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南岭科学钻中与两种岩浆岩有关的矿床成矿系列--年代学、地球化学、Hf同位素证据

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地球学报 2015年第6期36卷 742-754页

作者：郭娜欣陈毓川赵正吕晓强刘珍陈郑辉曾载淋李江东张凤荣中国地质科学院北京100037 中国地质科学院矿产资源研究所国土资源部成矿作用与资源评价重点实验室北京100037 北京矿产地质研究院北京100012 江西省地质矿产勘查开发局赣南地质调查大队江西赣州341000

南岭科学钻（SP-NLSD-1）位于南岭成矿带与武夷山成矿带的交汇部位——赣南银坑矿田。该钻孔总进尺2967.83 m,钻遇了流纹岩、花岗斑岩、花岗闪长斑岩、辉长闪长玢岩等四种岩浆岩。流纹岩为银坑矿田新揭露的岩石类型,LA-ICP-MS锆石U-Pb... 详细信息

南岭科学钻（SP-NLSD-1）位于南岭成矿带与武夷山成矿带的交汇部位——赣南银坑矿田。该钻孔总进尺2967.83 m,钻遇了流纹岩、花岗斑岩、花岗闪长斑岩、辉长闪长玢岩等四种岩浆岩。流纹岩为银坑矿田新揭露的岩石类型,LA-ICP-MS锆石U-Pb定年表明其形成于（381.0±3.1）ma,补充完善了本区海西期岩浆活动的记录;花岗斑岩、花岗闪长斑岩、辉长闪长玢岩的成岩时代为101.3-161.0 ma,为燕山期岩浆活动的产物。流纹岩与花岗斑岩具有相似的地球化学特征,球粒陨石标准化稀土元素配分曲线为两翼近平坦的海鸥型,有明显的Eu负异常,显著富集大离子亲石元素,轻微富集高场强元素,锆石εHf（t）值分别为–10.8-–7.1、–23.4-–8.7;花岗闪长斑岩与辉长闪长玢岩的地球化学特征相似,球粒陨石标准化稀土元素配分曲线为右倾型,Eu负异常不明显,显著富集大离子亲石元素,轻微富集高场强元素,花岗闪长斑岩的锆石εHf（t）值为–17.9-–1.9。岩相学、年代学和地球化学研究结果表明,流纹岩、花岗斑岩、花岗闪长斑岩、辉长闪长玢岩应该均为古元古代地壳物质重熔形成的壳源岩浆岩,花岗闪长斑岩和辉长闪长玢岩在形成过程中可能继承了幔源物质。流纹岩与银坑矿田内已知的成矿作用无直接关系,花岗斑岩与钨铋铀矿化有关,花岗闪长斑岩与铜铅锌金银矿化有关。银坑矿田处于特殊的构造部位,即南岭成矿带与武夷山成矿带交汇部位,深达地幔的线型断裂和切入地壳的网格状断裂同时在此处发育,不同的构造环境导致在燕山期形成花岗闪长斑岩和花岗斑岩,分别对应铜铅锌金银矿化和钨多金属矿化,形成两个相对独立的成矿系列。

关键词：南岭科学钻岩浆岩成矿系列银坑矿田

Feasibility and physics potential of detecting ^(8)B solar neutrinos at JUNO

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Chinese Physics C 2021年第2期45卷 93-110页

作者： Angel Abusleme Thomas Adam Shakeel Ahmad Sebastiano Aiello Muhammad Akram Nawab Ali Fengpeng An Guangpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde marcondes de André Didier Auguste Andrej Babic Wander Baldini Andrea Barresi Eric Baussan marco Bellato Antonio Bergnoli Enrico Bernieri David Biare Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano max Buesken mario Buscemi Jose Busto Ilya Butorov Anatael Cabrera Hao Cai Xiao Cai Yanke Cai Zhiyan Cai Antonio Cammi Agustin Campeny chuanya Cao Guofu Cao Jun Cao Rossella Caruso Cédric Cerna jinfan Chang Yun Chang Pingping Chen Po-An Chen Shaomin Chen Shenjian Chen Xurong Chen Yi-Wen Chen Yixue Chen Yu Chen zhang Chen Jie Cheng Yaping Cheng Alexander Chepurnov Davide Chiesa Pietro Chimenti Artem Chukanov Anna Chuvashova Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Salvatore Costa Flavio Dal Corso Christophe De La Taille Jiawei Deng Zhi Deng Ziyan Deng Wilfried Depnering marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Georgy Donchenko Jianmeng dong Damien Dornic Evgeny Doroshkevich marcos Dracos Frédéric Druillole Shuxian Du Stefano Dusini martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Lukas Fajt donghua Fan Lei Fan Can Fang Jian Fang marco Fargetta Anna Fatkina Dmitry Fedoseev Vladko Fekete li-Cheng Feng Qichun Feng Richard Ford Andrey Formozov Amélie Fournier Haonan Gan Feng gao Alberto Garfagnini Alexandre Göttel Christoph Genster marco Giammarchi Agnese Giaz Nunzio Giudice Franco Giuliani maxim Gonchar Guanghua Gong hui Gong Oleg Gorchakov Yuri Gornushkin marco Grassi Christian Grewing maxim Gromov Vasily Gromov Minghao Gu Xiaofei Gu Yu Gu Mengyun Guan Nunzio Guardone maria Gul Cong Guo jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han Yan Yerevan Physics Institute YerevanArmenia Universitélibre de Bruxelles BrusselsBelgium Universidade Estadual de Londrina LondrinaBrazil Pontificia Universidade Catolica do Rio de Janeiro RioBrazil Pontificia Universidad Católica de Chile SantiagoChile Universidad Tecnica Federico Santa maria ValparaisoChile Beijing Institute of Spacecraft Environment Engineering BeijingChina Beijing Normal University BeijingChina China Institute of Atomic Energy BeijingChina Institute of High Energy Physics BeijingChina North China Electric Power University BeijingChina School of Physics Peking UniversityBeijingChina Tsinghua University BeijingChina University of Chinese Academy of Sciences BeijingChina Jilin University ChangchunChina College of Electronic Science and Engineering National University of Defense TechnologyChangshaChina Chongqing University ChongqingChina dongguan University of Technology DongguanChina jinan University GuangzhouChina Sun Yat-Sen University GuangzhouChina Harbin Institute of Technology HarbinChina University of Science and Technology of China HefeiChina The Radiochemistry and Nuclear Chemistry Group in University of South China HengyangChina Wuyi University JiangmenChina Shandong University JinanChina Institute of Modern Physics Chinese Academy of SciencesLanzhouChina Nanjing University NanjingChina Guangxi University NanningChina East China University of Science and Technology ShanghaiChina School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghaiChina Tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghaiChina Institute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesShijiazhuangChina Nankai University TianjinChina Wuhan University WuhanChina Xi’an Jiaotong University Xi’anChina Xiamen University XiamenChina School of Physics and Microelectronics Zhengzhou UniversityZhengzhouChina Institute of Physics National Chiao-Tung University Hsinchu National United University Miao-Li Department of Physics National T

The Jiangmen Underground Neutrino Observatory(JUNO)features a 20 kt multi-purpose underground liquid scintillator sphere as its main *** of JUNO's features make it an excellent location for^8B solar neutrino measurements,such as its low-energy threshold,high energy resolution compared with water Cherenkov detectors,and much larger target mass compared with previous liquid scintillator *** this paper,we present a comprehensive assessment of JUNO's potential for detecting^8B solar neutrinos via the neutrino-electron elastic scattering process.A reduced 2 MeV threshold for the recoil electron energy is found to be achievable,assuming that the intrinsic radioactive background^(238)U and^(232)Th in the liquid scintillator can be controlled to 10^(-17)g/*** ten years of data acquisition,approximately 60,000 signal and 30,000 background events are *** large sample will enable an examination of the distortion of the recoil electron spectrum that is dominated by the neutrino flavor transformation in the dense solar matter,which will shed new light on the inconsistency between the measured electron spectra and the predictions of the standard three-flavor neutrino oscillation *** m^(2)_(21)=4.8times10^(-5);(7.5times10^(-5))eV^(2),JUNO can provide evidence of neutrino oscillation in the Earth at approximately the 3sigma(2sigma)level by measuring the non-zero signal rate variation with respect to the solar zenith ***,JUNO can simultaneously measureDelta m^2_(21)using^8B solar neutrinos to a precision of 20% or better,depending on the central value,and to sub-percent precision using reactor antineutrinos.A comparison of these two measurements from the same detector will help understand the current mild inconsistency between the value of Delta m^2_(21)reported by solar neutrino experiments and the KamLAND experiment.

关键词： neutrino oscillation solar neutrino JUNO

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沙颍河流域人为输入对水体水化学组成的影响

生态学杂志 2021年第2期40卷 427-441页

作者：吴洋洋刘运涛张东李川李玉红邹霜朱双双黄兴宇麻冰涓河南理工大学资源环境学院河南焦作454000 河南省地质矿产勘查开发局第五地质勘查院郑州450001 河南省水文地质应用工程技术研究中心郑州450001

人类活动输入影响河流水体化学组成,增加经河流体系向海洋输出物质的通量,影响全球物质循环过程。有效识别人为输入的影响途径和范围对于量化人类活动对全球物质循环的影响具有重要作用。沙颍河是淮河上游最大支流,流域水体受人为输入... 详细信息

人类活动输入影响河流水体化学组成,增加经河流体系向海洋输出物质的通量,影响全球物质循环过程。有效识别人为输入的影响途径和范围对于量化人类活动对全球物质循环的影响具有重要作用。沙颍河是淮河上游最大支流,流域水体受人为输入影响严重,通过研究沙颍河流域强人为输入对河水水化学组成的影响过程,有利于弄清楚强烈人为活动干扰下河流输出物质通量的变化。本文通过平水期(2019年12月)采集河水(n=41)以及地下水样品(n=12),分析其水化学及氢氧同位素组成,阐明人为输入影响方式和途径以及在空间上的分布规律,辨别控制水体化学组成的主要因素。结果表明:沙颍河支流河水和地下水阴离子以HCO_(3)^(-)为主,阳离子以Ca2^(+)为主,干流河水逐渐转变为阴离子以Cl^(-)为主,阳离子以Na^(+)为主的水体水化学类型;碳酸盐岩和硅酸盐岩化学风化、城市工业和生活污水以及农业面源是控制流域水体化学组成的主要因素。多数沙河河水以及上游颍河河水水化学组成主要受岩石化学风化为主,少受工业废水及生活污水影响,贾鲁河和沙颍河干流河水受城市工业及生活污水影响,流域地下水普遍受到农业面源的影响;研究区地下水氯碱指数小于0,与硅酸盐岩矿物中K^(+)和Na^(+)与水体中Ca2^(+)和Mg2^(+)发生阳离子交换有关。沙颍河干流河水水体K^(+)和Na^(+)含量高于地下水,除地下水补给河水部分K^(+)和Na^(^(+))外,工业废水和生活污水输入的K^(+)和Na^(+)是沙颍河干流河水K^(+)和Na^(+)含量升高的主要原因;沙颍河干流河水Cl^(-)等行为保守元素含量往下游逐渐降低,与地下水补给和下游闸坝畜水稀释有关,而水体氘盈余值持续升高,显示下游河水经历强烈蒸发过程。本研究阐明了强人为输入对河水的影响,为沙颍河流域水污染治理提供了科学依据。

关键词：沙颍河水化学氢氧同位素人为输入淮河

浙江省一起由桶装水所致的诺如病毒胃肠炎暴发调查

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中华流行病学杂志 2011年第8期32卷 800-803页

作者：沈纪川林君芬高洁姚文婷闻栋刘光涛韩建康马会来张丽杰朱保平中国疾病预防控制中心中国现场流行病学培训项目北京100050 广州市疾病预防控制中心浙江省疾病预防控制中心湖州市疾病预防控制中心

目的调查浙江省某学校出现多名急性胃肠炎病例的感染来源、传播途径和危险因素。方法可疑病例定义：2010年4月19—30日，该校学生和教职员工中出现腹泻（〉／3次／天）或呕吐者。确诊病例为可疑病例中用RT-PCR方法检出诺如病毒阳性者。... 详细信息

目的调查浙江省某学校出现多名急性胃肠炎病例的感染来源、传播途径和危险因素。方法可疑病例定义：2010年4月19—30日，该校学生和教职员工中出现腹泻（〉／3次／天）或呕吐者。确诊病例为可疑病例中用RT-PCR方法检出诺如病毒阳性者。开展病例对照研究，以流行高峰期21--23日的220例病例作为病例组，按年级1：1比例频数匹配，随机抽取同年级无症状的学生作为对照组，比较两组饮用桶装水类型、饮水习惯和饮用量、卫生习惯的差异。结果该校学生罹患率为20．3％（312／1536），教职员工无病例。98．6％的病例（n=217）和85．5％的对照（n=188）曾饮用过教室桶装水（OR。=12．3，95％C1：3．7～40．9）；其中47．9％的病例（n：104）和41．5％的对照（n=78）饮用过教室桶装水的冷水（ORM-H=3．8，95％CI：1．5～9．6）；47．9％的病例（n=104）和48．4％的对照（n=91）饮用过教室桶装水的冷热混合水（ORM-H=2．8，95％CI：1．1．7．0）。未开封的教室桶装水菌落总数和大肠菌群严重超标。3例病例的粪便及1份未开封的教室桶装水标本检出诺如病毒Ⅱ型核酸阳性。桶装水生产厂家属无证非法生产。结论本次暴发疫情由诺如病毒污染的教室桶装山泉水引起。建议学校停用桶装水、提供开水及非法生产厂家停止生产。

关键词：诺如病毒水源性暴发病例对照研究

紫甘薯叶总黄酮对四氯化碳致小鼠慢性肝损伤的保护作用

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食品工业科技 2011年第6期32卷 371-372,375页

作者：吕晓玲陶东川马天娇刘迎旺温娟张新伟天津科技大学食品工程与生物技术学院天津300457

通过腹腔注射7%的CCl4制备慢性肝损伤小鼠模型,分别用3种不同浓度的紫甘薯叶总黄酮(FPSPL)进行治疗,检测小鼠肝脏指数(li),血清谷丙转氨酶(ALT)和谷草转氨酶(AST)活性,白蛋白(ALB)和总蛋白(TP)含量,肝组织匀浆超氧化物歧化酶(SOD)活性... 详细信息

通过腹腔注射7%的CCl4制备慢性肝损伤小鼠模型,分别用3种不同浓度的紫甘薯叶总黄酮(FPSPL)进行治疗,检测小鼠肝脏指数(li),血清谷丙转氨酶(ALT)和谷草转氨酶(AST)活性,白蛋白(ALB)和总蛋白(TP)含量,肝组织匀浆超氧化物歧化酶(SOD)活性和丙二醛(MDA)含量,研究了FPSPL对小鼠慢性肝损伤的保护作用。结果表明,FPSPL能显著降低小鼠li,降低血清ALT和AST活性,提高血清ALB和TP含量,提高肝组织SOD活性,降低MDA含量。FPSPL对四氯化碳导致的小鼠慢性肝损伤具有保护作用。

关键词：紫甘薯叶总黄酮 CCl4 慢性肝损伤

The Cymbidium genome reveals the evolution of unique morphological traits

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Horticulture Research 2021年第1期8卷 3449-3463页

作者： Ye Ai Zhen li Wei-Hong Sun juan Chen Diyang zhang liang ma Qing-Hua zhang Ming-Kun Chen Qing-dong Zheng Jiang-Feng liu Yu-Ting Jiang Bai-Jun li Xuedie liu Xin-Yu Xu Xia Yu Yu Zheng Xing-Yu liao Zhuang Zhou Jie-Yu Wang Zhi-Wen Wang Tai-Xiang Xie Shan-Hu ma Jie Zhou Yu-Jie Ke Yu-Zhen Zhou Hsiang-Chia Lu Ke-Wei liu Feng-Xi Yang Gen-Fa Zhu Laiqiang Huang dong-hui Peng Shi-Pin Chen Siren Lan Yves Van de Peer Zhong-Jian liu Key Laboratory of National Forestry and Grassland Administration for Orchid Conservation and Utilization at College of Landscape Architecture Fujian Agriculture and Forestry UniversityFuzhouChina Department of Plant Biotechnology and Bioinfor matics Ghent UniversityGentBelgium VIB Center for Plant Systems Biology GentBelgium College of Forestry Fujian Agriculture and Forestry UniversityFuzhouChina management Office of Yushan Scenic Area FuzhouChina College of Agriculture and Biotechnology Zhejiang UniversityHangzhouChina Key Laboratory of Plant Resource Conservation and Sustainable Utilization South China Botanical GardenChinese Academy of SciencesGuangzhouChina PubBio-Tech WuhanChina Tsinghua-Berkeley Shenzhen Institute(TBSI) Center for Biotechnology and Biomedicine and Shenzhen Key Laboratory of Gene and Antibody The rapyState Key Laboratory of Chemical OncogenomicsState Key Laboratory of Health Sciences and TechnologyInstitute of Biopha rmaceutical and Health Engineering(iBHE)Shenzhen International Graduate SchoolTsinghua UniversityShenzhenChina Guangdong Key Laboratory of Ornamental Plant Germplasm Innovation and Utilization Environmental Horticulture Research InstituteGuangdong Academy of Agricultural SciencesGuangzhouChina Department of Biochemistry Genetics and MicrobiologyUniversity of PretoriaPretoriaSouth Africa College of Horticulture Academy for Advanced Interdisciplinary StudiesNanjing Agricultural UniversityNanjingChina Henry Fok College of Biology and Agriculture Shaoguan UniversityShaoguanChina Institute of Vegetable and Flowers Shandong Academy of Agricultural SciencesJinanChina

The marvelously diverse Orchidaceae constitutes the largest family of *** genus Cymbidium in Orchidaceae is well known for its unique vegetation,floral morphology,and flower scent ***,a chromosomescale assembly of the genome of Cymbidium ensifolium(Jianlan)is *** genomic analysis showed that *** has experienced two whole-genome duplication(WGD)events,the most recent of which was shared by all orchids,while the older event was the t event shared by most *** results of maDS-box genes analysis provided support for establishing a unique gene model of orchid flower development regulation,and flower shape mutations in *** were shown to be associated with the abnormal expression of maDS-box *** most abundant floral scent components identi fied included methyl jasmonate,acacia alcohol and linalool,and the genes involved in the floral scent component network of *** were ***,the decreased expression of photosynthesis-antennae and photosynthesis metabolic pathway genes in leaves was shown to result in colorful striped leaves,while the increased expression of maDS-box genes in leaves led to perianth-like *** results provide fundamental insights into orchid evolution and diversi fication.

关键词： traits evolution establishing

Sub-percent precision measurement of neutrino oscillation parameters with JUNO

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Chinese Physics C 2022年第12期46卷 28-49页

作者： Angel Abusleme Thomas Adam Shakeel Ahmad Rizwan Ahmed Sebastiano Aiello Muhammad Akram Abid Aleem Fengpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde marcondes de André Didier Auguste Weidong Bai Nikita Balashov Wander Baldini Andrea Barresi Davide Basilico Eric Baussan marco Bellato Antonio Bergnoli Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Jose Busto Ilya Butorov Anatael Cabrera Barbara Caccianiga Hao Cai Xiao Cai Yanke Cai Zhiyan Cai Riccardo Callegari Antonio Cammi Agustin Campeny chuanya Cao Guofu Cao Jun Cao Rossella Caruso Cédric Cerna Chi Chan jinfan Chang Yun Chang Guoming Chen Pingping Chen Po-An Chen Shaomin Chen Xurong Chen Yixue Chen Yu Chen Zhiyuan Chen Zikang Chen Jie Cheng Yaping Cheng Yu Chin Cheng Alexey Chetverikov Davide Chiesa Pietro Chimenti Artem Chukanov Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Flavio Dal Corso Olivia Dalager Christophe De La Taille Zhi Deng Ziyan Deng Wilfried Depnering marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Dmitry Dolzhikov Georgy Donchenko Jianmeng dong Evgeny Doroshkevich marcos Dracos Frédéric Druillole Ran Du Shuxian Du Stefano Dusini martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri donghua Fan Lei Fan Jian Fang Wenxing Fang marco Fargetta Dmitry Fedoseev Zhengyong Fei li-Cheng Feng Qichun Feng Richard Ford Amélie Fournier Haonan Gan Feng gao Alberto Garfagnini Arsenii Gavrikov marco Giammarchi Nunzio Giudice maxim Gonchar Guanghua Gong hui Gong Yuri Gornushkin Alexandre Göttel marco Grassi Vasily Gromov Minghao Gu Xiaofei Gu Yu Gu Mengyun Guan Yuduo Guan Nunzio Guardone Cong Guo jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han Yang Han Miao He Wei He Tobias Heinz Patrick Hellmuth Yuekun Heng Rafael Herrera YuenKeung Ho Yerevan Physics Institute YerevanArmenia Universiélibre de Bruxelles BrusselsBelgium Universidade Estadual de Londrina LondrinaBrazil Pontificia Universidade Catolica do Rio de Janeiro Rio de JaneiroBrazil Pontificia Universidad Católica de Chile SantiagoChile Universidad Tecnica Federico Santa maria ValparaisoChile Beijing Institute of Spacecraft Environment Engineering BeijingChina Beijing Normal University BeijingChina China Institute of Atomic Energy BeijingChina Institute of High Energy Physics BeijingChina North China Electric Power University BeijingChina School of Physics Peking UniversityBeijingChina Tsinghua University BeijingChina University of Chinese Academy of Sciences BeijingChina Jilin University ChangchunChina College of Electronic Science and Engineering National University of Defense TechnologyChangshaChina Chongqing University ChongqingChina dongguan University of Technology DongguanChina jinan University GuangzhouChina Sun Yat-Sen University GuangzhouChina Harbin Institute of Technology HarbinChina University of Science and Technology of China HefeiChina The Radiochemistry and Nuclear Chemistry Group in University of South China HengyangChina Wuyi University JiangmenChina Shandong University JinanChinaand Key Laboratory of Particle Physics and Particle Irradiation of Ministry of EducationShandong UniversityQingdaoChina Institute of Modern Physics Chinese Academy of SciencesLanzhouChina Nanjing University NanjingChina Guangxi University NanningChina East China University of Science and Technology ShanghaiChina School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghaiChina Tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghaiChina Institute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesShijiazhuangChina Nankai University TianjinChina Wuhan University WuhanChina Xi'an Jiaotong University Xi'anChina Xiamen University XiamenChina School of Physics and Microelectronics Zhengzhou UniversityZhengzhou

JUNO is a multi-purpose neutrino observatory under construction in the south of *** publication presents new sensitivity estimates for the measurement of the △m_(31)^(2),△m_(21)^(2),sin^(2)θ_(12),and sin^(2)θ_(13) oscillation parameters using reactor antineutrinos,which is one of the primary physics goals of the *** sensitivities are obtained using the best knowledge available to date on the location and overburden of the experimental site,the nuclear reactors in the surrounding area and beyond,the detector response uncertainties,and the reactor antineutrino spectral shape constraints expected from the TAO satellite *** is found that the △m_(21)^(2) and sin^(2)θ_(12) oscillation parameters will be determined to 0.5%precision or better in six years of data *** the same period,the △m_(31)^(2) parameter will be determined to about 0.2%precision for each mass ordering *** new precision represents approximately an order of magnitude improvement over existing constraints for these three parameters.

关键词： neutrino oscillation reactor antineutrino precision measurement JUNO

抑酸药对胃蛋白酶原和胃泌素17诊断胃癌的影响

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山东大学学报（医学版） 2012年第2期50卷 70-73,77页

作者：尹作花王立水张欣张旭华王玎董召刚王丽丽王顺杜鲁涛李娟刘慧王传新山东大学齐鲁医院检验科济南250012 山东大学第二医院检验科济南250033

目的探讨抑酸药质子泵抑制剂(PPIs)和H2受体拮抗剂(H2RAs)对血清胃蛋白酶原(PGs,包括PGⅠ和PGⅡ)、胃泌素17(G-17)诊断胃癌的影响。方法分别采用化学发光微粒子免疫检测法和EliSA法检测190例受检者血清PGs和G-17(其中胃癌组102例、癌前... 详细信息

目的探讨抑酸药质子泵抑制剂(PPIs)和H2受体拮抗剂(H2RAs)对血清胃蛋白酶原(PGs,包括PGⅠ和PGⅡ)、胃泌素17(G-17)诊断胃癌的影响。方法分别采用化学发光微粒子免疫检测法和EliSA法检测190例受检者血清PGs和G-17(其中胃癌组102例、癌前病变组30例和对照组58例),并计算比值PGⅠ/PGⅡ(PGR)及G-17/PGⅠ(GPR)。结果各胃病组内服用PPIs患者的血清PGⅠ、PGⅡ和G-17水平显著高于未用药患者(P0.05);服用H2RAs对各指标无明显影响(P>0.05)。胃癌组总体的PGR和GPR分别低于或高于其他两组(P<0.05)。PGR和GPR诊断胃癌的ROC-AUC分别为0.836和0.720,最佳界值分别为5.9和90,灵敏度分别为76.5%和60.8%,特异度均为70.5%。结论 PPIs使血清PGs和G-17升高,PPIs或H2RAs对比值PGR和GPR均无影响;PGR和GPR可用于抑酸药干扰人群胃癌的诊断。

关键词：胃肿瘤癌前病变血清胃蛋白酶原类胃泌素类质子泵抑制剂

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化腐再生法治疗糖尿病足肌腱坏死

中国实验方剂学杂志 2012年第12期18卷 276-281页

作者：张朝晖徐强马静刘现周朱朝军卢旭亚孙玉芝李品川彭娟殷玥田影孙俊超天津中医药大学第二附属医院中医外科天津300150

目的:观察化腐再生法对糖尿病足坏死肌腱的化除及对伤口愈合的影响。方法:107例糖尿病足患者,随机分为化腐再生组35例,化腐组36例,再生组36例,针对其创面情况适时行蚕食清创,而后分别采用不同药物换药治疗,观察8周后坏死肌腱脱落、伤口... 详细信息

目的:观察化腐再生法对糖尿病足坏死肌腱的化除及对伤口愈合的影响。方法:107例糖尿病足患者,随机分为化腐再生组35例,化腐组36例,再生组36例,针对其创面情况适时行蚕食清创,而后分别采用不同药物换药治疗,观察8周后坏死肌腱脱落、伤口愈合状况以及治疗前后血常规分析中白细胞、C反应蛋白等炎性指标的变化。同时在治疗0,3,7,14 d分别提取伤口分泌物进行病理涂片以及肿瘤坏死因子-α(TNF-α)、白介素-6(IL-6)检测,观察3种换药方法对糖尿病创面愈合的影响,并加以分析。结果:化腐再生组坏死肌腱治疗后较其他两组脱落明显;3组白细胞及C反应蛋白均呈下降趋势,化腐再生组下降迅速,与其他组比较差异有统计学意义(P<0.05);分泌物病理涂片化腐再生组及化腐组炎细胞较再生组明显减少;3组分泌物TNF-α均呈上升趋势,化腐再生组较其他3组升高,差异有统计学意义(P<0.05);3组分泌物IL-6在早期均呈先升后降趋势,化腐再生组分泌物IL-6值较其他组上升时间及回落时间较其他组迅速,差异有统计学意义(P<0.05)。结论:应用化腐再生法换药,能够尽早液化坏死肌腱及坏死组织,促进创面的愈合,其机制可能与菠萝蛋白酶在象皮生肌膏联合作用下使创面引流通畅,激活并增强机体持久的抗炎免疫机制,从而利于控制糖尿病足感染,促进创面的愈合有关。

关键词：化腐再生糖尿病足菠萝蛋白酶象皮生肌膏临床研究