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Communication network designing:Transmission capacity,cost and scalability

Science china(Information Sciences) 2012年第11期55卷 2454-2465页

作者： zhang guoqiang1,2,3.& zhang guoqing1 1institute of computing technology,chinese {3. of Sciences,beijing 100190,china 2School of Computer Science and technology,Nanjing Normal University,Nanjing 210046,china 3.rovincial Key Laboratory for Computer Information Processing technology,Soochow University,Suzhou 215000,china institute of computing technology Chinese Academy of Sciences Beijing China School of Computer Science and technology Nanjing Normal University Nanjing China Provincial Key Laboratory for Computer Information Processing technology Soochow University Suzhou China

Despite the growing number of works centering around the traffic dynamics on complex networks,these researches still have some common shortcomings,e.g.,too simple traffic flow model and lack of considerations for the designing cost and scalability *** paper builds on a more realistic traffic flow model,and offers a holistic view on the network designing *** addition to the extensively studied transmission capacity,this paper takes designing cost and scalability as two other designing objectives,and presents a quantitative study of how different designing choices independently and collectively influence these objectives by the introduction of a cartesian coordinate *** is shown that different kinds of network topologies display different shapes of achievable solution spaces and exhibit different abilities to achieve cost-effective and scalable *** particular,we find the philosophy underlying empirical network designing and engineering today fails to meet the cost-effective and scalable designing requirements,and propose a cost-effective and scalable designing scheme for BA-like networks,i.e.,the efficient routing combined with effective betweenness based link bandwidth *** addition,when designing a thoroughly new network from the beginning,we find that ER network is a good candidate to achieve cost-effective and scalable designing in most settings.

关键词： cost-effective communication network designing network transmission efficiency network topology traffic dynamics next generation network scalable network designing

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Efficacy and safety of CM3.0 in moderate-to-severe atopic dermatitis:A multicenter,randomized,double-blind,placebo-controlled phase 2b trial

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chinese Medical Journal 2024年第2期137卷 200-208页

作者： Yan Zhao Jianzhong zhang Bin Yang Jingyi Li Yangfeng Ding Liming Wu Litao zhang Jinyan Wang Xiaohong Zhu Furen zhang Xiaohua Tao Yumei Li Chunlei zhang Linfeng Li Jianyun Lu Qingchun Diao Qianjin Lu Xiaoyong Man Fuqiu Li Xiujuan Xia Hao Cheng Yingmin Jia guoqing Zhao Jinchun Yan Bo Chen Department of Dermatology Peking University People’s HospitalBeijing 100044China Department of Dermatology Dermatology HospitalSouthern Medical UniversityGuangzhouGuangdong 510091China Department of Dermatology West China HospitalSichuan UniversityChengduSichuan 610041China Department of Dermatology Shanghai Skin Disease HospitalInstitute of PsoriasisTongji University School of MedicineShanghai 200443China Department of Dermatology Affiliated Hangzhou First People’s HospitalZhejiang University School of MedicineHangzhouZhejiang 310006China Department of Dermatology Tianjin Academy of Traditional Chinese Medicine Affiliated HospitalTianjin 300120China Department of Dermatology Ningbo No.2 HospitalNingboZhejiang 315010China Department of Dermatology The Wuxi Second Affiliated Hospital of Nanjing Medical UniversityWuxiJiangsu 214002China Shandong Provincial Hospital for Skin Diseases&Shandong Provincial institute of Dermatology and Veneorology Shandong First Medical University&Shandong Academy of Medical SciencesJinanShandong 250022China Center for Plastic&Reconstructive Surgery Department of DermatologyZhejiang Provincial People’s Hospital(Affiliated People’s HospitalHangzhou Medical College)HangzhouZhejiang 310014China Department of Dermatology Affiliated Hospital of Jiangsu UniversityZhenjiangJiangsu 212001China Department of Dermatology Peking University Third HospitalBeijing 100191China Department of Dermatology Beijing Friendship HospitalCapital Medical UniversityBeijing 100050China Department of Dermatology The Third Xiangya Hospital of Central South UniversityChangshaHunan 410013China Department of Dermatology Chongqing Traditional Chinese Medicine HospitalChongqing 400011China Hunan Key Laboratory of Medical Epigenomics Department of DermatologyThe Second Xiangya Hospital of Central South UniversityChangshaHunan 410011China Department of Dermatology The Second Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiang 310009China Departme

Background:Atopic dermatitis(AD)affects approximately 10%of adults ***3.0 is a humanized monoclonal antibody targeting interleukin-4 receptor alpha that blocks interleukin-4 and interleukin-13.*** trial aimed to evaluate the efficacy and safety of CM3.0 in chinese adults with moderate-to-severe ***:This multicenter,randomized,double-blind,placebo-controlled,phase 2b trial was conducted in 21 medical institutions in china from February to November *** 120 eligible patients were enrolled and randomized(1:1:1)to receive subcutaneous injections of 3.0 mg CM3.0,150 mg CM3.0,or placebo every 2 weeks for 16 weeks,followed by an 8-week follow-up *** primary endpoint was the proportion of patients achieving≥75%improvement in the Eczema Area and Severity Index(EASI-75)score from baseline at week *** and pharmacodynamics were also ***:At week 16,the proportion of EASI-75 responders from baseline was significantly higher in the CM3.0 groups(70%[28/40]for high-dose and 65%[26/40]for low-dose)than that in the placebo group(20%[8/40]).The differences in EASI-75 response rate were 50%(high ***,95%CI 3.%-69%)and 45%(low ***,95%CI 26%-64%),with both P values3.0 at both doses also significantly improved the EASI score,Investigator’s Global Assessment score,daily peak pruritus Numerical Rating Scale,AD-affected body surface area,and Dermatology Life Quality Index compared with ***3.0 treatment reduced levels of thymus and activation-regulated chemokine,total immunoglobulin E,lactate dehydrogenase,and blood *** incidence of treatment-emergent adverse events(TEAEs)was similar among all three groups,with the most common TEAEs reported being upper respiratory tract infection,atopic dermatitis,hyperlipidemia,and *** severe adverse events were deemed to be attributed to ***:CM3.0 at 150 mg and 3.0 mg every 2 weeks demonstrated significant efficacy and was well-tol

关键词： CM3.0 Moderate-to-severe atopic dermatitis Interleukin-4 receptor alpha Adults

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Simulation of aerodynamic performance affected by vortex generators on blunt trailing-edge airfoils

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Science china(Technological Sciences) 2010年第1期53卷 1-7页

作者： YANG Ke1,2,zhang Lei1,3.& XU JianZhong1,2 1 institute of Engineering Thermophysics,{3. academy of Sciences,beijing 100190,china 2 Key Laboratory of Wind Energy Utilization,{3. academy of Sciences,beijing 100190,china 3.Graduate School of {3. academy of Sciences,beijing 100190,china institute of Engineering Thermophysics Chinese Academy of Sciences Beijing China Key Laboratory of Wind Energy Utilization Chinese Academy of Sciences Beijing China Graduate School of chinese academy of Sciences Beijing China

An investigation was carried out by numerical simulation on a wind turbine airfoil and a blunt trailing-edge airfoil with and without vortex generators (VGs), and the performance of the airfoils was analyzed. By the simulation of airfoil DU 91-W2-250 it was verified that the numerical method and model were credible. Based on this airfoil, a new one with a blunt trailing edge of 6% chord was blended by symmetrically adding thickness, and its characteristics curves were obtained through computing at key angles of attack. Additionally, the pressure distribution on blended airfoil was analyzed by comparing to the airfoil without blend. The interaction of streamwise vortices induced by VGs with trailing vortex or separation vortex was considered, followed by the uncovery of how VGs can suppress the boundary layer separation.

关键词： vortex generators airfoil blunt trailing-edge

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A Cross-matching Service for Data Center of Xinjiang Astronomical Observatory

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Research in Astronomy and Astrophysics 2024年第1期24卷 119-127页

作者： Hai-Long zhang Jie Wang Xin-Chen Ye Wan-Qiong Wang Jia Li Ya-Zhou zhang Xu Du Han Wu Ting zhang Xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 830011China Key Laboratory of Radio Astronomy Chinese Academy of SciencesNanjing 210008China National Astronomical Data Center Beijing 100101China University of chinese academy of Sciences Beijing 100049China

Cross-matching is a key technique to achieve fusion of multi-band astronomical catalogs. Due to different equipment such as various astronomical telescopes, the existence of measurement errors, and proper motions of the celestial bodies, the same celestial object will have different positions in different catalogs, making it difficult to integrate multi-band or full-band astronomical data. In this study, we propose an online cross-matching method based on pseudo-spherical indexing techniques and develop a service combining with high performance computing system(Taurus) to improve cross-matching efficiency, which is designed for the Data Center of Xinjiang Astronomical Observatory. Specifically, we use Quad Tree Cube to divide the spherical blocks of the celestial object and map the 2D space composed of R.A. and decl. to 1D space and achieve correspondence between real celestial objects and spherical patches. Finally, we verify the performance of the service using Gaia 3.and PPMXL catalogs. Meanwhile, we send the matching results to VO tools-Topcat and Aladin respectively to get visual results. The experimental results show that the service effectively solves the speed bottleneck problem of crossmatching caused by frequent I/O, and significantly improves the retrieval and matching speed of massive astronomical data.

关键词： virtual observatory tools astronomical databases:miscellaneous catalogs

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Identifying heavy hitters in high-speed network monitoring

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Science china(Information Sciences) 2010年第3期53卷 659-676页

作者： zhang Yu1, FANG BinXing1,2 & zhang YongZheng2 1Research Center of Computer Network and Information Security technology, Harbin {3. of technology, Harbin 150001, china 2Research Center of Information Security, {3. of computing technology, chinese academy of Sciences, beijing 100190, china Research Center of Computer Network and Information Security technology Harbin Institute of Technology Harbin China Research Center of Information Security Institute of Computing Technology Chinese Academy of Sciences Beijing China

Identifying heavy hitters in a network traffic stream is important for a variety of network applications ranging from traffic engineering to anomaly detection such as detection of denial-of-service attacks. Existing methods generally examine newly arriving items in the stream, perform a small number of operations using a small amount of memory, and still provide guarantees on the identifying accuracy. In high-speed network monitoring, the update speed per item is extremely critical. However, so far as we know, there are no identifying algorithms which can provide constant update time (O(1)) in a weighted data stream. In this paper, we present an algorithm named Weighted Lossy Counting (WLC) which is able to identify heavy hitters in a high-speed weighted data stream with constant update time. WLC employs a novel efficient partially ordered data structure which is able to provide a fast per-item update speed while keeping the memory cost relatively low. We compare WLC with state-of-the-art algorithms for finding heavy hitters in real traffic traces. The experimental results show that WLC performs well in accuracy (recall, precision and average relative error) as other algorithms; moreover it has a much higher update speed at the cost of relatively larger memory space used. A theoretical worst-case memory bound of WLC is also derived in this paper; however, experiments with long real traffic traces show that WLC requires much less space than the theoretical bound in practice.

关键词： network traffic monitoring heavy hitter weighted data streams

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P2P traffic optimization

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Science china(Information Sciences) 2012年第7期55卷 1475-1492页

作者： zhang guoqiang 1,2 ,TANG MingDong 3.,CHENG SuQi 2,4 ,zhang {3. 2 ,SONG HaiBin 5 ,CAO JiGuang 6 & YANG Jing 7 1 School of Computer Science and technology,Nanjing Normal University,Nanjing 210046,china 2 institute of computing technology,chinese academy of Sciences,beijing 100190,china 3.School of Computer Science and Engineering,Hunan University of Science and technology,Xiangtan 411201,china 4 Graduate University of chinese academy of Sciences,beijing 100190,china 5 Nanjing R&D Center,Huawei Technologies,Nanjing 210012,china 6 china academy of Telecommunication Research of MIIT,beijing 100191,china 7 china Mobile Research institute,beijing 100053.china School of Computer Science and technology Nanjing Normal University Nanjing China institute of computing technology Chinese Academy of Sciences Beijing China School of Computer Science and Engineering Hunan University of Science and Technology Xiangtan China Graduate University of chinese academy of Sciences Beijing China Nanjing R&D Center Huawei Technologies Nanjing China china academy of Telecommunication Research of MIIT Beijing China china Mobile Research institute Beijing China

Peer-to-peer (P2P) based content distribution systems have emerged as the main form for content distribution on the Internet,which can greatly reduce the distribution cost of content providers and improve the overall system ***,the mismatch between the overlay and underlay networks causes large volume of redundant traffic,which intensifies the tension between P2P content providers and ***,how to efficiently use network resources to reduce the traffic burden on the ISPs is crucial for the sustainable development of P2P *** paper surveys the state-of-art P2P traffic optimization technologies from three perspectives:P2P cache,locality-awareness and data *** details,comparison between these technologies and their applicabilities are presented,followed by a discussion of the issues that remain to be addressed and the direction of future content distribution research.

关键词： P2P traffic localization P2P traffic optimization P2P cache locality-awareness network coding content-centric network

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Analysis of moment invariants under general linear transformation

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Science china(Information Sciences) 2010年第7期53卷 1305-1311页

作者： DIAO LuHong1, LI Hua2, zhang Sen1 & LIU Lei1 1College of Applied Sciences, beijing University of technology, beijing 100124, china 2National Center of Intelligent computing, institute of computing technology, chinese academy of Science, beijing 100080, china College of Applied Sciences Beijing University of Technology Beijing China National Center of Intelligent computing Institute of Computing Technology Chinese Academy of Science Beijing China

This paper presents the necessary and sufficient condition of moment invariants under general linear transformation. Based on this condition, arbitrary order and dimensional moment invariant sets can be constructed. D... 详细信息

关键词： moment invariants independence linear transformation

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涡轮导叶压力面分区域复合角气膜冷却特性

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航空动力学报 2024年第3期39卷 42-51页

作者：张深李国庆刘浩康忠张燕峰卢新根中国科学院工程热物理研究所北京100190 中国科学院大学航空宇航学院北京100049 华北电力大学能源动力与机械工程学院北京102206

针对通道二次流造成涡轮叶片压力面气膜轨迹发生偏转的现象,提出了沿展向分区域布置复合角的设计概念。以高压涡轮导叶HS1A为研究对象,采用数值模拟的方法,在出口雷诺数为2.3.10^(5)的工况下,分析了二次流、复合角和吹风比对气膜冷却... 详细信息

针对通道二次流造成涡轮叶片压力面气膜轨迹发生偏转的现象,提出了沿展向分区域布置复合角的设计概念。以高压涡轮导叶HS1A为研究对象,采用数值模拟的方法,在出口雷诺数为2.3.10^(5)的工况下,分析了二次流、复合角和吹风比对气膜冷却特性的影响。结果表明:近端区二次流产生的径向潜流具有促进气膜展向覆盖的能力,相较于叶中区提高了气膜孔出口下游的冷却效率,但也会加剧射流和主流的掺混,减小气膜的有效覆盖长度;针对不同展向区域的二次流大小,精细化布置各区域的气膜孔复合角,可以将气膜轨迹的偏转角度全部修正为0°,同时将平均气膜冷却效率提升了10.42%;复合角冷却模型在吹风比为0.5~1.0时具有较好的范围适用性,吹风比增大至1.3.气膜轨迹会发生反向偏转。

关键词：涡轮导叶气膜冷却通道二次流分区域复合角气膜冷却效率

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Multiparty simultaneous quantum identity authentication with secret sharing

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Science china(Physics,Mechanics & Astronomy) 2008年第3期51卷 321-327页

作者： YANG YuGuang1,2,WEN QiaoYan3.& zhang Xing4,5 1 College of Computer Science and technology,{3. University of technology,{3. 100022,china 2 State Key Laboratory of Information Security (Graduate University of the chinese academy of Sciences),{3. 100049,china 3.School of Science,{3. University of Posts and Telecommunications,{3. 100876,china 4 institute of Electronic technology,Information Engineering University,Zhengzhou 450004,china 5 Trusted computing Laboratory,{3. University of technology,{3. 100022,china College of Computer Science and technology Beijing University of Technology Beijing China State Key Laboratory of Information Security (Graduate University of the chinese academy of Sciences) Beijing China School of Science Beijing University of Posts and Telecommunications Beijing China institute of Electronic technology Information Engineering University Zhengzhou China Trusted computing Laboratory Beijing University of Technology Beijing China

Two multiparty simultaneous quantum identity authentication (MSQIA) protocols based on secret sharing are presented. All the users can be authenticated by a trusted third party (TTP) simultaneously. In the first protocol,the TTP shares a random key K with all the users using quantum secret sharing. The ith share acts as the authentication key of the ith user. When it is necessary to perform MSQIA,the TTP generates a random number R secretly and sends a sequence of single photons encoded with K and R to all the users. According to his share,each user performs the corresponding unitary operations on the single photon sequence sequentially. At last,the TTP can judge whether the impersonator exists. The sec-ond protocol is a modified version with a circular structure. The two protocols can be efficiently used for MSQIA in a network. They are feasible with current technol-ogy.

关键词： quantum identity authentication secret sharing quantum cryptography

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Observation constraints of the hard X-ray modulation telescope HXMT

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Science china(Physics,Mechanics & Astronomy) 2010年第S1期53卷 31-35页

作者： LU Yu1,2,zhang WenZhao3.QU JinLu1,SONG LiMing1,GAO Jian3.zhang HongMei4 & OU Ge4 1 Key Laboratory of Particle Astrophysics,institute of High Energy Physics,{3. academy of Sciences,beijing 100049,china 2 Graduate University of {3. academy of Sciences,beijing 100049,china 3.Department of Astronomy,beijing Normal University,beijing 100875,china 4 computing Center,institute of High Energy Physics,{3. academy of Sciences,beijing 100049,china Key Laboratory of Particle Astrophysics Institute of High Energy Physics Chinese Academy of Sciences Beijing China Graduate University of chinese academy of Sciences Beijing China Department of Astronomy Beijing Normal University Beijing China computing Center Institute of High Energy Physics Chinese Academy of Sciences Beijing China

The hard X-ray modulation telescope HXMT is a low orbit X-ray space telescope whose main science goals are to accomplish a hard X-ray all sky survey and to study timing and spectral characteristics of X-ray *** has three kinds of science instruments:the high energy X-ray detector(HE),the medium energy X-ray detector(ME) and the low energy X-ray detector(LE).The observation schedule of HXMT is a key to achieving the science goal of HXMT,and the analysis of the observation constraints is one of the first tasks in making the observation *** paper analyzes how the observation constraints influence the sky visibility and the visible time distribution of X-ray sources and discusses the schedule strategy with regard to the observation constraints.

关键词： HXMT observation constraints sky visibility

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