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REVISIT TO DIELECTRIC PROPERTIES OF FERRITE CERAMICS

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Journal of Advanced Dielectrics 2012年第3期2卷 6-18页

作者： L.B.KONG L.liU J.w.zHAI z.w.li z.H.YANG School of Materials Science and Engineering Nanyang Technological University 50 Nanyang Avenue Singapore 639798 Temasek Laboratories National University of Singapore 5A Engineering Drive 1Singapore 117411 Functional Materials Research Laboratory Tongji University Shanghai 200092 China

Dielectric properties offerrite ceramics have been less reported than their magnetic *** study indicated that ferrite ceramics with very low dielectric loss tangent can be developed byusing appropriate sintering aids,together with the optimization of other sintering parameters suchas sintering temperature and time *** various candidates of sintering aids,Bi_(2)O_(3)isthe most promising *** is important to find that the optimized concentration of sintering aid forfull densification is not sufficient to achieve lowest dielectric loss *** short review was aimed to summarize the understanding in microstructural evolution,grain growth,densificationand dielectric properties offerrite ceramics as a function of sintering aid concentration and sinteringparameters,which could be used as a guidance to develop ferrite ceramics with low dielectric losstangents for various applications.

关键词： Ferrite ceramics DC resistivity complex permittivity dielectric loss tangent densi-¯cation microstructure grain growth

使用扩散峰度MRI的深度学习方法预测直肠癌对新辅助放化疗的反应

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国际医学放射学杂志 2020年第5期 608-609页

作者： X.Y.zhang L.wang H.T.zhu z.w.li M.Ye X.T.li 刘朝曦 Department of Radiology Peking University Cancer Hospital & Institute

摘要评估局部进展期直肠癌对术前新辅助放化疗的反应仍具有一定的挑战性。近年来,深度学习(DL)已广泛应用于肿瘤的诊断和治疗,并获得了较好的效果。目的开发并验

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Targeting epigenetic mechanisms in amyloid-β-mediated Alzheimer’s pathophysiology:unveiling therapeutic potential

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Neural Regeneration Research 2025年第1期20卷 54-66页

作者： Jennie z.li Nagendran Ramalingam Shaomin li Ann Romney Center for Neurologic Diseases Brigham and Women’s Hospital and Harvard Medical SchoolBostonMAUSA

Alzheimer’s disease is a prominent chronic neurodegenerative condition characterized by a gradual decline in memory leading to *** evidence suggests that Alzheimer’s disease is associated with accumulating various amyloid-βoligomers in the brain,influenced by complex genetic and environmental *** memory and cognitive deficits observed during the prodromal and mild cognitive impairment phases of Alzheimer’s disease are believed to primarily result from synaptic *** life,environmental factors can lead to enduring changes in gene expression and the emergence of brain *** changes,known as epigenetic modifications,also play a crucial role in regulating the formation of synapses and their adaptability in response to neuronal *** this context,we highlight recent advances in understanding the roles played by key components of the epigenetic machinery,specifically DNA methylation,histone modification,and microRNAs,in the development of Alzheimer’s disease,synaptic function,and activity-dependent synaptic ***,we explore various strategies,including enriched environments,exposure to non-invasive brain stimulation,and the use of pharmacological agents,aimed at improving synaptic function and enhancing long-term potentiation,a process integral to epigenetic ***,we deliberate on the development of effective epigenetic agents and safe therapeutic approaches for managing Alzheimer’s *** suggest that addressing Alzheimer’s disease may require distinct tailored epigenetic drugs targeting different disease stages or pathways rather than relying on a single drug.

关键词： Alzheimer’s disease DNA methylation enriched environments histone modification microRNAs non-invasive brain stimulation synaptic plasticity

Superconductivity Observed in Tantalum Polyhydride at High Pressure

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Chinese Physics Letters 2023年第5期40卷 90-93页

作者：何鑫张昌玲李芷文张思佳闵保森张俊卢可赵建发史鲁川彭毅望贤成冯少敏宋静王鲁红 V.B.Prakapenka S.Chariton 刘浩哲靳常青 Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100190China Songshan Lake Materials Laboratory Dongguan 523808China Shanghai Advanced Research in Physical Sciences Shanghai 201203China Department of Geology University of Illinois at Urbana ChampaignUrbanaIllinois 61801USA Center for Advanced Radiations Sources University of ChicagoChicagoIllinois 60637USA Center for High Pressure Science&Technology Advanced Research Beijing 100094China

we report experimental discovery of tantalum polyhydride *** was synthesized under highpressure and high-temperature conditions using diamond anvil cell combined with in situ high-pressure laser heating *** superconductivity was investigated via resistance measurements at *** highest superconducting transition temperature T_(c)was found to be~30 K at 197 GPa in the sample that was synthesized at the same pressure with~2000 K *** transitions are shifted to low temperature upon applying magnetic fields that support the superconductivity *** upper critical field at zero temperatureμ_0H_(c2)(0)of the superconducting phase is estimated to be~20 T that corresponds to Ginzburg-Landau coherent length~40 *** results suggest that the superconductivity may arise from 143d phase of TaH_(3).It is,for the first time to our best knowledge,experimental realization of superconducting hydrides for the VB group of transition metals.

关键词： hydride resistance superconductivity

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小动脉征：T4a结肠癌分期的影像学特征

国际医学放射学杂志 2024年第2期 250-250页

作者： z.Guan z.w.li D.Yang T.Yu H.J.Jiang X.Y.zhang 束宏敏

摘要目的通过分析现有和新提出的pT1-3和pT4a期肿瘤的影像学特征分布，寻找一个显著特征并验证其诊断效能。方法回顾性收集2016年1月—2017年12月共3个中

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Epigenetic regulation of the inflammatory response in stroke

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Neural Regeneration Research 2025年第11期20卷 3045-3062页

作者： Jingyi liang Fei Yang zixiao li Qian li School of Basic Medical Sciences Capital Medical UniversityBeijingChina Department of Neurobiology School of Basic Medical SciencesCapital Medical UniversityBeijingChina Laboratory for Clinical Medicine Beijing Key Laboratory of Neural Regeneration and RepairCapital Medical UniversityBeijingChina Department of Neurology Beijing Tiantan HospitalCapital Medical UniversityBeijingChina China National Clinical Research Center for Neurological Diseases Beijing Tiantan HospitalCapital Medical UniversityBeijingChina National Center for Healthcare Quality Management in Neurological Diseases Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Chinese Institute for Brain Research BeijingChina Research Unit of Artificial Intelligence in Cerebrovascular Disease Chinese Academy of Medical SciencesBeijingChina Beijing Engineering Research Center of Digital Healthcare for Neurological Diseases BeijingChina Department of Biochemistry and Molecular Biology School of Basic Medical SciencesCapital Medical UniversityBeijingChina Beijing Key Laboratory of Cancer Invasion and Metastasis Research Capital Medical UniversityBeijingChina

Stroke is classified as ischemic or hemorrhagic,and there are few effective treatments for either *** mechanisms play a critical role in secondary brain injury following a stroke,which manifests as cytokine release,blood–brain barrier disruption,neuronal cell death,and ultimately behavioral *** the inflammatory response has been shown to mitigate this cascade of events in experimental stroke ***,in clinical trials of anti-inflammatory agents,longterm immunosuppression has not demonstrated significant clinical benefits for *** may be attributable to the dichotomous roles of inflammation in both tissue injury and repair,as well as the complex pathophysiologic inflammatory processes in *** acute harmful inflammatory responses or inducing a phenotypic shift from a pro-inflammatory to an anti-inflammatory state at specific time points after a stroke are alternative and promising therapeutic *** agents that can modulate inflammation requires a detailed understanding of the inflammatory processes of ***,epigenetic reprogramming plays a crucial role in modulating post-stroke inflammation and can potentially be exploited for stroke *** this review,we summarize current findings on the epigenetic regulation of the inflammatory response in stroke,focusing on key signaling pathways including nuclear factor-kappa B,Janus kinase/signal transducer and activator of transcription,and mitogen-activated protein kinase as well as inflammasome *** also discuss promising molecular targets for stroke *** evidence to date indicates that therapeutic targeting of the epigenetic regulation of inflammation can shift the balance from inflammation-induced tissue injury to repair following stroke,leading to improved post-stroke outcomes.

关键词： DNA methylation histone modification intracerebral hemorrhage ischemic stroke neuroinflammation neuroprotection non-coding RNA RNA methylation subarachnoid hemorrhage treatment

Transport mechanism in chemically reactive hybrid nanofluid flow containing gyrotactic micro-organisms over a curved oscillatory surface

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 177-192页

作者： M.NAVEED M.IMRAN T.ASGHAR z.ABBAS Department of Mathematics Division of Science and TechnologyUniversity of Education Department of Mathematics The Islamia University of Bahawalpur

This paper examines the transport analysis, including both heat transfer and mass transfer, in hybrid nanofluid flow containing gyrotactic microorganisms towards a curved oscillatory surface. The influence of magnetic fields is also inspected in terms of their physical characteristics. To depict the phenomena of transport, modified versions of both Fick's and Fourier's laws are used. Additionally, the characteristics of both heterogeneous and homogeneous chemical reactions are also incorporated. Utilizing a curvilinear coordinate system, the flow problem is formulated as partial differential equations(PDEs)for momentum, concentration, microorganism field, and energy. An analytical solution to the obtained flow equations is achieved utilizing the homotopy analysis method(HAM).The effects of significant flow parameters on the pressure and microorganism fields, velocity, oscillation velocity, concentration, and temperature distributions are shown via graphs. Furthermore, the variations in skin friction, mass transfer rate, heat transfer rate, and local motile number due to different involved parameters are presented in tables and are analyzed in detail. Graphical results indicate that the curves of velocity and temperature fields are enhanced as the values of the solid volume fraction variables *** is also verified that the concentration rate field decreases as the values of the homogeneous reaction strength parameter and the radius of curvature parameter increase, and it increases with the Schmidt number and the heterogeneous reaction strength *** outcomes show a favorable response of the motile number to advanced values of the Peclet number, the Schmidt number, the microorganism difference parameter, and the bio-convective Lewis number.

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Non-monotonic temperature evolution of nonlocal structure–dynamics correlation in Cuzr glass-forming liquids

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Chinese Physics B 2021年第7期30卷 370-375页

作者： w J Jiang M z li Department of Physics and Beijing Key Laboratory of Opto-electronic Functional Materials&Micro-nano Devices Renmin University of ChinaBeijing 100872China

The structure–dynamics correlations in a nonlocal manner were investigated in Cuzr metallic glass-forming liquids via classical molecular dynamics simulations.A spatial coarse-graining approach was employed to incorporate the nonlocal structural information of given structural order parameters in the structure–dynamics *** is found that the correlation between structure order parameters and dynamics increases with increasing coarse-graining length and has a characteristic length ***,the characteristic correlation length exhibits a non-monotonic temperature evolution as temperature approaches glass transition temperature,which is not sensitive to the considered structure order *** results unveil a striking change in the structure–dynamics correlation,which involves no fitting theoretical *** findings provide new insight into the structure–dynamics correlation in glass transition.

关键词： metallic glass-forming liquid structure–dynamics correlation molecular dynamics simulation

Exergy analysis of R1234ze（z） as high temperature heat pump working fluid with multi-stage compression

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Frontiers in Energy 2017年第4期11卷 493-502页

作者： Bin HU Di wU L.w. wANG R.z. wANG Institute of Refrigeration and Cryogenics Shanghai Jiao Tong University Shanghai 200240 China

In this paper, the simulation approach and exergy analysis of multi-stage compression high tempera- ture heat pump （HTHP） systems with R1234ze（z） working fluid are conducted. Both the single-stage and multi-stage compression cycles are analyzed to compare the system performance with 120℃ pressurized hot water supply based upon waste heat recovery. The exergy destruction ratios of each component for different stage compression systems are compared. The results show that the exergy loss ratios of the compressor are bigger than that of the evaporator and the condenser for the single-stage compres- sion system. The multi-stage compression system has better energy and exergy etticiencies with the increase of compression stage number. Compared with the single- stage compression system, the coefficient of performance （COP） improvements of the two-stage and three-stage compression system are 9.1% and 14.6%, respectively. when the waste heat source temperature is 60℃, the exergy efficiencies increase about 6.9% and 11.8% for the two-stage and three-stage compression system respec- tively.

关键词： multi-stage compression high temperatureheat pump heat recovery exergy destruction,R1234ze(z) working fluid