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A Note on Casoratian Solutions to Two-Dimensional Toda Lattice

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Communications in Theoretical Physics 2007年第3期47卷 390-392页

作者： zhang da-jun wu hua Department of Mathematics Shanghai University Shanghai 200444 China

In this short paper we generalize the conditions that Casoratian entries satisfy for the two-dlmenslonal Toda lattice. Although we finally conclude that our generalization is trivial in some sense for getting new solu... 详细信息

关键词： Casoratian solution two-dimensional Toda lattice bilinear

Cytoplasmic FKBPs are involved in molting and metamorphosis through regulating the nuclear localization of EcR

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Insect Science 2024年第3期31卷 759-772页

作者： Xian zhang Qiao-Ran Wang Qian wu jun Gu Li-hua huang Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology School of Life SciencesSouth China Normal UniversityGuangzhouChina Guangmeiyuan R&D Center Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied TechnologySouth China Normal UniversityMeizhouChina

Molting and metamorphosis are important physiological processes in insects that are tightly controlled by ecdysone receptor(EcR)through the 20-hydroxyecdysone(20E)signaling *** is a steroid nuclear receptor(SR).Several FK506-binding proteins(FKBPs)have been identified from the mammal SR complex,and are thought to be involved in the subcellular trafficking of ***,their roles in insects are poorly *** explore whether FKBPs are involved in insect molting or metamorphosis,we injected an FKBP inhibitor(FK506)into a lepidopteran insect,Spodoptera litura,and found that molting was inhibited in 61.11%of the larvae,and that the time for larvae to pupate was significantly extended.A total of 10 FKBP genes were identified from the genome of *** and were clustered into 2 distinct groups,according to their subcellular localization,with FKBP13 and FKBP14 belonging to the endoplasmic reticulum(ER)group and with the other members belonging to the cytoplasmic(Cy)*** the CyFKBPs were significantly upregulated in the prepupal or pupal stages,with the opposite being observed for the ER group ***506 completely blocked the transfer of EcR to the nucleus under 20E induction,and significantly downregulated the transcriptional expression of many 20E signaling genes.A similar phenomenon was observed after RNA interference of2 CyFKBPs(FKBP45 and FKBP12b),but not for *** together,our data indicate that the cytoplasmic FKBPs,especially FKBP45 and FKBP12b,mediate the nuclear localization of EcR,thereby regulating the 20E signaling and ultimately affecting molting and metamorphosis in insects.

关键词： EcR FKBP metamorphosis molting RNAi subcellular localization

Performance improvements in complementary metal oxide semiconductor devices and circuits based on fin field-effect transistors using 3-nm ferroelectric Hf_(0.5)Zr_(0.5)O_(2)

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Rare Metals 2024年第7期43卷 3242-3249页

作者： Zhao-Hao zhang Yan-Na Luo Gao-Bo Xu Jia-Xin Yao Zhen-hua wu Hong-Bin Zhao Qing-Zhu zhang hua-Xiang Yin jun Luo Wen-wu Wang Hai-Ling Tu Integrated Circuit Advanced R&D Center Institute of Microelectronics of Chinese Academy of SciencesBeijing 100029China School of Integrated Circuits University of Chinese Academy of SciencesBeijing 100049China State Key Laboratory of Advanced Materials for Smart Sensing General Research Institute for Nonferrous MetalsBeijing 100088China

In this work,a conventional HfO_(2) gate dielectric layer is replaced with a 3-nm ferroelectric(Fe) HZO layer in the gate stacks of advanced fin field-effect transistors(FinFETs).Fe-induced characteristics,e.g.,negative drain induced barrier lowering(N-DIBL) and negative differential resistance(NDR),are clearly observed for both p-and n-type HZO-based *** characteristics are attributed to the enhanced ferroelectricity of the 3-nm hafnium zirconium oxide(HZO) film,caused by Al doping from the TiAlC capping *** mechanism is verified for capacitors with structures similar to the *** to the enhanced ferroelectricity and N-DIBL phenomenon,the drain current(I_(DS))of the HZO-FinFETs is greater than that of HfO_(2)-FinFETs and obtained at a lower operating ***,circuits based on HZO-FinFET achieve higher performance than those based on HfO_(2)-FinFET at a low voltage drain(V_(DD)),which indicates the application feasibility of the HZO-FinFETs in the ultralow power integrated circuits.

关键词： FinFET Ferroelectric Hafnium zirconium oxide Subthreshold swing Low power

Alkyl Radical Initiated Cyclization/Cascade for Synthesizing Lactam-Substituted Alkyl Sulfones

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Chinese Journal of Chemistry 2024年第16期42卷 1853-1859页

作者： Li-jun wu Kai-Yi zhang Pei Yang Chuan-Chong Peng Jin-Hui Liu Qing Li da-Zhi Sun Shuangfeng Yin College of Sciences Central South University of Forestry and TechnologyChangshaHunan410004 China School of Chemistry and Chemical Engineering Inner Mongolia UniversityHohhotInner Mongolia010021 China

An alkyl radical initiated cyclization/tandem reaction of alkyl bromides and alkyl electrophiles by using potassium metabisulphite(K_(2)S_(2)O_(5))as a connector is developed for the synthesis of various lactam-substituted alkyl ***,this process does not require a metal catalyst or metal powder reductant,highlighting its environmentally friendly *** reaction demonstrates outstanding substrate adaptability and a high tolerance towards diverse functional ***,the biologically active molecules and commercially available drugs with a late-stage modification are also highly compatible with this *** studies revealed that the reaction proceeds through a single-step process involving intramolecular radical cyclization,"SO_(2)"insertion,and external alkyl incorporation.

关键词： Alkyl radical Metal-free catalyzed Cyclization/cascade Potassium metabisulphite Electrophiles Alkyl sulfones Lactams Alkyl bromides Sodium formate

A simple model for two-proton radioactivity

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Chinese Physics C 2024年第10期48卷 247-255页

作者： Jie-Dong Jiang Xiao Liu Dong-Meng zhang Ming Li Xi-jun wu Xiao-hua Li School of Nuclear Science and Technology University of South ChinaHengyang 421001China School of Math and Physics University of South ChinaHengyang 421001China National Exemplary Base for International Sci&Tech.Collaboration of Nuclear Energy and Nuclear Safety University of South ChinaHengyang 421001China Cooperative Innovation Center for Nuclear Fuel Cycle Technology&Equipment University of South ChinaHengyang 421001China Key Laboratory of Low Dimensional Quantum Structures and Quantum Control Hunan Normal UniversityChangsha 410081China

In this work,considering the preformation factor of the emitted two protons in parent nucleus S_(2p) and the effect of the parent nucleus deformation,based on the Wentzel-Kramers-Brillouin approximation and Bohr-Sommerfeld quantization condition,we improve a simple phenomenological model proposed by Bayrak[***.G:47,025102(2020)]to systematically study 2p radioactivity *** model contains two adjustable parameters V_(0) and a_(β),which are related to the depth of nuclear potential and effect of *** calculated results show that this model can effectively reproduce the experimental data with a corresponding root-mean-square(RMS)standard deviation of σ=*** comparison,we include the Gamow-like model(GLM)proposed by Liu et al.[***.C 45,044110(2021)],generalized liquid drop model(GLDM)proposed by Cui et al.[***.C 101,014301(2020)],effective liquid drop model(ELDM)proposed by *** et al.[***.B 774,14(2017)],two-potential approach with Skyrme-Hartree-Fock(TPASHF)proposed by Pan et al.[***.C 45,124104(2021)],phenomenological model with a screened electrostatic barrier(SEB)propoesed by Zou et al.[***.C 45,104101(2021)],unified fission model(UFM)proposed by Xing et al.[***.C 45,124105(2021)],Coulomb and proximity potential model for deformed nuclei(CPPMDN)proposed by Santhosh[***.C 104,064613(2021)],two-parameter empirical formula proposed by Liu et al.[***.C 45,024108(2021)],and four-parameter empirical formula proposed by Sreeja et al.[***.J.A 55,33(2019)].In addition,we use this model to 2p predict the radioactive half-lives of some possible potential nuclei whose 2p radioactivity are energetically allowed or observed but not yet quantified in NUBASE2020.

关键词： two-proton radioactivity half-lives Wentzel-Kramers-Brillouin approximation

Experimental observation of the significant difference between surface and bulk Kondo processes in Kondo lattice YbCu_(2)Si_(2)

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Science China(Physics,Mechanics & Astronomy) 2024年第4期67卷 154-160页

作者： Yin-Zou Zhao Jiao-Jiao Song Qi-Yi wu Hao Liu Chen zhang Bo Chen Hong-Yi zhang Zhen-hua Chen Yao-Bo huang Xue-Qing Ye Ya-hua Yuan Yu-Xia Duan jun He Jian-Qiao Meng School of Physics Central South UniversityChangsha 410083China Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201204China

Synchrotron-based angle-resolved photoemission spectroscopy was employed to investigate the temperature evolution of the Yb 4 f spectral for surface and bulk in the Kondo lattice YbCu_(2)Si_(2).Our study quantitatively distinguishes between the surface and bulk hybridization processes,revealing that the onset temperatures for both surface and bulk hybridization processes are significantly higher than the Kondo ***,we found that the effective surface Kondo temperature is much lower than that of the *** findings offer valuable insights into the understanding of heavy fermion physics.

关键词： Kondo lattice angle-resolved photoemission spectroscopy electronic structure hybridization surface state

Innovative coaxial high-temperature thin-film sensor with core-shell structure surpassing traditional multilayer films

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Rare Metals 2024年第8期43卷 3854-3867页

作者： Chao wu Guo-Chun Chen Fu-Xin Zhao Fan Lin Ying-jun Zeng Yan-zhang Fu Yan-Song zhang Li-da Xu Qin-Nan Chen Rui Tang dao-Heng Sun Zhen-Yin Hai Pen-Tung Sah Institute of Micro-Nano Science and Technology Xiamen UniversityXiamen 361005China AECC Shenyang Engine Institute Shenyang 110015China School of Aerospace Engineering Xiamen UniversityXiamen 361005China

High-temperature thin-film sensors(TFSs)often suffer from inadequate tolerance to elevated *** this study,an innovative approach is presented to fabricate in situ integrated TFSs with a core-shell structure on alloy components using coaxial multi-ink printing *** method replaces traditional layerby-layer(LbL) deposition and LbL sintering processes and achieves simplified one-step *** coaxial TFS includes a conductive Pt core for conducting and sensing and a dielectric shell for electrical isolation and high-temperature *** coaxial Pt resistance grid demonstrates excellent high-temperature stability,with a resistance drift rate of only 0.08%·h^(-1) at 800 ℃,significantly lower than traditional Pt *** employing this method,a Pt thin-film strain gauge(TFSG) is fabricated that boasts remarkable high-temperature electromechanical *** effectively addresses the problem of sensitivity degradation experienced by traditional LbL Pt TFSGs when subjected to high *** demonstrate the system integration potential of the technique by printing and verifying the functionality of a long-path thinfilm resistance grid on turbine blades,which can withstand butane flame up to ~1300℃.These results showcase the potential of core-shell structure of the coaxial TFS for high-temperature applications,providing a novel approach to develop high-performance TFS beyond traditional multilayer structure.

关键词： Coaxial printing Core-shell structure Thinfilm strain gauge High-temperature stability

Cyclic Dinucleotide Self-Assembled Nanoparticles as a Carrier-Free Delivery Platform for STING-Mediated Cancer Immunotherapy

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CCS Chemistry 2024年第1期6卷 177-195页

作者： Lang Zhao Shao-hua Zhuo Tian-Yang Wang jun-jun wu Jing-Yun Su Wen-Hao Li Bo-Dou zhang Yan-Mei Li Key Lab of Bioorganic Phosphorus Chemistry&Chemical Biology Department of ChemistryTsinghua UniversityBeijing 100084 Beijing Institute for Brain Disorders Beijing 100069 Center for Synthetic and Systems Biology Tsinghua UniversityBeijing 100084

Cyclic dinucleotides(CDNs)are natural agonists of the stimulator of interferon genes(STING),which is an attractive immunotherapy ***,CDNs and their derivatives are being investigated ***,the poor bioavailability of exogenous CDNs has limited their application in *** nanocarriers are widely used for cytosolic delivery of CDNs,their loading capacity is insufficient,and their complicated composition and purification process raises bio-compatibility ***,we report a super-simplified CDN self-assembly strategy for carrier-free delivery of *** the presence of excess K^(+),CDNs form oligomers which further self-assemble with divalent metal ions(such as Mn^(2+))to form nanoparticles(NPs)in aqueous *** demonstrate that the self-assembled CDN NPs promote cellular uptake of CDNs and enhance tumor immunogenicity by remodeling the tumor microenvironment,inducing immunogenic tumor cell death and increasing tumorinfiltrating lymphocytes,which is conducive to the generation of tumor neoantigen-specific T-cell *** also demonstrate that the use of CDN NPs alone or in combination with immune checkpoint blockades inhibits tumor growth,highlighting the fact that CDN NPs are a potent platform for cancer immunotherapy.

关键词： cyclic dinucleotide STING carrierfree delivery tumor immunogenicity cancer immunotherapy

CCDC181 is required for sperm flagellum biogenesis and male fertility in mice

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Zoological Research 2024年第5期45卷 1061-1072页

作者： Xiang-jun zhang Xiao-Ning Hou Jian-Teng Zhou Bao-Lu Shi Jing-Wei Ye Meng-Lei Yang Xiao-hua Jiang Bo Xu Li-Min wu Qing-hua Shi Division of Reproduction and Genetics First Affiliated Hospital of University of Science and Technology of China(USTC)Hefei National Laboratory for Physical Sciences at MicroscaleSchool of Basic Medical SciencesDivision of Life Sciences and MedicineBiomedical Sciences and Health Laboratory of Anhui ProvinceInstitute of Health and MedicineHefei Comprehensive National Science CenterUniversity of Science and Technology of ChinaHefeiAnhui 230001China

The structural integrity of the sperm flagellum is essential for proper sperm *** defects can result in male infertility,yet the precise mechanisms underlying this relationship are not fully ***181,a coiled-coil domain-containing protein,is known to localize on sperm flagella and at the basal regions of motile *** this knowledge,the specific functions of CCDC181 in flagellum biogenesis remain *** this study,Ccdc181 knockout mice were *** absence of CCDC181 led to defective sperm head shaping and flagellum ***,the Ccdc181 knockout mice exhibited extremely low sperm counts,grossly aberrant sperm morphologies,markedly diminished sperm motility,and typical multiple morphological abnormalities of the flagella(MMAF).Additionally,an interaction between CCDC181 and the MMAF-related protein LRRC46 was identified,with CCDC181 regulating the localization of LRRC46 within sperm *** findings suggest that CCDC181 plays a crucial role in both manchette formation and sperm flagellum biogenesis.

关键词： Male infertility CCDC181 MMAF Spermiogenesis Flagellum biogenesis