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Orthogonal Time Frequency Space Modulation in 6G Era

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China Communications 2023年第1期20卷 I0002-I0005页

作者： Weijie Yuan Zhiqing Wei Jiamo Jiang shun zhang Jinhong Yuan Pingzhi Fan the Department of Electrical and Electronic Engineering Southern University of Science and Technology IEEE Com Soc Special Interest Group on Orthogonal Time Frequency Space (OTFS-SIG) the Beijing University of Posts and Telecommunications (BUPT) Mobile Communications Innovation Center (MCIC) China Academy of Information and Communications Technology (CAICT) the State Key Laboratory of Integrated Services Networks Xidian University the School of Electrical Engineering and Telecommunications University of New South Wales Telecommunication Group University of New South Wales the Institute of Mobile Communications Southwest Jiaotong University

Over the past decades, wireless technologies with reliable data transmissions and precise sensing ability in hostile environments are much less understood and significantly under-developed. The DD domain waveform, e.g., orthogonal time frequency space(OTFS), has been recognized globally for its great potential to achieve high-reliable communications and robust sensing performance under various channel conditions in 6G era.

关键词： wireless globally precise

Neurite Orientation Dispersion and Density Imaging of Rat Brain Microstructural Changes due to Middle Cerebral Artery Occlusion at a 3T MRI

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Current Medical Science 2021年第1期41卷 167-172页

作者： Zhen-xiong WANG Wen-zhen ZHU shun zhang Mehran Shaghaghi Ke-jia CAi Department of Radiology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China Department of Radiology Department of Bioengineeringand the Center for MR ResearchUniversity of Illinois at ChicagoChicago60612USA

The purpose of this work was to demonstrate the feasibility of neurite orientation dispersion and density imaging(NODDI)in characterizing the brain tissue microstructural changes of middle cerebral artery occlusion(MCAO)in rats at 3T MRI,and to validate NODDI metrics with histology.A multi-shell diffusion MRI protocol was performed on 11 MCAO rats and 10 control rats at different post-operation time points of 0.5,2,6,12,24 and 72 *** orientation dispersion index(ODI)and intracellular volume fraction(V_(ic))metrics were compared between MCAO group and control *** evolution of NODDI metrics was characterized and validated by *** was consistent with significantly increased ODI and V_(ic)in comparison to control tissues at all time points(P<0.001).Lesion ODI increased gradually from 0.5 to 72 h,while its V_(ic)showed a more complicated and fluctuated *** and V_(ic)were significantly different between hyperacute and acute stroke periods(P<0.001).The NODDI metrics were found to be consistent with the histological *** conclusion,NODDI can reflect microstructural changes of brain tissues in MCAO rats at 3T MRI and the metrics are consistent with *** study helps to prepare NODDI for the diagnosis and management of ischemic stroke in translational research and clinical practice.

关键词： diffusion magnetic resonance imaging neurite orientation dispersion and density imaging middle cerebral artery occlusion model stroke rats

Efficacy and Safety of Bufei Jiedu Granules in Treating Multidrug-Resistant Pulmonary Tuberculosis:A Multi-center,Double-Blinded and Randomized Controlled Trial

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Chinese Journal of Integrative Medicine 2024年第7期30卷 579-587页

作者： zhang Shao-yan QIU Lei zhang shun-xian XIAO He-ping CHU Nai-hui zhang Xia zhang Hui-qiang ZHENG Pei-yong zhang Hui-yong LU Zhen-hui Institute of Respiratory Diseases Longhua HospitalShanghai University of Traditional Chinese MedicineShanghai200032China Clinical Research Center Shanghai University of Traditional Chinese MedicineShanghai200032China Department of Tuberculosis Shanghai Pulmonary HospitalTongji UniversityShanghai200433China Department of Tuberculosis Beijing Chest HospitalCapital Medical UniversityBeijing101100China Department of Tuberculosis the Second Hospital of NanjingNanjing210003China Department of Tuberculosis the First Hospital Affiliated to Xinxiang Medical CollegeXinxiangHenan Province453100China

Objective: To assess the efficacy and safety of Bufei Jiedu(BFJD) Granules as adjuvant therapy for patients with multidrug-resistant pulmonary tuberculosis(MDR-PTB). Methods: A large-scale, multi-center, double-blinded, and randomized controlled trial was conducted in 18 sentinel hospitals in China from December 2012 to December 2016. A total of 312 MDR-PTB patients were randomly assigned to BFJD Granules or placebo groups(1:1) using a stratified randomization method, which both received the long-course chemotherapy regimen for 18 months(6 Am-Lfx-P-Z-Pto, 12 Lfx-P-Z-Pto). Meanwhile, patients in both groups also received BFJD Granules or placebo twice a day for a total of 18 months, respectively. The primary outcome was cure rate. The secondary outcomes included time to sputum-culture conversion, changes in lung cavities and quality of life(QoL) of patients. Adverse reactions were monitored during and after the trial. Results: A total of 216 cases completed the trial, 111 in the BFJD Granules group and 105 in the placebo group. BFJD Granules, as adjuvant treatment, increased the cure rate by 13.6% at the end of treatment, compared with the placebo(58.4% vs. 44.8%, P=0.02), and accelerated the median time to sputum-culture conversion(5 months vs. 11 months). The cavity closure rate of the BFJD Granules group(50.6%, 43/85) was higher than that of the placebo group(32.1%, 26/81;P=0.02) in patients who completed the treatment. At the end of the intensive treatment, according to the 36-item Short Form, the BFJD Granules significantly improved physical functioning, general health, and vitality of patients relative to the placebo group(all P<0.01). Overall, the death rates in the two groups were not significantly different;5.1%(8/156) in the BFJD Granules group and 2.6%(4/156) in the placebo group. Conclusions: Supplementing BFJD Granules with the long-course chemotherapy regimen significantly increased the cure rate and cavity closure rate, and rapidly improved QoL of pati

关键词： alternative medicine Chinese herbal formula Bufei Jiedu Granules multidrug-resistant tuberculosis long-course chemotherapy regimen randomized controlled trial

Roles of Carbohydrate Supply and Ethylene,Polyamines in Maize Kernel Set

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Journal of Integrative Plant Biology 2011年第5期53卷 388-398页

作者： Han-Yu Feng Zhi-Min Wang Fan-Na Kong Min-Jie zhang shun-Li Zhou College of Agronomy & Biotechnology China Agricultural University Beijing 100193 China

Glucose appears to have an antagonistic relationship with ethylene and ethylene and polyamines appear to play antagonistic roles in the abortion of seeds and fruits. Moreover, ethylene, spermidine, and spermine share a common biosynthetic precursor. The synchronous changes of them and the relationships with kernel set are currently unclear. Here, we stimulated maize （Zea mays L.） apical kernel set and studied their changes at 4, 8, 12, and 16 d after pollination （DAP）. The status of the apical kernels changed from abortion to set, showing a pattern similar to that of the middle kernels, with slow decrease in glucose and rapid decline in ethylene production, and a sharp increase in spermidine and spermine after four DAP. Synchronous changes in ethylene and spermidine were also observed. However, the ethylene production decreased slowly in the aborted apical kernels, the glucose and polyamines concentrations were lower. Ethephon application did not block the change from abortion to set for the setting apical kernels. These data indicate that the developmental change may be accompanied by an inhibition of adequate glucose to ethylene synthesis and subsequent promotion of spermidine and spermine synthesis, and adequate carbohydrate supply may play a key role in the developmental process.

关键词： CARBOHYDRATES ETHYLENE POLYAMINES CORN POLLINATION SPERMIDINE ETHEPHON GLUCOSE

Coherent interface strengthening of ultrahigh pressure heat-treated Mg-Li-Y alloys

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Journal of Materials Science & Technology 2020年第16期47卷 79-83页

作者： shun zhang Yong Sun Ruizhi Wu Xiang Wang Xiao-Bo Chen Carlos Fernandez Qiuming Peng State Key Laboratory of Metastable Materials Science and Technology Yanshan UniversityQinhuangdao066004China Key Laboratory of Superlight Materials&Surface Technology Ministry of EducationHarbin Engineering UniversityHarbin150001China School of Engineering RM IT UniversityCarlton3053VICAustralia School of Pharmacy and Life Sciences Robert Gordon UniversityAberdeenAB107GJUK

Achieving good strength-ductility of Mg alloys has always been a crucial issue for the widespread applications of Mg-based structural ***,an unexpected double-stage strengthening phenomenon was discovered in Mg-8Li-1Y(wt.%)alloys through high pressure(6 GPa)heat treatments over a range of 700-1300℃.Attractively,the yield strength values are improved remarkably without losing their *** low temperature strengthening mechanism is mainly driven by the formation of large-volume nanoscale contraction *** contrast,the high-temperature strengthening reason is ascribed to the presence of densely nano-sized stacking *** coherent interfaces contribute effectively to high mechanical strength without any tradeoff in ductility.

关键词： Mg alloys Nano-twins Stacking faults Strengthening

Low-dose dopamine reduces inflammatory factors of acute pancreatitis in rats

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Hepatobiliary & Pancreatic Diseases International 2007年第6期6卷 646-649页

作者： zhang, shun Peng, Xin-Gang Liu, Chang-Chang Liu, Hong Lu, Yun Qingdao Univ Affiliated Hosp Coll Med Dept Hepatobiliary Surg Qingdao 266003 Peoples R China Qingdao Univ Affiliated Hosp Coll Med Dept Emergency Gen Med Qingdao 266003 Peoples R China

BACKGROUND: Acute pancreatitis, especially acute necrotizing pancreatitis (ANP), is a serious disease with a high morbidity because of multiorgan dysfunction. Recent studies have indicated that during the pathogenesis of ANP, changes of the microcirculation play an important role in the worsening of the disease. This study based on a. model of acute pancreatitis in Wistar rats was to determine the effect of treatment with low-dose dopamine on acute pancreatitis by the dynamic measurement of serum levels of inflammatory factors IL-6 and TNF-alpha. METHODS: Fifty Wistar rats were randomly divided into two groups, and a model of ANP was set up by injecting sodium taurocholate into the pancreatic duct. Rats in the dopamine group (treatment group) were given dopamine by vein and those in the acute pancreatitis group (control group) were given normal saline. To assess the effect of low-dose doparnine (5 mu g . kg(-1) . min(-1)) on induced acute pancreatitis, the antibody sandwich ELISA method was used to measure the serum levels of IL-6 and TNF-alpha at different times before and after the induction of ANP. RESULTS: The serum levels of IL-6 and TNF-alpha in the treatment and control groups before and after ANP induction were significantly different. There was a markedly significant difference in the comparison of the two groups after ANP induction (P0.05). Postoperative pancreatic histopathologic changes in the treatment group were more marked than those in the control group. CONCLUSIONS: Low-dose dopamine is effective in treating ANP by alleviating inflammatory reactions. This effect may be related to the fact that low-dose doparnine not only can increase the blood flow of the pancreatic microcirculation but also reduce its permeability.

关键词： acute pancreatitis dopamine inflammatory factor

Current clinical trials on gastric cancer surgery in China

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World Journal of Gastrointestinal Oncology 2024年第11期16卷 4369-4382页

作者： shun zhang Ren-Hao Hu Xi-Mao Cui Chun Song Xiao-Hua Jiang Department of Gastrointestinal Surgery Shanghai East HospitalSchool of MedicineTongji UniversityShanghai 200120China

Gastric cancer(GC)is the leading diagnosed malignancy worldwide,especially in *** surgery is the cornerstone of GC *** reviewed previous clinical trials and aimed to provide an update on the factors related to the surgical treatment of *** number of registered clinical trials in the field of GC surgery is rapidly *** the development and popularization of endoscopic,laparoscopic,and robotic techniques,GC surgery has gradually entered a new era of precise minimally invasive *** quality of life has become a major issue in addition to surgical oncological *** great progress has been made in clinical research on GC in China,there are still *** studies enrolled large numbers of patients,but the research data were not of high *** characteristics of GC in China include a high incidence,large population,and large proportion of patients with advanced GC,which provides sufficient reason for studying this *** is still a need for well-designed,large,randomized clinical trials to improve our knowledge of the surgical treatment of GC.

关键词： Gastric cancer Clinical trial Surgery China Minimally invasive surgery Quality of life

Joint Characteristics and Corrosion Properties of Bypass-Current Double-Sided Arc-Welded Aluminum 6061 Alloy with Al–Si Filler Metal

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Acta Metallurgica Sinica(English Letters) 2016年第4期29卷 360-366页

作者： Yu-Gang Miao Ben-shun zhang Bin-Tao Wu Xiao-Xiao Wang Guang-Yu Chen Duan-Feng Han National Key Laboratory of Science and Technology on Underwater Vehicle Harbin Engineering University

Sheets of aluminum 6061 alloy were welded using bypass-current double-sided arc welding with Al-Si filler wire to investigate the effect of Al-Si intermetallic compounds on the microstructure, microhardness and corrosion behavior of weld joint. Experimental results indicated that the Al4.5FeSi phase in the topside of the weld joint was finer than that in the backside and newly formed phase of Al0.5Fe3Si0.5 was observed in the backside. The formation of reinforcing phases of Al-Fe-Si in the weld improved the microhardness of the weld by about 18%. The corrosion resistance of the weld zone was greater than that of the base metal, while the corrosion current displayed opposite, and the corrosion resistance of the weld region was better than that of the base metal.

关键词： Bypass-current double-sided arc welding Aluminum 6061 alloy Joint characteristics Interface analysis Microhardness Corrosion behavior

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东营凹陷页岩储层成岩作用及增孔和减孔机制

中国矿业大学学报 2018年第3期47卷 562-578页

作者：张顺中石化胜利油田勘探开发研究院山东东营257022 中国石化胜利油田博士后流动工作站山东东营257000

以济阳坳陷东营凹陷古近系页岩储层为研究对象,利用岩石薄片观察、X射线衍射全岩矿物含量分析、电子探针分析、碳氧同位素测试分析、氩离子抛光和场发射环境扫描电镜分析、低温氮气吸附实验等技术方法,研究孔隙类型及组合样式,分析成岩... 详细信息

以济阳坳陷东营凹陷古近系页岩储层为研究对象,利用岩石薄片观察、X射线衍射全岩矿物含量分析、电子探针分析、碳氧同位素测试分析、氩离子抛光和场发射环境扫描电镜分析、低温氮气吸附实验等技术方法,研究孔隙类型及组合样式,分析成岩流体环境及架构矿物演化特征,划分成岩阶段,明确孔隙的发育演化主要受控于黏土矿物转化和碳酸盐矿物的含量、成岩作用强度及其溶蚀程度,增孔和减孔机制的界限并不严格.研究结果表明:东营凹陷页岩储层发育基质孔隙组合、基质孔隙-有机孔隙组合、裂缝沟通基质孔隙组合等多种类型孔隙组合(包含微裂缝),孔隙面貌复杂;受地层水介质及原始沉积环境影响,局部层段酸性碱性流体交替控制细粒物质的成岩演化,总体呈现由碱性—弱碱性—酸性—弱碱性的成岩环境变化特征;有机质成熟度较低(Ro<1.0%),成岩阶段处于中成岩阶段,早成岩B期—中成岩B期是孔隙演化的关键时期;压实作用下黏土矿物的脱水转化与催化生烃、溶蚀与沉淀作用共存、方解石近源重结晶与有机质生烃排酸的共同作用造成了孔隙的动态演化;黏土矿物转化、有机质生烃、方解石等脆性矿物的成岩作用对储层孔隙体系的演化起到了重要的作用.

关键词：页岩储层孔隙组合成岩演化增孔和减孔机制东营凹陷古近系