检索结果-南通市图书馆

Analysis of the anti-T2DM components in dichloromethane fraction of Schisandra sphenanthera and its mechanism

Traditional Medicine Research 2025年第1期10卷 27-43页

作者： Shi-Bo Feng Hai-Hui Jiang Hui-li Kang Yi Jiang Hua-Wei Zhang Xiao-Mei Song yu-ze li Wen-li Huang Dong-Dong Zhang Chong Deng School of Pharmacy Shaanxi University of Chinese MedicineXianyang 712046China School of Pharmacy and Shaanxi Qinling Application Development and Engineering Center of Chinese Herbal Medicine Shaanxi University of Chinese MedicineXianyang 712046China Key Laboratory for Research and Development of“Qin Medicine”of Shaanxi Administration of Traditional Chinese Medicine Xianyang 712046China Shaanxi Key Laboratory of Research and Application of“Taibai Qi Yao” Xianyang 712046China

Background:The type 2 diabetes mellitus(T2DM)pharmacodynamic study of various parts of Schisandra sphenanthera was conducted in the previous stage,and it was found that dichloromethane extracted part(SDP)had a significant hypoglycemic ***,the components of SDP were analyzed,and the specific mechanism of its anti-T2DM was ***:We used a high-fat,high-sugar diet in combination with streptozotocin to induce a T2DM rat model,and the model rats were divided into two groups according to body weight and blood ***,oral glucose tolerance test,fasting blood glucose,low density lipoprotein cholesterol,superoxide dismutase,insulin,glycated hemoglobin,total cholesterol,nonesterified free fatty acids,alanine aminotransferase,high-density lipoprotein cholesterol,aspartate aminotransferase,malondialdehyde,and glutathione peroxidase were measured,organ indices were calculated,and pathological sections of pancreas and liver were *** 16S rRNA V3–V4 region of intestinal flora was sequenced to explore the effect of SDP on biochemical indicators and intestinal *** on the above indicators,the anti-T2DM mechanism of SDP in Schisandra sphenanthera was ***:After six weeks of administration,the biochemical indices of diabetic rats were diminished compared to the control *** SDP could significantly increase the gut microbialα-diversity index,resulting in significant changes in the flora of T2DM rats,with increased richness and diversity,reduced harmful flora,and significantly back-regulated the levels of acetic acid,propionic acid,and butyric ***:SDP can improve the symptoms associated with elevated blood glucose,dyslipidemia,elevated fasting insulin levels,and damaged glucose tolerance in *** against T2DM may be through the control of intestinal flora to normalize and exert anti-diabetic effect;its main active components may be lignans and terpenoids.

关键词： Schisandra sphenanthera T2DM intestinal flora HPLC

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effect of implanting fibrin sealant with ropivacaine on pain after laparoscopic cholecystectomy

引用

World Journal of Gastroenterology 2009年第46期15卷 5851-5854页

作者： Jian-Zhu Fu Jie li ze-li yu Department of General Surgery Beijing Tongren Hospital Capital Medical University Beijing100730 China

AIM:To investigate the safety and efficacy of implant-ing fibrin sealant with sustained-release ropivacaine in the gallbladder bed for pain after laparoscopic chole-cystectomy(LC).METHODS:Sixty patients(American Society of Anes-thesiologists physical status wasⅠorⅡand underwent LC)were randomly divided into three equal groups:group A(implantation of fibrin sealant in the gallbladder bed),group B(implantation of fibrin sealant carrying ropivacaine in the gallbladder bed),and group C(normal saline in the gallbladder bed).Postoperative pain was evaluated,and pain relief was assessed by visual analog scale(VAS)***:The findings showed that 81.7%of patients had visceral pain,50%experienced parietal,and 26.7% reported shoulder pain after *** pain was significantly less in group B patients than in the other groups(P<0.05),and only one patient in this group experienced shoulder *** mean VAS score in group B patients was lower than that in the other ***:Visceral pain is prominent after LC and can be effectively controlled by implanting fibrin sealant combined with ropivacaine in the gallbladder bed.

关键词： Analgesia Fibrin sealant Laparoscopiccholecystectomy Pain Ropivacaine

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Sensitivity impacts owing to the variations in the type of zero-range pairing forces on the fission properties using the density functional theory

引用

Nuclear Science and Techniques 2024年第3期35卷 198-207页

作者： Yang Su ze-yu li li-Le liu Guo-Xiang Dong Xiao-Bao Wang Yong-Jing Chen China Nuclear Data Center China Institute of Atomic EnergyBeijing 102413China School of Science Huzhou UniversityHuzhou 313000China

Using the Skyrme density functional theory,potential energy surfaces of^(240)Pu with constraints on the axial quadrupole and octupole deformations(q_(20)and q_(30))were *** volume-like and surface-like pairing forces,as well as a combination of these two forces,were used for the Hartree–Fock–Bogoliubov *** in the least-energy fission path,fission barrier,pairing energy,total kinetic energy,scission line,and mass distribution of the fission fragments based on the different forms of the pairing forces were analyzed and *** fission dynamics were studied based on the timedependent generator coordinate method plus the Gaussian overlap *** results demonstrated a sensitivity of the mass and charge distributions of the fission fragments on the form of the pairing *** on the investigation of the neutron-induced fission of^(239)Pu,among the volume,mixed,and surface pairing forces,the mixed pairing force presented a good reproduction of the experimental data.

关键词： Nuclear fission Density functional theory Pairing force Potential energy surfaces Fission fragment distribution

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

An Ultrasensitive, Durable and Stretchable Strain Sensor with Crack-wrinkle Structure for Human Motion Monitoring

引用

Chinese Journal of Polymer Science 2021年第3期39卷 316-326,I0005页

作者： ze-yu li Wei Zhai yun-Fei yu Guo-Jie li Peng-Fei Zhan Jian-Wei Xu Guo-Qiang Zheng Kun Dai Chun-Tai liu Chang-yu Shen Shen Key Laboratory of Materials Processing and Mold(Zhengzhou University) Ministry of EducationSchool of Materials Science and EngineeringZhengzhou UniversityZhengzhou 450001China

Flexible strain sensor has promising features in successful application of health monitoring, electronic skins and smart robotics, ***, we report an ultrasensitive strain sensor with a novel crack-wrinkle structure(CWS) based on graphite nanoplates(GNPs)/thermoplastic urethane(TPU)/polydimethylsiloxane(PDMS) nanocomposite. The CWS is constructed by pressing and dragging GNP layer on TPU substrate,followed by encapsulating with PDMS as a protective layer. On the basis of the area statistics, the ratio of the crack and wrinkle structures accounts for 31.8% and 9.5%, respectively. When the sensor is stretched, the cracks fracture, the wrinkles could reduce the unrecoverable destruction of cracks, resulting in an excellent recoverability and stability. Based on introduction of the designed CWS in the sensor, the hysteresis effect is limited effectively. The CWS sensor possesses a satisfactory sensitivity(GF=750 under 24% strain), an ultralow detectable limit(strain=0.1%) and a short respond time of 90 ms. For the sensing service behaviors, the CWS sensor exhibits an ultrahigh durability(high stability>2×10^(4) stretching-releasing cycles). The excellent practicality of CWS sensor is demonstrated through various human motion tests,including vigorous exercises of various joint bending, and subtle motions of phonation, facial movements and wrist pulse. The present CWS sensor shows great developing potential in the field of cost-effective, portable and high-performance electronic skins.

关键词： Polymer nanocomposites Microstructure Flexible strain sensor Human motion monitoring

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Synthesis of Chiral α-Benzyl-β^(2)-hydroxy Carboxylic Acids through Iridium-Catalyzed Asymmetric Hydrogenation of α-Oxymethylcinnamic Acids

引用

Chinese Journal of Chemistry 2014年第8期32卷 783-787页

作者： ze-yu li Song Song Shou-Fei Zhu Na Guo li-Xin Wang Qi-lin Zhou State Key Laboratory and Institute of Elemento-Organic Chemistry Nankai UniversityTianjin 300071China Collaborative Innovation Center of Chemical Science and Engineering(Tianjin)

An asymmetric hydrogenation of α-oxymethylcinnamic acids was developed by using chiral spiro phosphineoxazoline/iridium complexes as catalysts to prepare β^(2)-hydroxycarboxylic acids with high reactivity(TON up to 2000)and excellent enantioselectivity(up to 99.5%ee).By using this highly efficient asymmetric hydrogenation as a key step,a concise total synthesis of natural product homoisoflavone(S)-(+)-4 was accomplished.

关键词： asymmetric hydrogenation chiral spiro ligands iridium catalysts α-oxymethylcinnamic acids α-benzyl-β^(2)-hydroxy carboxylic acids

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Compressive sensing SAR range compression with chirp scaling principle

引用

Science China(Information Sciences) 2012年第10期55卷 2292-2300页

作者： XIAO Peng,yu ze & li ChunSheng School of Electronics and Information Engineering,Beihang University,Beijing 100191,China School of Electronics and Information Engineering Beihang University Beijing China

Compressive sensing(CS) techniques offer a framework for the detection and allocation of sparse signal with a reduced number of *** paper proposes a novel SAR range compression,namely compressive sensing with chirp scaling(CS-CS),achieving the same range resolution as conventional SAR approach,while using fewer range *** order to realize accurate range cell migration correction(RCMC),chirp scaling principle is used to construct reference matrix for compressive sensing ***,error diagrams are designed for measurement of the performance of CS-CS,and some experiments of using real data are performed to deal with the errors caused by three conditions:SNR,sparsity and sampling.

关键词： synthetic aperture radar compressive sensing range cell migration correction error radar signal processing

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Anomalous pancreaticobiliary junction: image analysis and treatment principles

引用

Hepatobiliary & Pancreatic Diseases International 2004年第1期3卷 136-139页

作者： ze-li yu, li-Jun Zhang, Jian-Zhu Fu, Jie li, Qing-yu Zhang and Fou-Lai Chen Beijing, China Department of General Surgery, Beijing Tongren Hospital, Capital University of Medical Sciences, Beijing 100730, China Department of General Surgery Beijing Tongren Hospital Capital University of Medical Sciences Beijing 100730 China. zhlj1968@***

BACKGROUND: Anomalous pancreaticobiliary junction is often associated with biliary tract carcinoma and acute pan- creatitis. We assessed the value of image analysis in the diag- nosis of patients with anomalous pancreaticobiliary junction (APBJ) and the principles for the treatment of APBJ. METHODS: Sixty-four patients with APBJ were subjected to ultrasound imaging, endoscopic retrograde cholangio- pancreatography (ERCP) and magnetic resonance cholan- giopancreatography (MRCP) before surgery. The diagnos- tic accuracy of image analysis and their surgical outcomes were evaluated retrospectively. RESULTS: On ERCP and MRCP, the length of the com- mon channel was calculated to be 15 mm or longer in all patients, and the angle of the junction was more than 75° in 49 (76.6%) of the 64 patients. Of the 64 patients, 28 were defined of pancreatic duct type (P-C) (28/64, 43.75%), 32 bile duct type (C-P) (32/64, 50%), and 4 common chan- nel type (4/64, 6.25%). CONCLUSIONS: Patients with APBJ are often associated with biliary tract and pancreatic diseases, and early detec- tion and correct surgical treatment could avoid serious complications. ERCP and MRCP are accurate in the diag- nosis of APBJ.

关键词： anomalous pancreaticobiliary junction image examination surgical treatment

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Generation and regulation of electromagnetic pulses generated by femtosecond lasers interacting with multitargets

引用

Nuclear Science and Techniques 2024年第1期35卷 96-107页

作者： Ya-Dong Xia De-Feng Kong Qiang-You He Zhen Guo Dong-Jun Zhang Tong Yang Hao Cheng yu-ze li Yang Yan Xiao liang Ping Zhu Xing-Long Xie Jian-Qiang Zhu Ting-Shuai li Chen lin Wen-Jun Ma Xue-Qing Yan State Key Laboratory of Nuclear Physics and Technology and Key Laboratory of HEDP of the Ministry of EducationCAPTPeking UniversityBeijing 100871China Beijing Laser Acceleration Innovation Center Beijing 101407China Institute of Guangdong Laser Plasma Technology Guangzhou 510540China National Laboratory on High Power Laser and Physics Shanghai Institute of Optics and FineChinese Academy of SciencesShanghai 201800China School of Materials and Energy University of Electronic Science and Technology of ChinaChengdu 611731China

Ultrashort and powerful laser interactions with a target generate intense wideband electromagnetic pulses(EMPs).In this study,we report EMPs generated by the interactions between petawatt(30 fs,1.4×10^(20) W/cm^(2))femtosecond(fs)lasers with metal flat,plastic flat,and plastic nanowire-array(NWA)*** analyses are conducted on the EMPs in terms of their spatial distribution,time and frequency domains,radiation energy,and *** results indicate that EMPs from metal targets exhibit larger amplitudes at varying angles than those generated by other types of targets and are enhanced significantly for NWA *** a plastic target holder and increasing the laser focal spot can significantly decrease the radiation energy of the ***,the composite shielding materials indicate an effective shielding effect against *** simulation results show that the NWA targets exert a collimating effect on thermal electrons,which directly affects the distribution of *** study provides guidance for regulating EMPs by controlling the laser focal spot,target parameters,and target rod material and is beneficial for electromagnetic-shielding design.

关键词： Electromagnetic pulses Laser plasma interaction Electromagnetic shielding Electron distribution

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

鼠笼支撑一体化结构对薄壁球轴承承载性能的影响

引用

吉林大学学报（工学版） 2018年第5期48卷 1508-1514页

作者：毛宇泽王黎钦哈尔滨工业大学机电工程学院哈尔滨150001

建立了鼠笼柔性支撑一体化轴承的FEM-拟动力学迭代分析模型,采用FEM模型计算支撑结构和轴承滚道的变形,采用非圆滚道的拟动力学模型分析轴承动态特性。研究了一个鼠笼支撑一体化球轴承在载荷作用下的内部载荷分布,分析了柔性支撑一体化... 详细信息

建立了鼠笼柔性支撑一体化轴承的FEM-拟动力学迭代分析模型,采用FEM模型计算支撑结构和轴承滚道的变形,采用非圆滚道的拟动力学模型分析轴承动态特性。研究了一个鼠笼支撑一体化球轴承在载荷作用下的内部载荷分布,分析了柔性支撑一体化结构对球轴承动态特性的影响。结果表明,鼠笼支撑一体化结构使轴承内部最大接触载荷减小了10.94%,疲劳寿命增加了11.3%,轴承刚度大幅降低,打滑率上升了15.8%。并且,轴承套圈壁厚越厚,结果越接近刚性支撑假设的计算结果;轴承套圈壁厚越薄,鼠笼支撑带来的影响越显著。

关键词：机械设计及理论滚动轴承鼠笼支撑结构变形载荷分布疲劳寿命

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Three-dimensional potential energy surface for fission of^(236)U within covariant density functional theory

引用

Chinese Physics C 2023年第6期47卷 143-149页

作者：周明晖李泽宇陈盛远陈永静李志攀 School of Physical Science and Technology Southwest UniversityChongqing 400715China China Nuclear Data Center China Institute of Atomic EnergyBeijing 102413China

We calculate the three-dimensional potential energy surface(PES)for the fission of the compound nucleus^(236)U using covariant density functional theory with constraints on the axial quadrupole and octupole deformations(β_(2),β_(3))coexistence of the elongated and compact fission modes is predicted for comes shallow across a large range of quadrupole and octupole deformations for small scission line in the(β_(2),β_(3))plane extends to a shallow band,leading to fluctuations of several to ten MeV in the estimated total kinetic energies and of several to approximately ten nucleons in the fragment masses.

关键词： multi-dimensional potential energy surface covariant density functional theory scission total kinetic energy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：