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Design and test of a double compression seeder for pre-sowing and seed furrow of wheat in wide-seedling belts

International Journal of Agricultural and Biological Engineering 2024年第4期17卷 136-145页

作者： Xun He run zhang Jingfeng zhang Yinghao Zhu Wanzhang Wang Hongmei zhang College of Mechanical and Electrical Engineering Henan Agricultural UniversityZhengzhou 450002China

To solve the problem of poor sowing quality due to loose soil in wheat seedbed after land preparation in the Huang-Huaihai region of China,a double compression seeder for pre-sowing and seed furrow of wheat in wide-seedling belts was *** machine sowing operation was divided into two processes:pre-sowing compression and seed ditch compression,pre-sowing compression was carried out homogenization of the pre-sowing seed bed that the tractor wheel has crushed,and the seed ditch compression compresses the seeds and soil in the seed ditch,so that the seeds were embedded in the seed ditch *** analyzing the kinematics of the pre-planting compression device and the spiral blade in the process of soil levelling and compression,the structure of the equal-difference variable-diameter equal-pitch spiral conveying winch was designed,and the key parameters of the drum spiral blade were determined,and then the height of the spiral blades,the rutting distance and the speed of the compression roller were taken as the test factors,and the soil flatness was used as the index to carry out the discrete element simulation *** simulation results show that when the spiral blade was 4.85 cm,the rut distance was 37.4 cm,and the rotation speed was 327.16 r/min,the optimal land flatness was ***,field experiments were carried out on the seeder,and the results showed that:the soil bulk density after operation was 22.7%greater than that before sowing(p<0.01),and the soil flatness was 1.9 cm,which was consistent with the simulated *** use of pre-sowing compression and seed furrow compression methods improved the soil environment of the seed bed,increased the uniformity of the seeding depth,and promoted the root growth of *** study provides equipment support and technical reference for agricultural production in wheat-corn rotation areas in the Huang-Huaihai region of China.

关键词： wheat seeding quality pre-sowing compression seed furrow compression field experiment

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Associations Between Changes in Physical Activity and Risk of All-Cause Mortality in Adults With/Without Hypertension—China,2010-2022

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China CDC weekly 2024年第40期6卷 1038-1043页

作者： Xiaoyong He Tingfang Ai Fan Mao run zhang Xiaoqing You Jianhong Li National Center for Chronic and Noncommunicable Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina

What is already known about this topic?Previous studies indicate that an increase in physical activity can diminish the risk of ***,the relationship between longitudinal changes in physical activity and health improvement among Chinese adults with or without hypertension has not been *** is added by this report?This study found that increasing or maintaining moderate to high physical activity levels reduced the risk of all-cause mortality,irrespective of the baseline physical activity *** addition,the beneficial effects were particularly pronounced in people with *** are the implications for public health practice?It may be beneficial to encourage adults in China,especially those with hypertension,to actively increase physical activity and deter the issue of physical inactivity that accompanies aging.

关键词： mortality hypertension companies

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Enarbolar juntos la bandera de la era

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今日中国（西文版） 2024年第2期 36-37页

作者： zhang run 不详

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Anti-inflammatory and DNA Repair Effects of Astragaloside IV on PC12 Cells Damaged by Lipopolysaccharide

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Current Medical Science 2024年第4期44卷 854-863页

作者： Hai-long LI Li-hua SHAO Xi CHEN Meng WANG Qi-jie QIN Ya-li YANG Guang-run zhang Yang HAI Yi-hong TIAN Department of Geriatrics The Affiliated Hospital of Gansu University of Chinese MedicineLanzhou730000China Key Laboratory for Mining Innovation and Transformation of Traditional Chinese Medicine in Gansu Province and the New Product Creation Engineering Laboratory of Traditional Chinese Medicine in Gansu ProvinceLanzhou730000China Department of Neurology the First People’s Hospital of LanzhouLanzhouGansu730000China School of Public Health Gansu University of Chinese MedicineLanzhou730000China People’s Hospital of Gansu Province Lanzhou730000China Scientific Research and Experimental Center Gansu University of Chinese MedicineLanzhou730000China

Objective This study aimed to establish a neural cell injury model in vitro by stimulating PC12 cells with lipopolysaccharide(LPS)and to examine the effects of astragaloside IV on key targets using high-throughput sequence technology and bioinformatics *** PC12 cells in the logarithmic growth phase were treated with LPS at final concentrations of 0.25,0.5,0.75,1,and 1.25 mg/mL for 24 *** morphology was evaluated,and cell survival rates were calculated.A neurocyte inflammatory model was established with LPS treatment,which reached a 50%cell survival ***12 cells were treated with 0.01,0.1,1,10,or 100µmol/L astragaloside IV for 24 *** concentration of astragaloside IV that did not affect the cell survival rate was selected as the treatment group for subsequent *** activity was detected by colorimetry;the expression levels of ERCC2,XRCC4,XRCC2,TNF-α,IL-1β,TLR4,NOS and COX-2 mRNA and protein were detected by RT-qPCR and Western *** differentially expressed genes(DEGs)between the groups were screened using a second-generation sequence(fold change>2,P0.05).However,after treatment with 0.5,0.75,1,or 1.25 mg/mL LPS for 24 h,the viability steadily decreased(P<0.01).The mRNA and protein expression levels of ERCC2,XRCC4,XRCC2,TNF-α,IL-1β,TLR4,NOS,and COX-2 were significantly increased after PC12 cells were treated with 1 mg/mL LPS for 24 h(P<0.01);however,these changes were reversed when PC12 cells were pretreated with 0.01,0.1,or 1µmol/L astragaloside IV in PC12 cells and then treated with 1 mg/mL LPS for 24 h(P<0.05).Second-generation sequencing revealed that 1026 genes were upregulated,while 1287 genes were downregulat

关键词： PC12 cells astragaloside IV inflammation DNA damage

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Efficacy of Chinese Medicine Treatment Based on Syndrome Differentiation for Primary Insomnia:A Randomized Placebo Controlled Triple-Blinded Trial

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Chinese Journal of Integrative Medicine 2024年第10期30卷 867-876页

作者： XIONG Zhi-yi LU Ying HE Li-yun zhang run-shun ZHOU Xue-zhong LI Peng LIU Yan-jiao ZHU Jian-gui YAN Shi-yan LIU Bao-yan International Acupuncture and Moxibustion Innovation Institute School of Acupuncture-Moxibustion and Tuina Beijing University of Chinese Medicine Department of Biomedical Data Science Stanford University School of Medicine Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical Sciences Guang'anmen Hospital China Academy of Chinese Medical Sciences Beijing Jiaotong University School of Computer and Information Technology Beijing Xicheng District Community Healthcare Center China Academy of Chinese Medical Sciences

Objective: To assess efficacy of Chinese medicine(CM) on insomnia considering characteristics of treatment based on syndrome differentiation. Methods: A total of 116 participants aged 18 to 65 years with moderate and severe primary insomnia were randomized to the placebo(n=20) or the CM group(n=96) for a 4-week treatment and a 4-week follow-up. Three CM clinicians independently prescribed treatments for each patient based on syndromes differentiation. The primary outcome was change in total sleep time(TST) from baseline. Secondary endpoints included sleep onset latency(SOL), wake time after sleep onset(WASO), sleep efficiency, Pittsburgh Sleep Quality Index(PSQI) and CM symptoms. Results: The CM group had an average 0.6 h more(95% confidence interval(CI): 0.3–0.9, P<0.001) TST and 34.1%(10.3%–58.0%, P=0.005) more patients beyond 0.5 h TST increment than that of the placebo group. PSQI was changed –3.3(–3.8 to –2.7) in the CM group, a –2.0(–3.2 to –0.8, P<0.001) difference from the placebo group. The CM symptom score in the CM group decreased –2.0(–3.3 to –0.7, P=0.003) more than the placebo group. SOL and WASO changes were not significantly different between groups. The analysis of prescriptions by these clinicians revealed blood deficiency and Liver stagnation as the most common syndromes. Prescriptions for these clinicians displayed relative stability, while the herbs varied. All adverse events were mild and were not related to study treatment. Conclusions: CM treatment based on syndrome differentiation can increase TST and improve sleep quality of primary insomnia. It is effective and safe for primary insomnia. In future studies, the long-term efficacy validation and the exploratory of eutherapeutic clinicians' fixed herb formulas should be addressed.(Registration No. NCT01613183)

关键词： Chinese medicine primary insomnia randomized controlled trial syndrome differentiation

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善治视野下审判权运行规律的法理阐释

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学海 2024年第3期 85-94,215页

作者：章润南京大学法学院南京210093

党的二十大报告提出了“以良法促进发展、保障善治”的要求。善治是社会治理的一种理想形态,善治的实现离不开审判权功能的发挥。作为一种创新性的治理理念,善治为衡量审判权运行能否维护和促进社会公平正义提供了标准。在善治视野下,... 详细信息

党的二十大报告提出了“以良法促进发展、保障善治”的要求。善治是社会治理的一种理想形态,善治的实现离不开审判权功能的发挥。作为一种创新性的治理理念,善治为衡量审判权运行能否维护和促进社会公平正义提供了标准。在善治视野下,审判权运行规律具有有效满足司法需求、妥善平衡利益关系、切实保障公民权利以及实现审判活动与社会公众良性互动等特定意蕴,由审判权独立行使、恪守司法公正、纠纷有效解决、审判公开透明、公众有序参与等要素构成,具有回应性、协同性、柔和性、开放性和引导性等特点。

关键词：善治审判权司法规律司法制度司法改革

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Analgesic nanomedicines for the treatment of chronic pain

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BMEMat(BioMedical Engineering Materials) 2024年第1期2卷 76-87页

作者： Hao Liu Hongjun Zhuang Ya Wang Yuen Yee Cheng Feixiang Chen Jian Chen Xinglei Song run zhang Yanyan Liu Wenbo Bu State Key Laboratory of Molecular Engineering of Polymers Department of Materials ScienceFudan UniversityShanghaiChina Department of Rehabilitation Zhongshan HospitalFudan UniversityShanghaiChina Central Laboratory The First Affiliated Hospital of Xiamen UniversityXiamenChina Institute for Biomedical Materials&Devices(IBMD) Faculty of ScienceThe University of Technology SydneySydneyNew South WalesAustralia Department of Anatomy and Physiology Shanghai Jiao Tong University School of MedicineShanghaiChina Australian Institute for Bioengineering and Nanotechnology The University of QueenslandBrisbaneQueenslandAustralia

Chronic pain is a major cause of suffering that often accompanies diseases and therapies,affecting approximately 20%of individuals at some point in their ***,current treatment modalities,such as anesthetic and antipyretic analgesics,have limitations in terms of efficacy and side *** technology offers a promising avenue to overcome these challenges and introduce new therapeutic *** article reviews the recent research on nanomedicine analgesics,integrating analyses of neuroplasticity changes in neurons and pathways related to the transition from acute to chronic ***,it explores potential future strategies using nanomaterials,aiming to provide a roadmap for new analgesic development and improved clinical pain *** leveraging nanotechnology,these approaches hold the potential to revolutionize pain treatment by delivering targeted and effective relief while minimizing side effects.

关键词： analgesics chronic pain local anesthetics nanomedicine neuroplasticity

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Investigation of edge states variation in valley photonic crystals by modulating the refractive index of domain walls

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Optoelectronics Letters 2024年

作者： zhang run ZHONG Xingli LIN Zhongxi QIU Weibin SU Hui Key Laboratory of Optoelectronic Materials Chemistry and Physics， Collaborative Innovation Center for Optoelectronic Semiconductors and Efficient Devices， Fujian Institute of Research on the Structure of Matter， Chinese Academy of Science University of Chinese Academy of Sciences， Chinese Academy of Sciences College of Information Science and Engineering， Huaqiao University Fujian Science & Technology Innovation Laboratory for Optoelectronic Information of China

Realizing the valley Hall effect by breaking the spatial inversion symmetry of photonic systems has become a cutting-edge field of micro-nano-optics， since the valley degree of freedom was introduced into photonic system. Various novel devices based on the domain walls of the valley photonic crystals have also been demonstrated. In this article， we investigate the variation of edge states by the modulation of refractive index within the domain walls， and the geometric difference between the dielectric columns of the sublattices. Straight photonic crystal waveguides with three types of domain walls (bearded， zigzag， armchair) are constructed. Simulation results show that the creation of a double-edge state in the band diagram results in two windows of stable transmission in tunable bands. Our findings might have significant implications in the field of novel optical devices.

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A shape-reconfigurable,light and magnetic dual-responsive shape-memory micropillar array chip for droplet manipulation

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Chinese Chemical Letters 2024年第1期35卷 456-460页

作者： Wen-Qi Ye Wen-Xin Fu Xiao-Peng Liu Chun-Guang Yang zhang-run Xu Research Center for Analytical Sciences Northeastern UniversityShenyang 110819China

Droplet manipulation on an open surface has great potential in chemical analysis and biomedicine ***,most of the reported platforms designed for the manipulation of water droplets cannot thoroughly solve the problem of droplet ***,we report a shape-reconfigurable micropillar array chip for the manipulation of water droplets,oil droplets and water-in-oil ***-in-oil droplets provide an enclosed space for water droplets,preventing the evaporation in an open *** coated on the surface of the chip effectively reduces the droplet movement *** micropillar array chip has light and magnetic dual-response due to the Fe3O4 nanoparticles and the reduced iron powder mixed in the shape-memory *** micropillars irradiated by a near-infrared laser bend under the magnetic force,while the unirradiated micropillars still keep their original *** the absence of a magnetic field,when the micropillars in a temporary shape are irradiated by the near-infrared laser to the transition temperature,the micropillars return to their initial *** this process,the surface morphology gradient caused by the deformation of the micropillars and the surface tension gradient caused by the temperature change jointly produce the driving force of droplet movement.

关键词： Microfluidics Droplet manipulation Micropillar array Shape memory polymer Magnetic response Light response

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Preoperative systemic inflammatory response index as a prognostic marker for distal cholangiocarcinoma after pancreatoduodenectomy

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World Journal of Gastrointestinal Surgery 2024年第9期16卷 2910-2924页

作者： Wen-Hui zhang Yu Zhao Cheng-run zhang Jin-Can Huang Shao-Cheng Lyu Ren Lang Department of Hepatobiliary Surgery Beijing Chao-Yang Hospital Affiliated to Capital Medical UniversityBeijing 100020China Department of Urology Surgery Beijing Chao-Yang Hospital Affiliated to Capital Medical UniversityBeijing 100020China

BACKGROUND The relationship between preoperative inflammation status and tumorigenesis as well as tumor progression is widely *** To assess the prognostic significance of preoperative inflammatory biomarkers in patients with distal cholangiocarcinoma(dCCA)who underwent pancreat-oduodenectomy(PD).METHODS This single-center study included 216 patients with dCCA after PD between January 1,2011,and December 31,*** individuals were categorized into two sets based on their systemic inflammatory response index(SIRI)levels:A low SIRI group(SIRI<1.5,n=123)and a high SIRI group(SIRI≥1.5,n=93).Inflam-matory biomarkers were evaluated for predictive accuracy using receiver operating characteristic *** univariate and multivariate Cox proportional hazards analyses were performed to estimate SIRI for overall survival(OS)and recurrence-free survival(RFS).RESULTS The study included a total of 216 patients,with 58.3%being male and a mean age of 65.6±9.6 years.123 patients were in the low SIRI group and 93 were in the high SIRI group after PD for *** had an area under the curve value of 0.674 for diagnosing dCCA,showing better performance than other inflammatory *** analysis indicated that having a SIRI greater than 1.5 independently increased the risk of dCCA following PD,leading to lower OS[hazard ratios(HR)=1.868,P=0.006]and RFS(HR=0.949,P<0.001).Additionally,survival analysis indicated a significantly better prognosis for patients in the low SIRI group(P<0.001).CONCLUSION It is determined that a high SIRI before surgery is a significant risk factor for dCCA after PD.

关键词： Distal cholangiocarcinoma Pancreatoduodenectomy Biomarker Systemic inflammatory response index Prognosis

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