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Measurement of the absolute branching fraction of D^+→K^0e^+v_e via K^0→π~0π~0

Chinese Physics C 2016年第11期40卷 5-13页

作者：麦迪娜 M.N.Achasov 艾小聪 O.Albayrak M.Albrecht D.J.Ambrose A.Amoroso 安芬芬安琪白景芝 R.Baldini Ferroli 班勇 D.W.Bennett J.V.Bennett M.Bertani D.Bettoni 边渐鸣 F.Bianchi E.Boger I.Boyko R.A.Briere 蔡浩蔡啸 O.Cakir A.Calcaterra 曹国富 S.A.Cetin 常劲帆 G.Chelkov 陈刚陈和生陈海云陈江川陈玛丽陈实陈申见谌炫陈旭荣陈元柏程和平褚新坤 G.Cibinetto 代洪亮代建平 A.Dbeyssi D.Dedovieh 邓子艳 A.Denig I.Denysenko M.Destefanis F.De Mori 丁勇董超董静董燎原董明义豆正磊杜书先段鹏飞范荆州方建房双世方馨方易 R.Farinelli l.Fava O.Fedorov F.Feldbauer G.Felici 封常青 E.Fioravanti M.Fritsch 傅成栋高清高鑫磊高旭阳高原宁高榛 I.Garzia K.Goetzen 龚丽龚文煊 W.Gradl M.Greco 顾旻皓顾运厅管颖慧郭爱强郭立波郭如盼郭玥郭玉萍 z.Haddadi A.Hafner 韩爽郝喜庆 F.A.Harris 何康林 T.Held 衡月昆侯治龙胡琛胡海明胡继峰胡涛胡誉黄光顺黄金书黄性涛黄晓忠黄勇黄智玲 T.Hussain 纪全姬清平季晓斌季筱璐姜鲁文江晓山蒋兴雨焦健斌焦铮金大鹏金山 T.Johansson A.Julin N.Kalantar-Nayestanaki 康晓琳康晓珅 M.Kavatsyuk 柯百谦 P.Kiese R.Kliemt B.Kloss O.B.Kolcu B.Kopf M.Kornicer A.Kupsc W.Kühn J.S.lange M.lara P.larin C.leng 李翠李澄李德民李飞李峰云李刚李海波李惠静李家才李瑾李康李科李蕾李培荣李启云李腾李卫东李卫国李晓玲李小男李学潜李郁博李志兵梁昊梁勇飞梁羽铁廖广睿林德旭刘冰刘北江刘春秀刘栋刘福虎刘芳刘峰刘宏邦刘汇慧刘欢欢刘怀民刘杰刘建北刘觉平刘晶译刘凯刘魁勇刘兰雕刘佩莲刘倩刘树彬刘翔刘玉斌刘振安刘智青 H.loehner 娄辛丑吕海江吕军光卢宇卢云鹏罗成林罗民兴 T.luo 罗小兰吕晓睿马凤才马海龙马连良马明明马秋梅马天马旭宁马骁妍马玉明 F.E.Maas M.Maggiora 冒亚军毛泽普 S.Marcello J.G.Messchendorp 闵建闵天觉 R.E.Mitchell 莫晓虎莫玉俊 C.Morales Morales N.Yu.Muchnoi H.Muramatsu Y.Nefedov F.Nerling I.B.Nikolaev 宁哲 S.Nisar 牛顺利牛讯伊馬鵬欧阳群 S.Pacetti 潘越 P.Patteri M.Pelizaeus 彭海平 K.Peters J.Pettersson 平加伦平荣刚 R.Poling V.Prasad 漆红荣祁鸣钱森乔从丰秦丽清覃拈秦小帅秦中华邱进发 K.H.Rashid C.F.Redmer M.Ripka 荣刚 Ch.Rosner 阮向东 A.Sarantsev M.Savrie K.Schoenning S.Schumann 单葳邵明沈成平沈培迅沈肖雁盛华义施萌宋维民宋欣颖 S.Sosio S.Spataro 孙功星孙俊峰孙胜森孙新华孙勇杰孙永昭孙志嘉孙振田唐昌建唐晓 I.Tapan E.H.Thorndike M.Tiemens M.ullrich I.uman G.S.Yarner 王斌王滨龙王东王大勇王科王亮亮王灵淑王萌王平王佩良王炜王维平王雄飞王越王雅迪王贻芳王亚乾王铮王志刚王志宏王至勇王宗源 T.Weber 魏代会 P.Weidenkaff 文硕频 u.Wiedner M.Wolke 伍灵慧吴连近吴智夏磊夏力钢夏宇肖栋肖浩肖振军谢宇广修青磊许国发徐静静徐雷徐庆君徐庆年徐新平严亮鄢文标闫文成颜永红杨海军杨洪勋杨柳杨永栩叶梅叶铭汉殷俊昊俞伯祥喻纯旭俞洁晟苑长征袁文龙袁野 A.Yuncu A.A.zafar A.zallo 曾云曾哲张丙新张炳云张驰张长春张达华张宏浩章红宇张晋张佳佳 Institute of High Energy Physics G.I.Budker Institute of Nuclear Physics SB RAS BINP the Novosibirsk State university Carnegie Mellon university Bochum Ruhr-university university of Rochester university of Turin INFN university of Science and Technology of China State Key laboratory of Particle Detection and Electronics INFN laboratori Nazionali di Frascati Peking university Indiana university INFN Sezione di Ferrara university of Minnesota Joint Institute for Nuclear Research the Moscow Institute of Physics and Technology Carnegie Mellon university PittsburghPennsylvania 15213USA Central China Normal university Wuhan university Ankara university Istanbul Bilgi university the Functional Electronics laboratory Tomsk State University Beihang university university of Chinese Academy of Sciences Nanjing university lanzhou university Huangshan College Shanghai Jiao Tong university Helmholtz Institute Mainz Johannes Gutenberg university of Mainz liaoning university Nankai university zhengzhou university Tsinghua university university of Ferrara university of Eastern Piedmont GSI Helmholtzcentre for Heavy Ion Research GmbH Guangxi university Nanjing Normal university KVI-CART University of Groningen Henan Normal university university of Hawaii uludag university Shandong university university of the Punjab uppsala university Istanbul Axel university Justus-liebig-universitaet Giessen Ⅱ.Physikalisches Institut Seoul National university Hangzhou Normal university Beijing Institute of Petrochemical Technology Sun Yat-Sen university Sichuan university Guangxi Normal university Shanxi university Henan university of Science and Technology university of Texas at Dallas zhejiang university G.I.Budker Institute of Nuclear Physics SB RAS(BINP) COMSATS Institute of Information Technology INFN and university of Perugia Goethe university Frankfurt the NRC "Kurchatov Institute PNPI Near East university NicosiaNorth Cyprus Soochow university Hunan university university of South China China Center of Advanced Science and Technology B

By analyzing 2.93 fb-1 data collected at the center-of-mass energy v/S = 3.773 GeV with the BESIII detector, we measure the absolute branching fraction of the semileptonic decay D＋- k0e＋ ve via k0-π0π0 - （8.59 ± 0.14 ± 0.21）% using k0- k0-π0π0, where the first uncertainty is statistical and the second systematic. Our result is consistent with previous measurements within uncertainties..

关键词： charmed mesons semileptonic decays absolute branching fraction BESIII/BEPCII

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Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma

引用

Frontiers of Medicine 2021年第2期15卷 275-291页

作者： Na qin Yuancheng li Cheng Wang Meng zhu Juncheng Dai Tongtong Hong Demetrius Albanes Stephen lam Adonina Tardon Chu Chen Gary Goodman Stig EBojesen Maria Teresa landi Mattias Johansson Angela Risch H-Erich Wichmann Heike Bickeboller Gadi Rennert Susanne Arnold Paul Brennan John KField Sanjay Shete loic le Marchand Olle Melander Hans Brunnstrom Geoffrey liu Rayjean JHung Angeline Andrew lambertus AKiemeney Shan zienolddiny Kjell Grankvist Mikael Johansson Neil Caporaso Penella Woll Philip lazarus Matthew BSchabath Melinda CAldrich Victoria lStevens Guangfu Jin David CChristiani zhibin Hu Christopher IAmos Hongxia Ma Hongbing Shen Department of Epidemiology Center for Global HealthSchool of Public HealthNanjing Medical UniversityNanjing 211166China State Key laboratory of Reproductive Medicine Center for Global HealthNanjing Medical UniversityNanjing 211166China Department of Bioinformatics School of Biomedical Engineering and InformaticsNanjing Medical UniversityNanjing 211166China Jiangsu Key lab of Cancer Biomarkers Prevention and TreatmentCollaborative Innovation Center for Cancer MedicineNanjing Medical UniversityNanjing 211166China China International Cooperation Center for Environment and Human Health School of Public HealthNanjing Medical UniversityNanjing 211166China Division of Cancer Epidemiology and Genetics National Cancer InstituteBethesdaMD 20892-9304USA Department of Integrative Oncology British Columbia Cancer AgencyVancouverBC V5Z 1L3Canada Faculty of Medicine University of Oviedo and CIBERESPOviedo 33006Spain Program in Epidemiology Public Health Sciences DivisionFred Hutchinson Cancer Research CenterSeattleWA 98109-1024USA Public Health Sciences Division Swedish Cancer InstituteSeattleWA 98026USA Department of Clinical Biochemistry Copenhagen University HospitalCopenhagen DK-1017Denmark National Cancer Institute BethesdaMD 20892-9304USA Genetic Epidemiology Group International Agency for Research on CancerLyon 69372France Cancer Center Cluster Salzburg at PluS Department of Molecular BiologyUniversity of SalzburgHeidelberg 5020Austria Institute of Medical Informatics Biometry and EpidemiologyChair of EpidemiologyLudwig Maximilians UniversityMunichBavaria 80539Germany Department of Genetic Epidemiology University Medical Center GoettingenGoettingen 37075Germany Technion Faculty of Medicine Carmel Medical CenterHaifa 3448516Israel Markey Cancer Center University of KentuckyLexingtonKY 40506-0054USA Department of Molecular and Clinical Cancer Medicine Roy Castle Lung Cancer Research ProgrammeThe University of Liverpool Institute of Translational MedicineLiverpool L697Z

Although genome-wide association studies have identified more than eighty genetic variants associated with non-small cell lung cancer(NSClC)risk,biological mechanisms of these variants remain largely *** integrating a large-scale genotype data of 15581 lung adenocarcinoma(AD)cases,8350 squamous cell carcinoma(SqCC)cases,and 27355 controls,as well as multiple transcriptome and epigenomic databases,we conducted histology-specific meta-analyses and functional annotations of both reported and novel susceptibility *** identified 3064 credible risk variants for NSClC,which were overrepresented in enhancer-like and promoter-like histone modification peaks as well as DNase I hypersensitive *** factor enrichment analysis revealed that uSF1 was AD-specific while CREB1 was *** annotation and genebased analysis implicated 894 target genes,including 274 specifics for AD and 123 for SqCC,which were overrepresented in somatic driver genes(ER=1.95,P=0.005).Pathway enrichment analysis and Gene-Set Enrichment Analysis revealed that AD genes were primarily involved in immune-related pathways,while SqCC genes were homologous recombination deficiency *** results illustrate the molecular basis of both wellstudied and new susceptibility loci of NSClC,providing not only novel insights into the genetic heterogeneity between AD and SqCC but also a set of plausible gene targets for post-GWAS functional experiments.

关键词： lung cancer genome-wide association study function annotation immune homologous recombination repair deficiency genetic heterogeneity

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