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Food Science and Human Wellness 2024年

作者： Jingbo Liu Shengrao Li Qi Yang siwen Lü Xuanting Liu Zhiyang Du Xiaomin Shang Ting zhang Jilin Provincial Key Laboratory of Nutrition and Functional Food， College of Food Science and Engineering， Jilin University

This study investigated the preventive effects of soybean meal peptides (SPs) and their purification peptides (GTYW) on acute alcoholic liver injury. We combined the gut microbiota， metabolites， liver inflammation， and oxidative stress indicators to explore the prevention mechanism of SPs and GTYW. Results showed that SPs， GTYW effectively improved the hepatic oxidative stress and inflammatory. Additionally， SPs and GTYW reversed the effects of alcohol on the gut microbiota， which were evident in the increased abundance of Alloprevotella， Parasutterella in the GTYW group and norank-f-Muribaculaceae in the SPs group. Non-targeted metabolomic analysis showed that SPs ameliorated metabolic disorders by regulating phenylalanine， tyrosine and tryptophan biosynthesis， while GTYW regulated metabolites through α-linolenic acid metabolism and phenylalanine metabolism. Furthermore， significant correlations were observed between gut microbiota， metabolites and liver indicators. These findings confirmed that SPs and GTYW can prevent acute alcoholic liver injury.

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Prevalence and genetic characteristics of Cryptosporidium,Enterocytozoon bieneusi and Giardia duodenalis in cats and dogs in Heilongjiang province,China

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Prevalence and genetic characteristics of Cryptosporidium,En...

An Earth multi-body system elasticity and plasticity dynamics model

中国畜牧兽医学会兽医寄生虫学分会第十三次学术研讨会

作者：陶威 Yanxue Jiang Qiang Wan siwen zhang Yuqi Yang Qiao Li 李巍 College of Veterinary Medicine Northeast Agricultural University

This study investigated 319 fecal specimens of cats(n=52) and dogs(n=267) from Heilongjiang province,China for the prevalence and genetic characteristics of Cryptosporidium,Enterocytozoon bieneusi,and Giardia *** and DNA sequence analysis of the small subunit rRNA gene identified *** and *** in one cat each(3.8%) and *** and *** in 6 dogs(2.2%).Polymorphisms in the ribosomal internal transcribed spacer and phylogenetic analysis characterized zoonotic *** genotypes D,EbpC,NED1,and NED2 and host-adapted ones NED3,NED4,and PtEb IX in 18 dogs(6.7%) and human-pathogenic genotypes D and IV in 3 cats(5.8%).Genotyping based on the hypermutation of G duodenalis triosephosphate isomerase gene(TPI) facilitated identification of assemblage F in a cat(1.9%)and assemblages C and E in 12 dogs(4.5%).Subtypes of G duodenalis isolates were determined by measuring the diversity of both TPI nucleotide and amino ***,***,***,*** genotypes D,EbpC,and IV,and *** assemblage C identified herein have been documented in human infections in ***,***,***,and *** genotypes D,EbpC,and IV carried by cats or dogs also existed in wastewater in *** finding suggested pet animals could be reservoirs for human cryptosporidiosis,microsporidiosis,and giardiasis and potential sources of water contamination in China.

关键词： Cryptosporidium Enterocytozoon bieneusi Giardia duodenalis Genotyping Subtyping

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Science China(Technological Sciences) 2006年第Z2期49卷 23-29页

作者： zhang Qingxian, BI siwen & GONG Huili Education Ministry Key Laboratory of Three-Dimensional Information Extraction and Application, Capital Normal University, Beijing 100037, China State Key Laboratory of Remote Sensing Science, IRSA, Chinese Academy of Sciences, Beijing 100101, China Capital Normal Univ Educ Minist Key Lab Dimens Informat Extract & App Beijing 100037 Peoples R China Chinese Acad Sci IRSA State Key Lab Remote Sensing Sci Beijing 100101 Peoples R China

Research on the elasticity and plasticity dynamics of the Earth multi-body system, including the Earth multi-body system stratum-block's equivalent inertia force system and generalized inertia force, the Earth multi-body system stratum-block's equivalent inertia force system expressed with partial velocity and partial palstance, and Earth multi-body system generalized inertia force expressed with partial velocity and partial palstance. This research provides a theoretical foundation for further investigation of Earth multi-body dynamics.

关键词： Earth multi-body system, equivalent inertia force system, generalized inertia force, elasticity and plasticity, dynamics model.

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我国氯碱工业规模宜长期保持稳定

现代化工 1999年第10期19卷 38-40页

作者：张泗文青岛化工厂 266042

1 1998年我国氯碱市场回顾1.1 氯碱装置建设失控1995年以来,我国氯碱装置建设严重失控,特别是离子膜法烧碱,各省市区不顾市场条件大上该项目,使我国氯碱工业设备利用率越来越低(见表1).

关键词：氯碱工业工业规模中国

Multi-omics analysis of attenuated variant reveals potential evaluation marker of host damaging for SARS-CoV-2 variants

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Science China(Life Sciences) 2024年第1期67卷 83-95页

作者： Guangshan Xie Lin Zhu siwen Liu Cun Li Xin Diao Yanhao zhang Xiuli Su Yuanyuan Song Guodong Cao Li Zhong Pui Wang Xiaojuan Liu Bobo Wing-Yee Mok Shusheng zhang Dong-Yan Jin Jie Zhou Honglin Chen Zongwei Cai State Key Laboratory of Environmental and Biological Analysis Hong Kong Baptist UniversityHong Kong SARChina State Key Laboratory for Emerging Infectious Diseases and Department of MicrobiologyLi Ka Shing Faculty of MedicineThe University of Hong KongHong Kong SARChina College of Chemistry Zhengzhou UniversityZhengzhou 450001China School of Biomedical Sciences The University of Hong KongHong Kong SARChina HKBU Shenzhen Institute of Research and Continuing Education Shenzhen 518000China

SARS-CoV-2 continues to threaten human society by generating novel variants via mutation and *** high number of mutations that appeared in emerging variants not only enhanced their immune-escaping ability but also made it difficult to predict the pathogenicity and virulence based on viral nucleotide *** markers for evaluating the pathogenicity of new variants are therefore *** comparing host responses to wild-type and variants with attenuated pathogenicity at proteome and metabolome levels,six key molecules on the polyamine biosynthesis pathway including putrescine,SAM,dc-SAM,ODC1,SAMS,and SAMDC were found to be differentially upregulated and associated with pathogenicity of *** validate our discovery,human airway organoids were subsequently used which recapitulates SARS-CoV-2 replication in the airway epithelial cells of COVID-19 *** ODC1 as a proof-ofconcept,differential activation of polyamine biosynthesis was found to be modulated by the renin-angiotensin system(RAS)and positively associated with ACE2 *** experiments demonstrated that ODC1 expression could be differentially activated upon a panel of SARS-CoV-2 variants of concern(VOCs)and was found to be correlated with each VOCs’pathogenic ***,the presented study revealed the discriminative ability of key molecules on polyamine biosynthesis as a predictive marker for virulence evaluation and assessment of SARS-CoV-2 variants in cell or organoid *** work,therefore,presented a practical strategy that could be potentially applied as an evaluation tool for the pathogenicity of current and emerging SARS-CoV-2 variants.

关键词： SARS-CoV-2 multi-omics attenuated variant predictive pathogenic marker polyamine biosynthesis

Egg white peptides increase the supplementation of amino acids in vivo in inflammation period and show a positive effect on the intestinal barrier in childhood

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Food Science and Human Wellness 2024年

作者： Qi Yang Jingbo Liu siwen Lyu Ting Li Xuanting Liu Zhiyang Du Xiaomin Shang Ting zhang Huifang Ge Chunyu Xi Jilin Provincial Key Laboratory of Nutrition and Functional Food， Jilin University College of Food Science and Engineering， Jilin University State Key Laboratory of Tea Plant Biology and Utilization， School of Tea and Food Sciences and Technology， Anhui Agricultural University

Bioactive peptides have various excellent biological activities and serve as functional foods to prevent chronic diseases in the human body. This article investigated the regulatory effect of egg white peptides (EPs) on the intestine barrier of young mice with colitis. The results showed that the intake of EPs could protect the intestines from inflammation damage. Besides， the expression of tight junction (TJ) proteins and mucin is upregulated. Markedly， the intake of EPs can increase the concentration of amino acids in the serum of young mice， which is crucial for nutritional supplementation during intestinal inflammation process. Proteomics analysis implied that EPs can regulate protein expression in the intestine， involving multiple inflammatory pathways including PI3K-AKT and MAPK signaling pathway. This demonstrated the health benefits of bioactive peptides and provides a theoretical basis for the development of animal derived proteins as functional foods.

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声学超材料在低频减振降噪中的应用评述

机械工程学报 2016年第13期52卷 68-78页

作者：吴九汇马富银张思文沈礼西安交通大学机械工程学院西安710049

低频机械波在传播过程中穿透力强,难以衰减,特别是次声频段的机械波易与机体器官发生共振,对身体造成危害。为了实现对低频机械波的有效控制,解决现代工业生产和生活中普遍存在的噪声污染问题,结合最近十几年发展起来的声子晶体和声学... 详细信息

低频机械波在传播过程中穿透力强,难以衰减,特别是次声频段的机械波易与机体器官发生共振,对身体造成危害。为了实现对低频机械波的有效控制,解决现代工业生产和生活中普遍存在的噪声污染问题,结合最近十几年发展起来的声子晶体和声学超材料,系统地总结和论述通过声子晶体和声学超材料解决低频振动噪声问题的新方法。归纳和总结典型的低频振动噪声来源和对其进行控制方面存在的一些困难,介绍低频振动噪声的危害。重点概括基于声子晶体禁带特性实现低频振动噪声被动控制的相关研究工作,主要介绍通过亚波长尺寸特征的杆、薄板和薄膜类结构来实现低频振动和噪声衰减的具体方法和效果。在声学超材料的理论框架下,讨论薄膜类结构在低频振动噪声衰减中的应用及其优缺点。通过结合实际工程需要和最新研究动态,对这一领域存在的问题和后续发展趋势进行总结。研究对推动声子晶体和声学超材料在工程实践中的应用具有一定的引导意义。

关键词：低频振动噪声声子晶体声学超材料薄板结构弹性薄膜

局域共振声子结构在汽车地毯低频隔声中的应用

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汽车工程 2016年第3期38卷 362-367页

作者：张思文张军章晓轩刘宏玉刘从光朱冠妮长安汽车股份有限公司汽车工程研究总院重庆401120 汽车噪声振动和安全技术国家重点实验室重庆401120

本文首次将局域共振声子带隙特性应用于汽车地毯的隔声设计中。基于局域共振思想,对地毯EVA隔声层进行微结构设计,使其产生一定的带隙特性,从而提高地毯的低频隔声量。理论计算和试验测试都表明,所设计的具有局域共振微结构的地毯隔声层... 详细信息

本文首次将局域共振声子带隙特性应用于汽车地毯的隔声设计中。基于局域共振思想,对地毯EVA隔声层进行微结构设计,使其产生一定的带隙特性,从而提高地毯的低频隔声量。理论计算和试验测试都表明,所设计的具有局域共振微结构的地毯隔声层在400Hz附近的频率范围具有局域共振声子带隙,隔声量比没有微结构的地毯隔声层提高了约5d B,说明该设计方法在低频范围突破了隔声的质量定律,利用更轻量化的材料实现了更好的低频隔声效果,为汽车低频隔声技术和轻量化设计提供了一种新的方法。

关键词：汽车地毯低频隔声局域共振声子带隙

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亚波长金属槽阵列表面电磁场增强

中国激光 2017年第11期44卷 275-282页

作者：孙晓东张斯文吴峰杨佳宁天津工业大学电子与信息工程学院天津300387 天津市光电检测技术与系统重点实验室天津300387 天津理工大学理学院天津300384 承德医学院附属医院河北承德067000

针对表面增强拉曼散射的应用,采用严格耦合波分析方法研究了亚波长金属槽阵列的表面电磁场增强效应。模拟阵列周期和槽深对阵列槽口处电磁场增强的影响,明确了结构内部共振效应对电磁场增强的贡献,分析了亚波长金属槽阵列拉曼散射的平... 详细信息

针对表面增强拉曼散射的应用,采用严格耦合波分析方法研究了亚波长金属槽阵列的表面电磁场增强效应。模拟阵列周期和槽深对阵列槽口处电磁场增强的影响,明确了结构内部共振效应对电磁场增强的贡献,分析了亚波长金属槽阵列拉曼散射的平均增强效果及阵列外空间中电磁场增强的有效作用范围。研究表明,在槽内共振效应的影响下,亚波长金属槽阵列在一个周期内的拉曼散射增强因子可达106数量级,并在垂直距离阵列表面1/5波长的范围内可得到明显的电磁场增强,超出该范围增强因子将迅速衰减到1的数量级。数值结果表明阵列表面电磁场增强几乎不受贵金属类型的影响。

关键词：表面光学表面增强拉曼散射电磁场增强亚波长金属槽阵列严格耦合波分析

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串行流化床内气体串混特性

化工学报 2012年第7期63卷 2017-2024页

作者：张思文吴家桦顾海明沈来宏肖军东南大学热能工程研究所江苏南京210096 中国东方电气集团有限公司中央研究院新能源与发电技术研究所四川成都611731

串行流化床反应器间的气体串混是影响化学链燃烧过程的关键因素之一,采用串行流化床冷态试验装置,通过改变各反应器入口流化数,考察反应器间的串混量及串混率。反应器之间的气体串混路径可能有空气反应器和燃料反应器之间的气体串混、... 详细信息

串行流化床反应器间的气体串混是影响化学链燃烧过程的关键因素之一,采用串行流化床冷态试验装置,通过改变各反应器入口流化数,考察反应器间的串混量及串混率。反应器之间的气体串混路径可能有空气反应器和燃料反应器之间的气体串混、燃料反应器内气体向旋风分离器串混、隔离器气体在空气反应器和燃料反应器内的分布。结果表明,在空气反应器和燃料反应器之间加设隔离器能有效阻止两个反应器之间发生气体串混;燃料反应器内少许气体通过反应器内料腿向上串混到旋风分离器排气中,串混率约为2%,这使得该串行流化床化学链燃烧的理论碳捕集效率可以达到98%;燃料反应器流化风速对隔离器内气体在两个反应器的分布影响较小,采用水蒸气流化可避免隔离器气体向空气反应器和燃料反应器内串混所带来的影响。

关键词：化学链燃烧串行流化床气体串混 CO2分离