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Cretaceous integrative stratigraphy,biotas,and paleogeographical evolution of the qinghai-Tibetan Plateau and its surrounding areas

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Science China Earth Sciences 2024年第4期67卷 1229-1289页

作者： Dangpeng XI Guobiao LI Shijun JIANG Xin RAO Tian JIANG Tianyang WANG Zuohuan qin Yasu WANG Jianzhong JIA Muhammad KAMRAN Zhongye SHI Yuyang WU Panxi WANG Lixin SUN qinggao zeng Xiaoqiao WAN State Key Laboratory of Biogeology and Environmental Geology China University of GeosciencesBeijing 100083China College of Oceanography Hohai UniversityNanjing 213200China Key Laboratory of Palaeobiology and Petroleum Stratigraphy Nanjing Institute of Geology and PaleontologyChinese Academy of SciencesNanjing 210008China State Key Laboratory of Tibetan Plateau Earth System Environmentand Resources(TPESER)Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing 100101China China National Offshore Oil Corporation Limited Beijing 100028China Shanghai Science and Technology Museum Shanghai 200120China Xizang Bureau of Geological and Mineral Exploration and Development Lhasa 850000China Tianjin Geological Survey Center of China Geological Survey Tianjin 300170China

The Cretaceous Period is a vital time interval in deciphering the evolutionary history of the Neo-Tethys Ocean and the convergence of different plates and blocks across the qinghai-Tibetan Plateau.A detailed stratigraphic framework and paleogeographic patterns are the basis for understanding the evolution of the Neo-Tethys Ocean and the formation of the qinghaiTibetan ***,the Cretaceous stratigraphy,biota,paleogeography,and major geological events in the qinghai-Tibetan Plateau are analyzed to establish an integrative stratigraphic framework,reconstruct the paleogeography during the Cretaceous Period,and decode the history of the major geological *** Cretaceous rocks of the qinghai-Tibetan Plateau and its surrounding area are predominantly marine deposits,with a small amount of interbedded marine-terrestrial and terrestrial *** Indus-Yarlung Tsangpo Suture Zone was responsible for the deposition of deep marine sediments dominated by ophiolite suites and radiolarian *** the south,the Tethys Himalayas and Indus Basin received marine sediments of varying depths and lithology;to the north,the Xigaze and Ladakh forearc basins are also filled with marine *** Lhasa Block,Karakorum Block,western Tarim Basin,and West Burma block consist of shallow marine,interbedded marine-terrestrial,and terrestrial *** Qiangtang Basin and other areas are dominated by terrestrial *** Cretaceous strata of the qinghai-Tibetan Plateau and its surrounding areas are widely distributed and diversified,with abundant foraminifera,calcareous nannofossils,radiolarians,ammonites,bivalves,and *** the basis of integrated lithostratigraphic,biostratigraphic,geochronologic,and chemostratigraphic analyses,we proposed herein a comprehensive stratigraphic framework for the Cretaceous Period of the eastern *** analyzing the Cretaceous biota of different biogeographic zones from eastern Neo-Tethys and its surrounding a

关键词： qinghai-Tibetan Plateau Tethys Cretaceous Stratigraphy Biota Paleogeography

Plasma metabolites and risk of myocardial infarction:a bidirectional Mendelian randomization study

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Journal of Geriatric Cardiology 2024年第2期21卷 219-231页

作者： Dong-Hua LI Qiang WU Jing-Sheng LAN Shuo CHEN You-Yi HUANG Lan-Jin WU Zhi-qing qin Ying HUANG Wan-Zhong HUANG Ting zeng Xin HAO Hua-Bin SU Qiang SU Department of Cardiovascular Medicine Minzu Hospital of Guangxi Zhuang Autonomous RegionGuangxiChina Senior Department of Cardiology the Sixth Medical CenterChinese PLA General HospitalBeijingChina Library of Graduate School Chinese PLA General HospitalBeijingChina Department of Cardiology Jiangbin Hospital of Guangxi Zhuang Autonomous RegionGuangxiChina Health Management Institute the Second Medical CenterChinese PLA General HospitalBeijingChina

BACKGROUND Myocardial infarction(MI)is a critical cardiovascular event with multifaceted etiology,involving several genetic and environmental *** is essential to understand the function of plasma metabolites in the development of MI and unravel its complex *** This study employed a bidirectional Mendelian randomization(MR)approach to investigate the causal relationships between plasma metabolites and MI *** used genetic instruments as proxies for plasma metabolites and MI and conducted MR analyses in both directions to assess the impact of metabolites on MI risk and vice *** addition,the large-scale genome-wide association studies datasets was used to identify genetic variants associated with plasma metabolite(1400 metabolites)and MI(20,917 individuals with MI and 440,906 individuals without MI)*** variance weighted was the primary method for estimating causal *** estimates are expressed as beta coefficients or odds ratio(OR)with 95%*** We identified 14 plasma metabolites associated with the occurrence of MI(P<0.05),among which 8 plasma metabolites[propionylglycine levels(OR=0.922,95%CI:0.881–0.965,P<0.001),gamma-glutamylglycine levels(OR=0.903,95%CI:0.861–0.948,P<0.001),hexadecanedioate(C16-DC)levels(OR=0.941,95%CI:0.911–0.973,P<0.001),pentose acid levels(OR=0.923,95%CI:0.877–0.972,P=0.002),X-24546 levels(OR=0.936,95%CI:0.902–0.971,P<0.001),glycine levels(OR=0.936,95%CI:0.909–0.964,P<0.001),glycine to serine ratio(OR=0.930,95%CI:0.888–0.974,P=0.002),and mannose to trans-4-hydroxyproline ratio(OR=0.912,95%CI:0.869–0.958,P<0.001)]were correlated with a decreased risk of MI,whereas the remaining 6 plasma metabolites[1-palmitoyl-2-arachidonoyl-GPE(16:0/20:4)levels(OR=1.051,95%CI:1.018–1.084,P=0.002),behenoyl dihydrosphingomyelin(d18:0/22:0)levels(OR=1.076,95%CI:1.027–1.128,P=0.002),1-stearoyl-2-docosahexaenoyl-GPE(18:0/22:6)levels(OR=1.067,95%CI:1.027–1.109,P=0.001),alpha-ketobutyrate levels(OR=1.108,95%

关键词： infarction alterations diagnosis

The chromosome-scale assembly of the Notopterygium incisum genome provides insight into the structural diversity of coumarins

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Acta Pharmaceutica Sinica B 2024年第8期14卷 3760-3773页

作者： Qien Li Yiqun Dai Xin-Cheng Huang Lanlan Sun Kaixuan Wang Xiao Guo Dingqiao Xu Digao Wan Latai An Zixuan Wang Huanying Tang Qi Qi Huihui zeng Minjian qin Jia-Yu Xue Yucheng Zhao Tibetan Medicine Research Center of qinghai University Tibetan Medical CollegeQinghai UniversityXining 810016China School of Pharmacy Bengbu Medical UniversityBengbu 233030China Department of Resources Science of Traditional Chinese Medicines School of Traditional Chinese PharmacyChina Pharmaceutical UniversityNanjing 210009China College of Horticulture Bioinformatics CenterAcademy for Advanced Interdisciplinary StudiesNanjing Agricultural UniversityNanjing 210095China Key Laboratory of Shaanxi Administration of Traditional Chinese Medicine for TCM Compatibility Shaanxi University of Chinese MedicineXi’an 712046China

Coumarins,derived from the phenylpropanoid pathway,represent one of the primary metabolites found in *** alignment of the tetrahydropyran(THP)and tetrahydrofuran(THF)rings with the lactone structure results in the formation of at least four types of complex ***,the mechanisms underlying the structural diversity of coumarin remain poorly ***,we report the chromosome-level genome assembly of Notopterygium incisum,spanning 1.64 Gb,with a contig N50 value of 22.7 Mb and 60,021 annotated protein-coding ***,we identified the key enzymes responsible for shaping the structural diversity of coumarins,including two p-coumaroyl CoA 2′-hydroxylases crucial for simple coumarins basic skeleton architecture,two UbiA prenyltransferases responsible for angular or linear coumarins biosynthesis,and five CYP736 cyclases involved in THP and THF ring ***,two bifunctional enzymes capable of catalyzing both demethylsuberosin and osthenol were identified for the first *** analysis implies that tandem and ectopic duplications of the CYP736 subfamily,specifically arising in the Apiaceae,contributed to the structural diversity of coumarins in ***,this study proposes a parallel evolution scenario for the complex coumarin biosynthetic pathway among different angiosperms and provides essential synthetic biology elements for the heterologous industrial production of coumarins.

关键词： Notopterygium incisum Parallel evolution Biosynthesis Pyranocoumarins Furanocoumarins

二十年来中国农村研究热点及前沿趋势(2004-2023)——以《华中师范大学学报(人文社会科学版)》重点专栏为基础的文献计量分析

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华中师范大学学报（人文社会科学版） 2024年第5期63卷 64-79页

作者：薛勤曾新华中师范大学马克思主义学院湖北武汉430079 华中师范大学教育学院湖北武汉430079

2023年12月,《华中师范大学学报(人文社会科学版)》“中国农村研究”专栏入选中宣部首批哲学社会科学期刊重点专栏。通过对2004-2023年“中国农村研究”专栏所载文章的年度发文情况、作者和来源机构等进行分析,发现该栏目持续关注“三... 详细信息

2023年12月,《华中师范大学学报(人文社会科学版)》“中国农村研究”专栏入选中宣部首批哲学社会科学期刊重点专栏。通过对2004-2023年“中国农村研究”专栏所载文章的年度发文情况、作者和来源机构等进行分析,发现该栏目持续关注“三农”问题,近二十年来陆续推出了一批优秀的学术成果,作者的来源机构地区和梯队层次分布广泛,其中高校是该领域科研成果产出的主力军,作者队伍中既有知名专家,亦不乏青年学者,包罗海内外优秀学者,国际化程度高。借助Citespace进一步分析专栏载文的高频关键词,并与《南京农业大学学报(社会科学版)》和《中国农村观察》两种期刊对比发现,“中国农村研究”专栏一直紧跟国家战略方针、关注时代前沿的核心议题,主要聚焦乡村治理、村民自治和农村改革等重要议题,体现了中国农村研究领域的前沿趋势。同时,该栏目依托本校优势学科资源,形成了以“田野政治学”为代表的特色成果。

关键词：《华中师范大学学报》 “中国农村研究”专栏中国农村研究乡村振兴

Triassic integrative stratigraphy,biotas,and paleogeographical evolution of the qinghai-Tibetan Plateau and its surrounding areas

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Science China Earth Sciences 2024年第4期67卷 1152-1194页

作者： Guichun WU Zhansheng JI Gary GLASH qinggao zeng Jianxin YAO Key Laboratory of Stratigraphy and Palaeontology Ministry of Natural ResourcesInstitute of GeologyChinese Academy of Geological SciencesBeijing 100037China SinoProbe Laboratory Chinese Academy of Geological SciencesBeijing 100094China Department of Geology and Environmental Sciences State University of New York-FredoniaFredoniaNY 14063USA Xizang Autonomous Region Geological and Mineral Exploration and Development Burea Lhasa 850010China

Rocks of the qinghai-Tibetan Plateau(QTP)host abundant Triassic *** far,the well established marine fossil sequences based on ammonoids,conodonts,bivalves,brachiopods,radiolarians,and terrestrial spora-pollen sequence have become standard for biostratigraphic correlation of the *** much of Triassic time,the QTP occupied a marine setting as suggested by the dominance of marine *** main sedimentary types represented in the Triassic successions include littoral to shallow marine clastic rocks,shallow marine carbonate platform carbonates,bathyal to abyssal slope carbonates intercalated with clastic and siliceous deposits,coal-bearing clastic strata contained within paralic facies deposits,and littoral and terrestrial volcaniclastic *** deposits are organized into four stages in ascending order:(1)Early Triassic deposits that record marine transgression,including extensive shallow marine carbonate platform strata.(2)Middle Triassic Ladinian to Late Triassic Carnian deposits,including thin-bedded limestone,fine clastics,and siliceous rocks,that accumulated at greater depths than underlying Early Triassic strata and reflect the peak of the *** activity appears to have occurred in some areas during this stage.(3)Late Triassic Norian deposits that record the onset of marine regression as suggested by the widespread occurrence of platform *** is noteworthy that stage 3 deposits of the qin-Qi-Kun area in the northernmost region of the QPT is dominated by terrestrial strata and displays evidence of local erosion.(4)Late Triassic Rhaetian littoral and shallow marine clastic and coal-bearing deposits that preserve the record of continued marine regression *** Indus-Yarlungzangbo Suture Zone(IYSZ)appears to have been the rifting axis during Triassic time as suggested by sedimentary facies trends that reflect deepening to south and ***,the Himalaya Block to the south of the IYSZ was part of the passive margin

关键词： qinghai-Tibetan Plateau Triassic Biostratigraphy Lithostratigraphy Palaeobiogeography Sedimentary palaeogeography

杜仲法呢基焦磷酸合酶EuFPS1互作蛋白筛选及分析

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植物生理学报 2024年第3期60卷 585-595页

作者：曾琴梁青赵丹贵州大学生命科学学院/农业生物工程研究院山地植物资源保护与种质创新教育部重点实验室贵阳550025

法呢基焦磷酸合酶(farnesyl diphosphate synthase,FPS)是杜仲胶生物合成途径中的关键酶之一,EuFPS1基因对杜仲胶积累有促进作用,但对其调控的分子机制尚不清楚。本研究采用SMART同源重组技术构建了杜仲酵母cDNA表达文库,以EuFPS1基因... 详细信息

法呢基焦磷酸合酶(farnesyl diphosphate synthase,FPS)是杜仲胶生物合成途径中的关键酶之一,EuFPS1基因对杜仲胶积累有促进作用,但对其调控的分子机制尚不清楚。本研究采用SMART同源重组技术构建了杜仲酵母cDNA表达文库,以EuFPS1基因为诱饵筛选互作蛋白,经测序和BLAST比对初步筛选出41个互作蛋白。GO和KEGG分析结果显示,互作蛋白主要参与卟啉化合物代谢调控、紫外线与冷响应、叶片发育等生物进程,MEP代谢、卟啉代谢、泛素介导的蛋白质水解等代谢途径。选取3个互作蛋白(EuUFM1、EuLHC1、EuKS1)进一步验证互作关系,qRT-PCR分析发现EuFPS1与EuUFM1、EuLHC1、EuKS1基因在杜仲不同组织中均表达,其中EuFPS1与EuKS1的表达呈负相关。本研究为解析杜仲EuFPS1及其与互作蛋白的作用机制奠定了基础。

关键词：杜仲法呢基焦磷酸合酶酵母双杂交互作蛋白基因表达

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考虑光伏场景聚合的配电网光储选址定容

湖南大学学报（自然科学版） 2024年第8期51卷 117-126页

作者：颜勤余国翔曾林俊长沙理工大学电气与信息工程学院湖南长沙410114 长沙理工大学能源与动力工程学院湖南长沙410114

研究光伏场景聚合是实现区域电网分布式光伏与储能联合规划的前提和基础,对促进配电网分布式光伏的充分消纳具有重要作用.通过基于改进的K-means++算法对历史光伏数据进行聚合分析,得到光伏出力的典型场景聚合,从配电网的经济性出发,兼... 详细信息

研究光伏场景聚合是实现区域电网分布式光伏与储能联合规划的前提和基础,对促进配电网分布式光伏的充分消纳具有重要作用.通过基于改进的K-means++算法对历史光伏数据进行聚合分析,得到光伏出力的典型场景聚合,从配电网的经济性出发,兼顾系统运行的可靠性、环保性,建立考虑光伏场景聚合的光储选址定容规划模型,引入层次分析法(analytic hierarchy process,AHP)将多目标优化问题转化为单目标问题,并利用粒子群算法(particle swarm optimization,PSO)进行求解.算例结果表明,提出的光伏场景聚合模型更准确刻画光伏出力的不确定性,验证了该模型的有效性和可行性.

关键词：光伏聚合分布式光伏储能电池选址定容配电网

随机与蓄意攻击下长三角城市知识网络稳健性特征及其对创新绩效的影响

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地理研究 2024年第5期43卷 1088-1106页

作者：叶琴曾刚蒋海云上海师范大学环境与地理科学学院上海200234 华东师范大学中国现代城市研究中心上海200062

新发展格局下,提升长三角城市知识网络稳健性成为积极应对全球科技合作中“逆全球化”挑战,推动高质量一体化发展的有效途径。本研究基于2017—2021年长三角41个城市的授权发明专利数据,以4位数技术类为节点,以技术组合频率为链接,构建... 详细信息

新发展格局下,提升长三角城市知识网络稳健性成为积极应对全球科技合作中“逆全球化”挑战,推动高质量一体化发展的有效途径。本研究基于2017—2021年长三角41个城市的授权发明专利数据,以4位数技术类为节点,以技术组合频率为链接,构建城市内部知识网络。通过模拟随机与蓄意攻击情景,计算网络崩溃阈值来评估长三角城市知识网络的稳健性,并采用面板计量模型探讨其对城市创新绩效的影响。研究发现:(1)长三角城市知识网络对随机攻击的抵御能力明显强于蓄意攻击。(2)长三角城市知识网络稳健性整体呈现东高西低的格局,受新冠疫情影响,出现先上升后下降态势。蓄意攻击下杭州、上海、南京、宁波知识网络稳健性排名稳居前4位,池州排名最后。(3)随机与蓄意攻击下长三角整体知识网络稳健性均高于单个城市知识网络稳健性,提高技术的跨城市、跨部门组合机会可以增强知识网络风险抵御能力。5年间长三角跨部类技术融合比例由41%上升至47%。(4)在控制知识相关多样化和非相关多样化、合作网络中心性后,回归分析结果表明城市知识网络稳健性与创新绩效呈正相关关系,且相比于随机攻击,蓄意攻击下知识网络稳健性能力对创新绩效的影响更大。将网络崩溃阈值替换为网络效能比进行稳健性检验,回归结果依然显著。最后,建议集合科技创新力量于核心技术领域,包括分离技术、电数字数据处理、测试或分析材料、清洁技术、高分子化合物等5个在知识网络中占据核心位置的技术领域,并加强城市间技术互补以提高长三角城市知识网络稳健性。

关键词：知识网络稳健性创新随机攻击蓄意攻击长三角

qGW11a/OsCAT8,encoding an amino acid permease,negatively regulates grain size and weight in rice

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The Crop Journal 2024年第4期12卷 1150-1158页

作者： Peng Gao Feifan Chen Haitang Liu Shijun Fan Jierui zeng Xue Diao Yang Liu Wencheng Song Shifu Wang Jing Li Xiaobo Zhu Bin Tu Weilan Chen Ting Li Yuping Wang Bingtian Ma Shigui Li Hua Yuan Peng qin State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China Rice Research InstituteSichuan Agricultural UniversityChengdu 611130SichuanChina

Grain size is a key factor influencing grain weight in *** this study,a chromosome segment substitution line(CSSL9-17)was identified,that exhibits a significant reduction in both grain size and weight compared to its donor parent *** investigation identified two quantitative trait loci(QTL)on chromosome 11,designated qGW11a and qGW11b,which contribute to 1000-grain weight with an additive ***_Os11g05690,encoding the amino acid permease OsCAT8,is the target gene of *** of OsCAT8 resulted in decreased grain weight,while OsCAT8 knockout mutants exhibited increased grain *** 287-bp located within the OsCAT8 promoter region of 93-11 negatively regulates its activity,which is subsequently correlated with an increase in grain size and *** results suggest that OsCAT8 functions as a negative regulator of grain size and grain weight in rice.

关键词： Rice Grain size Grain weight QTL OsCAT8