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Bidirectional regulation of the brain-gut-microbiota axis following traumatic brain injury

Neural Regeneration Research 2025年第8期20卷 2153-2168页

作者： Xinyu You Lin Niu Jiafeng Fu Shining Ge Jiangwei Shi yanjun zhang Pengwei Zhuang National Key Laboratory of Chinese Medicine Modernization Tianjin University of Traditional Chinese MedicineTianjinChina Haihe Laboratory of Modern Chinese Medicine Tianjin University of Traditional Chinese MedicineTianjinChina First Teaching Hospital of Tianjin University of Traditional Chinese Medicine TianjinChina National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion TianjinChina

Traumatic brain injury is a prevalent disorder of the central nervous *** addition to primary brain parenchymal damage,the enduring biological consequences of traumatic brain injury pose long-term risks for patients with traumatic brain injury;however,the underlying pathogenesis remains unclear,and effective intervention methods are *** dysfunction is a significant consequence of traumatic brain *** the most densely innervated peripheral tissue in the body,the gut possesses multiple pathways for the establishment of a bidirectional“brain-gut axis”with the central nervous *** gut harbors a vast microbial community,and alterations of the gut niche contribute to the progression of traumatic brain injury and its unfavorable prognosis through neuronal,hormonal,and immune pathways.A comprehensive understanding of microbiota-mediated peripheral neuroimmunomodulation mechanisms is needed to enhance treatment strategies for traumatic brain injury and its associated *** comprehensively reviewed alterations in the gut microecological environment following traumatic brain injury,with a specific focus on the complex biological processes of peripheral nerves,immunity,and microbes triggered by traumatic brain injury,encompassing autonomic dysfunction,neuroendocrine disturbances,peripheral immunosuppression,increased intestinal barrier permeability,compromised responses of sensory nerves to microorganisms,and potential effector nuclei in the central nervous system influenced by gut ***,we reviewed the mechanisms underlying secondary biological injury and the dynamic pathological responses that occur following injury to enhance our current understanding of how peripheral pathways impact the outcome of patients with traumatic brain *** review aimed to propose a conceptual model for future risk assessment of central nervous system-related diseases while elucidating novel insights into the bidirectional effec

关键词： traumatic brain injury brain-gut-microbiome axis gut microbiota neuroimmune immunosuppression host defense vagal afferents bacterial infection dorsal root ganglia nociception neural circuitry

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Design and Fabrication of a Multi-electrode Metal-core Piezoelectric Fiber and Its Application as an Airflow Sensor

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Journal of Bionic Engineering 2016年第3期13卷 416-425页

作者： Yixiang Bian yanjun zhang Xianlong Xia College of Mechanical Engineering YangZhou University Yangzhou 225127 China

Crickets, similar to some other insects, have highly sensitive filiform hairs on their cerci that can detect miniscule changes in airflow. This study imitates the perception mechanism of these filiform sensory hairs of crickets by designing and fabricating a Multi-electrode Metal Core Piezoelectric Fiber （MMPF）-based airflow sensor. Four longitudinal conductive sheets were coated symmetrically on their surfaces with Metal-core Piezoceramic Fibers （MPF）. The four fan-shaped piezoelectric ceramics with surface electrode covers were polarized. After successful polarization, the cantilevered MMPF could be used as an airflow sensor. The four electrodes on the surface were symmetrically divided into two groups. Therefore, two signals can be produced by a single fiber sensor. The theoretical model of an MMPF airflow sensor has been established. The model indicates that the ratio of the two signals is equivalent to the tangent of the airflow angle. Furthermore, the sum of the squares of the two signals is not dependent on the angle, but reflects the velocity of the airflow. Therefore, a single MMPF can be used to measure both the direction and amplitude for a given airflow. The theoretical model has been confirmed via experimental measurements.

关键词： biomimetic sensor piezoelectric fiber airflow sensor artificial hair directional sensitivity

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Higher-order properties and extensions for indirect MRAC and APPC of linear systems

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Science China(Information Sciences) 2024年第4期67卷 218-238页

作者： yanjun zhang Zhipeng zhang Jian SUN Lei WANG Kangkang zhang National Key Lab of Autonomous Intelligent Unmanned Systems Beijing Institute of Technology Beijing Institute of Technology Chongqing Innovation Center College of Control Science and Engineering Zhejiang University Department of Electrical and Electronic Engineering Imperial College London KIOS Research and Innovation Center of Excellence University of Cyprus

Recently, a reference derived some new higher-order output tracking properties for direct model reference adaptive control(MRAC) of linear time-invariant(LTI) systems: limt→∞ e~((i))(t) = 0, i = 1,..., n~*-1, where n~* and e~((i))(t) denote the relative degree of the system and the i-th derivative of the output tracking error, respectively. However, a naturally arising question involves whether indirect adaptive control(including indirect MRAC and indirect adaptive pole placement control) of LTI systems still has higher-order tracking properties. Such properties have not been reported in the literature. Therefore, this paper provides an affirmative answer to this question. Such higher-order tracking properties are new discoveries since they hold without any additional design conditions and, in particular, without the persistent excitation condition. Given the higher-order properties, a new adaptive control system is developed with stronger tracking features.(1) It can track a reference signal with any order derivatives being unknown.(2) It has higher-order exponential or practical output tracking properties.(3) Finally, it is different from the usual MRAC system, whose reference signal’s derivatives up to the n~* order are assumed to be known. Finally, two simulation examples are provided to verify the theoretical results obtained in this paper.

关键词： higher-order tracking indirect adaptive control model reference adaptive control adaptive pole placement control

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Adaptive PI Control Based Stability Margin Configuration of Aircraft Control Systems with Unknown System Parameters and Time Delay

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Journal of Systems Science & Complexity 2024年第4期37卷 1507-1525页

作者： zhang Zhibing ZHOU Dapeng WANG Yeguang GAO Wanxin zhang yanjun AVIC Shenyang Aircraft Design and Research Institute Shenyang 110035China School of Automation Beijing Institute of TechnologyBeijing 100081China State Key Lab of Autonomous Intelligent Unmanned Systems Beijing Institute of TechnologyBeijing 100081China

The stability margin is a vital indicator for assessing the safety level of aircraft control *** should maintain sufficient stability margin to ensure safety during flight,especially in the process of large maneuver *** stability margin is generally quantified by the Bode diagram,which strictly depends on the system parameters and the open-loop transfer ***,due to the uncertain flight environments,transmission delays of sensors and mode switchings,etc.,there exist large parameter and structure uncertainties in the aircraft control systems,which make it difficult to precisely configure the stability margin to the desired value by the usual control *** address this problem,an indirect adaptive control strategy is proposed in this paper,where an adaptive PI control law with the capability of self-configuration of stability margin is *** developed control law not only achieves stable time-varying command tracking in the time domain,but also is able to automatically configure the phase margin and gain margin in the frequency ***,the simulation of the one-degree-of-freedom roll rate control model of the air vehicle verifies the validity of the proposed control method.

关键词： Adaptive control aircraft control parameter uncertainty stability margin configuration

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Three-Stages Hyperspectral Image Compression Sensing with Band Selection

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Computer Modeling in Engineering & Sciences 2023年第1期134卷 293-316页

作者： Jingbo zhang yanjun zhang Xingjuan Cai Liping Xie Taiyuan University of Science and Technology Taiyuan030024China

Compressed sensing(CS),as an efficient data transmission method,has achieved great success in the field of data transmission such as image,video and *** can robustly recover signals from fewer Measurements,effectively alleviating the bandwidth pressure during data ***,CS has many shortcomings in the transmission of hyperspectral image(HSI)*** work aims to consider the application of CS in the transmission of hyperspectral image(HSI)data,and provides a feasible research scheme for CS of HSI *** has rich spectral information and spatial information in bands,which can reflect the physical properties of the *** of the hyperspectral image compressed sensing(HSICS)algorithms cannot effectively use the inter-band information of HSI,resulting in poor reconstruction *** this paper,A three-stage hyperspectral image compression sensing algorithm(Three-stages HSICS)is proposed to obtain intra-band and inter-band characteristics of HSI,which can improve the reconstruction accuracy of ***,we establish a multi-objective band selection(Mop-BS)model,amulti-hypothesis prediction(MHP)model and a residual sparse(ReWSR)model for HSI,and use a staged reconstruction method to restore the compressed *** simulation results show that the three-stage HSICS successfully improves the reconstruction accuracy of HSICS,and it performs best among all comparison algorithms.

关键词： Combinatorial optimization band selection hyperspectral image compressed sensing

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Present Situation of the Anti-Fatigue Processing of High-Strength Steel Internal Thread Based on Cold Extrusion Technology:A Review

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Chinese Journal of Mechanical Engineering 2017年第2期30卷 231-240页

作者： Hong MIAO Cheng JIANG Sixing LIU Shanwen zhang yanjun zhang College of Mechanical Engineering Yangzhou UniversityYangzhou 225009China Key Laboratory of Modem Agricultural Equipment Nanjing Research Institute for Agricultural Mechanization Ministry of AgricultureNanjing 210014China

The adoption of cold-extrusion forming for internal thread net forming becomes an important component of anti-fatigue processing with the development of internal thread processing towards high performance, low cost and low energy consumption. It has vast application foreground in the field of aviation, spaceflight, high speed train and etc. The internal thread processing and anti-fatigue manufacture technology are summarized. In terms of the perspective of processing quality and fatigue serving life, the advantages and disadvantages of the processing methods from are compared. The internal thread cold-extrusion processing technology is investigated for the purpose of improving the anti-fatigue serving life of internal thread. The superiorities of the plastic deformation law and surface integrity of the metal layer in the course of cold extrusion for improving its stability and economy are summed up. The proposed research forecasts the develop- ment tendency of the internal thread anti-fatigue manufacturing technology.

关键词： High-strength steel · Internal thread · Coldextrusion · Anti-fatigue · Surface integrity

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小米椒生物力学特性试验研究

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农机化研究 2025年第4期47卷 151-159页

作者：张善文孙永元张永吉戴敏缪宏张燕军高吉成扬州大学机械工程学院江苏扬州225009 江苏里下河地区农业科学研究所江苏扬州225007

为了提升小米椒的机械化收获质量和效率,对小米椒的物理及力学特性进行了试验测量。通过测量,小米椒在15天内的含水率为86%~90%,且中部最高、首部次之、尾部最低。通过拉伸试验,确定小米椒断裂时的抗拉强度为0.679 MPa±0.03 MPa。采用... 详细信息

为了提升小米椒的机械化收获质量和效率,对小米椒的物理及力学特性进行了试验测量。通过测量,小米椒在15天内的含水率为86%~90%,且中部最高、首部次之、尾部最低。通过拉伸试验,确定小米椒断裂时的抗拉强度为0.679 MPa±0.03 MPa。采用正交旋转组合设计方法,确定了加载速度对抗压强度的影响极显著,小米椒直径对抗压强度的影响显著,加载速度对剪切强度的影响显著。通过轴向压缩和剪切试验,确定了小米椒首部的抗压强度平均值为0.62 MPa,弹性模量平均值为2.72 MPa;中部抗压强度平均值为0.64 MPa,弹性模量平均值为3.17 MPa;尾部抗压强度平均值为0.61 MPa,弹性模量平均值为2.64 MPa,小米椒剪切强度平均值为0.32 MPa。

关键词：小米椒力学特性物理特性

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Waterlogging stress in cotton:Damage, adaptability, alleviation strategies, and mechanisms

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The Crop Journal 2021年第2期9卷 257-270页

作者： yanjun zhang Guangya Liu Hezhong Dong Cundong Li Cotton Research Center Shandong Academy of Agricultural SciencesJinan 250100ShandongChina Agronomy College of Shandong Agricultural University Tai'an 271018ShandongChina Hebei Agricultural University Baoding 071001HebeiChina College of Life Sciences Shandong Normal UniversityJinan 250014ShandongChina

Over the last few decades,waterlogging stress has increasingly threatened global cotton *** results in reduced soil oxygen,impairing the growth and development of this valuable crop and often resulting in severe yield loss or crop ***,as cotton has an indeterminate growth habit,it is able to adapt to waterlogging stress by activating three mechanisms:the escape,quiescence,and self-regulating compensation *** escape mechanism includes accelerated growth,formation of adventitious roots,and production of *** quiescence mechanism involves reduced biomass accumulation and energy dissipation via physiological,biochemical,and molecular *** self-regulation compensation mechanism allows plants to exploit their indeterminate growth habit and compensatory growth ability by accelerating growth and development following relief from waterlogging *** review how the growth and development of cotton is impaired by waterlogging,focusing on the three strategies associated with tolerance and adaptation to the *** discuss agronomic measures and prospects for mitigating the adverse effects of waterlogging stress.

关键词： Abiotic stress Adaptability Agronomic measures Cotton Waterlogging

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Interference structure of shallow water reverberation in time-frequency distribution

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Science China(Physics,Mechanics & Astronomy) 2010年第8期53卷 1408-1411页

作者： LI FengHua zhang yanjun zhang RenHe LIU JianJun National Laboratory of Acoustics Institute of AcousticsChinese Academy of SciencesBeijing 100190China Graduate University of Chinese Academy of Science Beijing 100190China

The striations of the reverberation spectrum in the time-frequency distribution were observed in a shallow water acoustic experiment in 2002. A model following the coherent reverberation model developed in 2002 is presented to explain the observed striations. To examine the consistency between the measured data and numerical predictions, we have used a method based on Radon transform for determining the slope of the striations to the measured reverberation data and numerical predictions. The results indicate that the previously developed coherent reverberation model can predict the interference structure of the reverberation intensity in the time-frequency distribution.

关键词： reverberation interference time-frequency waveguide invariant

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A new mixed type crack propagation criterion in shale reservoirs

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Petroleum 2024年第1期10卷 85-92页

作者： Muru Ding Zhirong Jin yanjun zhang Jinghong Hu Beijing Key Laboratory of Unconventional Natural Gas Geology Evaluation and Development Engineering China University of GeosciencesBeijingChina Sinopec Jiangsu Oil Field Branch YangzhouChina Oil&Gas Technology Research Institute Changqing Oilefiled CompanyPetroChinaXi'anChina

Hydraulic fracturing is a mainstream technology for unconventional oil and gas reservoirs development all over the *** to use this technology to achieve high-level oil and gas resource extraction and how to form complex fracture networks as hydrocarbon transportation channels in tight reservoirs,which depends to a large extent on the interaction between hydraulic and pre-existing *** hydraulic fracturing of fractured reservoirs,the impact of natural fractures,perforation direction,stress disturbances,faults and other influencing factors will produce a mixed I&II mode hydraulic *** forecast whether hydraulic fractures cross pre-existing fractures,according to elastic mechanics and fracture mechanics,a stress state of cracks under the combination of tensile(I)and shear(II)is presented.A simple mixed-mode I&II hydraulic fracture's crossing judgment criterion is established,and the propagation of hydraulic fractures after encountering natural fractures is *** results show that for a given approaching angle there exists a certain range of stress ratio when crossing *** high approaching angle and large stress ratio,it is likely that hydraulic cracks will go directly through pre-existing *** reinitiated angle is always controlled within the range of approximately 30among the main direction of penetration.

关键词： Crack propagation criterion Stress ratio Approaching angle Reinitiated angle Mechanical model

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