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Multi-performance evaluation of high-throughput accelerated corrosion test for high-strength low-alloy 921A steel

Journal of Iron and Steel Research International 2024年第5期31卷 1260-1278页

作者： Cong-cong Du Ming-hua Qin zhan-fang wu Dong-ling Li Lei Zhao Xiang-yang Li Hai-zhou Wang Beijing Advanced Innovation Center for Materials Genome Engineering National Center for Materials Service SafetyUniversity of Science and Technology BeijingBeijing100083China China Iron and Steel Research Institute Group Co. Ltd.Beijing100081China Beijing Advanced Innovation Center for Materials Genome Engineering Central Iron and Steel Research InstituteBeijing100081China

The corrosion behavior of high-strength low-alloy 921A steel in a simulated marine atmospheric environment was studied using a high-throughput experimental *** corrosion behavior,corrosion morphology,and corrosion products of 921A steels were analyzed using various techniques,including corrosion mass loss method,polarization curve,white-light interferometry,scanning electron microscopy,energy-dispersive spectrometry,microbeam X-ray fluorescence spectrometry,X-ray diffraction technique,and X-ray photoelectron *** test results indicated that 921A steel exhibits better corrosion resistance than Q450NQR1 steel in simulated harsh atmospheric environments,as evidenced by a lower corrosion mass loss rate throughout the corrosion *** corrosion products of both steels consisted ofα-FeOOH,Fe_(3)O_(4),andγ-FeOOH,withα-FeOOH being more prevalent in the rust layer of 921A steel than in Q450NQR1 *** inner rust layer of 921A steel also exhibited an appositional enrichment region of Cr,Ni,Mo,and V,leading to its superior corrosion resistance compared to that of Q450NQR1 *** efficacy of high-throughput accelerated corrosion experimental methods was highlighted for evaluating the corrosion resistance of steel materials in harsh environmental *** findings suggest that 921A steel exhibits better corrosion resistance compared to Q450NQR1 steel and has the potential to be more suitable in harsh marine atmospheric *** characterization of the rust layer structures and composition reveals the parallel enrichment of certain elements in the inner rust layer of 921A steel,which enhances its corrosion resistance.

关键词： Atmospheric corrosion High-throughput experimental method High-strength low-alloy steel Corrosion characteristics Rust layer Element enrichment

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从众心理影响下的行人群体行为演化博弈的仿真分析——以行人过街为例

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吉林大学学报（工学版） 2017年第1期47卷 92-96页

作者：吴文静王占中马芳武吉林大学交通学院长春130022 吉林大学汽车学院长春130022

以行人过街为例对从众效应进行研究,提出了从众效应的量化策略。构建了从众心理影响下的行人过街的演化博弈模型。将行人划分为冒险、折中、保守三类,设计了行人群体行为演化的仿真实验。结果表明:群体构成以及违章过街群体占总人群比... 详细信息

以行人过街为例对从众效应进行研究,提出了从众效应的量化策略。构建了从众心理影响下的行人过街的演化博弈模型。将行人划分为冒险、折中、保守三类,设计了行人群体行为演化的仿真实验。结果表明:群体构成以及违章过街群体占总人群比例对群体行为演化影响显著。最后提出了考虑从众效应的行人社会力仿真模型的改进策略。本文的研究方法扩展了行人行为研究的分析手段,研究结果可为行人仿真模型参数的设置提供参考。

关键词：交通运输系统工程从众效应行人过街演化博弈

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Single-cell transcriptomic profiling reveals ZEB1-mediated regulation in microglial subtypes and the impact of exercise on neuroinflammatory responses

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Traditional Medicine Research 2025年第2期10卷 55-64页

作者： Jin-fang wu Yi-Sheng Chen Yu-Chun Xie Department of Rehabilitation Medicine Jiangsu Province Geriatric HospitalNanjing 210024China Fujian Key Laboratory of Toxicant and Drug Toxicology Medical CollegeNingde Normal UniversityNingde 352100China Central Laboratory Jiangsu Province Geriatric HospitalNanjing 210024China

Background:This study aims to identify distinct cellular subtypes within brain tissue using single-cell transcriptomic analysis,focusing on specific biomarkers that differentiate cell types and the effects of traditional and exercise ***:Four samples were analyzed:older control(OC),older exercise(OE),younger control(YC),and younger exercise(YE).Single-cell RNA sequencing was used to distinguish cellular subtypes through their biomarker *** visualization included violin and t-SNE plots to illustrate biomarker expression across cell clusters such as oligodendrocytes,microglia,and ***,BV2 cells were exposed to amyloid-beta fragments to simulate Alzheimer’s disease,assessing the impact of exercise-induced cellular ***:Distinct cellular subtypes were identified:oligodendrocytes(MBP,St18),microglia(Dock8),and astrocytes(Aqp4,Gpc5).Sample OE was predominantly oligodendrocytes,while YE had more astrocytes,inhibitory neurons,and Canal-Retzius *** showed a significant presence of Olfm3+ganglion ***1 gene knockout revealed changes in SMAD family gene expression,which regulate *** stress levels were also ***:This profiling enhances our understanding of brain cellular functions and interactions,potentially informing targeted therapies in neurological *** may influence brain cell immune responses and cell death pathways by regulating specific gene expressions,offering new insights for treating neuroinflammation and degeneration.

关键词： single-cell transcriptomics brain tissue cellular subtypes biomarker expression neuronal diversity

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Highly mass activity electrocatalysts with ultralow Pt loading on carbon black for hydrogen evolution reaction

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 182-190页

作者： Shaorou Ke Yajing Zhao Xin Min Yanghong Li Ruiyu Mi Yangai Liu Xiaowen wu Minghao fang Zhaohui Huang Engineering Research Center of Ministry of Education for Geological Carbon Storage and Low Carbon Utilization of Resources Beijing Key Laboratory of Materials Utilization of Nonmetallic Minerals and Solid WastersNational Laboratory of Mineral MaterialsSchool of Materials Science and TechnologyChina University of Geosciences(Beijing)Beijing 100083China

Pt-based nanocatalysts offer excellent prospects for various ***,the low loading of Pt with excellent performance for efficient and stable nanocatalysts still presents a considerable *** this study,nanocatalysts with ultralow Pt content,excellent performance,and carbon black as support were prepared through in-situ ***~2-nm particles uniformly and stably dispersed on carbon black because of the strong s-p-d orbital hybridizations between carbon black and Pt,which suppressed the agglomeration of Pt *** unique structure is beneficial for the hydrogen evolution *** catalysts exhibited remarkable catalytic activity for hydrogen evolution reaction,exhibiting a potential of 100 mV at 100 mA·cm^(-2),which is comparable to those of commercial Pt/C *** activity(1.61 A/mg)was four times that of a commercial Pt/C catalyst(0.37 A/mg).The ultralow Pt loading(6.84wt%)paves the way for the development of next-generation electrocatalysts.

关键词： hydrogen evolution reaction ultralow platinum in-situ synthesis ultrasound

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Inhibiting ceramide synthase 5 expression in microglia decreases neuroinflammation after spinal cord injury

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Neural Regeneration Research 2025年第10期20卷 2955-2968页

作者： Wei zhang Yubao Lu Ruoqi Shen Yingjie wu Chenrui Liu Xingxing fang Liangming zhang Bin Liu Limin Rong Department of Spine Surgery The Third Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina National Medical Products Administration(NMPA)Key Laboratory for Quality Research and Evaluation of Cell Products GuangzhouGuangdong ProvinceChina Guangdong Provincial Center for Quality Control of Minimally Invasive Spine Surgery GuangzhouGuangdong ProvinceChina Guangdong Provincial Center for Engineering and Technology Research of Minimally Invasive Spine Surgery GuangzhouGuangdong ProvinceChina

Microglia,the resident monocyte of the central nervous system,play a crucial role in the response to spinal cord ***,the precise mechanism remains *** investigate the molecular mechanisms by which microglia regulate the neuroinflammatory response to spinal cord injury,we performed single-cell RNA sequencing dataset analysis,focusing on changes in microglial *** found that the MG1 subpopulation emerged in the acute/subacute phase of spinal cord injury and expressed genes related to cell pyroptosis,sphingomyelin metabolism,and neuroinflammation at high ***,we established a mouse model of contusive injury and performed intrathecal injection of siRNA and molecular inhibitors to validate the role of ceramide synthase 5 in the neuroinflammatory responses and pyroptosis after spinal cord ***,we established a PC12-BV2 cell co-culture system and found that ceramide synthase 5 and pyroptosis-associated proteins were highly expressed to induce the apoptosis of neuron *** ceramide synthase 5 expression in a mouse model of spinal cord injury effectively reduced ***,ceramide synthase 5-induced pyroptosis was dependent on activation of the NLRP3 signaling *** ceramide synthase 5 expression in microglia in vivo reduced neuronal apoptosis and promoted recovery of neurological ***2g7 formed a“bridge”between sphingolipid metabolism and ceramide synthase 5-mediated cell death by inhibiting the NLRP3 signaling ***,these findings suggest that inhibiting ceramide synthase 5 expression in microglia after spinal cord injury effectively suppressed microglial pyroptosis mediated by NLRP3,thereby exerting neuroprotective effects.

关键词： ceramide synthase 5 gasdermin D microglia neuroinflammation NLRP3 nuclear factor kappa B Pla2g7 pyroptosis sphingomyelin metabolism spinal cord injury

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Recent advances in statistical methodologies in evaluating program for high-dimensional data

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Applied Mathematics(A Journal of Chinese Universities) 2022年第1期37卷 131-146页

作者： zhan Ming-feng CAI Zong-wu fang Ying LIN Ming Wang Yanan Institute for Studies in Economics and Fujian Key Laboratory of Statistical Sciences Xiamen UniversityXiamen 361005China Department of Economics University of KansasLawrenceKS 66045USA Department of Statistics and Data Science Xiamen UniversityXiamen 361005China

The era of big data brings opportunities and challenges to developing new statistical methods and models to evaluate social programs or economic policies or interventions. This paper provides a comprehensive review on some recent advances in statistical methodologies and models to evaluate programs with high-dimensional data. In particular, four kinds of methods for making valid statistical inferences for treatment effects in high dimensions are addressed. The first one is the so-called doubly robust type estimation, which models the outcome regression and propensity score functions simultaneously. The second one is the covariate balance method to construct the treatment effect estimators. The third one is the sufficient dimension reduction approach for causal inferences. The last one is the machine learning procedure directly or indirectly to make statistical inferences to treatment effect. In such a way, some of these methods and models are closely related to the de-biased Lasso type methods for the regression model with high dimensions in the statistical literature. Finally, some future research topics are also discussed.

关键词： causal inference covariate balance de-biased Lasso dimension reduction doubly robust high dimensions machine learning treatment effect

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Cyber-attack Detection Strategy Based on Distribution System State Estimation

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Journal of Modern Power Systems and Clean Energy 2020年第4期8卷 669-678页

作者： Huan Long Zhi wu Chen fang Wei Gu Xinchi Wei Huiyu zhan IEEE School of Electrical Engineering Southeast UniversityNanjingChina State Grid Shanghai Electric Power Company Electric Power Research InstituteShanghaiChina China Electric Power Research Institute BeijingChina

Cyber-attacks that tamper with measurement information threaten the security of state estimation for the current distribution *** paper proposes a cyber-attack detection strategy based on distribution system state estimation(DSSE).The uncertainty of the distribution network is represented by the interval of each state variable.A three-phase interval DSSE model is proposed to construct the interval of each state *** improved iterative algorithm(IIA)is developed to solve the interval DSSE model and to obtain the lower and upper bounds of the interval.A cyber-attack is detected when the value of the state variable estimated by the traditional DSSE is out of the corresponding interval determined by the interval *** validate the proposed cyber-attack detection strategy,the basic principle of the cyber-attack is studied,and its general model is *** proposed cyber-attack model and detection strategy are conducted on the IEEE 33-bus and 123-bus *** experiments of the proposed IIA,Monte Carlo simulation algorithm,and interval Gauss elimination algorithm prove the validation of the proposed method.

关键词： Cyber-attack detection distribution network interval state estimation distribution system state estimation cyber-attack model

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Back Frame Optimization of a Large Radio Telescope Based on Force Cone Method

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wuhan University Journal of Natural Sciences 2022年第5期27卷 424-438页

作者： wu Qinglong YAO zhan wu Tanhui fang Houfei HOU Yangqing Shanghai YueSheng Information Technology Co. Shanghai 201108China

A new research perspective is proposed to optimize the topology of truss structure by force cone method,which involves force cone drawing rules and growth *** the comparison with the mature variable density topology optimization method,the effectiveness of force cone method is *** kind of new method is simple and easy to understand(no need to master complex structural optimization design theory).Besides,it is time-saving in finite element calculations,and can obtain an optimized truss layout *** drawing the force cone,its application on a large radio telescope’s back frame structure shows that,compared with the existing one in terms of structural stiffness,Root Mean Square(RMS)precision,and beam stress distribution,the optimized back frame using the force cone method has higher stiffness,better RMS,more uniform stress,and lighter weight.

关键词： large radio telescope back frame force cone method topology optimization

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Comparison of Covariate Balance Weighting Methods in Estimating Treatment Effects

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Journal of Systems Science & Complexity 2022年第6期35卷 2263-2277页

作者： zhan Mingfeng fang Ying LIN Ming Wang Yanan Institute for Studies in Economics and Fujian Key Laboratory of Statistical Sciences Xiamen UniversityXiamen 361005China Department of Statistics and Data Science Xiamen UniversityXiamen 361005China

Different covariate balance weighting methods have been proposed by researchers from different perspectives to estimate the treatment *** paper gives a brief review of the covariate balancing propensity score method by Imai and Ratkovic(2014),the stable balance weighting procedure by Zubizarreta(2015),the calibration balance weighting approach by Chan,et al.(2016),and the integrated propensity score technique by Sant’Anna,et al.(2020).Simulations are conducted to illustrate the finite sample performance of both the average treatment effect and quantile treatment effect estimators based on different weighting *** results show that in general,the covariate balance weighting methods can outperform the conventional maximum likelihood estimation method while the performance of the four covariate balance weighting methods varies with the data generating ***,the four covariate balance weighting methods are applied to estimate the treatment effects of the college graduate on personal annual income.

关键词： Average treatment effect calibration balance weighting covariate balance integrated propensity score quantile treatment effects stable balance weighting

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Anomalous Dissipative Quantum Harmonic Oscillator

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Communications in Theoretical Physics 2008年第1期49卷 137-142页

作者： BAI zhan-wu Department of Mathematics and Physics North China Electric Power University Baoding 071003 China

We investigate the low-temperature statistical properties of a harmonic oscillator coupled to a heat bath, where the low-frequency spectrum vanishes. We obtain the exact result of the zero point energy. Due to the low frequency shortage of environmental oscillators＇ spectral density, the coordinate and momentum correlation functions decay as T^-4 arid T^-6 respectively at zero temperature, where T is the correlation time. The low-temperature behavior of the mean energy does not violate the third law of thermodynamics, but differs largely from the Ohmic spectrum case.

关键词： harmonic oscillator harmonic velocity noise zero point energy correlation function the thirdlaw of thermodynamics

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