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Recent progress of two-dimensional metal-base catalysts in urea oxidation reaction

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Rare Metals 2024年第8期43卷 3607-3633页

作者： Qi-Xiang Huang Fang Wang Yong Liu Bi-ying zhang Fang-Ya Guo Zhong-Qiu Jia Hao Wang Tian-Xiang Yang Hai-Tao Wu Feng-zhang Ren Ting-Feng Yi School of Materials Science and Engineering Henan University of Science and Technology School of Environmental Engineering and Chemistry Luoyang Institute of Science and Technology Henan Province International Joint Laboratory of Materials for Solar Energy Conversion and Lithium Sodium Based Battery School of Chemistry and Life Sciences Suzhou University of Science and Technology School of Materials Science and Engineering Northeastern University

Urea oxidation reaction(UOR) is an auxiliary water electrolysis hydrogen production technology developed in recent years to replace oxygen evolution reaction and reduce energy consumption,which can produce hydrogen more efficiently by low theoretical potential,reduce the average cost of electrochemical hydrogen production,and is a frontier research hotspot for renewable hydrogen ***-dimensional(2D) nanomaterials as electrocatalysts have many favorable potential,such as it can effectively reduce the resistivity of materials and increase the specific surface area with *** paper reviews the application of 2D materials in UOR in alkaline *** a cross-sectional comparison of various material performance data including overpotential,Tafel slope,electrochemical active surface area(ECSA) and it stability test was conducted,which could illustrate the differences between materials composed of different *** addition,the main challenges hindering the progress of research on 2D materials in urea electrocatalysis processes and promising materials in this field in future are summarized and *** is believed that this review will contribute to designing and analyzing highperformance 2D urea electrocatalysts for water splitting.

关键词： Water splitting Urea oxidation reaction Two-dimensional Transition metal compounds Nobleon-noble metals

Systematical High-Pressure Study of Praseodymium Nitrides in N-Rich Region

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Chinese Physics Letters 2024年第6期41卷 67-87页

作者：刘冉刘爽张盈王鹏姚震 State Key Laboratory of Superhard Materials College of PhysicsJilin UniversityChangchun 130012China

We investigate high-pressure phase diagrams of Pr–N compounds by proposing five stable structures(PnmaPr N,Ⅰ4/mmm-PrN_(2),C2/m-PrN_(3),P■-PrN_(4),and R3-PrN_(8))and two metastable structures(P■-PrN_(6)and P■-PrN_(10)).The P■-PrN_(6)with the N14-ring layer and R3-PrN_(8)with the N18-ring layer can be quenched to ambient *** the P■-PrN_(10),the N_(22)-ring layer structure transfers into infinite chains with the pressure quenched to ambient ***,a novel polynitrogen h R8-N designed by the excision of Pr atoms from R3-PrN_(8)is obtained and can be quenched to ambient *** N-rich structures of P■-PrN_(6),R3-PrN_(8),c-PrN_(10)and the solid pure nitrogen structure exhibit outstanding properties of energy density and explosive performance.

关键词： ambient structure layer

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Celastrol regulates the oligomeric state and chaperone activity of αB-crystallin linked with protein homeostasis in the lens

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Fundamental Research 2024年第2期4卷 394-400页

作者： Huaxia Wang Qing Tian ying zhang Yibo Xi Lidan Hu Ke Yao Jingyuan Li Xiangjun Chen Eye Center of the Second Affiliated Hospital Zhejiang University School of Medicine88 Jiefang RoadHangzhou 310009China Institute of Translational Medicine Zhejiang University School of Medicine268 Kaixuan RoadHangzhou 310020China. State Key Laboratory of Membrane Biology School of Life SciencesTsinghua UniversityBeijing 100084China The Children’s Hospital Zhejiang University School of MedicineNational Clinical Research Center for Child HealthHangzhou 310052China Zhejiang Province Key Laboratory of Quantum Technology and Device Department of PhysicsZhejiang UniversityZheda Road 38Hangzhou 310027China

Protein misfolding and aggregation are crucial pathogenic factors for cataracts,which are the leading cause of visual impairment worldwide.α-crystallin,as a small molecular chaperone,is involved in preventing protein misfolding and maintaining lens *** chaperone activity of α-crystallin depends on its oligomeric *** previous work identified a natural compound,celastrol,which could regulate the oligomeric state of α*** this work,based on the UNcle and SEC analysis,we found that celastrol induced𝛼αB-crystallin to form large *** oligomer formation enhanced the chaperone activity of αB-crystallin and prevented aggregation of the cataract-causing mutant α*** interactions between𝛼αB-crystallin and celastrol were detected by the FRET(Fluorescence Resonance Energy Transfer)technique,and verified by molecular *** least 9 binding patterns were recognized,and some binding sites covered the groove structure of α***,αB-R120G,a cataract-causing mutation located at the groove structure,and celastrol can decrease the aggregates of α***,our results suggested celastrol not only promoted the formation of large αB-crystallin oligomers,which enhanced its chaperone activity,but also bound to the groove structure of its α-crystallin domain to maintain its structural *** might serve as a chemical and pharmacological chaperone for cataract treatment.

关键词： αB-crystallin Celastrol Interactions Oligomeric state Chaperone activity Structural stability

Structural characteristics and tectonic division of the Zambezi Delta basin in the offshore East Africa:evidences from gravity and seismic data

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Acta Oceanologica Sinica 2024年第4期43卷 105-118页

作者： Guozhang Fan Wen Li Liangbo Ding Wanyin Wang Hongping Wang Dingding Wang Lin Li Hao Wang Chaofeng Wang Qingluan Wang ying zhang Hangzhou Research Institute of Petroleum Geology PetroChinaHangzhou 310023China College of Geological Engineering and Geomatics Chang’an universityXi’an 710054China Key Laboratory of Marine Geology and Environment Chinese Academy of SciencesQingdao 266071China National Engineering Research Center of Offshore Oil and Gas Exploration Beijing 100028China Department of Earth Environment and Resources SciencesUniversity of Naples FedericoⅡNaples 80138Italy

The Zambezi Delta basin is a passive marginal basin located on the East African coast that has good oil and gas exploration *** to the special geological evolutionary background of the Beira High in the Zambezi Delta basin,it has a low gravity anomaly,and the existing seismic survey lines do not cover the whole basin;therefore,it is difficult to interpret the structural characteristics of the whole basin based solely on gravity or seismic *** on satellite altimetry gravity anomaly data,this study infers the distribution characteristics of faults in the Zambezi Delta basin by using the normalized vertical derivative of the total horizontal derivative(NVDR-THDR)***,constrained by seismic data,the gravity anomaly at the Moho interface is extracted by using the fast forward method of the double-interface model of the gravity anomaly,and this anomaly is then removed from the Bouguer gravity anomaly to obtain the sedimentary layer gravity *** thickness of the sedimentary strata is obtained by inversing the sedimentary basement depth of the whole ***,uplifts and depressions are divided based on a sedimentary layer thickness of 3 *** research demonstrates that the Zambezi Delta basin mainly features nearly SN-trending and NE-trending faults and that these faults exhibit east-west *** nearly SN-trending strike-slip faults controlled the sedimentary development of the basin,and the NE-trending tensile faults may have acted as migration channels for oil,gas and ***“overcompensation”effect of the Moho interface gravity anomaly on the gravity anomaly of the sedimentary layer is caused by the depression of the Moho interface beneath the Beira High,which results in a low gravity anomaly value for the Beira *** pattern of uplifts and depressions trends NE and has the structural characteristics of east-west blocks.

关键词： Zambezi Delta basin satellite altimetry gravity anomaly Beira High fault division uplift and depression pattern

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Epigenetic silencing schlafen-11 sensitizes esophageal cancer to ATM inhibitor

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World Journal of Gastrointestinal Oncology 2024年第5期16卷 2060-2073页

作者： Jing Zhou Mei-ying zhang Ai-Ai Gao Cheng Zhu Tao He James G Herman Ming-Zhou Guo School of Medicine NanKai UniversityTianjin 300071China Department of Gastroenterology and Hepatology The First Medical CenterChinese PLA General HospitalBeijing 100853China Departments of Pathology Characteristic Medical Center of The Chinese People’s Armed Police ForceTianjin 300162China The Hillman Cancer Center University of Pittsburgh Cancer InstitutePittsburghPA 15213United States National Key Laboratory of Kidney Diseases Chinese PLA General HospitalBeijing 100853China

BACKGROUND Targeting DNA damage response(DDR)pathway is a cutting-edge *** has been reported that Schlafen-11(SLFN11)contributes to increase chemosensitivity by participating in ***,the detailed mechanism is *** To investigate the role of SLFN11 in DDR and the application of synthetic lethal in esophageal cancer with SLFN11 *** To reach the purpose,eight esophageal squamous carcinoma cell lines,142 esophageal dysplasia(ED)and 1007 primary esophageal squamous cell carcinoma(ESCC)samples and various techniques were utilized,including methylationspecific polymerase chain reaction,CRISPR/Cas9 technique,Western blot,colony formation assay,and xenograft mouse *** Methylation of SLFN11 was exhibited in 9.15%of(13/142)ED and 25.62%of primary(258/1007)ESCC cases,and its expression was regulated by promoter region ***11 methylation was significantly associated with tumor differentiation and tumor size(both P<0.05).However,no significant associations were observed between promoter region methylation and age,gender,smoking,alcohol consumption,TNM stage,or lymph node *** DNA damaged model induced by low dose cisplatin,SLFN11 was found to activate non-homologous end-joining and ATR/CHK1 signaling pathways,while inhibiting the ATM/CHK2 signaling *** silencing of SLFN11 was found to sensitize the ESCC cells to ATM inhibitor(AZD0156),both in vitro and in *** SLFN11 is frequently methylated in human *** of SLFN11 is sensitive marker of ATM inhibitor in ESCC.

关键词： Schlafen-11 Esophageal squamous cell carcinoma DNA methylation Synthetic lethality AZD0156

Coupling and Long-term Change Characteristics of Forest Carbon Sink and Forestry Economic Development in China

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Asian Agricultural Research 2024年第7期16卷 1-11页

作者： ying zhang Na MENG Keren zhang School of Economics&Management Beijing Forestry UniversityBeijing 100083China School of Design Hong Kong Polytechnic UniversityHung HomKowloon 999077China

[Objectives]To analyze the changes in of forest carbon sink and forestry economic development,provide reference for relevant management decisions,ecological governance and resource and environment management,and promote the development of green low-carbon economy in China.[Methods]Based on the data of six forest resource inventories from 1989 to 2018 and related studies,the comprehensive evaluation model of forest carbon sink and forestry economic development,the coupling degree model of forest carbon sink and forestry economic development,and the coupling coordination degree model of forest carbon sink and forestry economic development were *** coupling degree of forest carbon sink and forestry economic development from 1992 to 2018 was *** regression and ARIMA model were used to analyze the influencing factors and lagging characteristics of forest carbon *** coupling degree between forest carbon sink and forestry economic development in China from 2019 to 2030 was predicted by autoregression and ADF *** coupling between forest carbon sink and forestry economic development in China and its long-term change characteristics were also discussed in this study.[Results](i)The investment of ecological construction and protection,the actual investment of forestry key ecological projects,GDP and the import of forest products had a significant impact on forest resources carbon *** total output value of forestry industry,the actually completed investment of forestry key ecological projects and the export volume of forest products had a significant impact on the forest carbon sink,and the actually completed investment of forestry key ecological projects has the greatest impact on the two.(ii)The impact of actually completed investment of forestry key ecological projects had a lag of 2 years on the forest resources carbon stock and a lag of 1 year on the forest carbon *** investing in forest carbon sink,it is necessary to make a good

关键词： Forest resources carbon stock Forest carbon sink Coupling coordination degree Forestry economic development Long-term trend

Efficacy of spray flushing in the reprocessing of flexible endoscopes:A randomized controlled trial

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World Journal of Gastroenterology 2024年第31期30卷 3680-3688页

作者： Jiang Du Miao zhang Si-Yuan Tao Lian-Song Ye Hui Gong Bing Hu Qiong-ying zhang Fu Qiao Department of Gastroenterology and Hepatology West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina West China School of Nursing Sichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Infection Control West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Digestive Endoscopy Medical Engineering Research Laboratory West China Hospital of Sichuan UniversityChengdu 610041Sichuan ProvinceChina

BACKGROUND Commonly used cleaning brushes in the reprocessing of flexible endoscopes often cause damage within the working *** To develop a spray flushing system to achieving effective cleaning of the working channels while minimizing *** This prospective study included 60 used endoscopes and 60 Teflon tubes randomly divided into a control group(n=30)and an experimental group(n=30).The material of Teflon tubes was the same as that of the endoscope working *** in the control group were manually cleaned using traditional cleaning brushes,while those in the experimental group were cleaned using the newly developed spray flushing *** levels,cleanliness,and microbiological testing of the working channels were ***,Teflon tubes in the control group underwent 500 passes with a cleaning brush,while those in the experimental group were subjected to the spray flushing system,and channel damage was *** The ATP levels(RLU)in the two groups were 32.5(13-66)and 26(16-40),respectively(P>0.05).Cleanliness scores were 1.5(1-2)and 1(1-2),respectively(P>0.05).Debris was found in 73.3%of the control group,which was significantly higher than 46.7%in the experimental group(P<0.05).Microbiological tests for both groups yielded negative *** tube damage in the control group was rated at 4(4-5.25),which was significantly higher than in the experimental group 4(3-4)(P<0.01).CONCLUSION The spray flushing system demonstrated superior efficacy in removing debris and resulted in less damage to the endoscope working channels compared with traditional cleaning brushes.

关键词： Endoscope ATP Flexible endoscope Disinfection Reprocessing

NF-κB/NLRP3信号通路在急性睡眠剥夺致小鼠焦虑抑郁样行为中的调控作用

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现代预防医学 2024年第10期51卷 1852-1859+1871页

作者：潘芸王洁张文平张英英山西医科大学公共卫生学院流行病学教研室煤炭环境致病与防治教育部重点实验室

目的探讨NF-κB/NLRP3信号通路在急性睡眠剥夺致小鼠焦虑抑郁样行为中的调控作用。方法选取48只8周龄雄性C57BL/6J小鼠，随机分为4组：对照组(CON)、抑制剂组(lithium chlo-ride, LiCl)、睡眠剥夺组(sleep deprivation, SD)和睡眠剥夺... 详细信息

目的探讨NF-κB/NLRP3信号通路在急性睡眠剥夺致小鼠焦虑抑郁样行为中的调控作用。方法选取48只8周龄雄性C57BL/6J小鼠，随机分为4组：对照组(CON)、抑制剂组(lithium chlo-ride, LiCl)、睡眠剥夺组(sleep deprivation, SD)和睡眠剥夺+抑制剂组(SD+LiCl),每组12只。采用多平台水环境改良法(modified multiple platform method, MMPM)构建小鼠急性睡眠剥夺模型，利用高架十字迷宫实验、旷场实验、悬尾实验和强迫游泳实验评估小鼠焦虑抑郁样行为学改变，HE染色观察小鼠海马组织病理学改变，RT-PCR法检测小鼠核因子κB(Nuclear factor kappa B,NF-κB)、核苷酸结合寡聚化结构域样受体热蛋白结构域相关蛋白3(NOD-like receptor thermal protein domain associated protein3,NLRP3)的mRNA表达。结果与CON组相比，SD组小鼠体重、海马重量、海马脏器系数均显著降低(F=0.452,P=0.006;F=6.553,P=0.009;F=1.428,P=0.001)。在旷场实验中，与CON组相比，LiCl组进入中心区域次数无统计学差异(F=5.084,P=0.744),SD组显著减少(F=0.028,P=0.017)。在高架十字迷宫实验中，与CON组相比，LiCl组进入开放臂时间无统计学意义(F=0.09,P=0.113),SD组显著减少(F=0.085,P=0.011)。强迫游泳实验结果显示，与CON组相比，LiCl组小鼠不动时间无统计学差异(F=3.422,P=0.260)。悬尾实验表明，与CON组相比，SD组悬尾不动时间显著增加(F=11.218,P=0.005)。HE染色结果显示，与CON组相比，SD组以及SD+LiCl组小鼠海马组织均出现显著病理学改变。RT-PCR结果表明，与CON组相比，LiCl组NF-κB和NLRP3的mRNA表达无统计学差异(F=4.629,P=0.147;F=15.555,P=0.107),而SD组均显著增高(F=6.969,P<0.001;F=15.833,P=0.017)。结论 NF-κB/NLRP3通路可能在SD致小鼠焦虑抑郁样行为的发生过程中发挥调控作用。

关键词：急性睡眠剥夺焦虑样行为抑郁样行为 NF-κB/NLRP3通路氯化锂

On the relationship between imprint and reliability in Hf_(0.5)Zr_(0.5)O_(2) based ferroelectric random access memory

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Journal of Semiconductors 2024年第4期45卷 42-47页

作者： Peng Yuan Yuting Chen Liguo Chai Zhengying Jiao Qingjie Luan Yongqing Shen ying zhang Jibin Leng Xueli Ma Jinjuan Xiang Guilei Wang Chao Zhao Beijing Superstring Academy of Memory Technology Beijing 100176China

The detrimental effect of imprint,which can cause misreading problem,has hindered the application of ferroelectric HfO_(2).In this work,we present results of a comprehensive reliability evaluation of Hf_(0.5)Zr_(0.5)O_(2)-based ferroelectric random access *** influence of imprint on the retention and endurance is ***,a solution in circuity is pro-posed to effectively solve the misreading problem caused by imprint.

关键词： FeRAM HZO imprint reliability

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