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面向聚变中子探测的宽禁带半导体探测器关键问题与研究挑战

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电子学报 2024年第8期52卷 2933-2938页

作者：苏凯张金风张逸韵蒋树庆郭辉张进成郝跃西安电子科技大学集成电路学部宽禁带半导体器件与集成技术全国重点实验室陕西西安710071 西安电子科技大学宽禁带半导体国家工程研究中心陕西西安710071 中国科学院半导体研究所北京100083 中国工程物理研究院核物理与化学研究所四川绵阳621900

近年来国际聚变反应研究获得重大进展,选择抗位移能力强的宽禁带半导体探测器是推动聚变研究的关键技术之一.金刚石超宽禁带半导体具备卓越抗辐照和时间响应等特性,是聚变诊断特别是高能中子诊断的理想材料,碳化硅宽禁带半导体也可测量... 详细信息

近年来国际聚变反应研究获得重大进展,选择抗位移能力强的宽禁带半导体探测器是推动聚变研究的关键技术之一.金刚石超宽禁带半导体具备卓越抗辐照和时间响应等特性,是聚变诊断特别是高能中子诊断的理想材料,碳化硅宽禁带半导体也可测量中子,且大尺寸外延技术更成熟,可覆盖聚变研究装置上的大规模应用.通过这两种宽禁带半导体辐射探测器的研究并实现自主可控的高性能器件制备,将显著提高我国核聚变反应测量系统的性能,支持我国在未来的全球能源革命中处于领先优势.本文将对这两种宽禁带半导体探测器在聚变中子探测应用场景下研制的关键问题和研究挑战进行探讨,助力我国聚变能源开发和应用.

关键词：中子探测器金刚石碳化硅能量分辨脉冲响应

“两个结合”视域下中国特色社会主义协商文化的培育路径

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怀化学院学报 2024年第2期43卷 1-6页

作者：张金成傅慧平中共江西省委党校江西南昌330108

中国特色社会主义协商文化是马克思主义民主理论、交流思想等与中国具体实际、中华传统协商文化结合的产物,形成于中国共产党百年来革命、建设、改革过程中的民主政治实践。“两个结合”不仅是培育中国特色社会主义协商文化的根本遵循,... 详细信息

中国特色社会主义协商文化是马克思主义民主理论、交流思想等与中国具体实际、中华传统协商文化结合的产物,形成于中国共产党百年来革命、建设、改革过程中的民主政治实践。“两个结合”不仅是培育中国特色社会主义协商文化的根本遵循,丰富了培育协商文化的逻辑内涵,更从坚持共同思想基础、实现中华传统协商文化创造性转化与发展,以及发挥专门协商机构作用等方面为中国特色社会主义协商文化指明了培育方向。

关键词：民主政治协商民主 “两个结合” 中国特色社会主义协商文化中华传统协商文化

Effects of alternating magnetic field on the corrosion rate and corrosion products of copper

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Rare Metals 2008年第3期27卷 324-328页

作者： GUO Bin zhang Peng jin Yongping cheng Shukang School of Materials Science and Engineering Harbin Institute of Technology Harbin 150001 China Institute of Electromagnetic and Electronic Technology Harbin Institute of Technology Harbin 150001 China

The effects of alternating magnetic field on the corrosion morphologies, corrosion rate, and corrosion products of copper in 3.5% NaCl solution, sea water, and magnetized sea water were investigated using electrochemical test, scanning electron microscopy/energy dispersive analysis system of X-ray （SEM/EDAX）, and X-ray diffraction （XRD）. The results show that the corrosion rate of copper in magnetized sea water is minimal. Moreover, the surface of the specimen in magnetized sea water is uniform and compact as compared with those in 3.5% NaCl solution and sea water. The corrosion products of copper in magnetized sea water are mainly Cu2O and CuCl2. However, the corrosion products in sea water are CuCl, Cu2Cl（OH）3, and FeCl3-6H2O. The electrochemical corrosion mechanisms of copper in the three media were also discussed.

关键词： corrosion sea water alternating magnetic field copper corrosion products

Inhibitive effect of IL-24 gene on CD133^+ laryngeal cancer cells

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Asian Pacific Journal of Tropical Medicine 2014年第11期7卷 867-872页

作者： jin-zhang cheng Dan Yu Hui zhang Chun-Shun jin Yan Liu Xue Zhao Xin-Meng Qi Xueshi-Bojie Liu Second Affiliated Hospital of Jilin University

Objective:To explore the inhihitive and apoptosis inductive effect of IL-24 genes on CD133^+laryngeal cancer cells in Hep-2 ***:Human peripheral blood monocytes were *** total RNA was extracted by using Trizol method and reverse transcripted into cDNA using RT-PCR *** P1 and P2 was designed for the amplification of human IL-24 *** confirmation of agarose gel electrophoresis tests,TA was cloned into pMD19-T simple *** Ⅰ and Xho Ⅰ double digesting human IL-24 and pIRES2-ZsGreen1 and eukaryotic expression vector were used to establish the pIRES2-ZsGreen1-hIL-24 vector,and detected by enzyme digestion and gene sequencing *** cytometry(FCM) was used to isolate CD133^+ cells from Hep-2 ***133^+ cells were transfected with pIRES2-ZsGreen1-hIL-24 through liposome *** detection,MTT and FCM were used to observe the effect of IL-24 gene on CD133^+ laryngeal cancer Hep-2 ***:Lipotin mediated transfection of recombinant pIRES2-ZsGreen1-hIL-24 plasmid into CD133^+ Hep-2 could expressed IL-24 gene in cells *** results showed that IL-24 transfected group was significantly suppressed compared to empty vector group and control group(P<0.05);FCM results showed that the apoptosis rate of experimental group increased significantly compared to empty vector group and control group(P<0.05).Conclusions:IL-24 gene expressions can inhibit proliferation of CD133^+laryngeal cells in Hep-2 line and promote their apoptosis.

关键词： IL-24 CD133 Laryngeal cancer Cancer stem cells Gene therapy

Simulation and Experimentation for Low Density Drain AlGaN/GaN HEMT

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Chinese Physics Letters 2014年第3期31卷 177-180页

作者： WANG Chong HE Yun-Long DING Ning ZHENG Xue-Feng zhang Peng MA Xiao-Hua zhang jin-cheng HAO Yue Key Lab of Wide Band Gap Semiconductor Materials and Devices and Institute of Microelectronics Xidian University Xi'an 710071

In order to improve the breakdown voltage of AlGaN/GaN high electron mobility transistors （HEMTs）, we report a feasible method of low density drain （LDD） HEMT. The fluoride-based plasma treatment using CF4 gas is performed on the drain-side of the gate edge. The channel two-dimensional electron gas （2DEG） concentrations are modulated by fluoride plasma treatment, and the peak electric field at the gate edge is effectively reduced, so the breakdown voltage is improved. The electric field distributions of the LDD-HEMTs are simulated using the Silvaco software, and the peak of the electric field on the gate edge is effectively reduced. Experimental results show that, compared with the conventional HEMT, LDD-HEMTs have a lower reverse leakage current of the gate, and the breakdown voltage is increased by 36%. The current collapse characteristics of the LDD-HEMTs are confirmed by dual-pulse measurement, and an obvious pulse current reduction is due to the surface states by implanting F ions between the gate and the drain.

关键词： High electron mobility transistors

Synthesis of a novel tri-antennary galactoside with high hepatocyte targeting

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Chinese Chemical Letters 2007年第5期18卷 513-515页

作者： Lei Tang Yong Wu Jiao Lu Zhi Rong zhang jin cheng Yang Li Hai Key Laboratory of Drug Targeting Education Ministry West China School of Pharmacy Sichuan University Chengdu 610041 PR China

A novel bifunctional compound carrying duster thiogalactoside as the cell targeting ligands was synthesized for gene delivery to hepatocytes. Tetra-antennary dendr-OMs4 5 was used as a scaffold for the attachment of three galactosides, while the other mesylate end was linked with cholesterol through poly（ethylene glycol） chain. This design provided an effective entry for the synthesis of the bifunctional compound.

关键词： Cluster Cholesterylated galactoside Targeting ligand Hepatocyte-specific delivery Gene delivery

2型糖尿病老年患者血清尿酸水平与糖尿病视网膜病变发生及进展的关系

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川北医学院学报 2024年第4期39卷 528-531页

作者：魏静张金成史亚男张慧芹吴岩河北省沧州市中心医院·河北医科大学沧州临床医学院内分泌一科河北沧州061000 河北省沧州市中心医院·河北医科大学沧州临床医学院眼一科河北沧州061000

目的:探究老年2型糖尿病(T2DM)患者血清尿酸(SUA)水平与糖尿病视网膜病变(DR)发生及进展的关系。方法:回顾性分析300例T2DM患者的临床资料,将其中100例T2DM伴DR且SUA>420μmol/L(高尿酸血症)的患者设为HUDR组;将100例T2DM伴DR且SUA≤420... 详细信息

目的:探究老年2型糖尿病(T2DM)患者血清尿酸(SUA)水平与糖尿病视网膜病变(DR)发生及进展的关系。方法:回顾性分析300例T2DM患者的临床资料,将其中100例T2DM伴DR且SUA>420μmol/L(高尿酸血症)的患者设为HUDR组;将100例T2DM伴DR且SUA≤420μmol/L(无高尿酸血症)的患者设为DR组;将100例T2DM不伴DR患者设为T2DM组,比较各组SUA、血管内皮生长因子(VEGF)、空腹血糖(FBG)、糖化血红蛋白(HbA1c)及超敏C反应蛋白(hs-CRP)水平;比较HUDR组和DR组DR分期构成。Logistic回归分析不同SUA水平对DR发生的影响。结果:各组SUA、VEGF及hs-CRP水平比较:HUDR组>DR组>T2DM组(P221μmol/L时开始对DR的发生有影响,且SUA水平越高,影响程度越大[221μmol/L≤SUA<350μmol/L(OR=2.069,95%CI:1.492~3.559)、350μmol/L≤SUA<438μmol/L(OR=3.270,95%CI:1.908~5.173)、SUA≥438μmol/L(OR=3.802,95%CI:2.163~7.091)]。结论:T2DM伴DR患者SUA水平高于T2DM不伴DR患者,SUA水平升高是DR发生的独立危险因素,也是导致DR进展的重要原因。

关键词： 2型糖尿病老年人血尿酸糖尿病视网膜病变

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Effects of humic acid and surfactants on the aggregation kinetics of manganese dioxide colloids

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Frontiers of Environmental Science & Engineering 2015年第1期9卷 105-111页

作者： Xiaoliu HUANGFU Yaan WANG Yongze LIU Xixin LU Xiang zhang Haijun cheng jin JIANG Jun MA Key Laboratory of Urban Water Resource and Environment School of Municipal and Environmental Engineering Harbin Institute of Technology Harbin 150090 China

The aggregation of common manganese diox- ide （MnO2） colloids has great impact on their surface reactivity and therefore on their fates as well as associated natural and synthetic contaminants in engineered （e.g. water treatment） and natural aquatic environments. Nevertheless, little is known about the aggregation kinetics of MnO2 colloids and the effect of humic acid （HA） and surfactants on these. In this study, the early stage aggregation kinetics of MnO2 nanoparticles in NaNO3 and Ca（NO3）2 solutions in the presence of HA and surfactants （i.e., sodium dodecyl sulfate （SDS）, and polyvinylpyrrolidone （PVP）） were modeled through time-resolved dynamic light scattering. In the presence of HA, MnO2 colloids were significantly stabilized with a critical coagulation concentration （CCC） of-300mmol · L-1 NaNO3 and 4 mmol.L-1 Ca（NO3）2. Electrophoretic mobility （EPM） measurements confirmed that steric hindrance may be primarily responsible for increasing colloidal stability in the presence of HA. Moreover, the molecular and/or chemical properties of HA might impact its stabilizing efficiency. In the case of PVP, only a slight increase of aggregation kinetics was observed, due to steric reactions originating from adsorbed layers of PVP on the MnO2 surface. Consequently, higher CCC values were obtained in the presence of PVP. However, there was a negligible reduction in MnO2 colloidal stability in the presence of 20 mg·L-1SDS.

关键词： manganese dioxide colloids humic acid,surfactant aggregation kinetics drinking water

Synthesis and Bioactivities of Novel N-（4-（2-Aryloxythiazol- 5-yl）but-3-yn-2-yl）benzamides

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Chinese Journal of Chemistry 2013年第2期31卷 173-181页

作者： Youquan Zhu Pei Liu Danyang Wang jin zhang Jie cheng Yuan Ma Xiaomao Zou Huazheng Yang State Key Laboratory of Elemento-organic Chemistry Institute of Elemento-organic Chemistry Nankai University Tianjin 300071 China

A series of novel N-（4-（2-aryloxythiazol-5-yl）but-3-yn-2-yl）benzamide derivatives were designed and synthesized. Their structures were identified by IH NMR and elemental analyses. Preliminary bioassays indicated that some title compounds provided 〉 80% control of Selerotinia selerotiorum at 50 μg/mL and 〉 70% herbicidal activities against B. campestris at 100 μg/mL. Their structure-activities relationships were also discussed.

关键词： fungicides benzamide ACCase aryloxythiazole herbicide