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Mazabraud’s syndrome in female patients:Two case reports

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World Journal of Orthopedics 2024年第6期15卷 593-601页

作者： Xiu-Mao Li ze-Hao Chen Ke-Yi Wang Jun-Nan Chen Zhao-Nong yao Yu-Hong yao Xiao-Wei Zhou Nong Lin Department of Orthopedics The Second Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhou 310009Zhejiang ProvinceChina Orthopedics Research Institute Zhejiang UniversityHangzhou 310009Zhejiang ProvinceChina State Key Laboratory of Transvascular Implantation Devices Hangzhou 310009Zhejiang ProvinceChina Songyang Branch of the Second Affiliated Hospital School of MedicineZhejiang UniversityLishui 331124Zhejiang ProvinceChina

BACKGROUND Mazabraud’s syndrome(MS)is a rare and slowly progressive benign disease characterized by the concurrent presence of fibrous dysplasia of bone and intramuscular myxoma,and is thought to be associated with mutations of the GNAS *** date,only about 100 cases of MS have been reported in the literature,but its standard treatment strategy remains *** SUMMARY We report two cases of MS in young women who underwent different treatments based on their symptoms and disease *** first patient,aged 37,received internal fixation and intravenous bisphosphonate for a pathological fracture of the right femoral neck,excision of a right vastus medialis myxoma was subsequently performed for pain control,and asymptomatic psoas myxomas were monitored without *** testing confirmed a GNAS gene mutation in this *** second patient,aged 24,underwent right vastus intermedius muscle myxoma resection,and conservative treatment for fibrous dysplasia of the *** patients were followed-up for 17 months and 3 years,respectively,and are now in a stable *** Various treatments have been selected for MS patients who suffer different *** main treatment for myxomas is surgical resection,while fibrous dysplasia is selectively treated if the patient experiences pathological fracture or severe ***,given the documented instances of malignant transformation of fibrous dysplasia in individuals with MS,close follow-up is necessary.

关键词： Mazabraud's syndrome Fibrous dysplasia Intramuscular myxoma Bisphosphonate Case report

Reinforcement learning based adaptive control for uncertain mechanical systems with asymptotic tracking

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Defence Technology（防务技术） 2024年第4期34卷 19-28页

作者： Xiang-long Liang Zhi-kai yao yao-wen Ge Jian-yong yao School of Mechanical Engineering Nanjing University of Science and TechnologyNanjing210094China College of Automation&College of Artificial Intelligence Nanjing University of Post and TelecommunicationNanjing210023China

This paper mainly focuses on the development of a learning-based controller for a class of uncertain mechanical systems modeled by the Euler-Lagrange *** considered system can depict the behavior of a large class of engineering systems,such as vehicular systems,robot manipulators and *** these systems are often characterized by highly nonlinear characteristics,heavy modeling uncertainties and unknown perturbations,therefore,accurate-model-based nonlinear control approaches become *** by the challenge,a reinforcement learning(RL)adaptive control methodology based on the actor-critic framework is investigated to compensate the uncertain mechanical *** approximation inaccuracies caused by RL and the exogenous unknown disturbances are circumvented via a continuous robust integral of the sign of the error(RISE)control *** from a classical RISE control law,a tanh(·)function is utilized instead of a sign(·)function to acquire a more smooth control *** developed controller requires very little prior knowledge of the dynamic model,is robust to unknown dynamics and exogenous disturbances,and can achieve asymptotic output ***,co-simulations through ADAMS and MATLAB/Simulink on a three degrees-of-freedom(3-DOF)manipulator and experiments on a real-time electromechanical servo system are performed to verify the performance of the proposed approach.

关键词： Adaptive control Reinforcement learning Uncertain mechanical systems Asymptotic tracking

Estimating wheat spike-leaf composite indicator(SLI)dynamics by coupling spectral indices and machine learning

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The Crop Journal 2024年第3期12卷 927-937页

作者： Haiyu Tao Ruiheng Zhou Yining Tang Wanyu Li Xia yao Tao cheng Yan Zhu Weixing Cao Yongchao Tian National Engineering and Technology Center for Information Agriculture Key Laboratory of Crop System Analysis and Decision MakingMinistry of Agriculture and Rural AffairsJiangsu Key Laboratory for Information AgricultureNanjing Agricultural UniversityNanjing 210095JiangsuChina

The contribution of spike photosynthesis to grain yield(GY)has been overlooked in the accurate spectral prediction of ***,it’s essential to construct and estimate a yield-related phenotypic trait considering spike *** on field and spectral reflectance data from 19 wheat cultivars under two nitrogen fertilization conditions in two years,our objectives were to(i)construct a yield-related phenotypic trait(spike–leaf composite indicator,SLI)accounting for the contribution of the spike to photosynthesis,(ii)develop a novel spectral index(enhanced triangle vegetation index,ETVI3)sensitive to SLI,and(iii)establish and evaluate SLI estimation models by integrating spectral indices and machine learning *** results showed that SLI was sensitive to nitrogen fertilizer and wheat cultivar variation as well as a better predictor of yield than the leaf area ***3 maintained a strong correlation with SLI throughout the growth stage,whereas the correlations of other spectral indices with SLI were poor after spike *** spectral indices and machine learning algorithms improved the estimation accuracy of SLI,with the most accurate estimates of SLI showing coefficient of determination,root mean square error(RMSE),and relative RMSE values of 0.71,0.047,and 26.93%,*** results provide new insights into the role of fruiting organs for the accurate spectral prediction of *** high-throughput SLI estimation approach can be applied for wheat yield prediction at whole growth stages and may be assisted with agronomical practices and variety selection.

关键词： Wheat spike photosynthesis Yield-related phenotypic trait Spectral indices Machine learning Estimation

Ce-and La-doped polymetallic layered double hydroxides for enhanced oxygen evolution reaction performance at high current density

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Science China Chemistry 2024年第8期67卷 2586-2598页

作者： Rinel R.Kimaka P. Ping Wang Miao He Senyao Meng Jiasai yao Huawei Li cheng Yang Zhenxing Li State Key Laboratory of Heavy Oil Processing College of New Energy and MaterialsChina University of Petroleum(Beijing)Beijing 102249China

Polymetallic layered double hydroxides are promising cost-effective catalysts for the oxygen evolution reaction(OER) due to their versatile anionic and cationic tunability. Nevertheless, several challenges persist, notably, issues related to low electrical conductivity, poor catalytic activity, and stability, especially at high current density. Herein, we report the design of Ce-and Ladoped Co Ni Fe-layered double hydroxide(Ce La Co Ni Fe-LDH) nanosheets through a facile and scalable in situ self-assembly strategy that displays enhanced OER activity. Experimental and theoretical investigations provide insights into the impact of Ceand La-doping by comparing Ce Co Ni Fe-LDH, La Co Ni Fe-LDH, and pristine Co Ni Fe-LDH, all synthesized using the same methodology. These results reveal that doping Ce^(3+)and La^(3+)into Co Ni Fe-LDH substantially improves its electronic structure,resulting in enhanced conductivity, more oxygen vacancies(Vo), electron interaction, and active site formation. Consequently,significantly reduced overpotentials of 175, 314, and 424 m V at 10, 100, and 500 m A cm^(-2), respectively, and a highly stable current density of 120 h in 1 M KOH were achieved. Notably, these performance metrics surpass those of unmodified LDHs and are competitive with many lanthanide-doped transition metal-based LDH electrocatalysts, as well as noble metal catalysts like ruthenium catalysts. This work represents a pioneering effort in doping Ce^(3+)and La^(3+)ions into a functional Co Ni Fe-based electrocatalyst, offering inspiring OER performance and scalability potential.

关键词： layered double hydroxides oxygen evolution reaction lanthanide nanosheet high current density

Effect of preload forces on multidimensional signal dynamic behaviours for battery early safety warning

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Journal of Energy Chemistry 2024年第5期92卷 484-498页

作者： Kuijie Li Jiahua Li Xinlei Gao yao Lu Depeng Wang Weixin Zhang Weixiong Wu Xuebing Han Yuan-cheng Cao Languang Lu Jinyu Wen Shijie cheng Minggao Ouyang School of Electrical and Electronic Engineering Huazhong University of Science and TechnologyWuhan 430074HubeiChina State Key Laboratory of Automotive Safety and Energy Tsinghua UniversityBeijing 100084China Energy and Electricity Research Center Jinan UniversityZhuhai 519070GuangdongChina Department of Mechanical Engineering Imperial College LondonLondon.SW7:2AZ.UK

Providing early safety warning for batteries in real-world applications is *** this study,comprehensive thermal abuse experiments are conducted to clarify the multidimensional signal evolution of battery failure under various preload *** time-sequence relationship among expansion force,voltage,and temperature during thermal abuse under five categorised stages is *** characteristic peaks are identified for the expansion force,which correspond to venting,internal short-circuiting,and thermal *** particular,an abnormal expansion force signal can be detected at temperatures as low as 42.4°C,followed by battery thermal runaway in approximately 6.5 ***,reducing the preload force can improve the effectiveness of the early-warning method via the expansion ***,reducing the preload force from 6000 to 1000 N prolongs the warning time(i.e.,227 to 398 s)before thermal runaway is *** on the results,a notable expansion force early-warning method is proposed that can successfully enable early safety warning approximately 375 s ahead of battery thermal runaway and effectively prevent failure propagation with module *** study provides a practical reference for the development of timely and accurate early-warning strategies as well as guidance for the design of safer battery systems.

关键词： Lithium-ion battery Thermal runaway Preload force Expansionforce Early warning Multidimensional signal

Dynamic changes of rumen microbiota and serum metabolome revealed increases in meat quality and growth performances of sheep fed bio‑fermented rice straw

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Journal of Animal Science and Biotechnology 2024年第3期15卷 1207-1226页

作者： Yin Yin Kyawt Min Aung yao Xu Zhanying Sun Yaqi Zhou Weiyun Zhu Varijakshapanicker Padmakumar Zhankun Tan Yanfen cheng Laboratory of Gastrointestinal Microbiology National Center for International Research on Animal Gut NutritionNanjing Agricultural UniversityNanjing 210095China Department of Animal Nutrition University of Veterinary ScienceNay Pyi Taw 15013Myanmar International Livestock Research Institute Nairobi 00100Kenya College of Animal Science Tibet Academy of Agricultural and Animal Husbandry SciencesLhasa 850000China State Key Laboratory of Grassland Agro‑Ecosystems Center for Grassland MicrobiomeCollege of Pastoral Agriculture Science and TechnologyLanzhou UniversityLanzhou 730000China

Background Providing high-quality roughage is crucial for improvement of ruminant production because it is an essential component of their *** previous study showed that feeding bio-fermented rice straw(BF)improved the feed intake and weight gain of ***,it remains unclear why feeding BF to sheep increased their feed intake and weight ***,the purposes of this research were to investigate how the rumen micro-biota and serum metabolome are dynamically changing after feeding BF,as well as how their changes influence the feed intake,digestibility,nutrient transport,meat quality and growth performances of *** growing Hu sheep were allocated into 3 groups:alfalfa hay fed group(AH:positive control),rice straw fed group(RS:negative control)and BF fed group(BF:treatment).Samples of rumen content,blood,rumen epithelium,muscle,feed offered and refusals were collected for the subsequent *** Feeding BF changed the microbial community and rumen fermentation,particularly increasing(P<0.05)relative abundance of Prevotella and propionate production,and decreasing(P<0.05)enteric methane *** histomorphology(height,width,area and thickness)of rumen papillae and gene expression for carbohydrate trans-port(MCT1),tight junction(claudin-1,claudin-4),and cell proliferation(CDK4,Cyclin A2,Cyclin E1)were improved(P<0.05)in sheep fed ***,serum metabolome was also dynamically changed,which led to up-regulating(P<0.05)the primary bile acid biosynthesis and biosynthesis of unsaturated fatty acid in sheep fed *** a result,the higher(P<0.05)feed intake,digestibility,growth rate,feed efficiency,meat quality and mono-unsaturated fatty acid concentration in muscle,and the lower(P<0.05)feed cost per kg of live weight were achieved by feeding *** Feeding BF improved the growth performances and meat quality of sheep and reduced their feed ***,bio-fermentation of rice straw could be an innovative way for improving rum

关键词： Bio-fermentation Growth rate Meat quality Metabolome Microbiota Rice straw

Metalenses phase characterization by multidistance phase retrieval

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Light(Science & Applications) 2024年第9期13卷 1898-1907页

作者： Bowen Liu Jialuo cheng Maoxiong Zhao Jin yao Xiaoyuan Liu Shaohu Chen Lei Shi Din Ping Tsai Zihan Geng Mu Ku Chen State Key Laboratory of Surface Physics Key Laboratory of Micro-and Nano-Photonic Structures(Ministry of Education)and Department of PhysicsFudan University200433 ShanghaiChina Department of Electrical Engineering City University of Hong KongKowloonHong Kong SARChina State Key Laboratory of Terahertz and Millimeter Waves City University of Hong KongKowloonHong Kong SARChina Institute for Nanoelectronic Devices and Quantum Computing Fudan University200438 ShanghaiChina Collaborative Innovation Center of Advanced Microstructures Nanjing University210093 NanjingJiangsuChina Shanghai Research Center for Quantum Sciences 201315 ShanghaiChina Centre for Biosystems Neuroscienceand NanotechnologyCity University of Hong KongKowloonHong Kong SARChina Institute of Data and Information Tsinghua Shenzhen International Graduate SchoolTsinghua University518071 ShenzhenGuangdongChina

Metalens,characterized by their unique functions and distinctive physical properties,have gained significant attention for their potential *** further optimize the performance of metalens,it is necessary to characterize the phase modulation of the *** this study,we present a multi-distance phase retrieval system based on optical field scanning and discuss its convergence and *** findings indicate that the system is capable of retrieving the phase distribution of the metalens as long as the measurement noise is low and the total length of the scanned light field is sufficiently *** system enables the analysis of focal length and aberration by utilizing the computed phase *** extend our investigation to measure the phase distribution of the metalens operating in the near-infrared(NIR)spectrum and identify the impact of defects in the sample on the ***,we conduct a comparative analysis of the phase distribution of the metalens in air and ethanol and observe the variations in the phase modulation of the metalens in different working *** system provides a straightforward method for the phase characterization of metalens,aiding in optimizing the metalens design and functionality.

关键词： phase system distribution

Light-responsive Self-Immolative L-glutamic Acid-based Polyester Nanoparticles for Controlled Drug Release via Passerini Three-Component Polymerization

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Chinese Journal of Polymer Science 2024年第5期42卷 570-578,I0005页

作者： Xiao-Fei Sun Xu Zhang Shu-Ping Song Ya-Qun yao Yan Zhang cheng-Liang Wang Jing-Jiang Sun Qing-Fu Wang Key Laboratory of Rubber-plastics Ministry of EducationSchool of Polymer Science and EngineeringQingdao University of Science and TechnologyQingdao266042China Qingdao Research Academy of Environmental Science Qingdao266012China

L-glutamic acid(LA)is a bio-based,non-toxic,environmentally friendly material derived from *** present study reports the application of Passerini three-component polymerization(P-3CP)for the straightforward preparation of LA-based light-responsive polyesters(PLTDs)under mild *** with molar masses up to 8500 g/mol and high yields exceeding 90%are *** chemical structures and light-responsive self-immolative behavior of PLTDs are comprehensively characterized by employing ultraviolet-visible(UV-Vis)spectroscopy,size exclusion chromatography(SEC),nuclear magnetic resonance(NMR)spectroscopy,and liquid chromatography mass spectrometry(LC-MS).Meanwhile,monodisperse PLTD-based doxorubicin-loaded nanoparticles(PLTD-DOX-NP)(size=193 nm,PDI=0.018)are formulated by nanoprecipitation *** light-induced depolymerization,the PLTD-DOX-NP undergoes rapid decomposition,resulting in a burst release of 80%cargo within 13 ***,according to biological toxicity tests,the PLTD-NP possesses adequate biosafety,both before and after ***,the incorporation of P-3CP with biorenewable LA-based monomer adheres to the principles of green chemistry,significantly simplifying the synthetic pathway of light-responsive polymers.

关键词： L-glutamic acid Passerini three-component polymerization Light-responsive Polyester Nanoparticles

Flexible MXene/sodium alginate composite fabric with high structural stability and oxidation resistance for electromagnetic interference shielding

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Nano Research 2024年第6期17卷 5326-5335页

作者： Hao-Wen Zhang Lu-yao Yang Meng-Lin Huang Ming-Hua cheng Zhe-Sheng Feng Fanbin Meng Zifeng Lin Yan Wang School of Materials and Energy University of Electronic Science and Technology of ChinaChengdu 610054China Laboratory of Advanced Technologies of Materials(Ministry of Education) School of Materials Science and EngineeringSouthwest Jiaotong UniversityChengdu 610031China College of Materials Science and Engineering Sichuan UniversityChengdu 610065China

Wearable electromagnetic interference(EMI)shielding fabrics with excellent electromagnetic shielding performance,oxidation resistance,and structural stability are highly demanded for the rapid development of electronic devices and wireless *** are metallic conductive materials with exceptional EMI shielding properties,but they are prone to oxidation in air and have poor structural stability and durability on fabric ***,we present a one-step assembly method to fabricate fabrics coated with MXenes and polymeric sodium alginate(SA)composite(MXene-SA).SA protects MXenes from oxidation and forms a stable interlayer structure by bonding to *** MXene-SA coated fabrics are breathable and flexible,and have a low sheet resistance of 2.12±0.08Ω/sq and a high EMI shielding performance of 37.05 dB at X-band,which is comparable to the best 42.31 ***,the MXene-SA coated fabrics exhibit high structural stability and oxidation resistance under various conditions of sonication disintegration,mechanical abuse,chemical corrosion,and humidity,compared to pure MXenes coated *** believe that the wearable and high-performance MXene-SA fabrics have great potential for the next generation of ultra-portable and wearable EMI shielding products.

关键词： MXenes electromagnetic interference shielding fabric one-step assembly