplification detection,was 36 min and 45 *** detection limit for SARS-CoV-2 nucleic acid was 250 copies/*** The integrated disposable devices may be used for SARS-CoV-2 Point-of-Care test(POCT).

关键词： An integrated disposable device SARS-Cov-2 Nucleic acid detection

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小儿ECMO脑损伤的特点及监测

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中华小儿外科杂志 2023年第5期44卷 450-458页

作者：张玉喜莫绪明南京医科大学附属儿童医院心胸外科南京210008

随着体外膜氧合(extracorporeal membrane oxygenation,ECMO)设备和技术的不断进步,ECMO在婴幼儿疾病谱中的适应证越来越广泛。虽然ECMO显著提高了患儿生存率,但它与大量并发症相关,其中脑损伤是最主要、最严重的并发症,其发生率为8%~20... 详细信息

随着体外膜氧合(extracorporeal membrane oxygenation,ECMO)设备和技术的不断进步,ECMO在婴幼儿疾病谱中的适应证越来越广泛。虽然ECMO显著提高了患儿生存率,但它与大量并发症相关,其中脑损伤是最主要、最严重的并发症,其发生率为8%~20%。本文就小儿ECMO中脑损伤的特点、脑功能的监测手段等做一综述,以期为临床治疗提供参考。

关键词：体外膜氧合作用脑损伤儿童 ECMO

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PsRGL1 negatively regulates chilling- and gibberellin-induced dormancy release by PsF-box1-mediated targeting for proteolytic degradation in tree peony

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Horticulture Research 2023年第5期10卷 49-60页

作者： Linqiang Gao Demei Niu Tianyu Chi Yanchao Yuan Chunying Liu Shupeng Gai yuxi zhang College of Life Sciences Qingdao Agricultural UniversityQingdao 266109China University Key Laboratory of Plant Biotechnology in Shandong Province Qingdao 266109China

Tree peony bud endodormancy is a common survival strategy similar to many perennial woody plants in winter,and the activation of the GA signaling pathway is the key to breaking *** signal transduction is involved in many physiological *** the GA-GID1-DELLA regulatory module is conserved in many plants,it has a set of specific components that add complexity to the GA response *** proteins are key switches in GA ***,there is an urgent need to identify the key DELLA proteins involved in tree peony bud dormancy *** this study,the prolonged chilling increased the content of endogenously active ***1 among three DELLA proteins was significantly downregulated during chilling-and exogenous GA3-induced bud dormancy release by cell-free degradation assay,and a high level of polyubiquitination was *** PsRGL1 accelerated bud dormancy release by increasing the expression of the genes associated with dormancy release,including PsCYCD,PsEBB1,PsEBB3,PsBG6,and *** F-box protein family members responded to chilling and GA3 treatments,resulting in PsF-box1 *** two-hybrid and BiFC assays indicated that only PsF-box1 could bind to PsRGL1,and the binding site was in the C-terminal ***-box1 overexpression promoted dormancy release and upregulated the expression of the dormancy-related *** addition,yeast two-hybrid and pull-down assays showed that PsF-box1 also interacted with PsSKP1 to form an E3 ubiquitin *** findings enriched the molecular mechanism of the GA signaling pathway during dormancy release,and enhanced the understanding of tree peony bud endodormancy.

关键词： release tree breaking

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Unveiling blood pressure-associated genes in aortic cells through integrative analysis of GWAS and RNA modification-associated variants

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Chronic Diseases and Translational Medicine 2024年第2期10卷 118-129页

作者： Huan zhang yuxi Chen Peng Xu Dan Liu Naqiong Wu Laiyuan Wang Xingbo Mo Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases Department of EpidemiologySchool of Public HealthMedical College of Soochow UniversitySuzhouJiangsuChina Cardiometabolic Center Fuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Key Laboratory of Cardiovascular Epidemiology&Department of Epidemiology State Key Laboratory of Cardiovascular DiseaseFuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina MOE Key Laboratory of Geriatric Diseases and Immunology School of Public HealthCenter for Genetic Epidemiology and GenomicsMedical College of Soochow UniversitySuzhouJiangsuChina

Background Genome-wide association studies(GWAS)have identified more than a thousand loci for blood pressure(BP).Functional genes in these loci are cell-type *** aim of this study was to elucidate potentially functional genes associated with BP in the aorta through the utilization of RNA modification-associated single-nucleotide polymorphisms(RNAm-SNPs).Methods Utilizing large-scale genetic data of 757,601 individuals from the UK Biobank and International Consortium of Blood Pressure consortium,we identified associations between RNAm-SNPs and *** association between RNAm-SNPs,gene expression,and BP were *** A total of 355 RNAm-SNPs related to m6A,m1A,m5C,m7G,and A-to-I modification were associated with *** related genes were enriched in the pancreatic secretion pathway and renin secretion *** BP GWAS signals were significantly enriched with m6A-SNPs,highlighting the potential functional relevance of m6A in physiological processes influencing ***,m6A-SNPs in CYP11B1,PDE3B,HDAC7,ACE,SLC4A7,PDE1A,FRK,MTHFR,NPPA,CACNA1D,and HDAC9 were *** methylation and differential expression of the BP genes in FTO-overexpression and METTL14-knockdown vascular smooth muscle cells were ***-SNPs were associated with ascending and descending aorta diameter and the genes showed differential methylation between aortic dissection(AD)cases and *** scRNA-seq study,we identified ARID5A,HLA-DPB1,HLA-DRA,IRF1,LINC01091,MCL1,MLF1,MLXIPL,NAA16,NADK,RERG,SRM,and USP53 as differential expression genes for AD in aortic *** The present study identified RNAm-SNPs in BP loci and elucidated the associations between the RNAm-SNPs,gene expression,and *** identified BP-associated genes in aortic cells were associated with AD.

关键词： aortic dissection blood pressure genome-wide association study RNA modification single-cell

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Hydrocarbon Geological Conditions and Exploration Potential of Mesozoic–Paleozoic Marine Strata in the South Yellow Sea Basin

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Journal of Ocean University of China 2019年第6期18卷 1329-1343页

作者： YUAN Yong CHEN Jianwen LIANG Jie XU Ming LEI Baohua zhang yuxi CHENG Qingsong WANG Jianqiang Qingdao Institute of Marine Geology China Geological SurveyQingdao 266071China Laboratory for Marine Mineral Resources Qingdao National Laboratory for Marine Science and TechnologyQingdao 266071China Faculty of Earth Resources China University of GeosciencesWuhan 430074China College of Resources and Environment Yangtze UniversityWuhan 430100China

No substantial breakthroughs have been made in hydrocarbon exploration of the South Yellow Sea *** is believed that the Mesozoic-Paleozoic marine sedimentary formation in the South Yellow Sea Basin is similar to that in the Sichuan ***,outcrop,drilling,and seismic data were determined and compared with the research results on petroleum geological conditions in the Yangtze land area,and the hydrocarbon geological conditions were analyzed comprehensively from multiple aspects,such as basin evolution and main source rocks,reservoir characteristics,preservation conditions,and structural *** results show that two main stages in the South Yellow Sea Basin(the stable evolution stage of the Mesozoic-Paleozoic marine basin and the Mesozoic-Cenozoic tectonic reformation and basin formation stage)were important for the development and evolution of four sets of main source *** dominated by carbonate rocks,three sets of capping beds with good sealing capability,relatively weak magmatic activity,and multiple types of structural traps jointly constituted relatively good hydrocarbon-reservoir-forming *** were four sets of main source-reservoir-cap assemblages and three possible hydrocarbon reservoir types(primary residual-type hydrocarbon reservoir,shallow reformed-type hydrocarbon reservoir,and composite-type hydrocarbon reservoir)developed in the marine *** is concluded that the marine strata in the South Yellow Sea Basin have relatively good hydrocarbon *** Laoshan Uplift is characterized by stable structure,complete preserved source reservoir cap assemblage,and large structural traps,and thus it is the preferred prospect zone for marine Paleozoic hydrocarbon exploration in this area.

关键词： hydrocarbon geological conditions exploration potential marine Mesozoic-Paleozoic strata South Yellow Sea Basin

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Experimental observation of multiple topological nodal structure in LaSb_(2)

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Science China(Physics,Mechanics & Astronomy) 2024年第4期67卷 138-145页

作者： yuxi Qiao Fuyi Wang Huaiqiang Wang Zicheng Tao Zhicheng Jiang Zhengtai Liu Soohyun Cho Fayuan zhang Qingkai Meng Wei Xia Yichen Yang Zhe Huang Jishan Liu Zhonghao Liu Zengwei Zhu Shan Qiao Yanfeng Guo Haijun zhang Dawei Shen State Key Laboratory of Functional Materials for Informatics Shanghai Institute of Microsystem and Information TechnologyChinese Academy of SciencesShanghai 200050China National Synchrotron Radiation Laboratory and School of Nuclear Science and TechnologyUniversity of Science and Technology of ChinaHefei 230026China National Laboratory of Solid State Microstructures School of PhysicsNanjing UniversityNanjing 210093China School of Physics and Technology Nanjing Normal UniversityNanjing 210023China School of Physical Science and Technology ShanghaiTech UniversityShanghai 201210China Shanghai Synchrotron Radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghai 201210China Shenzhen Institute for Quantum Science and Engineering Southern University of Science and TechnologyShenzhen 518055China Wuhan National High Magnetic Field Center and School of Physics Huazhong University of Science and TechnologyWuhan 430074China ShanghaiTech Laboratory for Topological Physics ShanghaiTech UniversityShanghai 201210China Institute of High-Pressure Physics School of Physical Science and Technology Ningbo UniversityNingbo 315211China Collaborative Innovation Center of Advanced Microstructures Nanjing UniversityNanjing 210093China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China

Unconventional fermions in the immensely studied topological semimetals are the source for rich exotic topological ***,using symmetry analysis and first-principles calculations,we propose the coexistence of multiple topological nodal structure in LaSb_(2),including topological nodal surfaces,nodal lines and in particular eightfold degenerate nodal points,which have been scarcely observed in a single ***,utilizing angle-resolved photoemission spectroscopy,we confirm the existence of nodal surfaces and eightfold degenerate nodal points in LaSb_(2).The intriguing multiple topological nodal structure might play a crucial role in giving rise to the large linear *** work renews the insights into the exotic topological phenomena in LaSb_(2).

关键词： eightfold degenerate points multiple topological nodal structure angle-resolved photoemission spectroscopy linear unsaturated magnetoresistance

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