检索结果-南通市图书馆

聚番红花红-纳米金复合膜修饰电极对鸟嘌呤的测定及应用研究

在线全文

学校读者我要写书评

暂无评论

化学研究与应用 2014年第1期26卷 38-42页

作者：牛凌梅张玉娜连靠奇石红梅徐秀娟河北医科大学公共卫生学院河北石家庄050017 河北医科大学第四医院内分泌科河北石家庄050011 河北医科大学口腔医学院河北石家庄050017

制备了聚番红花红-纳米金复合膜修饰的玻碳电极并用扫描电镜及交流阻抗进行了表征。利用差分脉冲法（ DPV）研究了鸟嘌呤在此修饰电极上的电化学行为。结果表明聚番红花红-纳米金复合膜对于鸟嘌呤的氧化能够起到明显的电催化作用。在优... 详细信息

制备了聚番红花红-纳米金复合膜修饰的玻碳电极并用扫描电镜及交流阻抗进行了表征。利用差分脉冲法（ DPV）研究了鸟嘌呤在此修饰电极上的电化学行为。结果表明聚番红花红-纳米金复合膜对于鸟嘌呤的氧化能够起到明显的电催化作用。在优化条件下，鸟嘌呤的氧化峰电流与其浓度在6．0x10-7-7．0x10-5 mol.L-1范围内呈良好的线性关系，检出限为8．0x10-8 mol.L-1。该方法快速，准确，将聚番红花红-纳米金复合膜修饰电极用于实际样品的测定，结果满意。

关键词：聚番红花红纳米金玻碳电极鸟嘌呤 poly( safranine T)

Pulp health and calcific healing of a complicated crown–root fracture with additional root fracture in a maxillary incisor: A case report

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2025年第3期13卷 42-49页

作者： na Li yue-yue Ren Ying Tang Qi Yang Tian-Tian Meng Song Li Jing zhang Stomatological Hospital and College Anhui Medical UniversityHefei 230032Anhui ProvinceChina Department of Endodontics The Affiliated Stomatological Hospital of Xuzhou Medical UniversityXuzhou 221000Jiangsu ProvinceChina

BACKGROUND Complicated crown–root fracture (CRF) involves severe injury to the crown, root,and pulp, and may be accompanied by multiple root fractures. The loss of a toothhas lifelong consequences for children and teenagers, but the maintenance of pulphealth and the calcific healing of multiple root fractures are rarely reported in *** SUMMARY This case reports healing of a permanent tooth with complicated crown–root andadditional root fractures, in which pulp health was maintained. A 10-year-old girlfell and fractured the root of her maxillary left central incisor at the cervical *** the coronal fragment was repositioned, the tooth was splinted until thetooth was no longer mobile, 2 years later. Eight years after treatment, the toothhas remained asymptomatic with vital pulp and localized gingival ***-beam computed tomography revealed not only calcified healing of the CRFbut also spontaneous healing in an additional undiagnosed root fracture. Thefracture line on the enamel could not be healed by hard tissue and formed agroove in the cervical crown. It was speculated that the groove was related to thelocalized gingival *** This case provides a clinical perspective of the treatment of a tooth with acomplicated CRF and an additional root fracture.

关键词： Complicated crown-root fracture Multiple root fracture Spontaneous healing Cone-beam computed tomography Long-term follow-up Case report

吡咯烷二硫代氨基甲酸酯对2型糖尿病大鼠心肌的保护作用

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国病理生理杂志 2011年第6期27卷 1149-1153页

作者：朱铁年刘建坤刘桂红张玉娜张利众赵瑞景中国人民解放军白求恩国际和平医院肿瘤科河北石家庄050082 河北医科大学第四医院内分泌科河北石家庄050011 河北医科大学免疫学教研室河北石家庄050017

目的:探讨吡咯烷二硫代氨基甲酸酯(PDTC)的降糖作用及对糖尿病大鼠心肌的保护作用。方法:37只雄性Wistar大鼠,随机分为正常对照组(NC)和高脂饮食组(HFD)。喂养8周后,高脂饮食组大鼠腹腔注射单剂量链脲佐菌素(STZ)27 mg/kg复制2型糖尿病... 详细信息

目的:探讨吡咯烷二硫代氨基甲酸酯(PDTC)的降糖作用及对糖尿病大鼠心肌的保护作用。方法:37只雄性Wistar大鼠,随机分为正常对照组(NC)和高脂饮食组(HFD)。喂养8周后,高脂饮食组大鼠腹腔注射单剂量链脲佐菌素(STZ)27 mg/kg复制2型糖尿病大鼠模型。造模成功后再随机分为模型组和PDTC治疗组。PDTC治疗组大鼠每天腹腔注射PDTC(50 mg/kg)1次,模型组和正常对照组每天注射相同剂量的生理盐水,连续注射1周后,检测血糖及各种生化指标,处死大鼠。检测心肌组织中丙二醛(MDA)含量、超氧化物歧化酶(SOD)和谷胱甘肽过氧化物酶(GSH-Px)的活性;用透射电镜观察心肌组织的超微结构;用免疫组化观察心肌组织中诱导型一氧化氮合酶(iNOS)和硝基酪氨酸(NT)的表达。结果:糖尿病模型组与正常对照组大鼠相比,血糖和MDA水平显著升高,SOD和GSH-Px活性明显下降(P<0.01);PDTC治疗后,血糖和MDA水平明显降低,SOD和GSH-Px活性明显升高(P<0.01)。糖尿病组心肌变性坏死、线粒体损伤及炎症细胞浸润;PDTC治疗后线粒体损伤明显减轻。糖尿病组较正常对照组心肌中iNOS和NT的表达均明显增加;PDTC治疗后iNOS和NT的表达均明显减少。结论:高血糖可引起氧化应激,使心肌组织中iNOS和NT生成过多,损伤了心肌细胞的结构和功能。PDTC不仅具有降糖作用,而且还可以通过减少iNOS和NT的产生,进而阻止或延缓糖尿病心肌病的发生。

关键词：糖尿病心肌病吡咯烷二硫代氨基甲酸酯氧化性应激一氧化氮合酶硝基酪氨酸

Partial Linear Model Averaging Prediction for Longitudinal Data

在线全文

学校读者我要写书评

暂无评论

Journal of Systems Science & Complexity 2024年第2期37卷 863-885页

作者： LI na FEI yu zhang Xinyu Faculty of Science Kunming University of Science and TechnologyKunming 650500China School of Statistics and Mathematics Yunnan University of Finance and EconomicsKunming 650221China Academy of Mathematics and Systems Science Chinese Academy of SciencesBeijing 100190China

Prediction plays an important role in data *** averaging method generally provides better prediction than using any of its *** though model averaging has been extensively investigated under independent errors,few authors have considered model averaging for semiparametric models with correlated *** this paper,the authors offer an optimal model averaging method to improve the prediction in partially linear model for longitudinal *** model averaging weights are obtained by minimizing criterion,which is an unbiased estimator of the expected in-sample squared error loss plus a *** properties,including asymptotic optimality and consistency of averaging weights,are established under two scenarios:(i)All candidate models are misspecified;(ii)Correct models are available in the candidate *** studies and an empirical example show that the promise of the proposed procedure over other competitive methods.

关键词： Asymptotic optimality longitudinal data model averaging estimator partially linear model prediction

颅内巨大动脉瘤行颅内外动脉搭桥术的手术配合

在线全文

学校读者我要写书评

暂无评论

中国实用护理杂志 2017年第18期33卷 1381-1383页

作者：金鑫郎红娟李娟张娜于嘉第四军医大学唐都医院护理部西安710038 第四军医大学唐都医院神经外科手术室西安710038 第四军医大学唐都医院神经外科西安710038

目的探讨行颅内外动脉搭桥术治疗颅内巨大动脉瘤手术的配合方法.方法回顾2014年10月至2016年6月进行的7例颅内外动脉搭桥术治疗颅内巨大动脉瘤的病历,分析术前、术中各项手术配合的护理要点.结果术后全部患者常规进行全脑血管造影检... 详细信息

目的探讨行颅内外动脉搭桥术治疗颅内巨大动脉瘤手术的配合方法.方法回顾2014年10月至2016年6月进行的7例颅内外动脉搭桥术治疗颅内巨大动脉瘤的病历,分析术前、术中各项手术配合的护理要点.结果术后全部患者常规进行全脑血管造影检查提示搭桥血管通畅良好,无围手术期护理并发症.结论加强多切口管理、主动体温干预、特殊仪器设备的使用和预防血栓形成是配合手术成功的护理要点.

关键词：颅内外动脉搭桥术手术配合护理要点

Catalytic atroposelective synthesis of indolyl quinazolinones bearing N-N/C-C diaxes

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2025年

作者： Ning-Yi Wang Shuo Gao Zhu-Di Shu Bei-Bei Cheng Chun Ma yu-Chen zhang Feng Shi Research Center of Chiral Functional Heterocycles School of Chemistry and Materials Science Jiangsu Normal University School of Petrochemical Engineering Changzhou University School of Chemistry and Chemical Engineering Henan Normal University

The first catalytic atroposelective synthesis of indole derivatives bearing N-N/C-C diaxes has been established by the strategy of de novo ring formation. By this strategy, various indolyl quinazolinones bearing vicinal N-N/C-C diaxes were synthesized in high yields with overall good diastereoselectivities and excellent enantioselectivities via chiral phosphoric acid-catalyzed onepot asymmetric formal (5+1) cycloaddition/oxidation reaction. Moreover, such indolyl quinazolinones bearing vicinal N-N/CC diaxes have good configurational stability and could be converted into new chiral ligands with applications in asymmetric catalysis. Therefore, this work not only offered a new member for the family of diaxial atropisomers, but also provided a powerful strategy for catalytic asymmetric synthesis of atropisomers bearing N-N/C-C diaxes.

关键词：

Carbon dots self-assembly enables near-infrared emission

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 2025年

作者： Shurong Ding Shasha Liu yuzhuo Yang Linlin Shi Yongqiang zhang Jingkun yu Haoqiang Song Yingge Shi Siyu Lu College of Chemistry Pingyuan Laboratory Zhengzhou University Henan Institute of Advanced Technology Zhengzhou University

In the fields of biomedicine, detection, and anti-counterfeiting, there is a widespread demand for cost-effective, easily synthesized, and environmentally friendly near-infrared(NIR) materials. Carbon dots(CDs), a cheap and non-toxic zero-dimensional carbon nanomaterial exhibiting exceptional photoluminescence(PL) properties and facile structural modification, have emerged as a promising candidate for the development of novel NIR materials. This study presents the synthesis of CDs capable of emitting a wide range of wavelengths from blue to NIR(456–836 nm) as their concentrations increase. The incorporation of oxygen and nitrogen co-doped atoms facilitates the optimization of non-coplanar angles, thereby promoting favorable π-πstacking interactions. This leads to the formation of metal-free rigid clusters through interconnecting adjacent nanoparticles in a gear-like meshing pattern through self-assembly. Consequently, intramolecular motion is constrained, vibration coupling is mitigated, non-radiative transition losses are minimized, and efficient NIR emission from CD clusters in high concentrations is ensured. Furthermore, NIR light-emitting diode(NIR LED) based on the CD clusters was successfully fabricated and employed for various applications including information encryption, anti-counterfeiting, and penetration detection in the field of NIR imaging.

关键词：

核转录因子7类似物2基因rs7903146多态性与汉族女性乳腺癌的关系研究

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

中国全科医学 2016年第33期19卷 4051-4055页

作者：刘桂红刘静普张松张怡梅周卫华张玉娜刘月芹朱铁年河北医科大学第四医院内分泌科河北省石家庄市050011 白求恩国际和平医院肿瘤科河北医科大学第三医院检验科

目的探讨核转录因子7类似物2(TCF7L2)基因rs7903146多态性与汉族女性乳腺癌的关系。方法选取2011年1月—2012年1月于河北医科大学第四医院住院治疗且符合纳入标准的女性乳腺癌患者564例作为乳腺癌组,另选取白求恩国际和平医院同期体检... 详细信息

目的探讨核转录因子7类似物2(TCF7L2)基因rs7903146多态性与汉族女性乳腺癌的关系。方法选取2011年1月—2012年1月于河北医科大学第四医院住院治疗且符合纳入标准的女性乳腺癌患者564例作为乳腺癌组,另选取白求恩国际和平医院同期体检健康的女性394例作为正常对照组。取受试者外周血提取Dna,采用聚合酶链式反应-连接酶检测反应(PCR-LDR)法对TCF7L2基因rs7903146位点进行基因分型。比较两组患者年龄、体质指数(BMI)以及TCF7L2基因rs7903146位点CC、CT基因型频率,并分析TCF7L2基因rs7903146位点CC、CT基因型频率与乳腺癌患者临床指标(诊断时年龄、绝经状态)和病理指标[雌激素受体(ER)状态、孕激素受体(PR)状态、人类表皮生长因子受体2(HER-2)状态、P53状态、Ki-67状态、淋巴结转移情况、肿瘤直径、组织学分级、肿瘤分期、分子分型]的关系。结果两组患者年龄比较,差异无统计学意义(P>0.05);乳腺癌组BMI大于对照组(P0.05),表明研究样本具有群体代表性。两组均未检测出TT基因型,两组TCF7L2基因rs7903146位点CC、CT基因型频率比较,差异无统计学意义(P>0.05)。诊断时年龄≥50岁、绝经后的乳腺癌患者CT基因型频率高于诊断时年龄0.05)。结论 TCF7L2基因rs7903146多态性与乳腺癌的发生风险无关,其不是中国汉族女性乳腺癌的患病风险因子。

关键词：乳腺肿瘤多态现象,遗传核转录因子7类似物2基因汉族

在线全文

学校读者我要写书评

暂无评论

废加氢催化剂脱油处理方法的研究

大连大学学报 2008年第3期29卷 19-22页

作者：张玉娜张秦辛长波玉占君刘斌武跃辽宁师范大学化学化工学院辽宁大连116029 大连市第四十四中学辽宁大连116013

利用表面活性剂的渗透功能,研究了一种方便快捷、成本低廉的方法来处理工业加氢催化剂废弃物,处理效果显著,废加氢催化剂洗涤效率可达72.9%,含油量由原来的17.4%降低至2.8%,实现了脱油的目的。并摸索出最佳工艺条件为:表面活性剂质量分... 详细信息

利用表面活性剂的渗透功能,研究了一种方便快捷、成本低廉的方法来处理工业加氢催化剂废弃物,处理效果显著,废加氢催化剂洗涤效率可达72.9%,含油量由原来的17.4%降低至2.8%,实现了脱油的目的。并摸索出最佳工艺条件为:表面活性剂质量分数3%、氯化钠1%、氢氧化钠3%、油/水体积比为1:2、加热温度80±2℃、超声波作用下搅拌反应2h。

关键词：废加氢催化剂表面活性剂洗涤效率