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国际医学放射学杂志 2013年第3期 264-264页

作者： M.Li J.zhang J.Pan z.lu 丁静 Departments of Radiology and Cardiology Shanghai No.6 People’s HospitalSchool of MedicineShanghai Jiaotong University

目的通过CT冠状动脉成像来研究冠状动脉阻塞性疾病远端CT值反向递减(RAG)征象的临床价值。材料与方法本研究经过机构审查委员会批准,所有参与病人均签署书面知情同意书。在这项前瞻性研究中纳入连续的80例病人,年龄35～87岁,平均(67.1±... 详细信息

目的通过CT冠状动脉成像来研究冠状动脉阻塞性疾病远端CT值反向递减(RAG)征象的临床价值。材料与方法本研究经过机构审查委员会批准,所有参与病人均签署书面知情同意书。在这项前瞻性研究中纳入连续的80例病人,年龄35～87岁,平均(67.1±12.1)岁;其中男性62例,年龄35～86岁,平均(65.8±12.5)岁;女性18例,年龄58～87岁,平均(71.7±9.3)岁。RAG征象被定义为血管阻塞性病变远端管腔内反向的对比剂填充梯度,其表现为近端节段血管内CT值较低,而向远侧血管内CT值反而逐步增加。同时记录其他参数,如病变的长度和CT冠状动脉成像可见的桥血管。用Mann-Whitney秩和检验和Fisher精确检验进行统计学比较。结果共有94例阻塞性病变。介入性冠状动脉血管造影证实49例为慢性完全闭塞(CTO),45例部分闭塞(SO)。CTO组的RAG征象显著常见于SO组[65%(32/49)∶7%(3/45),P<0.001]。同样地,CT值梯度测量值[(5.1±13.4)HU/10mm∶(-13.4±68.7)HU/10mm,P<0.001]和病变长度[(23.6±22.7)mm∶(6±3)mm,P<0.001]两组间差异有统计学意义。在CT冠状动脉成像中仅有4例CTO观测到有侧支循环血管。在CT冠状动脉成像中所有具有RAG征象的血管,在介入性冠状动脉血管造影都显示有逆行的侧支循环血管供血。如结合所有这些参数来诊断CTO,敏感度和特异度分别为90%(44/49)和93%(42/45)。结论 RAG征象表明血管阻塞性病变远端存在逆行的侧支循环血流。这个征象对于诊断CTO具有高度特异性,并且有助于鉴别SO和CTO。

关键词：动脉阻塞性疾病 CTO 远端 CT 冠状动脉成像慢性完全闭塞征象

Post-rifting magmatism at the northern margin of the South China Sea:Evidenced by an ocean bottom seismometer experiment

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Earthquake Science 2025年第1期38卷 1-16页

作者： lu zhang Chen Cai Rui Gao School of Earth Sciences and Engineering Sun Yat-sen UniversityGuangzhou 510275China School of Geophysics and Geomatics China University of GeosciencesWuhan 430074China Southern Marine Science and Engineering Guangdong Laboratory(zhuhai) Zhuhai 519000China Guangdong Provincial Key Lab of Geodynamics and Geohazards Guangzhou 510275China Guangdong Deep Earth Exploration and Geological Process Technology Research Center Guangzhou 510275China Key Laboratory of Deep-Earth Dynamics of Ministry of Natural Resources Institute of GeologyChinese Academy of Geological SciencesBeijing 100037China

Magmatism at continental margins is of great significance in understanding the continental *** present a twodimensional P-wave velocity model derived from an ocean bottom seismometer experiment,conducted across the middle northern continental margin of the South China Sea(SCS).The detailed velocity structures reveal significant heterogeneities extending from the continental shelf to the continent-ocean transition *** crust exhibits its greatest thickness below the continental shelf,measuring~23 km and gradually thins to~13 km at the distal ***,a narrow and distinct continent-ocean transition with only 40-km width is *** also observe a high-velocity layer within the transition zone,reaching thickness of up to 4 km,characterized by P-wave velocities ranging from 7.0 km/s to 7.6 km/s in the lower *** on the syn-rift melt generation using decompression melting model,we ascertain that syn-rift magmatism cannot fully account for the observed thick high-velocity *** integrating findings from previous geophysical and geochemical studies presenting extensive volcanic edifice on the seafloor at the northern margin,as well as ocean-island-basalt-type magmaticsamples in the SCS area,we propose that post-rifting magmatism associated with the Hainan Plume may have influenced theformation of the high-velocity lower crust within the transition zone and the northern margin of the SCS can thus be recognizedas magma-poor type margin.

关键词： South China Sea continental margin seismic refraction post-rift magmatism

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Prioritization Hindsight Experience Based on Spatial Position Attention for Robots

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Machine Intelligence Research 2025年第1期22卷 160-175页

作者： Ye Yuan Yu Sha Feixiang Sun Haofan lu Shuiping Gou Jie luo China Nuclear Power Technology Research Institute Co. Ltd.Shenzhen518028China School of Artificial Intelligence Xidian UniversityXi’an710071China Suzhou Tianhe China Power International Engineering Technology Co. Ltd.Suzhou215000China

Sparse rewards pose significant challenges in deep reinforcement learning as agents struggle to learn from experiences with limited reward *** experience replay(HER)addresses this problem by creating“small goals”within a hierarchical decision ***,HER does not consider the value of different episodes for agent *** this paper,we propose SPAHER,a framework for prioritizing hindsight experiences based on spatial position *** allows the agent to prioritize more valuable experiences in a manipulation *** achieves this by calculating transition and trajectory spatial position functions to determine the value of each episode for experience *** evaluate SPAHER on eight robot manipulation tasks in the Fetch and Hand environments provided by OpenAI *** results show that our method improves the final mean success rate by an average of 3.63%compared to HER,especially in challenging Hand ***,these improvements are achieved without any increase in computation time.

关键词： Hindsight experience replay spatial position attention sparse reward deep reinforcement learning prioritization hindsight experience

In-situ synthesis of z-scheme CeO2@WO3 heterojunction with aromatic rings as electron medium for efficient photocatalytic degradation of perfluorobutane sulfonate

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Journal of Rare Earths 2025年第03期 470-479页

作者： Shihai Cao Haocheng Yang Cheng Cheng Jinheng Dai Shuaishuai lu Yao lu College of Environmental Engineering Nanjing Institute of Technology Jiangsu Environmental Engineering Technology Co. Ltd. Key Laboratory of Jiangsu Province for Chemical Pollution Control and Resources Reuse School of Environmental and Biological EngineeringNanjing University of Science and Technology School of Environment and Safety Engineering School of Emergency ManagementInstitute of Environment and EcologyJiangsu University Jiangsu Collaborative Innovation Ceater of Technology and Material of Water Treatment Suzhou University of Science and Technology

Photocatalytic technology has been proven to be a simple and effective method for degrading recalcitrant organic *** this study,a series of z-scheme heterojunction nanocomposites composed of CeO2and terephthalic acid-modified WO3was prepared and further used as photocatalysts for perfluorobutane sulfonate（PFBS） *** this design,terephthalic acid was used as an electron recombination center and heterojunction mediator,which effectively enhances the migration ability of electron-hole pairs and the physicochemical stability of the *** addition,in situ synthesis of CeO2onto the WO3surface by the coordinate bond between terephthalic acid and Ce ions can avoid *** a result,the CeO2@WO3photocatalyst exhibits excellent PFBS degradation ability（94%for CeO2@WO3vs.19% for CeO2）.After the fifth cyclic degradation experiment,the CeO2@WO3photocatalyst still maintains stable degradation ***,the reaction mechanism of the PFBS in CeO2@WO3photocatalytic process was analyzed by free radical trapping experiment and liquid chromatography tandem mass spectrometry（LC-MS） *** study provides new insights for constructing z-scheme heterojunction and demonstrates that CeO2@WO3photocatalysts possess a promising prospect for degrading PFBS pollutants.

关键词：

STCF conceptual design report (Volume 1): Physics & detector

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Frontiers of physics 2024年第1期19卷 1-154页

作者： M.Achasov X.C.Ai L.P.An R.Aliberti Q.An X.z.Bai Y.Bai O.Bakina A.Barnyakov V.Blinov V.Bobrovnikov D.Bodrov A.Bogomyagkov A.Bondar I.Boyko z.H.Bu F.M.Cai H.Cai J.J.Cao Q.H.Cao X.Cao z.Cao Q.Chang K.T.Chao D.Y.Chen H.Chen H.X.Chen J.F.Chen K.Chen L.L.Chen P.Chen S.L.Chen S.M.Chen S.Chen S.P.Chen W.Chen X.Chen X.F.Chen X.R.Chen Y.Chen Y.Q.Chen H.Y.Cheng J.Cheng S.Cheng T.G.Cheng J.P.Dai L.Y.Dai X.C.Dai D.Dedovich A.Denig I.Denisenko J.M.Dias D.z.Ding L.Y.Dong W.H.Dong V.Druzhinin D.S.Du Y.J.Du z.G.Du L.M.Duan D.Epifanov Y.L.Fan S.S.Fang z.J.Fang G.Fedotovich C.Q.Feng X.Feng Y.T.Feng J.L.Fu J.Gao Y.N.Gao P.S.Ge C.Q.Geng L.S.Geng A.Gilman L.Gong T.Gong B.Gou W.Gradl J.L.Gu A.Guevara L.C.Gui A.Q.Guo F.K.Guo J.C.Guo J.Guo Y.P.Guo z.H.Guo A.Guskov K.L.Han L.Han M.Han X.Q.Hao J.B.He S.Q.He X.G.He Y.L.He z.B.He z.X.Heng B.L.Hou T.J.Hou Y.R.Hou C.Y.Hu H.M.Hu K.Hu R.J.Hu W.H.Hu X.H.Hu Y.C.Hu J.Hua G.S.Huang J.S.Huang M.Huang Q.Y.Huang W.Q.Huang X.T.Huang X.J.Huang Y.B.Huang Y.S.Huang N.Hüsken V.Ivanov Q.P.Ji J.J.Jia S.Jia z.K.Jia H.B.Jiang J.Jiang S.z.Jiang J.B.Jiao z.Jiao H.J.Jing X.L.Kang X.S.Kang B.C.Ke M.Kenzie A.Khoukaz I.Koop E.Kravchenko A.Kuzmin Y.Lei E.Levichev C.H.Li C.Li D.Y.Li F.Li G.Li G.Li H.B.Li H.Li H.N.Li H.J.Li H.L.Li J.M.Li J.Li L.Li L.Li L.Y.Li N.Li P.R.Li R.H.Li S.Li T.Li W.J.Li X.Li X.H.Li X.Q.Li X.H.Li Y.Li Y.Y.Li z.J.Li H.Liang J.H.Liang Y.T.Liang G.R.Liao L.z.Liao Y.Liao C.X.Lin D.X.Lin X.S.Lin B.J.Liu C.W.Liu D.Liu F.Liu G.M.Liu H.B.Liu J.Liu J.J.Liu J.B.Liu K.Liu K.Y.Liu K.Liu L.Liu Q.Liu S.B.Liu T.Liu X.Liu Y.W.Liu Y.Liu Y.L.Liu z.Q.Liu z.Y.Liu z.W.Liu I.Logashenko Y.Long C.G.lu J.X.lu N.lu Q.F.Lü Y.lu Y.lu z.lu P.lukin F.J.luo T.luo X.F.luo Y.H.luo H.J.Lyu X.R.Lyu J.P.Ma P.Ma Y.Ma Y.M.Ma F.Maas S.Malde D.Matvienko z.X.Meng R.Mitchell A.Nefediev Y.Nefedov S.L.Olsen Q.Ouyang P.Pakhlov G.Pakhlova X.Pan Y.Pan E.Passemar Y.P.Pei H.P.Peng L.Peng X.Y.Peng X.J.Peng K.Peters S.Pivovarov E.Pyata B.B.Qi Y.Q.Qi W.B.Qian Y.Qian C.F.Qiao J.J.Qin J.J.Qin L.Q.Qin X.S.Qin T.L.Qiu J.Rademacker C.F.Redmer H.Y.Sang Anhui University Hefei 230039China Beihang University Beijing 100191China Budker Institute of Nuclear Physics Novosibirsk 630090Russia CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China Cavendish Laboratory University of CambridgeJJ Thomson AveCambridge CB30HEUnited Kingdom Central China Normal University Wuhan 430079China Central South University Changsha 410083China China University of Geosciences Wuhan 430074China China University of Mining and Technology Xuzhou 221116China École Polytechnique Fédérale de Lausanne(EPFL) LausanneSwitzerland Fudan University Shanghai 200433China Goethe University Frankfurt D-60325 Frankfurt am MainGermany Guangxi Normal University Guilin 541004China Guangxi Uninversity Nanning 530004China Hangzhou Institute for Advanced Study UCASHangzhou 310024China Hebei Normal University Shijiazhuang 050024China Hebei University Baoding 071002China Hefei University of Technology Hefei 230601China Helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University Kaifeng 475004China High Energy Physics Center Chung-Ang UniversitySeoul 06974Korea Higher School of Economy 11 Pokrovsky Bulvar Moscow 109028Russia Huangshan University Huangshan 245000China Hubei University of Automotive Technology Shiyan 442002China Hunan Normal University Changsha 410081China Hunan University of Science and Technology Xiangtan 411201China Hunan University Changsha 410082China Indiana University BloomingtonIndiana 47405USA Inner Mongolia University Hohhot 010021China Institute of Advanced Science Facilities Shenzhen 518107China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China Institute of Physics Academia SinicaTaipeiTaiwan 11529China Institute of Theoretical Physics Chinese Academy of SciencesBeijing 100190China Jilin University Changch

The superτ-charm facility(STCF)is an electron–positron collider proposed by the Chinese particle physics *** is designed to operate in a center-of-mass energy range from 2 to 7 GeV with a peak luminosity of 0.5×10^(35) cm^(–2)·s^(–1) or *** STCF will produce a data sample about a factor of 100 larger than that of the presentτ-charm factory—the BEPCII,providing a unique platform for exploring the asymmetry of matter-antimatter(charge-parity violation),in-depth studies of the internal structure of hadrons and the nature of non-perturbative strong interactions,as well as searching for exotic hadrons and physics beyond the Standard *** STCF project in China is under development with an extensive R&D *** document presents the physics opportunities at the STCF,describes conceptual designs of the STCF detector system,and discusses future plans for detector R&D and physics case studies.

关键词： electron–positron collider tau-charm region high luminosity STCF detector conceptual design

Storage time affects the level and diagnostic efficacy of plasma biomarkers for neurodegenerative diseases

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Neural Regeneration Research 2025年第8期20卷 2373-2381页

作者： Lifang zhao Mingkai zhang Qimeng Li Xuemin Wang Jie lu Ying Han Yanning Cai Department of Clinical Biobank Xuanwu HospitalCapital Medical UniversityBeijingChina Beijing Geriatric Medical Research Center BeijingChina Department of Neurology Xuanwu HospitalCapital Medical UniversityBeijingChina Department of Radiology and Nuclear Medicine Xuanwu HospitalCapital Medical UniversityBeijingChina Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics BeijingChina Key Laboratory of Neurodegenerative diseases Ministry of EducationBeijingChina School of Biomedical Engineering Hainan UniversityHaikouHainan ProvinceChina Center of Alzheimer’s Disease Beijing Institute for Brain DisordersBeijingChina National Clinical Research Center for Geriatric Diseases BeijingChina Institute of Biomedical Engineering Shenzhen Bay LaboratoryGaoke Innovation CenterShenzhenGuangdong ProvinceChina Department of Neurobiology Xuanwu HospitalCapital Medical UniversityBeijingChina

Several promising plasma biomarker proteins,such as amyloid-β(Aβ),tau,neurofilament light chain,and glial fibrillary acidic protein,are widely used for the diagnosis of neurodegenerative ***,little is known about the long-term stability of these biomarker proteins in plasma samples stored at-80°*** aimed to explore how storage time would affect the diagnostic accuracy of these biomarkers using a large *** samples from 229 cognitively unimpaired individuals,encompassing healthy controls and those experiencing subjective cognitive decline,as well as 99 patients with cognitive impairment,comprising those with mild cognitive impairment and dementia,were acquired from the Sino Longitudinal Study on Cognitive Decline *** samples were stored at-80°C for up to 6 years before being used in this *** results showed that plasma levels of Aβ42,Aβ40,neurofilament light chain,and glial fibrillary acidic protein were not significantly correlated with sample storage ***,the level of total tau showed a negative correlation with sample storage ***,in individuals without cognitive impairment,plasma levels of total protein and tau phosphorylated protein threonine 181(p-tau181)also showed a negative correlation with sample storage *** was not observed in individuals with cognitive ***,we speculate that the diagnostic accuracy of plasma p-tau181 and the p-tau181 to total tau ratio may be influenced by sample storage ***,caution is advised when using these plasma biomarkers for the identification of neurodegenerative diseases,such as Alzheimer's ***,in cohort studies,it is important to consider the impact of storage time on the overall results.

关键词： Alzheimer’s disease amyloid-β diagnostic ability glial fibrillary acidic protein neurodegeneration neurofilament light chain plasma biomarkers single molecule array storage time tau

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MR成像引导穿刺检测男性前列腺癌的成本效益

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国际医学放射学杂志 2017年第6期 724-724页

作者： S.Pahwa N.K.Schiltz L.E.Ponsky z.lu M.A.Griswold V.Gulani 刘会佳 Department of Radiology University Hospitals Case Medical Center

摘要目的评估多参数MR成像对临床怀疑前列腺癌病人经MRI引导穿刺活检术发现前列腺癌的价值。材料与方法对于直肠指诊结果异常或前列腺特异性抗原(PSA)升

关键词： MRI MR 穿刺活检成本效益前列腺癌

Ti_(3)C_(2)T_(x) Composite Aerogels Enable Pressure Sensors for Dialect Speech Recognition Assisted by Deep Learning

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Nano-Micro Letters 2025年第5期17卷 1-15页

作者： Yanan Xiao He Li Tianyi Gu Xiaoteng Jia Shixiang Sun Yong Liu Bin Wang He Tian Peng Sun Fangmeng Liu Geyu lu State Key Laboratory of Integrated Optoelectronics College of Electronic Science and EngineeringJilin UniversityChangchun 130012People’s Republic of China School of Integrated Circuits Tsinghua UniversityBeijing 100084People’s Republic of China International Center of Future Science Jilin UniversityChangchun 130012People’s Republic of China

Wearable pressure sensors capable of adhering comfortably to the skin hold great promise in sound ***,current intelligent speech assistants based on pressure sensors can only recognize standard languages,which hampers effective communication for non-standard language ***,we prepare an ultralight Ti_(3)C_(2)T_(x)MXene/chitosan/polyvinylidene difluoride composite aerogel with a detection range of 6.25 Pa-1200 k Pa,rapid response/recovery time,and low hysteresis(13.69%).The wearable aerogel pressure sensor can detect speech information through the throat muscle vibrations without any interference,allowing for accurate recognition of six dialects(96.2%accuracy)and seven different words(96.6%accuracy)with the assistance of convolutional neural *** work represents a significant step forward in silent speech recognition for human–machine interaction and physiological signal monitoring.

关键词： Pressure sensor Wearable sensor Ti_(3)C_(2)T_(x) composite aerogel Dialect speech recognition

[Three-dimensional human-robot mechanics modeling for dual-arm nursing-care robot transfer based on individualized musculoskeletal multibody dynamics]

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Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 2025年第1期42卷 96-104页

作者： zhiqiang Yang Funing Hou Qiang Lin Jiexin Xie Hao lu Shijie Guo Academy for Engineering and Technology Fudan University Shanghai 200433 P. R. China. General Hospital of North China Petroleum Administration Cangzhou Hebei 062552 P. R. China. College of Electronic Information and Automation Tianjin University of Science and Technology Tianjin 300457 P. R. China.

During transfer tasks, the dual-arm nursing-care robot require a human-robot mechanics model to determine the balance region to support the patient safely and stably. Previous studies utilized human-robot two-dimensional static equilibrium models, ignoring the human body volume and muscle torques, which decreased model accuracy and confined the robot ability to adjust the patient's posture in three-dimensional spatial. Therefore, this study proposes a three-dimensional spatial mechanics modeling method based on individualized human musculoskeletal multibody dynamics. Firstly, based on the mechanical features of dual-arm support, this study constructed a foundational three-dimensional human-robot mechanics model including body posture, contact position and body force. With the computed tomography data from subjects, a three-dimensional femur-pelvis-sacrum model was reconstructed, and the individualized musculoskeletal dynamics was analyzed using the ergonomics software, which derived the human joint forces and completed the mechanic model. Then, this study established a dual-arm robot transfer platform to conduct subject transfer experiments, showing that the constructed mechanics model possessed higher accuracy than previous methods. In summary, this study provides a three-dimensional human-robot mechanics model adapting to individual transfers, which has potential application in various scenarios such as nursing-care and rehabilitating robots.

关键词： Individualized Mechanics model Musculoskeletal multibody dynamics Nursing-care robots Transfer tasks