检索结果-南通市图书馆

Design of supercontinuum source for coherent anti-Stokes Raman scattering microscopy

在线全文

学校读者我要写书评

暂无评论

Optoelectronics Letters 2008年第2期4卷 103-105页

作者： zhang Hui CHANG Sheng-jiang zhang yan-xin ZHAO Xiang-ting Institute of Modern Optics Key Laboratory for Optoelectronic Information Technical Science of Education Ministry of China Nankai University Tianjin 300071 China

A new method to obtain supercontinuum(SC) source for multiplex coherent anti-stokes Raman scattering (CARS) microscopy is proposed. The nonlinear propagation in photonic-crystal fibers (PCF) of femtosecond pulse laser with central wavelength at 800.9 nm is studied with scalar wave theory. Based on the incident laser power and dispersion of PCF, super broadband source for multiplex CARS microscopy is designed.

关键词：超级连续资源拉曼理论散射显微镜光纤器械

Role of Self-Coupling in Dynamics of Diluted Hopfiela Neural Networks

在线全文

学校读者我要写书评

暂无评论

Chinese Physics Letters 1996年第1期13卷 1-4页

作者： HU Bei-lai zhang yan-xin Department of Physics Nankai UniversityTianjin 300071 Institute of Modern Optics Nankai UniversityTianjin 300071

The dynamical equation of diluted Hopfield neural networks with self-couplings is calculated by analytical *** presented results show that the self-coupling strongly inUuences the dynamical behavior of the network,mak... 详细信息

关键词： networks neural Hopfield

Fluorescent competitive assay for melamine using dummy molecularly imprinted polymers as antibody mimics

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2016年第5期15卷 1166-1177页

作者： DU xin-wei zhang yan-xin SHE Yong-xin LIU Guang-yang ZHAO Feng-nian WANG Jing WANG Shan-shan JIN Fen SHAO Hua JIN Mao-jun ZHENG Lu-fei Institute of Quality Standards and Testing Technology for Agro-Products Chinese Academy of Agricultural Sciences Beijing 100081 P.R.China Key Laboratory of Agro-product Quality and Safety Beijing 100081 PR. China School of Chemical Engineering and Technology Harbin Institute of Technology Harbin 150001 P.R. China

A fluorescent competitive assay for melamine was first developed utilizing dummy molecularly imprinted polymers（DMIPs） as artificial antibodies. This method is based on the competition between fluorescent substances and the unlabeled analyte for binding sites in synthesized DMIPs and the decreased binding of fluorescent substances to DMIPs due to increased concentrations of melamine in the solutions. DMIPs for melamine were synthesized under a hot water bath in the presence of the initiator azobisisobutyronitrile（AIBN） using 2,4-diamino-6-methyl-1,3,5-triazine（DAMT） as a dummy template, methacrylic acid（MAA） as a functional monomer, and ethylene glycol dimethacrylate（EGDMA） as a crosslinking agent. The adsorption capacity and selectivity of DMIPs for melamine were evaluated by the isothermal adsorption curve and Scatchard analysis. The evaluation results showed that the synthesized DMIPs had specific recognition sites for melamine and the maximum adsorption amount was 1 066.33 μg g^（-1）. Later, 5-（4,6-d ichlorotriazinyl） amino fluorescein（DTAF） with a triazine ring, which s lightly resembles m elamine, w as selected as the fluorescent substance. The fluorescent competitive assay using DMIPs as t he antibody mimics was finally established by selecting and optimizing the reaction solvents, DMIPs amount, DTAF concentration, and incubation time. The optimal detection system showed a linear response w ithin range of 0.05-40 mg L^（-1） and the limit of detection（LOD） was 1.23 μg L^（-1）. It was successfully applied to the detection of melamine in spiked milk samples wi th satisfactory recoveries（71.9 to 86.3%）. According to the comparative analysis, the result of optimized fluorescent competitive assay re vealed excellent agreement with the HPLC-MS/MS result for melamine.

关键词： dummy molecularly imprinted polymers melamine fluorescent competitive assay artificial antibody

Synthesis,Structural Characterization of Ferrocenyl Iminophosphines and Amidophosphines as Well as Their Application in the Suzuki Reaction

在线全文

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2007年第6期23卷 683-687页

作者： GONG Jun-fang zhang yan-hui FAN xin-heng WANG Da-wei SONG Mao-ping WU yang-jie Department of Chemistry Henan Key Laboratory of Chemical Biology and Organic Chemistry Key Laboratory of Applied Chemistry of Henan Universities Zhengzhou University Zhengzhou 450052 P. R. China

Ferrocenyliminophosphine 1 and 1,1′-bisferrocenyliminophosphine 2 were easily prepared from the condensation of formylferrocene or 1,1′-diformylferrocene with 2-（diphenylphosphino） aniline. The following reduction of imine group by LiAlH4 led to the formation of the corresponding ferrocenyl amidophosphines 3 and 4. The new ligands 2- 4 were well characterized by IR, ^1H NMR, ^31p NMR spectra, elemental analysis, and ESI-MS. The catalytic activity of all the ligands with palladium compounds in the Suzuki reaction was evaluated. Ligand 1, in combination with Pd （OAc）2, was found to be the most effective for the Suzuki reaction of aryl bromides with phenylboronic acid. Typically, the use of 0. 1% （molar fraction） of Pd（OAc）2/ligand 1 in the presence of two equivalents of K2CO3 as base in toluene at 110 ℃ provided good to excellent yields of the coupled products.

关键词： Ferrocenyl Iminophosphine Amidophosphine Synthesis Suzuki reaction

Metachronous contralateral testicular and bilateral adrenal metastasis of chromophobe renal cell carcinoma:a case report and review of the literature

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2010年第5期11卷 386-389页

作者： Hai-yang WU Li-wei XU You-yun zhang yan-lan YU xin-de LI Gong-hui LI Department of Urology Sir Run Run Shaw Hospital School of Medicine Zhejiang University Hangzhou 310016 China

Chromophobe renal cell carcinoma(ChRCC) metastatic to the testis has not,to the best of our knowledge,been reported in the *** have there been reports of delayed bilateral adrenal metastasis of *** we report a case of metachronous contralateral testicular and bilateral adrenal metastasis of ChRCC in a 70-year-old man who underwent right radical nephrectomy for RCC six years *** was admitted to the hospital because of left intrascrotal enlargement of two-month *** revealed a mass in the upper pole of the left *** tomography(CT) showed irregular masses in the bilateral adrenal *** radical orchiectomy and laparoscopic bilateral adrenalectomy were *** pathologic examination showed metastatic ChRCC in the left testis and bilateral adrenal *** follow-up showed that the patient had survived for at least 56 months without *** case highlights the unique behavior of RCC with an unusual site of metastasis and favorable survival after multiple metastasectomy.

关键词： Renal cell carcinoma(RCC) Testicular metastasis Adrenal metastasis Metastasectomy

Involvement of CD4^＋CD25^＋ regulatory T cells in the pathogenesis of polycythaemia vera

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2008年第18期121卷 1781-1786页

作者： ZHAO Wen-bo LI Ying LIU xin zhang Ling-yan WANG xin Department of Hematology Shandong Provincial Hospital Affiliated to Shandong University Jinan Shandong 250021 China

Background Regulatory T cells （mreg） have been shown to play an important role in the regulation of hematopoietic activity. However, there is no information about the effect of Treg cells in the pathogenesis of polycythaemia vera （PV）. Methods In this study, we investigated the percentage and function of Treg cells in the peripheral blood of 21 PV patients and 25 healthy donors, mreg cells were identified and characterized as CD4^＋CD25^＋FOXP3^＋ by flow cytometry. The suppressive activity of CD4^＋CD25^＋ Treg cells was assessed by the proliferation and cytokine secretion of the co-cultured CD4^＋CD25^- fractions. Results The results showed that the percentage of Treg cells in the peripheral blood of PV patients significantly increased compared to healthy controls （（10.93±4.02）% vs （5.86±1.99）%, P 〈0.05）. Moreover, the mRNA and protein expression of FOXP3 was higher in CD4^＋CD25^＋ Treg cells. Coordinately, when co-cultured with the activated CD4^＋CD25^- cells, the CD4^＋CD25^＋ Treg cells showed enhanced suppressive function in PV. Yet, the underlying mechanism for the increased frequency and function of CD4^＋CD25^＋ Treg cells is still to be clarified. Conclusion Treg cells expansion might account for the abnormal T cell immunity in PV patients and thus contribute to the pathogenesis of PV.

关键词： polycythaemia vera regulatory T cells pathogenesis

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

基于进化策略的港口集装箱装船作业优化

同济大学学报（自然科学版） 2005年第3期33卷 361-365页

作者：张新艳同济大学机械工程学院上海200092

使用一种进化策略算法对港口集装箱装船作业顺序进行优化 .首先对港口集装箱码头的结构及其装船作业过程进行分析 ,针对集装箱装船作业排序问题 ,建立了考虑位置约束和设备约束等条件的优化目标函数 ,给出了目标解的染色体表达方式和基... 详细信息

使用一种进化策略算法对港口集装箱装船作业顺序进行优化 .首先对港口集装箱码头的结构及其装船作业过程进行分析 ,针对集装箱装船作业排序问题 ,建立了考虑位置约束和设备约束等条件的优化目标函数 ,给出了目标解的染色体表达方式和基于混合变异的进化机制 ,并通过实例计算和分析验证了算法的实用性 .

关键词：集装箱装船作业优化进化策略

Inhibitory effects of Zengshengping fractions on DMBA-induced buccal pouch carcinogenesis in hamsters

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2012年第2期125卷 332-337页

作者： Guan Xiao-bing Sun Zheng Chen Xiao-xin Wu Hong-ru zhang xin-yan Capital Med Univ Sch Stomatol Dept Periodontol & Oral Med Beijing 100050 Peoples R China N Carolina Cent Univ JLC BBRI Canc Res Program Durham NC 27707 USA

Background Zengshengping （ZSP） tablets had inhibitory effects on oral precancerous lesions by reducing the incidence of oral ***,the severe liver toxicity caused by systemic administration of ZSP limits the long-term use of this anti-cancer *** purpose of this study was to evaluate the tumor inhibitory effects due to the topical application of extracts from ZSP,a Chinese herbal drug,on 7,12-dimethlbenz（a）anthracene （DMBA） induced oral tumors in *** study also investigated the anti-cancer mechanisms of the ZSP extracts on oral *** DMBA （0.5%） was applied topically to the buccal pouches of Syrian golden hamsters （6-8 weeks old） three times per week for six weeks in order to induce the development of oral *** fractions of ZSP were either applied topically to the oral tumor lesions or fed orally at varying dosages to animals with oral tumors for 18 *** volume was measured by histopathological *** cell proliferation was evaluated by counting BrdU labeled cells and by Western blotting for mitogen-activated protein kinase （MAPK） protein *** protein levels of apoptosis marker Caspase-3 and regulator Bcl-2 protein were also measured by Western *** Topical application of DMBA to the left pouch of hamsters induced oral tumor *** treated with DMBA showed a loss in body weight while animals treated with ZSP maintained normal body *** the ZSP n-butanol fraction and water fraction significantly reduced tumor volume by 32.6% （P 〈0.01） and 22.9% （P 〈0.01）*** application of ZSP also markedly decreased the BrdU-positive cell numbers in oral tumor lesions and reduced the expression level of *** addition,ZSP promoted tumor cell apoptosis by increasing Caspase-3 expression but decreasing Bcl-2 protein *** The n-butanol and water fractions of ZSP are effective at inhibiting tumor cell proliferation and stimulating apoptosis in ora

关键词： Zengshengping chemoprevention oral cancer, proliferation apoptosis

Tectonic evolution and the analysis of unfavorable geology in a tunnel

在线全文

学校读者我要写书评

暂无评论

Journal of Coal Science & Engineering(China) 2009年第4期15卷 374-381页

作者： WANG Jin-shan WANG Li LI Yong zhang yan-xin CAO Zhi-gang LI Chun-liu Hebei Normal University of Science ＆ Technology Qinhuangdao 066004 China yanshan University Qinhuangdao 066004 China

Based on the theory of geomechanics and using geologic analytical methods,analyed the fault characteristics, mechanical properties, displacement mode, tectonic system, structural pattern, activity mode of stress, tectonic activity, and tectonic evolution ofthe area of the Xiamen submarine tunnel, the strike NWW 295^(。), which is the main unfavorable geological structure that affects the safety of the tunnel construction; the macrogeological prediction concludes that weathered troughs and groundwater-rich zonesformed by its larger-scale fault fracture zones are the main unfavorable geological bodiesprovides a basis for preventing the geo-logical hazards in the tunnel construction.

关键词： tunnel tectonic evolution unfavorable geological body macro geological prediction geological analytical method