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科技计划项目监督管理模式创新研究——以安徽省为例

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华东经济管理 2015年第12期29卷 171-175页

作者：刘赞扬聂中生安徽省科学技术厅安徽省科学技术情报研究所安徽合肥230011

文章在分析加强科技计划项目监督管理的重要性和必要性、考察国内外开展科技计划项目监管的特点与经验、总结安徽省科技计划项目监督管理的实践与探索基础上,重点研究了安徽省重大科技项目(专项)、安徽省创业投资引导基金、科技计划项... 详细信息

文章在分析加强科技计划项目监督管理的重要性和必要性、考察国内外开展科技计划项目监管的特点与经验、总结安徽省科技计划项目监督管理的实践与探索基础上,重点研究了安徽省重大科技项目(专项)、安徽省创业投资引导基金、科技计划项目评估评审绩效评价三种监督管理创新模式,提出了加强安徽省科技计划项目监督管理的政策建议。

关键词：科技计划项目监督管理模式创新

Work-function effect of Ti_(3)C_(2)/Fe-N-C inducing solid electrolyte interphase evolution for ultra-stable sodium storage

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Nano Research 2024年第8期17卷 7163-7173页

作者： Huicong Xia Lingxing zan Hongliang Dong Yifan Wei Yue Yu Jinfu Shu Jia-Nan Zhang Chong-Xin Shan Key Laboratory of Advanced Energy Catalytic and Functional Material Preparation of Zhengzhou College of Materials Science and EngineeringZhengzhou UniversityZhengzhou 450001China Key Laboratory of Materials Physics of Ministry of Education School of Physics and MicroelectronicsZhengzhou UniversityZhengzhou 450001China Key Laboratory of Chemical Reaction Engineering of Shaanxi Province College of Chemistry and Chemical EngineeringYan’an UniversityYan’an 716000China Center for High Pressure Science and Technology Advanced Research PudongShanghai 201203China Key Laboratory of Advanced Energy Materials Chemistry(Ministry of Education) Nankai UniversityTianjin 300071China

In the quest to enhance the efficiency of sodium-ion batteries,the dynamics of solid electrolyte interphase(SEI)formation are of paramount *** SEI layer’s integrity is integral to the charge–discharge efficiency and the overall longevity of the ***,a novel two-dimensional Ti_(3)C_(2) fragments enmeshed on iron-nitrogen-carbon(Fe-N-C)nanosheets(Ti_(3)C_(2)/Fe-NC)has been *** electrode features a matrix which has been shown to expedite SEI layer formation through the facilitation of selective anion adsorption,thus augmenting battery *** functional theory calculation reveals that the SEI evolution energy of NaPF6 at the Ti_(3)C_(2)/Fe-N-C interface is 0.81 eV,significantly lower than the Ti_(3)C_(2)(1.23 eV).This process is driven by the electron transportation from Ti_(3)C_(2) to Fe-N-C substrate,facilitated by their work-function difference,leading to the formation of ferromagnetic Fe species,which possesses Fe 3d d_(xz)d_(z)2 orbitals and undergoes hybridization with theπandσorbitals of NaF,creating a key intermediate during *** process diminishes the antibonding energy and attenuates the orbital interaction with NaF,thus reducing the activation energy and improving the SEI formation reaction ***,it leads to the creation of multi-interface SEI characterized by high-throughput ion transport and an efficient reaction network.

关键词： Ti_(3)C_(2)/Fe-N-C heterostructure work-function electron interaction solid electrolyte interphase sodium storage

公铁货流转移下铁路车流径路与列车编组计划联合优化

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交通运输系统工程与信息 2022年第5期22卷 19-25,36页

作者：王志美姚尚君崔赞扬北京交通大学交通运输学院北京100044

促进更多货流从公路转移到铁路是实现“双碳”目标的重要路径之一,也是推动铁路高质量发展的关键举措。鉴于此,本文以公铁货流转移量、铁路车流径路选择及编组去向等为主要决策变量,以公铁两网物流总成本极小化为目标,构建公铁货流转移... 详细信息

促进更多货流从公路转移到铁路是实现“双碳”目标的重要路径之一,也是推动铁路高质量发展的关键举措。鉴于此,本文以公铁货流转移量、铁路车流径路选择及编组去向等为主要决策变量,以公铁两网物流总成本极小化为目标,构建公铁货流转移量与铁路车流径路及列车编组计划联合优化模型,实现“公转铁”货流全过程、多阶段运输费用的数学表达,得到系统优化的OD间公铁货流转移量、车流走行径路和改编站点。针对模型的非线性特征,引入辅助0-1变量进行线性化,将其转化为混合整数线性规划模型,为验证模型有效性设计算例,借助数学规划优化器GUROBI进行求解。结果表明,模型可为公铁货流转移方案配置合理的接驳路径和列车编组方案;相较于既有研究,本文构建模型考虑了公铁两端的接驳转运费用和铁路车流集结与改编费用,使得“公转铁”物流总成本增加了约23.06%,转移货流量降低了约4.91%,更准确地描述了公铁货流转移过程,为制定“公转铁”运输方案和组织措施提供一定的理论依据。

关键词：铁路运输车流组织车流径路编组计划树形径路

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中国住房的双重属性:消费和投资的视角

经济研究 2014年第A1期49卷 55-65页

作者：杨赞张欢赵丽清清华大学恒隆房地产研究中心清华大学建设管理系邮政编码100084

本文基于住房消费和投资的双重属性,通过构建跨期消费效用和投资组合模型,分析了住房价格影响家庭消费的微观机制,并基于中国房地产市场的特性,建立了针对家庭差异以及区域差异的住房—消费关系的理论假设,利用城镇居民的微观调研数据... 详细信息

本文基于住房消费和投资的双重属性,通过构建跨期消费效用和投资组合模型,分析了住房价格影响家庭消费的微观机制,并基于中国房地产市场的特性,建立了针对家庭差异以及区域差异的住房—消费关系的理论假设,利用城镇居民的微观调研数据和区域宏观数据进行了实证检验。本文发现,对于住房所有者而言,由于住房消费和投资的双重属性,及其难以分割性,拥有住房不仅需要支付住房使用成本,同时也需要支付住房投资的机会成本,而两者的相对值是影响住房—消费关系的重要因素。在此基础上,本文发现住房价格对单套和多套住房家庭消费的影响相对一致,但是却呈现出明显的区域差异,这与中国住房市场普遍缺乏房产税,住房价格波动区域差异显著的特点相一致。

关键词：住房消费和投资住房价格居民消费区域差异

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锆硅渣动态水热合成硬硅钙石的研究

人工晶体学报 2014年第4期43卷 997-1002,1008页

作者：苏振杨赞中赵田田王涵山东理工大学材料科学与工程学院淄博255091

以氧氯化锆生产排放的酸性锆硅渣为主要原料,经脱酸除杂得到硅凝胶,按nCaO∶nSiO2=1∶1、W∶S（水/固质量比）=30∶1与消石灰加水混合均匀,采用动态水热法合成硬硅钙石。利用XRD、FT-IR、SEM等方法,研究了硬硅钙石的合成条件和合成机理... 详细信息

以氧氯化锆生产排放的酸性锆硅渣为主要原料,经脱酸除杂得到硅凝胶,按nCaO∶nSiO2=1∶1、W∶S（水/固质量比）=30∶1与消石灰加水混合均匀,采用动态水热法合成硬硅钙石。利用XRD、FT-IR、SEM等方法,研究了硬硅钙石的合成条件和合成机理。结果表明,锆硅渣经消石灰中和水洗可有效脱酸除杂,并可降低硅凝胶的[SiO4]4-聚合度,提高其反应活性。用此硅凝胶作硅源,在200℃下反应6 h即可合成长径比为40~60的纯相纤维状硬硅钙石。反应过程中,硬硅钙石系由CSH凝胶直接转化而成,未经历托贝莫来石相的过渡。

关键词：动态水热法锆硅渣硬硅钙石 [SiO4]4-聚合度合成机理

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基于GPRS的配电变压器监测系统

自动化与仪表 2009年第4期24卷 22-25页

作者：杨赞伟阳春华中南大学信息科学与工程学院长沙410083

针对配电变压器监测系统对数据传输可靠性和实时性的要求,提出了一种基于通用分组无线业务(GPRS)的配电变压器监测系统,实现了真正意义上的远程无线配变监测。系统的配变监测终端主处理器选用32位的ARM LPC2210,通过GPRS通信网络对数据... 详细信息

针对配电变压器监测系统对数据传输可靠性和实时性的要求,提出了一种基于通用分组无线业务(GPRS)的配电变压器监测系统,实现了真正意义上的远程无线配变监测。系统的配变监测终端主处理器选用32位的ARM LPC2210,通过GPRS通信网络对数据进行在线召测,采用基于CRC校验的密码安全算法保障数据传输安全性。现场运行结果表明,本系统具有实时性、可靠性高、传输速率快的特点。

关键词：通用分组无线业务配电变压器监测终端循环校验

METTL14 downregulation drives S100A4^(+)monocyte-derived macrophages via MyD88/NF-κB pathway to promote MAFLD progression

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Signal Transduction and Targeted Therapy 2024年第5期9卷 2176-2192页

作者： Yue-fan Wang Wen-li Zhang Zhi-xuan Li Yue Liu Jian Tan Hao-zan Yin Zhi-chao Zhang Xian-jie Piao Min-hao Ruan Zhi-hui Dai Si-jie Wang Chen-yang Mu Ji-hang Yuan Shu-han Sun Hui Liu Fu yang The Third Department of Hepatic Surgery Eastern Hepatobiliary Surgery Hospital Affiliated to Naval Medical University200438 ShanghaiChina The Department of Medical Genetics Naval Medical University200433 ShanghaiChina Translational Medicine Research Center Medical Innovation Research Division and Fourth Medical Center of the Chinese PLA General Hospital100048 BeijingChina The Department of Pharmaceutical Analysis School of PharmacyNaval Medical University200433 ShanghaiChina Key Laboratory of Biosafety Defense Ministry of Education200433 ShanghaiChina Shanghai Key Laboratory of Medical Biodefense 200433 ShanghaiChina

Without intervention,a considerable proportion of patients with metabolism‐associated fatty liver disease(MAFLD)will progress from simple steatosis to metabolism‐associated steatohepatitis(MASH),liver fibrosis,and even hepatocellular ***,the molecular mechanisms that control progressive MAFLD have yet to be fully ***,we unraveled that the expression of the N6-methyladenosine(m6A)methyltransferase METTL14 is remarkably downregulated in the livers of both patients and several murine models of MAFLD,whereas hepatocyte-specific depletion of this methyltransferase aggravated lipid accumulation,liver injury,and ***,hepatic Mettl14 overexpression alleviated the above pathophysiological changes in mice fed on a high-fat diet(HFD).Notably,in vivo and in vitro mechanistic studies indicated that METTL14 downregulation decreased the level of GLS2 by affecting the translation efficiency mediated by YTHDF1 in an m6A-depedent manner,which might help to form an oxidative stress microenvironment and accordingly recruit Cx3cr1^(+)Ccr2^(+)monocyte-derived macrophages(Mo-macs).In detail,Cx3cr1^(+)Ccr2^(+)Mo-macs can be categorized into M1-like macrophages and S100A4-positive macrophages and then further activate hepatic stellate cells(HSCs)to promote liver *** experiments revealed that CX3CR1 can activate the transcription of S100A4 via CX3CR1/MyD88/NF-κB signaling pathway in Cx3cr1^(+)Ccr2^(+)*** of METTL14 or GLS2,or interfering with this signal transduction pathway such as inhibiting MyD88 could ameliorate liver injuries and *** together,these findings indicate potential therapies for the treatment of MAFLD progression.

关键词： S100A4 MyD88 metabolism

Alterations in Serum Lipids and Lipoproteins Induced by Neoadjuvant Chemotherapy in Patients with Osteosarcoma around the Knee Joint:A Retrospective Analysis

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Current Medical Science 2024年第4期44卷 741-747页

作者： Su-guo WANG Yong-gang WANG Guo-wei QIAN Li-na TANG Xin ZHOU Dong-dong CHENG Chen-liang ZHOU Qing-cheng yang zan SHEN Gao-zhong HUANG Hong-tao LI Department of General Medicine Shenzhen Third People's HospitalShenzhen 518112China Department of VIP Clinic Shanghai Jiao Tong University Afiliated Sixth People's HospitalShanghai 200233China Department of Oncology Shanghai Jiao Tong University Affiliated Sixth People's HospitalShanghai 200233China Cancer Research Institute of Jilin University the First Hospital of Jilin UniversityChangchun 130021China Department of Orthopedics Shanghai Jiao Tong University Afiliated Sixth People's HospitalShanghai 200233China

Objective To investigate the serum lipid profiles of patients with localized osteosarcoma around the knee joint before and after neoadjuvant *** After retrospectively screening the data of 742 patients between January 2007 and July 2020,50 patients aged 13 to 39 years with Enneking stage II disease were included in the *** lipid levels,including total cholesterol(TC),triglycerides(TG),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C),lipoprotein-α[Lp(a)],and apolipoprotein A1,B,and E(ApoA1,ApoB,and ApoE),and clinicopathological characteristics were collected before and after neoadjuvant *** The mean levels of TC,TG,and ApoB were significantly increased following neoadjuvant chemotherapy(16%,38%,and 20%,respectively,*** values;P<0.01).The mean levels of LDL-C and ApoE were also 19%and 16%higher,respectively(P<0.05).No correlation was found between the pretreatment lipid profile and the histologic response to *** increase in Lp(a)was strongly correlated with the Ki-67 index(R=0.31,P=0.023).Moreover,a trend toward longer disease-free survival(DFS)was observed in patients with decreased TG and increased LDL-C following chemotherapy,although this difference was not statistically significant(P=0.23 and P=0.24,respectively).Conclusion Significant elevations in serum lipids were observed after neoadjuvant chemotherapy in patients with localized *** was no prognostic significance of pretreatment serum lipid levels on histologic response to neoadjuvant *** scale of increase in serum Lp(a)might have a potential prognostic role in *** with increased LDL-C or reduced TG after chemotherapy seem to exhibit a trend toward favorable DFS.

关键词： osteosarcoma neoadjuvant chemotherapy serum lipids

三维孔道结构(H_3NCH_2CH_2NH_3)_2(H_3NCH_2CH_2NH_2)[V~Ⅲ(H_2O)_2(V~ⅣO)_8(OH)_4(H(P,B)O_4)_4(P,B)O_4)_4(H_2O)_2]·3H_2O的水热合成及晶体化学研究——(1)水热合成与产物表征

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人工晶体学报 2005年第2期34卷 93-97页

作者：杨赞中廖立兵杜洪兵中国地质大学材料科学与工程学院人工晶体研究院北京100018

为了探讨化学成份对VPO体系孔道结构化合物结构稳定性的影响,根据酸碱平衡原理进行了合成实验设计;利用V2O5、H3PO4、H3BO3等简单的无机前驱物、乙二胺作结构导向剂,水热法合成了孔道结构钒硼磷酸盐化合物(H3NCH2CH2NH3)2(H3NCH2CH2NH2... 详细信息

为了探讨化学成份对VPO体系孔道结构化合物结构稳定性的影响,根据酸碱平衡原理进行了合成实验设计;利用V2O5、H3PO4、H3BO3等简单的无机前驱物、乙二胺作结构导向剂,水热法合成了孔道结构钒硼磷酸盐化合物(H3NCH2CH2NH3)2(H3NCH2CH2NH2)[VⅢ(H2O)2(VⅣO)8(OH)4(H(P,B)O4)4((P,B)O4)4(H2O)2]·3H2O(简称V9(P,B)8-en).典型的反应起始物摩尔比为n(V2O5):n(H3BO3):n(H3PO4):n(en):n(H2O)=0.89:3.50:3.50:3.60:265(pH值为6.5),在175℃、自生压力条件下恒温晶化6.5d(最终pH值为5.9).通过电子探针、粉末X射线衍射、红外吸收光谱、原子占位度修正等方法,对产物的化学成份、物相及其结构等进行了实验研究.证实V9(P,B)8-en为V9P8-en的类质同象化合物,不同晶粒中B与P的含量有差别,B与P之比为O.1:7.9～2.54:5.46(原子比),但恒有V:(P+B)≈9:8.表明通过合理设计和控制合成条件,可在保持V9P8-en基本结构不变的前提下通过同晶取代引入新的化学成份,并由此探讨成份与结构稳定性的关系.

关键词：孔道结构 NH3 H3PO4 VPO 结构导向剂 V2O5 产物 OH 原子水热合成