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Burden and outcome of human influenza in a tertiary care hospital of Bangladesh

Asian Pacific Journal of Tropical Medicine 2011年第6期4卷 478-481页

作者： Rasul CH Bakar MA Mamun AA Siraz MS zaman ru Department of Paediatrics Khulna Medical College & HospitalKhulnaBangladesh Department of Medicine Khulna Medical College & HospitalKhulnaBangladesh International Center for Diarrhoeal Disease Research Bangladesh

Objective:To determine the magnitude and outcome of influenza in southern part of Bangladesh and also to identify intrusion of novel influenza ***:This study was conducted for two years(2008-2009) in outpatient and inpatient department of both paediatrics and medicine discipline of Khulna Medical College *** and throat swab specimens were collected from each influenza like illness(ILI) case and kept together in a virus transport media and transported to international centre for diarrhoeal disease and research,Bangladesh laboratory. Influenza virus was detected by rRT-PCR including types and ***:A total of 526 patients were enrolled during the study period with the mean(SD) age of 19(17) years. Identification of influenza virus was 14%and positive cases were mostly found in under-five children(24%).The vast majority(88%) of influenza cases were found during April to September. Virus detection rate was higher in inpatient department(IPD)(21%) than in outpatient department (12%).The dominant virus type and subtype was influenza A(87%) and H3(49%),respectively. Type A was significantly higher than type B in causing severe illness compared to ILI(0R=7.04, 95%CI:2.76-18.7,P<0.01).Headache and chest indrawing was found in significantly higher proportion(P<0.05) in influenza positive IPD *** 31 hospitalized cases majority(77%) recovered completely except two cases that needed referral for additional ***: Influenza mostly affected under-five children and young *** peak season here was late summer and rainy season.

关键词： Influenza Burden Outcome Bangladesh

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