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American Journal of Plant Sciences 2024年第2期15卷 122-138页

作者： Mahmoud H. Ghozlan Nikita Gambhir Eman EL-Argawy Serkan Tokgöz Dilip K. Lakshman Amitava Mitra University of Nebraska Lincoln NE USA USDA-ARS Beltsville MD USA

The original online version of this article (Ghozlan, M.H., EL-Argawy, E., Tokgöz, S., Lakshman, D.K. and Mitra, A. (2020) Plant Defense against Necrotrophic Pathogens. American Journal of Plant Sciences, 11, 2122-2138. https://***/10.4236/ajps.2020.1112149) was published mistakenly without another co-author, Nikita Gambhir. In this regard, we revise authors and “how to cite” sections by adding her name.

关键词： Effectors Host Immunity Signaling P/MAMP ETI Disease Resistance

Polyethylene glycol has immunoprotective effects on sciatic allografts, but behavioral recovery and graft tolerance require neurorrhaphy and axonal fusion

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Neural Regeneration Research 2025年第4期20卷 1192-1206页

作者： Tyler A.Smith Liwen zhou Cameron L.Ghergherehchi Michelle Mikesh Cathy z.Yang Haley O.Tucker JuliAnne Allgood Jared S.Bushman George D.Bittner Department of Molecular Biosciences University of Texas at AustinAustinTXUSA Department of Neuroscience University of Texas at AustinAustinTXUSA Division of Pharmaceutical Sciences University of WyomingLaramieWYUSA

Behavioral recovery using(viable)peripheral nerve allografts to repair ablation-type(segmental-loss)peripheral nerve injuries is delayed or poor due to slow and inaccurate axonal ***,such peripheral nerve allografts undergo immunological rejection by the host immune *** contrast,peripheral nerve injuries repaired by polyethylene glycol fusion of peripheral nerve allografts exhibit excellent behavioral recovery within weeks,reduced immune responses,and many axons do not undergo Wallerian *** relative contribution of neurorrhaphy and polyethylene glycol-fusion of axons versus the effects of polyethylene glycol per se was unknown prior to this *** hypothesized that polyethylene glycol might have some immune-protective effects,but polyethylene glycol-fusion was necessary to prevent Wallerian degeneration and functional/behavioral *** examined how polyethylene glycol solutions per se affect functional and behavioral recovery and peripheral nerve allograft morphological and immunological responses in the absence of polyethylene glycol-induced axonal ***-type sciatic nerve injuries in outbred Sprague–Dawley rats were repaired according to a modified protocol using the same solutions as polyethylene glycol-fused peripheral nerve allografts,but peripheral nerve allografts were loose-sutured(loose-sutured polyethylene glycol)with an intentional gap of 1–2 mm to prevent fusion by polyethylene glycol of peripheral nerve allograft axons with host *** to negative control peripheral nerve allografts not treated by polyethylene glycol and in contrast to polyethylene glycol-fused peripheral nerve allografts,animals with loose-sutured polyethylene glycol peripheral nerve allografts exhibited Wallerian degeneration for all axons and myelin degeneration by 7 days postoperatively and did not recover sciatic-mediated behavioral functions by 42 days *** morphological signs of rejection,such as col

关键词： allograft rejection axotomy macrophage myelin nerve repair polyethylene glycol(PEG) sciatic nerve T cell transplantation Wallerian degeneration

Propofol with Varied Functions: A Potential Therapeutic Opportunity for Postoperative Nausea, Vomiting and Pruritus—A Narrative Review

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Open Journal of Anesthesiology 2024年第2期14卷 13-24页

作者： Thomas W. Anabah Fidelis Bayor David z. Kolbila Terence Kunfire Dakurah Sylvanus Kampo Juventus B. ziem Anaesthesia Unit Habana Medical Services Tamale Ghana Department of Anaesthesiology Lawra Municipal Hospital Ghana Health Service Lawra Ghana Department of Obstetrics and Gynecology School of Medicine University for Development Studies Tamale Ghana Department of Anaesthesia and Intensive Care School of Medical Sciences C. K. Tedam University of Technology and Applied Sciences Navrongo Ghana Department of Medical Microbiology School of Medical Sciences C. K. Tedam University of Technology and Applied Sciences Navrongo Ghana

Background: Despite the advances in anesthetics and non-pharmacological techniques, the prevalence of postoperative nausea and vomiting in all patients remains high. It is one of the most common distressing symptoms that cause dissatisfaction among patients after anesthesia and surgery. A sub-hypnotic dose of propofol has been shown to reduce morphine-induced postoperative nausea, vomiting, and pruritus. This review article will provide sufficient knowledge on the role of propofol in minimizing opioid-induced postoperative nausea, vomiting, and pruritus by providing detailed information on propofol antiemetic and antipruritic effects, as well as discussions based on empirically available data. Method: We conducted a narrative review of the literature published between 1990 and 2023 from a range of databases;PubMed, BioMed Central, Biosis Previews, Nature, International Pharmaceutical Abstracts, Springer-Link, and Elsevier. Discussion and Conclusion: The literatures reviewed in this study have demonstrated that propofol may have diverse therapeutic effects including antiemetic and antipruritic. The antiemetic effect of propofol may be an effective therapeutic approach for the prevention of postoperative nausea and vomiting. The literature also demonstrated that the use of propofol for sedation during surgery may as well ameliorates opioids induced postoperative pruritus, which may be beneficial to surgical patients. Also, it was demonstrated that prophylactic use of propofol may be an effective way of preventing nausea and vomiting and pruritus during opioid use.

关键词： Propofol Nausea Vomiting Antiemetic Antipruritic Surgery

家禽红螨(鸡皮刺螨)的杀螨剂抗药性及其管理方法

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养禽与禽病防治 2024年第2期 18-28页

作者： R.z.Abbas D.D.Colwell z.Iqbal A.Khan 刘红(校对) Department of Parasitology University of AgricultureFaisalabad-38040Pakistan Livestock Parasitology Agriculture and Agri-Food CanadaLethbridge Research Centre54031st Ave.S.LethbridgeAB.T1J 4B1Canada Department of Pathology University of AgricultureFaisalabad-38040Pakistan 默沙东动物保健品(上海)有限公司

家禽红螨(鸡皮刺螨)是一种危害养鸡业的吸血害虫,是世界许多地方家禽生产中的重要问题。尽管免疫学、生物技术和遗传学方法取得了进展,但控制家禽红螨却通常仍依赖于合成杀螨剂。随着这些化合物的反复长期使用导致了家禽螨虫抗药性种群... 详细信息

家禽红螨(鸡皮刺螨)是一种危害养鸡业的吸血害虫,是世界许多地方家禽生产中的重要问题。尽管免疫学、生物技术和遗传学方法取得了进展,但控制家禽红螨却通常仍依赖于合成杀螨剂。随着这些化合物的反复长期使用导致了家禽螨虫抗药性种群的形成,可用的有效杀螨剂正在迅速减少。因此需要不断研制新型的化学杀螨剂来取代旧的杀螨剂,但新型杀螨剂的开发和注册是一个漫长且昂贵的过程,故保持和维持现有杀螨剂的有效性至关重要。本综述分为2部分:第一部分提供了对鸡皮刺螨杀螨剂抗药性的基本认识;第二部分提供了关于保持现有杀螨剂有效性的抗药性管理的详细信息。

关键词：家禽红螨杀螨剂杀螨剂抗药性抗药性管理

含水杨酸和辛酰水杨酸的面部精华和面膜改善痤疮症状的有效性和安全性评价:一项随机对照试验

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中华皮肤科杂志 2024年第1期57卷 90-91页

作者：古丽孜巴·图尔荪屈园园新疆医科大学研究生院，乌鲁木齐 830001 新疆维吾尔自治区人民医院皮肤性病科新疆皮肤病临床医学研究中心新疆皮肤病研究重点实验室（XJYS1707），乌鲁木齐 830001

寻常痤疮临床上多表现为脓疱、丘疹、开放性和闭合性粉刺等炎性和非炎性皮损,其病理过程涉及皮脂腺的异常调节和皮脂成分紊乱等多个环节.轻度痤疮患者可出现皮肤屏障功能损伤、皮肤含水量下降、皮脂分泌增加.此外,炎症后红斑(PIE)和炎... 详细信息

寻常痤疮临床上多表现为脓疱、丘疹、开放性和闭合性粉刺等炎性和非炎性皮损,其病理过程涉及皮脂腺的异常调节和皮脂成分紊乱等多个环节.轻度痤疮患者可出现皮肤屏障功能损伤、皮肤含水量下降、皮脂分泌增加.此外,炎症后红斑(PIE)和炎症后色素沉着(PIH)也显著影响患者生活质量.目前临床指南中已将外用维A酸、过氧化苯甲酰、壬二酸以及联用不同外用制剂、口服药物、物理与化学治疗纳入痤疮推荐治疗方案,但针对PIE和PIH的临床研究还比较有限,也缺乏联合应用护肤品的临床效果观察.

关键词：外用制剂寻常痤疮临床指南化学治疗过氧化苯甲酰皮肤屏障功能口服药物壬二酸

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人类排放情景的设计与全球变暖预估

气候变化研究进展 2024年第2期20卷 261-264页

作者：赵宗慈罗勇黄建斌清华大学地球系统科学系北京100084 中国气象局国家气候中心北京100081 中国科学院大学资源环境学院北京100049

1气候变化的原因全球气候变化除地球系统内部变率外,自然强迫和人为强迫是重要的外部驱动力。其中自然强迫包括太阳活动和火山活动。人为强迫即人类活动,包括大量化石燃料燃烧排放温室气体、土地利用,以及气溶胶与污染排放等,其强度取... 详细信息

1气候变化的原因全球气候变化除地球系统内部变率外,自然强迫和人为强迫是重要的外部驱动力。其中自然强迫包括太阳活动和火山活动。人为强迫即人类活动,包括大量化石燃料燃烧排放温室气体、土地利用,以及气溶胶与污染排放等,其强度取决于人口发展与变化、社会经济发展、技术变化及其内部的协调性等。本文重点给出人类强迫的影响。IPCC第六次评估报告明确表明,近百年特别是近几十年来观测到的全球变暖归因为人类活动的影响。

关键词：太阳活动火山活动排放情景全球变暖社会经济发展全球气候变化人类强迫变率

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岩石圈内榴辉岩的命运

中国科学：地球科学 2024年第3期54卷 897-901页

作者：王振胜徐义贤中国地质大学地质过程与矿产资源国家重点实验室武汉430074 浙江省地学大数据和地球深部资源重点实验室浙江大学地球科学学院杭州310058

1榴辉岩及其黏性排出的概念榴辉岩是由洋壳或陆壳岩石在俯冲、碰撞等构造埋深作用下,增压到1~1.5GPa以上,发生超高压变质作用(ultra-high pressure metamorphism)而生成的以石榴子石和绿辉石为主要矿物组成的特殊岩石类型.深源捕虏体研... 详细信息

1榴辉岩及其黏性排出的概念榴辉岩是由洋壳或陆壳岩石在俯冲、碰撞等构造埋深作用下,增压到1~1.5GPa以上,发生超高压变质作用(ultra-high pressure metamorphism)而生成的以石榴子石和绿辉石为主要矿物组成的特殊岩石类型.深源捕虏体研究表明克拉通岩石圈地幔中也存在一定量的榴辉岩,可能与早期俯冲或地幔柱活动有关(Aulbach和Smart, 2023).

关键词：超高压变质作用石榴子石绿辉石深源捕虏体榴辉岩岩石类型克拉通岩石圈地幔柱活动

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Impact of payment source, referral site, and place of residence on outcomes after allogeneic transplantation in Mexico

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World Journal of Transplantation 2024年第2期14卷 76-87页

作者： Andrés Gómez-De León Yesica A López-Mora Valeria García-zárate Ana Varela-Constantino Sergio U Villegas-De Leon Xitlaly J González-Leal Raúl del Toro-Mijares Anna C Rodríguez-zúñiga Juan F Barrios-Ruiz Victor Mingura-Ledezma Perla R Colunga-Pedraza Olga G Cantú-Rodríguez César H Gutiérrez-Aguirre Luz Tarín-Arzaga Elías E González-López David Gómez-Almaguer Hematology Service Universidad Autónoma de Nuevo LeónFacultad de Medicina y Hospital Universitario Dr.JoséEleuterio GonzálezMonterrey 64460Nuevo LeónMexico Hemato-logy Service Clínica Gómez AlmaguerMonterrey 64710Nuevo LeónMexico Hematology Service Instituto Tecnológico de Estudios Superiores de MonterreyTec SaludEscuela de Medicina Ignacio SantosMonterrey 64710Nuevo LeónMexico

BACKGROUND The impact of social determinants of health in allogeneic transplant recipients in low-and middle-income countries is poorly *** observational study analyzes the impact of place of residence,referring institution,and transplant cost coverage(out-of-pocket vs government-funded vs private insurance)on outcomes after allogeneic hematopoietic stem cell transplantation(alloHSCT)in two of Mexico's largest public and private *** To evaluate the impact of social determinants of health and their relationship with outcomes among allogeneic transplant recipients in *** In this retrospective cohort study,we included adolescents and adults≥16 years who received a matched sibling or haploidentical transplant from *** were selected without regard to their diagnosis and were sourced from both a private clinic and a public University Hospital in *** payment groups were compared:Out-of-pocket(OOP),private insurance,and a federal Universal healthcare program“Seguro Popular”.Outcomes were compared between referred and institution-diagnosed patients,and between residents of Nuevo Leon and *** outcomes included overall survival(OS),categorized by residence,referral,and payment *** outcomes encompassed early mortality,event-free-survival,graft-versus-host-relapse-free survival,and non-relapse-mortality(NRM).Statistical analyses employed appropriate tests,Kaplan-Meier method,and Cox proportional hazard regression *** software included SPSS and R with tidycmprsk *** Our primary outcome was overall *** included 287 patients,n=164 who lived out of state(57.1%),and n=129 referred from another institution(44.9%).The most frequent payment source was OOP(n=139,48.4%),followed by private insurance(n=75,26.1%)and universal coverage(n=73,25.4%).No differences in OS,event-free-survival,NRM,or graft-versus-host-relapse-free survival were observed for patients dia

关键词： Hematopoietic cell transplant Social determinants of health Geography Haploidentical Out-of-pocket Financial toxicity Survival Health services and outcomes Hematopoietic malignancy Aplastic anemia

Thermally Radiative Viscous Fluid Flow Over Curved Moving Surface in Darcy-Forchheimer Porous Space

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Communications in Theoretical Physics 2019年第3期71卷 259-266页

作者： A.Rauf z.Abbas S.A.Shehzad T.mushtaq Department of Mathematics The Islamia University of Bahawalpur Department of Mathematics COMSATS University Islamabad

A numerical analysis is developed for incompressible hydromagnetic viscous fluid passed through a curved stretching surface. Fluid saturated by porous space is bounded by curved surface. Term of porous medium is characterized by implementation of Darcy-Forchheimer theory. Adequate similarity variables are implemented to develop a system of non-linear ordinary differential system of equations, which govern the flow behavior. The impact of radiation constraint and Eckert number is incorporated in the energy equation. Numerical scheme based on RKF45 technique is implemented to solve the derived flow model. Prescribed heat flux(PHF) and prescribed surface temperature(PST) boundary conditions are utilized on temperature with Prescribed Surface Concentration(PSC) and Prescribed Mass Flux(PMF)on concentration. Flow behavior is discussed for both the slip and no-slip conditions. Dimensionless physical quantities are presented through graphs and tables.

关键词： viscous fluid porous medium curved stretching sheet radiation Joule heating

Cost-Effectiveness Analysis of Renalof® versus Extracorporeal Shockwave Lithotripsy (ESWL) for the Treatment of Kidney Stones ≤ 1 cm in Nicaragua

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Health 2024年第7期16卷 674-687页

作者： Mélida M. Aguilar Chamorro Sergio Vargas Collado Leslie Pérez Ruíz David Márquez Soriano Jorge Luis Soriano García Clínica Senior Managua Nicaragua Centro de Inmunología Molecular Havana Cuba Catalysis S.L. Madrid Spain

Objectives: To assess the efficiency in terms of cost-effectiveness (CE) of oral Renalof® treatment versus extracorporeal shockwave lithotripsy (ESWL) in the treatment of kidney stones ≤ 1 cm in Nicaragua. Methods: A cost-effectiveness economic evaluation was carried out based on the results obtained in the randomised, prospective, observational, single-blind, prospective, phase 2 clinical trial. Cost-effectiveness and the incremental cost-effectiveness ratio (ICER) were calculated. Economic data were obtained from the Economics Department of Clínica Senior in Managua, Nicaragua. The monetary cost was expressed in US dollars (USD). Results: Treatment with Renalof® yielded a CE of $1,323.08/% remission, while ESWL was $9,498.54/% remission. The ICER shows that, in order to achieve a high percentage of kidney stone remission with ESWL, an extra $4,734.70 per patient must be invested. Conclusions: The use of Renalof® is shown to be a more cost-effective option than ESWL. It is recommended for the treatment of kidney stones ≤ 1 cm in size.

关键词： Economic Evaluation Pharmacoeconomics Renalof® Extracorporeal Shockwave Lithotripsy Kidney Stones