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揿针联合艾盐包热熨治疗产后尿潴留临床研究

新中医 2024年第15期56卷 167-172页

作者：邹赛赛王晓蕾郑美凤温州医科大学附属第二医院产科浙江温州325000

目的:观察揿针联合艾盐包热熨治疗产后尿潴留的疗效。方法:选取120例阴道分娩后出现产后尿潴留的产妇,按随机数字表法分为西医组、揿针组、中医组各40例。西医组采用西药治疗,揿针组采用揿针治疗,中医组采用揿针联合艾盐包热熨治疗。比... 详细信息

目的:观察揿针联合艾盐包热熨治疗产后尿潴留的疗效。方法:选取120例阴道分娩后出现产后尿潴留的产妇,按随机数字表法分为西医组、揿针组、中医组各40例。西医组采用西药治疗,揿针组采用揿针治疗,中医组采用揿针联合艾盐包热熨治疗。比较3组临床疗效、不良反应发生情况以及首次排尿恢复时间、住院天数,比较3组治疗前后残余尿量、抑郁评分、焦虑评分、症状评分的变化。结果:中医组临床疗效总有效率为97.50%,高于西医组与揿针组,差异有统计学意义(P0.05)。结论:揿针联合艾盐包热熨治疗产后尿潴留能增强协同疗效,缩短产妇的首次排尿时间和住院周期,降低膀胱残余尿量,缓解抑郁、焦虑心理,改善临床症状,安全性较高。

关键词：产后尿潴留揿针艾盐包热熨抑郁评分焦虑评分症状评分

Hypoxia-preconditioned bone marrow-derived mesenchymal stem cells protect neurons from cardiac arrest-induced pyroptosis

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Neural Regeneration Research 2025年第4期20卷 1103-1123页

作者： Xiahong Tang Nan zheng Qingming Lin Yan You zheng Gong Yangping Zhuang Jiali Wu Yu Wang Hanlin Huang Jun Ke Feng Chen Shengli Clinical Medical College of Fujian Medical University Fujian Medical UniversityFuzhouFujian ProvinceChina Department of Emergency Fujian Provincial HospitalFuzhouFujian ProvinceChina Fujian Provincial Key Laboratory of Emergency Medicine FuzhouFujian ProvinceChina The Second Department of Intensive Care Unit Fujian Provincial Hospital South BranchFuzhouFujian ProvinceChina

Cardiac arrest can lead to severe neurological impairment as a result of inflammation,mitochondrial dysfunction,and post-cardiopulmonary resuscitation neurological *** preconditioning has been shown to improve migration and survival of bone marrow–derived mesenchymal stem cells and reduce pyroptosis after cardiac arrest,but the specific mechanisms by which hypoxia-preconditioned bone marrow–derived mesenchymal stem cells protect against brain injury after cardiac arrest are *** this end,we established an in vitro co-culture model of bone marrow–derived mesenchymal stem cells and oxygen–glucose deprived primary neurons and found that hypoxic preconditioning enhanced the protective effect of bone marrow stromal stem cells against neuronal pyroptosis,possibly through inhibition of the MAPK and nuclear factor κB ***,we transplanted hypoxia-preconditioned bone marrow–derived mesenchymal stem cells into the lateral ventricle after the return of spontaneous circulation in an 8-minute cardiac arrest rat model induced by *** results showed that hypoxia-preconditioned bone marrow–derived mesenchymal stem cells significantly reduced cardiac arrest–induced neuronal pyroptosis,oxidative stress,and mitochondrial damage,whereas knockdown of the liver isoform of phosphofructokinase in bone marrow–derived mesenchymal stem cells inhibited these *** conclude,hypoxia-preconditioned bone marrow–derived mesenchymal stem cells offer a promising therapeutic approach for neuronal injury following cardiac arrest,and their beneficial effects are potentially associated with increased expression of the liver isoform of phosphofructokinase following hypoxic preconditioning.

关键词： bone marrow–derived mesenchymal stem cells cardiac arrest cardiac resuscitation hypoxic preconditioning liver isoform of phosphofructokinase mitochondria neuroinflammation oxidative stress pyroptosis reactive oxygen species

Optimizing the key parameter to accelerate the recovery of AMOC under a rapid increase of greenhouse gas forcing

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 39-45页

作者： Haolan Ren Fei zheng Tingwei Cao Qiang Wang International Center for Climate and Environment Science(ICCES) Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina University of Chinese Academy of Sciences BeijingChina College of Oceanography Hohai UniversityNanjingChina CAS Key Laboratory of Ocean Circulation and Waves Institute of OceanologyChinese Academy of Sciences and Pilot National Laboratory for Marine Science and Technology(Qingdao)QingdaoChina

Atlantic Meridional Overturning Circulation(AMOC)plays a central role in long-term climate variations through its heat and freshwater transports,which can collapse under a rapid increase of greenhouse gas forcing in climate *** studies have suggested that the deviation of model parameters is one of the major factors in inducing inaccurate AMOC *** this work,with a low-resolution earth system model,the authors try to explore whether a reasonable adjustment of the key model parameter can help to re-establish the AMOC after its *** a new optimization strategy,the extra freshwater flux(FWF)parameter is determined to be the dominant one affecting the AMOC’s *** traditional ensemble optimal interpolation(EnOI)data assimilation and new machine learning methods are adopted to optimize the FWF parameter in an abrupt 4×CO_(2) forcing experiment to improve the adaptability of model parameters and accelerate the recovery of *** results show that,under an abrupt 4×CO_(2) forcing in millennial simulations,the AMOC will first collapse and then re-establish by the default FWF parameter ***,during the parameter adjustment process,the saltier and colder sea water over the North Atlantic region are the dominant factors in usefully improving the adaptability of the FWF parameter and accelerating the recovery of AMOC,according to their physical relationship with FWF on the interdecadal timescale.

关键词： Recovery of AMOC 4×CO_(2)forcing Key parameter Parameter estimation Data assimilation Machine learning

Mechanism by which Rab5 promotes regeneration and functional recovery of zebrafish Mauthner axons

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Neural Regeneration Research 2025年第6期20卷 1816-1824页

作者： Jiantao Cui Yueru Shen zheng Song Dinggang Fan Bing Hu Center for Advanced Interdisciplinary Science and Biomedicine of IHM Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina

Rab5 is a GTPase protein that is involved in intracellular membrane trafficking. It functions by binding to various effector proteins and regulating cellular responses, including the formation of transport vesicles and their fusion with the cellular membrane. Rab5 has been reported to play an important role in the development of the zebrafish embryo;however, its role in axonal regeneration in the central nervous system remains unclear. In this study, we established a zebrafish Mauthner cell model of axonal injury using single-cell electroporation and two-photon axotomy techniques. We found that overexpression of Rab5 in single Mauthner cells promoted marked axonal regeneration and increased the number of intra-axonal transport vesicles. In contrast, treatment of zebrafish larvae with the Rab kinase inhibitor CID-1067700markedly inhibited axonal regeneration in Mauthner cells. We also found that Rab5 activated phosphatidylinositol 3-kinase(PI3K) during axonal repair of Mauthner cells and promoted the recovery of zebrafish locomotor function. Additionally, rapamycin, an inhibitor of the mechanistic target of rapamycin downstream of PI3K, markedly hindered axonal regeneration. These findings suggest that Rab5 promotes the axonal regeneration of injured zebrafish Mauthner cells by activating the PI3K signaling pathway.

关键词： axonal regeneration Mauthner cell nerve regeneration Rab5 zebrafish

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郑美凤教授针灸治疗失眠临证经验

中国民族民间医药 2019年第13期28卷 76-78页

作者：柳伟婷张亮平郑美凤福建中医药大学

分析失眠的病因病机、临床表现,介绍郑美凤教授运用针灸治疗失眠的经验.郑教授认为失眠常涉及多脏腑,临床上应辨证论治,以耳穴配合体针、艾灸治疗,加以心理疏导,可获佳效.

关键词：失眠针灸经验郑美凤

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非专业班设置针灸学课程的现状与展望

中国中医药现代远程教育 2014年第3期12卷 72-74页

作者：何芙蓉郑美凤纪峰陈采益福建中医药大学针灸学院福州350122

针对我校非专业班《针灸学》课程的设置情况,通过自行设计的问卷调查,从学生层面了解该课程设置上存在的问题,主要包括课程定位、技能培养、再学习能力等,并在此基础上提出优化《针灸学》课程设置的改革思路和对策。

关键词：课程设置针灸学教学

Luminescence: a new perspective for investigating perovskite precursors

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Science China Materials 2025年第01期 312-313页

作者： Haofeng zheng Shaocong Hou School of Electrical Engineering and Automation Wuhan University Wuhan University Shenzhen Research Institute

In the past two decades, perovskite materials have made significant progress in optoelectronic semiconductors, emerging as formidable candidates for the next generation of commercial solar cells, light-emitting diodes (LEDs), and *** the fundamental solution chemistry and photophysics in solution-processed perovskite devices is crucial for comprehending to achieve highly efficient optoelectronic devices.

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Impact of Bubbles on Mechanical Performances in a Borosilicate Glass

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 25-29页

作者： LI Chengxing LI Dongfeng MA Shilong QIAO Ang zheng Qingshuang China Helicopter Research and Development Institute Jingdezhen 333001China State Key Laboratory of Silicate Materials for Ar-chitectures Wuhan University of TechnologyWuhan 430070China

To analyze the impact of bubbles on the mechanical behavior of glasses,by controlling the refining time,we prepared three borosilicate glasses with the same composition and different *** the analysis software integrated within the optical microscope,the diameter and number of the bubbles on the surface of three borosilicate glasses were *** the hardness and crack initiation resistance(CR),we built the relationship between the porosity and the mechanical performance of these borosilicate glasses.

关键词： bubbles oxide glass hardness creak initiation resistance

Role of iron ore in enhancing gasification of iron coke:Structural evolution,influence mechanism and kinetic analysis

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 58-69页

作者： Jie Wang Wei Wang Xuheng Chen Junfang Bao Qiuyue Hao Heng zheng Runsheng Xu School of Chemistry and Materials Science Hubei Engineering UniversityXiaogan 432000China Key Laboratory for Ferrous Metallurgy and Resources Utilization of Ministry of Education Wuhan University of Science and TechnologyWuhan 430081China Institue of Ironmaking Technology Baosteel Central Research InstituteShanghai 201999China State Key Laboratory of Advanced Metallurgy University of Science and Technology BeijingBeijing 100083China

The utilization of iron coke provides a green pathway for low-carbon *** uncover the influence mechanism of iron ore on the behavior and kinetics of iron coke gasification,the effect of iron ore on the microstructure of iron coke was ***,a comparative study of the gasification reactions between iron coke and coke was conducted through non-isothermal thermogravimetric *** findings indicate that compared to coke,iron coke exhibits an augmentation in micropores and specific surface area,and the micropores further extend and *** provides more adsorption sites for CO_(2) molecules during the gasification process,resulting in a reduction in the initial gasification temperature of iron *** the heating rate in non-isothermal gasification can enhance the reactivity of iron *** metallic iron reduced from iron ore is embedded in the carbon matrix,reducing the orderliness of the carbon structure,which is primarily responsible for the heightened reactivity of the carbon *** kinetic study indicates that the random pore model can effectively represent the gasification process of iron coke due to its rich pore ***,as the proportion of iron ore increases,the activation energy for the carbon gasification gradually decreases,from 246.2 kJ/mol for coke to 192.5 kJ/mol for iron coke 15wt%.

关键词： low-carbon ironmaking iron coke gasification structural evolution kinetic model