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Dendritic Learning-Incorporated Vision Transformer for Image Recognition

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IEEE/CAA Journal of Automatica Sinica 2024年第2期11卷 539-541页

作者： Zhiming zhang Zhenyu Lei Masaaki Omura Hideyuki Hasegawa Shangce Gao Faculty of Engineering University of ToyamaToyama-shi 930-8555Japan IEEE

Dear Editor,This letter proposes to integrate dendritic learnable network architecture with Vision Transformer to improve the accuracy of image *** this study,based on the theory of dendritic neurons in neuroscience,we design a network that is more practical for engineering to classify visual *** on this,we propose a dendritic learning-incorporated vision Transformer(DVT),which out-performs other state-of-the-art methods on three image recognition benchmarks.

关键词： Image network image

Lidocaine hydrochloride loaded isomaltulose microneedles for efficient local anesthesia of the skin

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Chinese Chemical Letters 2024年第4期35卷 298-302页

作者： Xuebing Jiang Siyi Wang Li zhang Xian Jiang Maling Gou State Key Laboratory of Biotherapy West China HospitalSichuan UniversityChengdu 610041China Huahang Microcreate Technology Co. Ltd.Chengdu 610042China Department of Dermatology West China HospitalSichuan UniversityChengdu 610041China

Lidocaine hydrochloride(LIDH) as an anesthetic is widely used in local anesthesia. Dissolving microneedles(MNs) have great application value in the field of skin anesthesia. However, the limited drug-loading of dissolving MNs is an existing challenge that affects clinical use. In this study, we have screened isomaltulose(ISO) as the proper matrix material for the MNs by using molecular dynamics(MD) simulation. Our findings indicate that ISO has good compatibility with LIDH, and the LIDH-loaded ISO MNs(LI-MNs) have high drug-loading capacity. The drug-loading capacity of LI-MNs could reach 80%, and it could effectively puncture the skin. In addition, the preparation method of customized LI-MNs was established based on three-dimensional(3D) printing technology. It was shown that the administration time of LI-MNs could be controlled within 3 min. Also, the LI-MNs were able to provide the local anesthetic efficacy within2 min and sustained for more than 2 h. Significantly, LI-MNs had more efficient drug efficacy compared to the topical creams and the majority of existing LIDH-loaded dissolving MNs. They even provided a longer duration of action than the injections. Overall, the LI-MNs with high drug-loading have a promising application prospect.

关键词： Microneedles Local anesthesia Lidocaine hydrochloride Isomaltulose Transdermal delivery

Nonalternant isomer of pentacene fusing two azulene units

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Chinese Chemical Letters 2024年第5期35卷 244-248页

作者： Bo Yu Pengchen Du Jianwen Guo Hanshen Xin Jianhua zhang Department of Chemistry College of SciencesShanghai UniversityShanghai 200444China School of Microelectronics Shanghai UniversityShanghai 201800China

Azulene is a promising building block for creating innovative polycyclic aromatic hydrocarbons. This study involved the construction of three nonalternant isomers of pentacene by fusing two azulene units, named Az-PH1/2/3. Az-PH1 was initially developed through the rhodium(Ⅱ)-catalyzed cyclization of bis(N-tosylhydrazone)s. Intriguingly, Az-PH1 was also unexpectedly obtained during a nickel(0)-catalyzed one-step tandem reaction. We investigated the optical and electrochemical properties, aromaticity, and photo-oxidative stability of Az-PH1, comparing it with the well-known pentacene using density functional theory, electrochemical, and photophysical tests. Our results showed that the azulene-fusing strategy resulted in a molecule with narrow optical bandgaps(2.046 eV) and a long half-life time under ambient air conditions.

关键词： Azulene Isomer Polycyclic aromatic hydrocarbon Nickel(0)-catalyzed Photo-oxidative stability

Identification of different degrees of processed ginger using GC-IMS combined with machine learning

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Journal of Pharmaceutical Analysis 2024年第1期14卷 149-151页

作者： Shuang Liu Hongjing Dong Minmin zhang Wei Geng Xiao Wang Key Laboratory for Applied Technology of Sophisticated Analytical Instruments of Shandong Province Shandong Analysis and Test CenterQilu University of Technology(Shandong Academy of Sciences)Jinan250014China Key Laboratory for Natural Active Pharmaceutical Constituents Research in Universities of Shandong Province School of Pharmaceutical SciencesQilu University of Technology(Shandong Academy of Sciences)Jinan250014China Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University Jinan250014China

Ginger,the rhizomes of Zingiber officinale Roscoe,was a wellknown edible plant species commonly used in China,which has pungent flavor[1].Ginger has numerous chemical compounds,such as phenolic constituents,volatile compounds(VOCs),and polysaccharides[2].Among them,VOCs are considered one of the effective compounds in ginger due to their functional properties,including anti-inflammatory,antioxidant,and analgesic[3].

关键词： phenolic edible rhizome

Integrating Shipborne Images with Multichannel Deep Learning for Landslide Detection

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Journal of Earth Science 2024年第1期35卷 296-300页

作者： Pengfei Feng Changdong Li Shuang zhang Jie Meng Jingjing Long School of Mechanical Engineering and Electronic Information China University of GeosciencesWuhan 430074China Faculty of Engineering China University of GeosciencesWuhan 430074China Department of civil Badong National Observation and Research Station of Geohazards China University of GeosciencesWuhan 430074China College of Geology Engineering and Geomatics Changan UniversityXi'an 710054China Department of Geosciences University of OsloOslo 0316Norway

0 *** disasters in recession zones along riverbanks impose significant global social,economic,and ecological *** areas are particularly susceptible to *** inflict significant harm due to fluctuating water levels(Meng et al.,2023;Dai et al.,2021;Li et al.,2021).This,in turn,endangers the safety and accessibility of roads and waterways adjacent to rivers,and hydropower station and reservoir security(Yan et al.,2022;Guo et al.,2020;Tang et al.,2017).

关键词： reservoir Landslide Ship

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基于原位测试的圆砾层地基工程性质分析方法

科技创新与生产力 2024年第7期45卷 136-141页

作者：张磊朱雷次婧天水师范学院土木工程学院甘肃天水741000 中国科学院、水利部成都山地灾害与环境研究所四川成都610041 甘肃省水务投资集团有限公司甘肃兰州730030

本文对天水冲洪积圆砾层进行了多组平板载荷试验,特别针对钎探数据显示工程性质较好与较差的点进行了对比试验,总体表现为圆砾层最终沉降量较小,经分析,试验曲线不完整,未能反映出极限状态,采用该曲线确定的地基承载力偏小,圆砾层工程... 详细信息

本文对天水冲洪积圆砾层进行了多组平板载荷试验,特别针对钎探数据显示工程性质较好与较差的点进行了对比试验,总体表现为圆砾层最终沉降量较小,经分析,试验曲线不完整,未能反映出极限状态,采用该曲线确定的地基承载力偏小,圆砾层工程性质未能有效发挥。采用双曲线切线模量法计算后的p-s曲线更加完整,能较准确判断出极限承载力pu,经计算,钎探击数较小的试验点pu也能达到700 kPa,钎探击数较大的试验点pu可以达到1400 kPa,这主要与土的结构特征有关,实际开挖剖面后证明了这一点。另外,采用切线模量法计算出的实际基础尺寸下荷载沉降p-s曲线与监测数据吻合度高,说明该分析方法可靠,该分析方法确定圆砾层地基承载力及最终沉降量准确且高效。

关键词：土力学圆砾层强度承载力沉降

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Evaluating the relative importance of predictors in Generalized Additive Models using the *** R package

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Plant Diversity 2024年第4期46卷 542-546页

作者： Jiangshan Lai Jing Tang Tingyuan Li Aiying zhang Lingfeng Mao College of Ecology and Environment Nanjing Forestry UniversityNanjing210037China Research Center of Quantitative Ecology Nanjing Forestry UniversityNanjing 210037China University of Chinese Academy of Sciences Beijing100049China Guangzhou Climate and Agro-meteorology Center Guangzhou 511430China Guangdong Ecological Meteorological Center Guangzhou 510640China

Generalized Additive Models(GAMs)are widely employed in ecological research,serving as a powerful tool for ecologists to explore complex nonlinear relationships between a response variable and ***,evaluating the relative importance of predictors with concurvity(analogous to collinearity)on response variables in GAMs remains a *** address this challenge,we developed an R package named *** calculates individual R^(2) values for predictors,based on the concept of'average shared variance',a method previously introduced for multiple regression and canonical *** these individual R^(2)s,which add up to the overall R^(2),researchers can evaluate the relative importance of each predictor within *** illustrate the utility of the *** package by evaluating the relative importance of emission sources and meteorological factors in explaining ozone concentration variability in air quality data from London,*** believe that the *** package will improve the interpretation of results obtained from GAMs.

关键词： Average shared variance Coefficient of determination Commonality analysis GAMs Hierarchical partitioning Individual R^(2)

Trifluoromethyl enable high-performance single-emitter white organic light-emitting devices based on quinazoline acceptor

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Chinese Chemical Letters 2024年第4期35卷 442-446页

作者： Xiangan Song Shaogang Shen Mengyao Lu ying Wang Yong zhang School of Materials Science and Engineering Harbin Institute of TechnologyHarbin 150001China Key Laboratory of Photochemical Conversion and Optoelectronic Materials and TIPC-CityU Joint Laboratory of Functional Materials and DeviceChinese Academy of SciencesTechnical Institute of Physics and ChemistryBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China

Single-emitter white organic light-emitting diode(WOLED) based on small organic molecule exhibits great potential in simplifying fabrication process of WOLEDs. However, the design and synthesis of molecule for highly efficient single-emitter WOLED still remains a challenge. Herein, two asymmetric donor-acceptor-acceptor'(D-A-A') type molecule(PTZ-PQ-F and PTZ-PQ-CF3) are developed by employing trifluoromethyl(CF_(3)) or fluorine atom as secondary acceptor, which can exhibit white lighting with dual emission bands consisting of blue traditional fluorescence from quasi-axial(ax) conformer and orange thermally activated delayed fluorescence(TADF) from quasi-equatorial(eq) conformer. The introduction of CF_(3) into PTZ-PQ-CF3 greatly enhanced the photoluminescence quantum yield(PLQY) by suppressing the nonradiative deactivation. Owing to electron-inductive-effect of CF3, the “eq” conformer of PTZ-PQCF3 exhibits a much smaller ΔESTof 0.01 e V to realize more efficient reverse intersystem crossing(RISC)process, and then enhance the exciton utilization(nearly 100%) of the whole dual emission system. Consequently, single-emitter WOLEDs based on PTZ-PQ-CF3 show nearly standard white emission with EQE of 13.0% and ciE of(0.35, 0.36) in m CP host and show warm white emission with high EQE of 25.5%and ciE of(0.40, 0.47) in 35 Dcz PPy host, which are the best performance among reported single-emitter WOLEDs.

关键词： Single-emitter white organic light-emitting diode Conformational isomerism Thermally activated delayed fluorescence Trifluoromethyl Exciton utilization

Knee osteoarthritis:A review of animal models and intervention of traditional Chinese medicine

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Animal Models and Experimental Medicine 2024年第2期7卷 114-126页

作者： Xuyu Song ying Liu Siyi Chen Lei zhang Huijie zhang Xianhui Shen Hang Du Rong Sun Orthopaedic trauma surgery The Second Hospital of Shandong UniversityJinanShandongChina Academy of Traditional Chinese Medicine Tianjin University of Traditional Chinese MedicineTianjinChina Department of Traditional Chinese Medicine The Second Hospital of Shandong UniversityJinanShandongChina College of pharmacy Shandong University of Traditional Chinese MedicineJinanShandongChina The Second Clinical College of Shandong University Shandong UniversityJinanShandongChina Advanced Medical Research Institute Shandong UniversityJinanShandongChina The Second Hospital of Shandong University JinanShandongChina

Background:Knee osteoarthritis(KOA)characterized by degeneration of knee cartilage and subsequent bone hyperplasia is a prevalent joint condition primarily affecting aging *** pathophysiology of KOA remains poorly understood,as it involves complex mechanisms that result in the same ***,researchers are interested in studying KOA and require appropriate animal models for basic *** herbal compounds,which consist of multiple herbs with diverse pharmacological properties,possess characteristics such as multicomponent,multipathway,and multitarget *** potential benefits in the treatment of KOA continue to attract ***:This study aims to provide a comprehensive overview of the advantages,limitations,and specific considerations in selecting different species and methods for KOA animal *** will help researchers make informed decisions when choosing an animal ***:Online academic databases(e.g.,PubMed,Google Scholar,Web of Science,and CNKI)were searched using the search terms“knee osteoarthritis,”“animal models,”“traditional Chinese medicine,”and their combinations,primarily including KOA studies published from 2010 to ***:Based on literature retrieval,this review provides a comprehensive overview of the methods of establishing KOA animal models;introduces the current status of advantages and disadvantages of various animal models,including mice,rats,rabbits,dogs,and sheep/goats;and presents the current status of methods used to establish KOA animal ***:This study provides a review of the animal models used in recent KOA research,discusses the common modeling methods,and emphasizes the role of traditional Chinese medicine compounds in the treatment of KOA.

关键词： animal models knee osteoarthritis system review traditional Chinese medicine