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PTEN as a Novel Diagnostic and Prognostic Biomarker of Head and Neck Squamous Cell Carcinoma

Proceedings of Anticancer Research 2024年第4期8卷 75-86页

作者： zain.ali Akbar ali Nishtar Medical College Pakistan

This review article explores phosphatase and tensin homolog(PTEN)’s role in head and neck squamous cell carcinoma(HNSCC)through comprehensive expression and methylation examinations,genetic mutation investigation,and prognostic *** the UALCAN informational collection,PTEN expression examination uncovered a critical over-expression in HNSCC cells isolated from normal control samples,proposing its role in HNSCC ***,analysis of PTEN expression across various clinical limits has shown critical up-regulation in different cancer development stages,racial groups,gender,and age classes within the context of HNSCC patients,suggesting its major role in cancer *** expression was validated by utilizing the GEPIA2.0 online tool,which showed PTEN expression was particularly significantly expressed in HNSCC cancer improvement when it appeared differently from normal control ***,examining PTEN validation across different phases of cancer advancement showed dysregulation in each of the four phases with the most raised expression in stage I and the least expression in stage ***,this study investigated the promoter methylation level of PTEN,figuring out a basic relationship between HNSCC samples and normal control *** promoter methylation across various clinical limits uncovered massive variations,with specific methylation patterns seen across malignant growth stages,race groups,gender,and age *** survival and disease-free survival(OS and DFS)utilizing the KM plotter tool showed a critical relationship between PTEN expression levels in HNSCC patients,showing high PTEN expression exhibited good overall survival when showed up distinctively comparable to low PTEN expression *** addition,in disease-free survival(DFS)evaluation HNSCC patients showing low PTEN expression experienced great DFS relative to HNSCC patients with high PTEN ***,to validate PTEN expression against surviv

关键词： Head and neck squamous cell carcinoma Diagnosis Treatment Biomarker

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A Review and Bibliometric Analysis of the Current Studies for the 6G Networks

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Computer Modeling in Engineering & Sciences 2024年第9期140卷 2165-2206页

作者： Qusay M.Salih Md.Arafatur Rahman Ahmad Firdaus Mohammed Rajih Jassim Hasan Kahtan Jasni Mohamad zain Ahmed Hussein ali Faculty of Computing Universiti Malaysia Pahang Al-Sultan Abdullah(UMPSA)PekanPahang26600Malaysia Department of Medical Equipment Technology Engineering Al Salam University CollegeBaghdadIraq School of Mathematics and Computer Science University of WolverhamptonWolverhampton01902UK Department of Production Engineering and Metallurgy University of TechnologyBaghdadIraq Cardiff School of Technologies Cardiff Metropolitan UniversityCardiffCF52YBUK Institute for Big Data Analytics and Artificial Intelligence(IBDAAI) Kompleks Al-KhawarizmiUniversiti Teknologi MARAShah AlamSelangor40450Malaysia Department Computer Science Al-Salam University CollegeBaghdadIraq

The race to develop the next generation of wireless networks,known as Sixth Generation(6G)wireless,which will be operational in 2030,has already *** realize its full potential over the next decade,6G will undoubtedly necessitate additional improvements that integrate existing solutions with cutting-edge ***,the studies about 6G are mainly limited and scattered,whereas no bibliometric study covers the 6G ***,this study aims to review,examine,and summarize existing studies and research activities in *** study has examined the Scopus database through a bibliometric analysis of more than 1,000 papers published between 2017 and ***,we applied the bibliometric analysis methods by including(1)document type,(2)subject area,(3)author,and(4)country of *** study’s results reflect the research 6G community’s trends,highlight important research challenges,and elucidate potential directions for future research in this interesting area.

关键词： 6G bibliometric wireless networks review

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Reinforcing the management of type 1 gastric esophageal varices

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World Journal of Gastroenterology 2024年第19期30卷 2615-2617页

作者： zain Majid Ghazi Abrar Department of Gastroenterology Sindh Institute of Urology and TransplantationKarachi 75500Pakistan

Variceal bleed represents an important complication of cirrhosis,with its presence reflecting the severity of liver *** varices,though less frequently seen than esophageal varices,present a distinct clinical challenge due to its higher intensity of bleeding and associated *** upon the Sarin classification,GOV1 is the most common subtype of gastric varices seen in clinical practice.

关键词： Gastric varices Sarin classification Gastroesophageal varices Cyanoacrylate Endoscopic variceal ligation Trans jugular intrahepatic portosystemic shunt

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Genuine entanglement under squeezed generalized amplitude damping channels with memory

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Chinese Physics B 2024年第2期33卷 158-163页

作者： Mazhar ali Department of Electrical Engineering Faculty of EngineeringIslamic University MadinahMadinah 107Saudi Arabia

We study genuine entanglement among three qubits undergoing a noisy process that includes dissipation, squeezing,and decoherence. We obtain a general solution and analyze the asymptotic quantum states. We find that most of these asymptotic states can be genuinely entangled depending upon the parameters of the channel, memory parameter, and the parameters of the initial states. We study Greenberger–Horne–Zeilinger(GHZ) states and W states, mixed with white noise,and determine the conditions for them to be genuinely entangled at infinity. We find that for these mixtures, it is possible to start with a bi-separable state(with a specific mixture of white noise) and end with genuine entangled states. However, the memory parameter μ must be very high. We find that in contrast to the two-qubit case, none of the three-qubit asymptotic states for n → ∞ are genuinely entangled.

关键词： genuine entanglement squeezed thermal baths multipartite states

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Re-analysis of temperature dependent neutron capture rates and stellarβ-decay rates of^(95-98)Mo

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Chinese Physics C 2024年第9期48卷 142-149页

作者： Abdul Kabir Jameel-Un Nabi Muhammad Tahir Abdul Muneem zain Ul Abideen Space and Astrophysics Research lab National Centre of GIS and Space ApplicationsDepartment of Space ScienceInstitute of Space TechnologyIslamabad 44000Pakistan University of Wah Quaid AvenueWah Cantt 47040PunjabPakistan Faculty of Engineering Sciences GIK Institute of Engineering Sciences and TechnologyTopi 23640Khyber PakhtunkhwaPakistan

The neutron capture rates and temperature dependent stellar beta decay rates of Mo isotopes are investigated within the framework of the statistical code TALYS v1.96 and the proton neutron quasi particle random phase approximation(pn-QRPA)*** Maxwellian average cross-section(MACS)and neutron capture rates for the^(95-98)Mo(n,γ)^(96-99)Mo radiative capture process are analyzed within the framework of the statistical code TALYS v1.96 based on the phenomenological nuclear level density model and gamma strength *** present model-based computations for the MACS are comparable to the existing measured *** sensitivity of stellar weak interaction rates to various densities and temperatures is investigated within the framework of the pn-QRPA *** attention is paid to the impact of thermally filled excited states in the decaying nuclei(^(95-98)Mo)on electron emission and positron capture ***,we compare the neutron capture rates and stellar beta decay *** is found that neutron capture rates are higher than stellar beta decay rates at both lower and higher temperatures.

关键词： cross-section TALYS nuclear level density decay rates capture rates

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Heat transfer analysis in particle-laden flows using the immersed boundary method

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Particuology 2024年第7期90卷 394-403页

作者： ali Abbas Zaidi Department of Mechanical Engineering University of Manitoba75A Chancellors CircleWinnipegR3T 5V6Canada

This paper investigates an efficient immersed boundary method(IBM)for multiple-core CPU machines with local grid refinement for the calculation of heat transfer between fluids and finite-sized *** fluid momentum equations are solved by using the fractional step method,while the energy equation is solved by employing the second-order Adams-Bashforth *** efficient load balancing between the CPU cores,the coupling between particles and fluid is obtained by applying the body force in the fluid equations,which depends on the solid volume fraction of particles contained in each grid cell,and then by linearly interpolating the particle temperature and velocity on the fluid grid cell(in place of the delta function commonly used in literature).Several test cases from the literature are studied,and good agreement is observed between the simulation results and the ***,a scaling study on multiple core machines is performed,demonstrating the proposed IBM's capabilities for a significant reduction in processing time.

关键词： Heat transfer Immersed boundary method Particle resolved direct numerical simulations Fluid solid interactions

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Simulation of the deformable lateral boundaries in biaxial test using DEM

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Particuology 2024年第5期88卷 161-175页

作者： ali Momeni Barry Clarke Yong Sheng ali Hassanpour WSP 3 Wellington PlaceLeedsLS1 4APUK Hull University HullHU6 7RXUK School of Civil Engineering University of LeedsLeedsLS2 9JTUK School of Computer Science University of HullHullHU6 7RXUK School of Chemical and Process Engineering University of LeedsLeedsLS2 9JTUK

Applying the discrete element method(DEM)in soil mechanics can provide abundant information at the particle-scale and facilitates illustration of the macro-mechanical behaviour of soils based on the inter-particle *** triaxial test is one of the most common laboratory methods to study the macro-mechanical behaviour of particulate materials such as ***,many problems in geotechnical design can be assumed and simplified as a plane strain *** a biaxial test can be conducted to reproduce the macro-mechanical behaviour of soil,where the sample is enclosed by two horizontal rigid platens and a vertical latex membrane,which is a deformable continuous element and allows the enclosed specimen to deform freely while maintaining confining stress during *** paper presents an algorithm to represent physical and mechanical characteristics of latex membrane in the 2D DEM simulation of biaxial test using the PFC^(2D) *** investigate the impact of the lateral boundary conditions on the micro-macro mechanical behaviours of soil samples,two sets of DEM biaxial tests are conducted,*** rigid and deformable lateral boundary *** DEM modeling results indicate that the lateral boundary conditions have a significant effect on the micro-scale fabric properties,thickness and inclination of the shear *** comparison between these two simulations also demonstrates that the lateral boundary conditions play a major role in the peak and post-peak stress-strain behaviours as well as the dilation and critical state behaviours of granular soils.

关键词： Discrete element method Biaxial test Deformable boundaries Shear band Critical state Fabric anisotropy Geometrical stability index

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Sensing the heavy water concentration in an H_(2)O-D_(2)O mixture by solid-solid phononic crystals

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Chinese Physics B 2024年第4期33卷 493-498页

作者： Mohammadreza Rahimi ali Bahrami Optoelectronic and Nanophotonics Research Laboratory(ONRL) Faculty of Electrical EngineeringSahand University of TechnologyTabrizIran

A new method based on phononic crystals is presented to detect the concentration of heavy water(D_(2)O)in an H_(2)O-D_(2)O *** have been obtained and analyzed in the concentration range of 0%-10%and 90%-100%D_(2)O.A proposed structure of tungsten scatterers in an aluminum host is *** order to detect the target material,a cavity region is considered as a sound wave resonator in which the target material with different concentrations of D_(2)O is *** changing the concentration of D_(2)O in the H_(2)O-D_(2)O mixture,the resonance frequency undergoes a frequency *** 1%change in D_(2)O concentration in the H_(2)O-D_(2)O mixture causes a frequency change of about 120 *** finite element method is used as the numerical method to calculate and analyze the natural frequencies and transmission spectra of the proposed *** performance evaluation index shows a high Q factor up to 1475758 and a high sensitivity up to 13075,which are acceptable values for sensing *** other figures of merit related to the detection performance also indicate high-quality performance of the designed sensor.

关键词： phononic crystals sensor H_(2)O-D_(2)O mixture cavity

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Note on Lower Triassic Gondolelloid Conodont Rediversifications with Emphasis on the Spathian Recovery

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Journal of Earth Science 2024年第4期35卷 1236-1242页

作者： ali Murat Kilic Department of Geological Engineering Faculty of EngineeringBalikesir UniversityBalikesir99100Turkey

Conodonts,as a biotic group,next to ammonoids,pollen and spores,crustaceans and vertebrates,provide proxy clues for environment and age assessments of the rocks in which they *** are widely used for Triassic marine ***,there are various discussions about their multielement taxonomy and evolutionary lineages(e.g.,generation,speciation).Although first studies reported that most Triassic conodont species were unimembrate,studies carried out in the following years maintained that all Triassic conodonts were *** statistical reconstructions of a number of Triassic apparatuses were attempted,the discovery of fused clusters and natural assemblages has subsequently demonstrated that Triassic conodonts are indeed multimembrate,and all of the elements exist together in the same *** present paper aims to clarify the evolutionary relationship and array of some Lower Triassic *** dagisi *** described.

关键词： Triassic Spathian conodont Columbitella Siberia environmental geology

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Experimental Study on Heat Storage Properties Comparison of Paraffin/Metal Foams Phase Change Material Composites

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Journal of Thermal Science 2024年第2期33卷 469-478页

作者： Waqar AHMED Abid HUSSAIN Hanzla SHAHID Imran ali Hafiz Muhammad ali Department of Mechanical Engineering University of Engineering and TechnologyTaxila47080Pakistan Department of Mechanical Engineering Institute of Space TechnologyIslamabadPakistan Department of Mechanical Mechatronics and Manufacturing EngineeringUniversity of Engineering and Technology LahoreFaisalabad CampusPunjabPakistan Mechanical Engineering Department King Fahd University of Petroleum and MineralsDhahran31261Saudi Arabia Interdisciplinary Research Center for Renewable Energy and Power Systems(IRC-REPS) King Fahd University of Petroleum and MineralsDhahran31261Saudi Arabia

Heat storage properties of phase change materials(PCMs) are essential characteristics that perform a key role in thermal heat energy storage *** thermal properties of PCMs can be improved by developing metal foam/PCM *** addition of metal foam in PCMs has a significant effect on the thermal characteristics of *** this paper,the heat storage properties of two different metal foam/PCM composites were experimentally *** behavior of paraffin in metal foam(copper and iron-nickel)/paraffin composites concerning pure paraffin at a constant heat flux of 1000 W/m^(2) in three directions simultaneously(x,y,and z) was *** was infiltrated into copper and iron-nickel foams to develop composite materials which resulted in enhancing the thermal conductivity of the paraffin.A comparative analysis is made on the heat storage properties of paraffin in copper and iron-nickel foams/paraffin *** temperature distribution during the phase transition process is experimentally *** comparison indicates that temperature uniformity in copper foam/paraffin composite is better than in iron-nickel foam/paraffin composite and pure paraffin at the same heat *** results show that at heat flux of 1000 W/m^(2),the heat storage time for copper foam/paraffin composite is 20.63% of that of iron-nickel foam/paraffin composite.

关键词： heat storage capacity paraffin/metal foam composite temperature uniformity heat storage rate phase transition process

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