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Symmetry-Protected Scattering in Non-Hermitian Linear Systems

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Chinese Physics Letters 2021年第2期38卷 29-35页

作者： L.Jin z.song School of Physics Nankai UniversityTianjin 300071China

Symmetry plays fundamental role in physics and the nature of symmetry changes in non-Hermitian *** the symmetry-protected scattering in non-Hermitian linear systems is investigated by employing the discrete symmetries that classify the random *** even-parity symmetries impose strict constraints on the scattering coefficients:the time-reversal(C and K) symmetries protect the symmetric transmission or reflection;the pseudo-Hermiticity(Q symmetry) or the inversion(P) symmetry protects the symmetric transmission and *** the inversion-combined time-reversal symmetries,the symmetric features on the transmission and reflection *** odd-parity symmetries including the particle-hole symmetry,chiral symmetry,and sublattice symmetry cannot ensure the scattering to be *** guiding principles are valid for both Hermitian and non-Hermitian linear *** findings provide fundamental insights into symmetry and scattering ranging from condensed matter physics to quantum physics and optics.

关键词： symmetry symmetric parity

Topological Knots in Quantum Spin Systems

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Chinese Physics Letters 2021年第6期38卷 7-12页

作者： X.M.Yang L.Jin z.song School of Physics Nankai UniversityTianjin 300071China

Knot theory provides a powerful tool for understanding topological matters in biology,chemistry,and *** knot theory is introduced to describe topological phases in a quantum spin *** solvable models with long-range interactions are investigated,and Majorana modes of the quantum spin system are mapped into different knots and *** topological properties of ground states of the spin system are visualized and characterized using crossing and linking numbers,which capture the geometric topologies of knots and *** interactivity of energy bands is *** gapped phases,eigenstate curves are tangled and braided around each other,forming *** gapless phases,the tangled eigenstate curves may form *** findings provide an alternative understanding of phases in the quantum spin system,and provide insights into one-dimension topological phases of matter.

关键词： topological quantum system

Editorial for Special Issue on Commonsense Knowledge and Reasoning:Representation,Acquisition and Applications

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Machine Intelligence Research 2024年第2期21卷 215-216页

作者： Kang Liu Yangqiu song Jeff z.Pan Institute of Automation Chinese Academy of SciencesChina Hongkong University of Science and Technology China The University of Edinburgh UK

Commonsense knowledge is an important resource for humans to understand the meanings or semantics of the *** ability to learn and own commonsense knowledge is one of the major gaps between humans and *** recent research progresses about deep learning,like Transformer,pre-trained models,etc.,have made amazing breakthroughs in many fields,including computer version,natural language learning,etc.,letting the machines have rich commonsense knowledge and possess the reasoning ability is still difficult and under-resolved.

关键词： own let breakthrough

在OPERA试验中利用深度学习联合MRI T1无强化和强化病灶进行多发性硬化病灶分割

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国际医学放射学杂志 2022年第3期 355-355页

作者： A.P.Krishnan z.song D.Clayton L.Gaetano X.Jia A.deCrespigny 王璐娜

摘要基于深度学习的分割可快速、可重复性地评估T1序列中的强化病灶，对于多发性硬化症（MS）的疾病管理至关重要。MS中的T1无强化及强化病灶是指注入钆对比剂后

关键词：

Chronic administration of triclosan leads to liver fibrosis through hepcidin-ferroportin axis-mediated iron overload

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Journal of Environmental Sciences 2024年第3期137卷 144-154页

作者： Jing Liu Lecong zhang Fang Xu Ping zhang Yang song College of Eco-Environmental Engineering Guizhou Minzu UniversityGuiyang 550025China The Institute of Karst Wetland Ecology Guizhou Minzu UniversityGuiyang 550025China State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China

Triclosan(TCS)has been manufactured as an antibacterial compound for half a ***,it is widely used in various personal care products;however,its potential adverse effects raise a lot of ***,we create a long-term oral administration mouse model and identify the corresponding hepatotoxicity of *** discover that daily intragastric administration of 10 mg/kg TCS to mice for 12 weeks results in severe hepatic *** study displays that hepatic iron increased 18%,23%and 29%upon oral TCS treatment for4,8 and 12 weeks,*** by hepatic iron variation,splenic and duodenal iron are increased,which indicates systemic iron *** only excessive iron accumulated in the liver,abnormal hepatic malondialdehyde,prostaglandin synthase 2 and glutathione peroxidase 4 are pointed to *** study uncovers that hepcidin expression increases 7%,10%,4%in serum and 2.4-,4.8-,and 2.3-fold on transcriptional levels upon TCS exposure for 4,8 and 12 weeks,*** together,the mice in the TCS-treated group show disordered systemic iron homeostasis via the upregulated hepatic hepcidin-ferroportin ***,both hepatic iron overload(systemic level)and hepatocyte ferroptosis(cellular level)are accused of TCS-induced liver ***■,an iron scavenger,significantly ameliorates TCS-induced liver *** summary,this study confirms the impact of TCS on liver fibrosis;a critical signal pathway is also *** significance of the current study is to prompt us to reevaluate the“pros and cons”of TCS applications.

关键词： Triclosan Iron metabolism Hepcidin Hepatotoxicity Liver fibrosis

Design Strategies for Aqueous zinc Metal Batteries with High zinc Utilization: From Metal Anodes to Anode-Free Structures

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Nano-Micro Letters 2024年第4期16卷 305-349页

作者： Xianfu zhang Long zhang Xinyuan Jia Wen song Yongchang Liu School of Materials Science and Engineering University of Science and Technology Beijing30 College RoadBeijing 100083People’s Republic of China Beijing Advanced Innovation Center for Materials Genome Engineering Institute for Advanced Materials and TechnologyState Key Laboratory for Advanced Metals and MaterialsUniversity of Science and Technology BeijingBeijing 100083People’s Republic of China

Aqueous zinc metal batteries(AzMBs)are promising candidates for next-generation energy storage due to the excellent safety, environmental friendliness, natural abundance, high theoretical specific capacity, and low redox potential of zinc(zn) metal. However,several issues such as dendrite formation, hydrogen evolution, corrosion, and passivation of zn metal anodes cause irreversible loss of the active materials. To solve these issues, researchers often use large amounts of excess zn to ensure a continuous supply of active materials for zn anodes. This leads to the ultralow utilization of zn anodes and squanders the high energy density of AzMBs. Herein, the design strategies for AzMBs with high zn utilization are discussed in depth, from utilizing thinner zn foils to constructing anode-free structures with theoretical zn utilization of 100%, which provides comprehensive guidelines for further research. Representative methods for calculating the depth of discharge of zn anodes with different structures are first summarized. The reasonable modification strategies of zn foil anodes, current collectors with pre-deposited zn, and anode-free aqueous zn metal batteries(AF-AzMBs) to improve zn utilization are then detailed. In particular, the working mechanism of AF-AzMBs is systematically introduced. Finally, the challenges and perspectives for constructing high-utilization zn anodes are presented.

关键词： Aqueous zinc metal batteries zinc anodes High zinc utilization Depth of discharge Anode-free structures

Antibacterial and cytotoxic metabolites produced by Streptomyces tanashiensis BYF-112 isolated from Odontotermes formosanus

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Chinese Journal of Natural Medicines 2024年第9期22卷 822-830页

作者： WU J. song T. zHANG L. HUANG z. HUANG F. YIN C. zHANG S. LIU X. zHANG Y. School of Life Science Anhui Agricultural University Hefei 230036 China School of Pharmacy Anhui Medical University Hefei 230036 China

Chemical investigations of the termite-associated Streptomyces tanashiensis BYF-112 resulted in the discovery of four novel alkaloid derivatives: vegfrecines A and B (1 and 2), exfoliazone A (3), and venezueline H (7), in addition to nine known metabolites (4−6, 8−13). The structures of these compounds were elucidated through comprehensive spectroscopic analysis and comparison with existing literature data. Antibacterial assays revealed that viridomycin A (11) exhibited potent antibacterial activity against Staphylococcus aureus, with a zone of inhibition (zOI) of 12.67 mm, in comparison to a zOI of 17.67 mm for the positive control gentamicin sulfate. Viridomycin A (11) showed moderate activity against Micrococcus tetragenus and Pseudomonas syringae pv. actinidae, with zOI values of 15.50 and 14.33 mm, respectively, which were inferior to those of gentamicin sulfate (34.67 and 24.00 mm). Viridomycin F (12) also exhibited moderate antibacterial effects against S. aureus, M. tetragenus, and P. syringae pv. actinidae, with zOI values of 8.33, 16.50, and 10.83 mm, respectively. Cytotoxicity assays demonstrated that viridobruunine A (5), exfoliazone (6), viridomycin A (11), and X-14881E (13) exhibited significant cytotoxicity against human malignant melanoma (A375), ovarian cancer (SKOV-3), and gastric cancer (MGC-803) cell lines, with IC50 values ranging from 4.61 to 19.28 μmol·L−1. Furthermore, bioinformatic analysis of the complete genome of S. tanashiensis suggested a putative biosynthetic gene cluster (BGC) responsible for the production of compounds 1−12. These findings indicate that the secondary metabolites of insect-associated S. tanashiensis BYF-112 hold promise as potential sources of novel antibacterial and anticancer agents. © 2024 China Pharmaceutical University

关键词： Alkaloid Antibacterial activity Biosynthetic pathway Cytotoxic activity Odontotermes formosanus Streptomyces tanashiensis

The role of inflammasomes in human diseases and their potential as therapeutic targets

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Signal Transduction and Targeted Therapy 2024年第2期9卷 479-508页

作者： Jing Yao Keenan Sterling zhe Wang Yun zhang Weihong song The National Clinical Research Center for Geriatric Disease Xuanwu HospitalCapital Medical UniversityBeijing 100053China Townsend Family Laboratories Department of PsychiatryBrain Research CenterThe University of British Columbia2255 Wesbrook MallVancouverBC V6T 1Z3Canada Key Laboratory of Neurodegenerative Diseases Ministry of EducationBeijingP.R.China zhejiang Clinical Research Center for Mental Disorders Key Laboratory of Alzheimer’s Disease of Zhejiang ProvinceSchool of Mental Health and The Affiliated Kangning HospitalInstitute of AgingWenzhou Medical UniversityWenzhouZhejiang 325000China Oujiang Laboratory(zhejiang Lab for Regenerative Medicine Vision and Brain Health)WenzhouZhejiang 325000China

Inflammasomes are large protein complexes that play a major role in sensing inflammatory signals and triggering the innate immune *** inflammasome complex has three major components:an upstream sensor molecule that is connected to a downstream effector protein such as caspase-1 through the adapter protein *** formation typically occurs in response to infectious agents or cellular *** active inflammasome then triggers caspase-1 activation,followed by the secretion of pro-inflammatory cytokines and pyroptotic cell *** inflammasome activation and activity contribute to the development of diabetes,cancer,and several cardiovascular and neurodegenerative *** a result,recent research has increasingly focused on investigating the mechanisms that regulate inflammasome assembly and activation,as well as the potential of targeting inflammasomes to treat various *** clinical trials are currently underway to evaluate the therapeutic potential of several distinct inflammasome-targeting ***,understanding how different inflammasomes contribute to disease pathology may have significant implications for developing novel therapeutic *** this article,we provide a summary of the biological and pathological roles of inflammasomes in health and *** also highlight key evidence that suggests targeting inflammasomes could be a novel strategy for developing new disease-modifying therapies that may be effective in several conditions.

关键词： inflam therapeutic potential

Recent progress in the research on magnesium and magnesium alloy foils:A short review

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International Journal of Minerals,Metallurgy and Materials 2024年第5期31卷 842-854页

作者： Qiuyan Shen Yongxing Ba Peng zhang Jiangfeng song Bin Jiang Fusheng Pan National Engineering Research Center for Magnesium Alloys Chongqing UniversityChongqing 400044China College of Materials Science and Engineering Chongqing UniversityChongqing 400044China National Key Laboratory of Advanced Casting Technologies Chongqing UniversityChongqing 400044China

Magnesium and magnesium alloy foils have great potential for application in battery anodes,electromagnetic shielding,optics and acoustics,and biology because of their excellent specific damping,internal dissipation coefficients,magnetic and electrical conductivities,as well as high theoretical specific ***,magnesium alloys exhibit poor deformation ability due to their hexagonal close-packed crystal *** magnesium and magnesium alloy foils with thicknesses of less than 0.1 mm is difficult because of surface oxidation and grain growth at high temperatures or severe anisotropy after cold rolling that leads to *** methods have been applied to prepare magnesium alloy *** include warm rolling,cold rolling,accumulative roll bonding,electric plastic rolling,and on-line heating *** of magnesium and magnesium alloy foils during preparation,such as edge cracks and breakage,are important factors for ***,the current status of the research on magnesium and magnesium alloy foils is summarized from the aspects of foil preparation,defect control,performance characterization,and application *** advantages and disadvantages of different preparation methods and defect(edge cracks and breakage)mechanisms in the preparation of foils are identified.

关键词： magnesium alloy foil rolling defect performance application