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Hepatobiliary & Pancreatic Diseases International 2025年第1期24卷 104-107页

作者： Bei Lu Jun-jie Yin Jing-Rui wang Xiao Xu Yang Cai Department of Hepato-Pancreato-Biliary Surgery Affiliated Hangzhou First People’s HospitalWestlake University School of MedicineHangzhou 310006China

Acute necrotizing pancreatitis(ANP)is a critical type of acute pancreatitis(AP)[1,2].ANP has high mortality,long-term hospitalization,high cost,and potential morbidity[3,4].Infected or symptomatic necrosis continually requires debridement as the mainstay of treatment when percutaneous drainage fails[5].With the advent of minimally invasive approaches in recent decades,surgical management of pancreatic necrosis has been *** recommend using a step-up approach instead of direct open pancreatic necrosectomy(OPN)[6].Endoscopic drainage and necrosectomy are appropriate for walled-offnecrosis(WON)near the stomach or duodenum[7].Minimal access retroperitoneal pancreatic necrosectomy(MARPN)is a good approach for laterally located WON that is distant from the stomach or duodenum[8].However,these minimally invasive approaches are still not *** repeatedly debridement itself causes ***,large pieces of necrosis are not easy to clear,and blood vessels are difficult to *** of bleeding,gastrointestinal fistula,and pancreatic fistula are still inevitable.

关键词： stomach debridement Acute

Gut-brain axis as a bridge in obesity and depression:Mechanistic exploration and therapeutic prospects

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World Journal of Psychiatry 2025年第1期15卷 12-20页

作者： Rui-Ying Fang Xiao-Rui Pan Xin-Xing zeng Zheng-Zheng Li Bo-Fan Chen Hai-Min zeng jie Peng The Second Clinical Medical College The Second Affiliated HospitalJiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina

A recent study by wang et al,published in the World Journal of Psychiatry,provided preventative and therapeutic strategies for the comorbidity of obesity and *** gut-brain axis,which acts as a two-way communication system between the gastrointestinal tract and the central nervous system,plays a pivotal role in the pathogenesis of these *** suggests that metabolic byproducts,such as short-chain fatty acids,lipopolysaccharide and bile acids,which are generated by the gut microbiota,along with neurotransmitters and inflammatory mediators within the gut-brain axis,modulate the host's metabolic processes,neuronal regulation,and immune responses through diverse *** interaction between obesity and depression via the gut-brain axis involves disruptions in the gut microbiota balance,inflammatory immune responses,and alterations in the neuroendocrine *** the gut-brain axis,for example,through a ketogenic diet,the use of probiotics,and the supplementation of antioxidants,offers new remedial approaches for obesity and *** research that explores the mechanisms of the gut-brain axis is needed to provide more evidence for clinical treatment.

关键词： Gut-brain axis Obesity Depression Gut microbiota Mechanism

Goat casein hydrolysates alleviated insomnia in mice via modulating the level of neurotransmitters and the composition of gut microbiota

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Food Science and Human Wellness 2025年第1期14卷 212-225页

作者： Ling Mo Huijuan Jing Xiaojing Du Chaochao Zhao Yintao Lin jie Li Hongxin wang State Key Laboratory of Food Science and Technology Jiangnan UniversityWuxi 214122China School of Food Science and Technology Jiangnan UniversityWuxi 214122China School of Public Health Guilin Medical UniversityGuilin 541199China Sweet Inn(Guangzhou)Technology Development Co. Ltd.Guangzhou 510075China

Insomnia is associated with neurotransmitters and intestinal *** studies have demonstrated the ameliorative effects of milk hydrolysates on insomnia,the underlying mechanisms require further *** this study,we investigated how papain hydrolysates of goat casein(CPH)and whey protein(WPH)affected mice's ***,we show that CPH effectively improved the total sleep time in 12 h and restoring neurotransmitters(5-hydroxytryptamine(5-HT),γ-aminobutyric acid(GABA),dopamine(DA),and norepinephrine(NE))in *** gut microbiota analysis revealed a significant increase in the relative abundance of Helicobacter and Escherichia-Shigella and a decrease in the relative abundance of Lactobacillus in the insomnia model mice(Model).Compared to the Model group,both CPH and WPH significantly increased the relative abundance of Akkermansia and Lactobacillus while lowering the relative abundance of Helicobacter and ***,while diazepam(DZP)increased mouse sleep duration,it also increased the relative abundance of Colidextribacter,Parasutterella,Muribaculaceae,and ***,the gene expression and protein expression of GABA_A receptor,cAMP-response element binding protein(CREB),and brain-derived neurotrophic factor(BDNF)were upregulated in the *** also discovered a link between intestinal gut microbiota and ***,our results suggest that goat milk hydrolysates,especially CPH,can effectively improve insomnia,providing a theoretical basis for further experimentation and individualized designs.

关键词： Goat casein Hydrolysates Insomnia Gut microbiota

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Impact of land use change on carbon storage in the middle reaches of the Yellow River,China

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Journal of Arid Land 2025年第2期17卷 167-181页

作者： SHI Xiaoliang ZHANG jie LIU Simin DING Hao CHEN Xi wang Li ZHANG Dan College of Geomatics Xi'an University of Science and TechnologyXi'an 710054China China National Forestry-Grassland Development Research Center Beijing 100714China

The implementation of long-term shelterbelt programs in the middle reaches of the Yellow River(MRYR),China not only has improved the overall ecological environment,but also has led to the changes of land use pattern,causing carbon storage ***,the relationship between carbon storage and land use change in the MRYR is not concerned,which results in the uncertainty in the simulation of carbon storage in this *** use changes directly affect the carbon storage capacity of ecosystems,and as an indicator reflecting the overall state of land use,land use degree has an important relationship with carbon *** this study,land use data and the integrated valuation of ecosystem services and trade-offs(InVEST)model were used to assess the trends in land use degree and carbon storage in the MRYR during *** potential impact index and the standard deviation ellipse(SDE)algorithm were applied to quantify and analyze the characteristics of the impact of land use changes on carbon ***,land use transitions that led to carbon storage variations and their spatial variations were *** results showed that:(1)the most significant periods of carbon storage changes and land use transitions were observed during 1990-1995 and 1995-2020,with the most changed areas locating in the east of Fenhe River and in northwestern Henan Province;(2)the positive impact of land use degree on carbon storage may be related to the environmental protection measures implemented along the Yellow River,while the negative impact may be associated with the expansion of construction land in plain areas;and(3)the conversion of other land use types to grassland was the primary factor affecting carbon storage changes during *** future land use planning,attention should be given to the direction of grassland conversion,and focus on reasonably limiting the development of construction *** enhance carbon storage,it will be crucial to increase the area

关键词： carbon storage land use degree integrated valuation of ecosystem services and trade-offs(InVEST)model potential impact standard deviation ellipse(SDE)

Methods and mechanisms for enhancing the water retention properties of Jiuzhaigou disintegrated rubble soils

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Journal of Mountain Science 2025年第2期22卷 729-746页

作者： WEI Zeming XI Hongchao PEI Xiangjun ZHANG Xiaochao QIU Mao HUANG Tiao wang Zhaocheng JIANG Junlian DU jie JIAN Daijun State Key Laboratory of Geohazard Prevention and Geoenvironment Protection Chengdu University of TechnologyChengdu 610059China Tianfu Yongxing Laboratory Research Center for Carbon Sequestration and Ecological Restoration Chengdu 610213China Jiuzhaigou Administration Aba 623400China

Rubble deposits with a high concentration of rock debris were created after the powerful earthquakes in *** of the restricted soil resources,water leaks,and nutrient deficits,these deposits pose serious obstacles for vegetation *** purpose of this study was to investigate the main mechanisms controlling soil water retention and evaluate the effects of different amendments on the hydraulic characteristics and water-holding capacity of collapsed rubble *** soil,forest humus,crushed straw,and organic components that retain water were added to the altered soils to study the pore structure images and soil-water characteristic *** understory humus to other supplements,the results showed a considerable increase in the soil's saturated and wilting water *** saturated water content and wilting water content rose by 17.9%and 4.3%,respectively,when the percentage of understory soil reached 30%.Additionally,the enhanced soil's microporosity and total pore volume increased by 45.33%and 11.27%,respectively,according to nuclear magnetic *** was shown that while clay particles and organic matter improved the soil's ability to adsorb water,they also increased the soil's total capacity to store *** particulate matter did this by decreasing macropores and increasing capillary *** results offer an essential starting point for creating strategies for soil repair that would encourage the restoration of plants on slopes that have been damaged.

关键词： Pile-ups Amendments Crumbling rubble soils Water holding capacity Soil-water characteristic curves

As-cast Ti_(x)(AlVCr)_(100−x)light-weight medium entropy alloys with high strength and uniform compressive plasticity

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Transactions of Nonferrous Metals Society of China 2025年第1期35卷 194-206页

作者： Ming-jie KAI Yu-jie MA Xiao-tian wang Liang CHENG Jian-bo HU Yao-yao HU Tai-ran XU Gui-jiang LI Xiang-kang MENG Zhen-hua CAO College of Materials Science and Engineering Nanjing Tech UniversityNanjing 210009China School of Intelligent Manufacturing and Information Jiangsu Shipping CollegeNantong 226010China Laboratory for Shock Wave and Detonation Physics Institute of Fluid PhysicsChina Academy of Engineering PhysicsMianyang 621900China National Laboratory of Solid State Microstructures College of Engineering and Applied SciencesNanjing UniversityNanjing 210093China

The effect of Ti content on the microstructure and mechanical properties of as-cast light-weight Ti_(x)(AlVCr)_(100−x)medium entropy alloys was studied by compressive tests,X-ray diffraction,scanning electron microscopy and transmission electron *** results suggest that yield strength increases and then decreases with the increment of Ti *** Ti_(60)(AlVCr)_(40)alloy has the best combination of high strength of 1204 MPa and uniform plastic strain of 70%,possessing a high specific yield strength of 255 MPa·cm^(3)/*** enhancement of strength is mainly attributed to the synergic effects of solid-solution and coherent nano-precipitation strengthening,while dislocation motion such as dislocation pinning,entanglement and dislocation cells significantly increases the strain-hardening capacity.

关键词： TiAlVCr medium entropy alloy solid solution strengthening b2 precipitate strain hardening behavior

Optical transmittance and pulse shape discrimination of polystyrene/poly(methyl methacrylate)-based plastic scintillators

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Nuclear Science and Techniques 2025年第1期36卷 94-102页

作者： Yi-Yao Liang Ying-Du Liu Pu-Sen wang jie Bao Xiao-Ping Ouyang School of Materials Science and Engineering Xiangtan UniversityXiangtan 411105China Nuclear Data Key Laboratory China Institute of Atomic EnergyBeijing 102413China

Polymethyl methacrylate(PMMA)is an optically transparent thermoplastic with favorable processing *** this study,a series of plastic scintillators are prepared via thermal polymerization,and the impact of PMMA content on their transparency and pulse shape discrimination(PSD)ability is *** fabricated samples,comprising a polystyrene(PS)-PMMA matrix,30.0 wt%2,5-diphenyloxazole(PPO),and 0.2 wt%9,10-diphenylanthracene(DPA),exhibit high transparency with transmissivity ranging from 70.0 to 90.0%(above 415.0 nm)and demonstrate excellent n/γdiscrimination *** increased with increasing PMMA content across the entire visible light ***,the PSD performance gradually deteriorated when the aromatic matrix was replaced with *** scintillator containing 20.0 wt%PMMA demonstrated the best stability concerning PSD properties and relative light yields.

关键词： Neutron detection Plastic scintillation Pulse shape discrimination Polymethyl-methacrylate Polystyrene

A comparison of the proto-dolomite induced by cyanobacteria and halophilic bacteria:implications for dolomite-inducing microbe identification

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Journal of Palaeogeography 2025年第01期14卷 277-290页

作者：赵延洋 Xiang-Yu Wei Xiao Gao Na Guo jie Li Kai-Ming Hu Chao Han Qi-Yu wang 韩作振 Shandong Provincial Key Laboratory of Depositional Mineralization and Sedimentary Minerals College of Earth Science and Engineering Shandong University of Science and Technology Laboratory for Marine Mineral Resources Qingdao National Laboratory for Marine Science and Technology Key Laboratory of Sedimentary Basin and Oil and Gas Resources Ministry of Natural Resources Key Laboratory of Deep Oil and Gas China University of Petroleum

This study investigates the morphological and mineralogical characteristics of proto-dolomite induced by two specific microorganisms with varying lifestyles:the extremely halophilic bacterium Vibrio harveyi QPL2 and the cyanobacterium Leptolyngbya boryana. Halophilic bacterially-induced proto-dolomite(HBD) and cyanobacterially-induced proto-dolomite (CBD) were subjected to comprehensive characterization techniques, including X-ray diffraction, scanning electron microscopy, Focused Ion Beam, thermogravimetric analysis, and X-ray photoelectron spectroscopy. The results indicate that both HBD and CBD exhibit a low degree of crystallinity and possess comparable molar ratios of MgCO3to CaCO3. Moreover, neither of them exhibits the ordered structure of ideal dolomite. HBD and CBD exhibit notable distinctions in external morphology and internal structure. HBD forms a subunit aggregate with a less dense surface and numerous pinhole structures resulting from bacterial survival. In contrast, CBD adopts a bispherical shape with a relatively dense surface and minimal indications of cyanobacterial survival. Both HBD and CBD have an internal hollow structure. However, HBD is characterized by sparse population and loosely arranged subunits, while CBD features only a central cavity. Additionally, HBD particles are smaller compared to CBD particles. These morphological differences suggest that HBD primarily grows through bacterial surface-dependent processes,whereas the growth of CBD is not directly reliant on the surface of cyanobacteria. Compositionally, the weightpercentage of crystalline water in CBD exceeded that of HBD with a value of 29.42%compared to 5.9%. This increase in internal crystalline water enables a faster conversion of CBD to the ordered ideal dolomite in a specific diagenetic environment. This study implies that the morphology and composition of microbial protodolomite may aid in identifying the type of dolomite-inducing microbes.

关键词： Proto-dolomite Cyanobacteria Halophile Crystal morphology Water of crystallization

基于自适应速度控制器的SPMSM弱磁调速研究

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电源世界 2017年第9期 21-26页

作者：谢涛高桂革曾宪文王杰上海电机学院电气学院上海201306 上海电机学院电子信息学院上海201306

为解决引入弱磁算法时传统PI速度控制无法满足系统对负载变化的快速响应,以及超调量、失速等速度跟踪精度问题,在矢量控制算法的基础上研究SPMSM的弱磁控制策略,并设计一种新的自适应速度控制器。本文在MATLAB-Simulink实验仿真平台上,... 详细信息

为解决引入弱磁算法时传统PI速度控制无法满足系统对负载变化的快速响应,以及超调量、失速等速度跟踪精度问题,在矢量控制算法的基础上研究SPMSM的弱磁控制策略,并设计一种新的自适应速度控制器。本文在MATLAB-Simulink实验仿真平台上,对额定转速500r/min和额定转速2000r/min的两种不同弱磁工况的电机进行仿真,验证本文所设计的速度控制器提升弱磁升速系统性能,结果证明具备良好的抗负载扰动能力。

关键词：表贴式永磁同步电机弱磁控制速度控制器跟踪精度

Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke

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Neural Regeneration Research 2025年第3期20卷 845-857页

作者： Lin-Yan Huang Yi-De Zhang jie Chen Hai-Di Fan Wan wang Bin wang Ju-Yun Ma Peng-Peng Li Hai-Wei Pu Xin-Yian Guo Jian-Gang Shen Su-Hua Qi School of Medical Technology Xuzhou Key Laboratory of Laboratory DiagnosticsXuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Pharmacy Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina Department of Laboratory Medicine Branch Hospital of Huai’an First People’s HospitalHuai’anJiangsu ProvinceChina Department of Laboratory Medicine the Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Chinese Medicine The University of Hong KongHong Kong Special Administrative RegionChina

It has been shown clinically that continuous removal of ischemia/reperfusion-induced reactive oxygen species is not conducive to the recovery of late ***,previous studies have shown that excessive increases in hypochlorous acid after stroke can cause severe damage to brain *** previous studies have found that a small amount of hypochlorous acid still exists in the later stage of stroke,but its specific role and mechanism are currently *** simulate stroke in vivo,a middle cerebral artery occlusion rat model was established,with an oxygen-glucose deprivation/reoxygenation model established in vitro to mimic *** found that in the early stage(within 24 hours)of ischemic stroke,neutrophils produced a large amount of hypochlorous acid,while in the recovery phase(10 days after stroke),microglia were activated and produced a small amount of hypochlorous ***,in acute stroke in rats,hypochlorous acid production was prevented using a hypochlorous acid scavenger,taurine,or myeloperoxidase inhibitor,4-aminobenzoic acid *** results showed that high levels of hypochlorous acid(200μM)induced neuronal apoptosis after oxygen/glucose deprivation/***,in the recovery phase of the middle cerebral artery occlusion model,a moderate level of hypochlorous acid promoted the proliferation and differentiation of neural stem cells into neurons and *** suggests that hypochlorous acid plays different roles at different phases of cerebral ischemia/reperfusion *** levels of hypochlorous acid(5 and 100μM)promoted nuclear translocation ofβ-*** transfection of single-site mutation plasmids,we found that hypochlorous acid induced chlorination of theβ-catenin tyrosine 30 residue,which promoted nuclear ***,our study indicates that maintaining low levels of hypochlorous acid plays a key role in the recovery of neurological function.

关键词： cell differentiation cerebral ischemia/reperfusion injury chlorination hypochlorous acid microglia neural stem cell neurogenesis nuclear translocation stroke β-catenin