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Targeting epigenetic mechanisms in amyloid-β-mediated Alzheimer’s pathophysiology:unveiling therapeutic potential

Neural Regeneration Research 2025年第1期20卷 54-66页

作者： Jennie z.li Nagendran Ramalingam Shaomin li Ann Romney Center for Neurologic Diseases Brigham and Women’s Hospital and Harvard Medical SchoolBostonMAUSA

Alzheimer’s disease is a prominent chronic neurodegenerative condition characterized by a gradual decline in memory leading to *** evidence suggests that Alzheimer’s disease is associated with accumulating various amyloid-βoligomers in the brain,influenced by complex genetic and environmental *** memory and cognitive deficits observed during the prodromal and mild cognitive impairment phases of Alzheimer’s disease are believed to primarily result from synaptic *** life,environmental factors can lead to enduring changes in gene expression and the emergence of brain *** changes,known as epigenetic modifications,also play a crucial role in regulating the formation of synapses and their adaptability in response to neuronal *** this context,we highlight recent advances in understanding the roles played by key components of the epigenetic machinery,specifically DNA methylation,histone modification,and microRNAs,in the development of Alzheimer’s disease,synaptic function,and activity-dependent synaptic ***,we explore various strategies,including enriched environments,exposure to non-invasive brain stimulation,and the use of pharmacological agents,aimed at improving synaptic function and enhancing long-term potentiation,a process integral to epigenetic ***,we deliberate on the development of effective epigenetic agents and safe therapeutic approaches for managing Alzheimer’s *** suggest that addressing Alzheimer’s disease may require distinct tailored epigenetic drugs targeting different disease stages or pathways rather than relying on a single drug.

关键词： Alzheimer’s disease DNA methylation enriched environments histone modification microRNAs non-invasive brain stimulation synaptic plasticity

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Search for electron-antineutrinos associated with gravitational-wave events GW150914,GW151012,GW151226,GW170104,GW170608,GW170814,and GW170817 at Daya bay

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Chinese Physics C 2021年第5期45卷 190-201页

作者： F.P.An A.b.balantekin H.R.band M.bishai S.blyth G.F.Cao J.Cao J.F.Chang Y.Chang H.S.Chen S.M.Chen Y.Chen Y.X.Chen J.Cheng z.K.Cheng J.J.Cherwinka M.C.Chu J.P.Cummings O.Dalager F.S.Deng Y.Y.Ding M.V.Diwan T.Dohnal J.Dove M.Dvorak D.A.Dwyer J.P.Gallo M.Gonchar G.H.Gong H.Gong W.Q.Gu J.Y.Guo L.Guo X.H.Guo Y.H.Guo z.Guo R.W.Hackenburg S.Hans M.He K.M.Heeger Y.K.Heng A.Higuera Y.K.Hor Y.b.Hsiung b.z.Hu J.R.Hu T.Hu z.J.Hu H.X.Huang X.T.Huang Y.b.Huang P.Huber D.E.Jaffe K.L.Jen X.L.Ji X.P.Ji R.A.Johnson D.Jones L.Kang S.H.Kettell S.Kohn M.Kramer T.J.Langford J.Lee J.H.C.Lee R.T.Lei R.Leitner J.K.C.Leung F.li J.J.li Q.J.li S.li S.C.li W.D.li X.N.li X.Q.li Y.F.li z.b.li H.liang C.J.lin G.L.lin S.lin J.J.ling J.M.link L.littenberg b.R.littlejohn J.C.liu J.L.liu C.Lu H.Q.Lu J.S.Lu K.b.Luk X.b.Ma X.Y.Ma Y.Q.Ma C.Marshall D.A.Martinez Caicedo K.T.MeDonald R.D.McKeown Y.Meng J.Napolitano D.Naumov E.Naumova J.P.Ochoa-Ricoux A.OIshevskiy H.-R.Pan J.Park S.Patton J.C.Peng C.S.J.Pun F.z.Qi M.Qi X.Qian N.Raper J.Ren C.Morales Reveco R.Rosero b.Roskovec X.C.Ruan H.Steiner J.L.Sun T.Tmej K.Treskov W.-H.Tse C.E.Tull b.Viren V.Vorobel C.H.Wang J.Wang M.Wang N.Y.Wang R.G.Wang W.Wang W.Wang X.Wang Y.Wang Y.F.Wang z.Wang z.Wang z.M.Wang H.Y.Wei L.H.Wei L.J.Wen K.Whisnant C.G.White H.L.H.Wong E.Worcester D.R.Wu F.L.Wu Q.Wu W.J.Wu D.M.Xia z.Q.Xie z.z.Xing J.L.Xu T.Xu T.Xue C.G.Yang L.Yang Y.z.Yang H.F.Yao M.Ye M.Yeh b.L.Young H.z.Yu z.Y.Yu b.b.Yue S.zeng Y.zeng L.zhan C.zhang F.Y.zhang H.H.zhang J.W.zhang Q.M.zhang X.T.zhang Y.M.zhang Y.X.zhang Y.Y.zhang z.J.zhang z.P.zhang z.Y.zhang J.zhao L.zhou H.L.zhuang J.H.zou Instiute of Modern Physics East China University of Science and TechnologyShanghai 200237 University of Wisconsin MadisonWisconsin 53706 Wright Laboratory and Department of Physics Yale UniversityNew HavenConnecticut 06520 brookhaven National Laboratory UptonNew York 11973 Department of Physics National Taiwan UniversityTaipei Institute of High Energy Physics Beijing 100049 National United University Miao-Li Department of Engineering Physics Tsinghua UniversityBejing 100084 Shenzhen University Shenzhen 518060 Sun Yat-Sen(zhongshan)University Guangzhou North China Electric Power University Bejjing 102206 Chinese University of Hong Kong Hong Kong 999077 Siena College LoudonvilleNew York 12211 Department of Physics and Astronomy University of CaliforniaIrvineCaliformia 92697 University of Science and Technology of China Hefei 230026 Charles University Faculty of Mathematics and PhysicsPrague Department of Physics University of llinois at Urbana-ChampaignUrbanaIlinois 61801 Lawrence berkeley National Laboratory BerkeleyCalifornia 94720 Department of Physics Illinois Institute of TechnologyChicagoIllinois 60616 Joint Institute for Nuclear Research DubnaMoscow Region beijing Normal University Beijing 100875 Department of Nuclear Science and Technology School of Energy and Power EngineeringXi'an Jiaotong UniversityXi'an 710049 Department of Physics University of HoustonHoustonTexas 77204 China Institute of Atomic Energy Beijing 102413 Shandong University Jinan 250100 Guangxi University Nanning 530004 Center for Neutrino Physics Virginia TechBlacksburgVirginia 24061 Institute of Physics National Chiao-Tung UniversityHsinchu Department of Physics University of CincinnatiCincinnatiOhio 45221 Department of Physies Collge of Science and TechnologyTemple UniversityPhiladelphiaPennsylvania 19122 Dongguan University of Technology Dongguan 523808 Department of Physics University of CaliforniaBerkeleyCalifornia 94720 Department of Physics The University of Hong KongPokfulamHong Kong 999077 School

The establishment of a possible connection between neutrino emission and gravitational-wave(GW)bursts is important to our understanding of the physical processes that occur when black holes or neutron stars *** the Daya bay experiment,using the data collected from December 2011 to August 2017,a search was per-formed for electron-antineutrino signals that coincided with detected GW events,including GW150914,GW151012,GW151226,GW170104,GW170608,GW 170814,and GW *** used three time windows of±10,±500,and±1000 s relative to the occurrence of the GW events and a neutrino energy range of 1.8 to 100 MeV to search for correlated neutrino *** detected electron-antineutrino candidates were consistent with the expected background rates for all the three time *** monochromatic spectra,we found upper limits(90%confidence level)of the electron-antineutrino fluence of(1.13-2.44)×10^(11)cm^(-2)at 5 MeV to 8.0×10^(7)cm^(-2)at 100 MeV for the three time w *** the assumption of a Fermi-Dirac spectrum,the upper limits were found to be(5.4-7.0)×10^(9)cm^(2)for the three time windows.

关键词： grav itational waves electron-antineutrinos fluence upper limit

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Future Physics Programme of bESⅢ

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Chinese Physics C 2020年第4期44卷 I0001-I0004,1-102页

作者： M.Ablikim M.N.Achasov P.Adlarson S.Ahmed M.Albrecht M.Alekseev A.Amoroso F.F.An Q.An Y.bai O.bakina R.baldini Ferroli Y.ban K.begzsuren J.V.bennett N.berger M.bertani D.bettoni F.bianchi J biernat J.bloms I.boyko R.A.briere L.Calibbi H.Cai X.Cai A.Calcaterra G.F.Cao N.Cao S.A.Cetin J.Chai J.F.Chang W.L.Chang J.Charles G.Chelkov Chen G.Chen H.S.Chen J.C.Chen M.L.Chen S.J.Chen Y.b.Chen H.Y.Cheng W.Cheng G.Cibinetto F.Cossio X.F.Cui H.L.Dai J.P.Dai X.C.Dai A.Dbeyssi D.Dedovich z.Y.Deng A.Denig Denysenko M.Destefanis S.Descotes-Genon F.De Mori Y.Ding C.Dong J.Dong L.Y.Dong M.Y.Dong z.L.Dou S.X.Du S.I.Eidelman J.z.Fan J.Fang S.S.Fang Y.Fang R.Farinelli L.Fava F.Feldbauer G.Felici C.Q.Feng M.Fritsch C.D.Fu Y.Fu Q.Gao X.L.Gao Y.Gao Y.Gao Y.G.Gao z.Gao b.Garillon I.Garzia E.M.Gersabeck A.Gilman K.Goetzen L.Gong W.X.Gong W.Gradl M.Greco L.M.Gu M.H.Gu Y.T.Gu A.Q.Guo F.K.Guo L.b.Guo R.P.Guo Y.P.Guo A.Guskov S.Han X.Q.Hao F.A.Harris K.L.He F.H.Heinsius T.Held Y.K.Heng Y.R.Hou z.L.Hou H.M.Hu J.F.Hu T.Hu Y.Hu G.S.Huang J.S.Huang X.T.Huang X.z.Huang z.L.Huang N.Huesken T.Hussain W.Ikegami Andersson W.Imoehl M.Irshad Q.Ji Q.P.Ji X.b.Ji X.L.Ji H.L.Jiang X.S.Jiang X.Y.Jiang J.b.Jiao z.Jiao D.P.Jin S.Jin Y.Jin T.Johansson N.Kalantar-Nayestanaki X.S.Kang R.Kappert M.Kavatsyuk b.C.Ke I.K.Keshk T.Khan A.Khoukaz P.Kiese R.Kiuchi R.Kliemt L.Koch O.b.Kolcu b.Kopf M.Kuemmel M.Kuessner A.Kupsc M.Kurth M.G.Kurth W.Kuhn J.S.Lange P.Larin L.Lavezzi H.Leithoff T.Lenz C.li Cheng li D.M.li F.li F.Y.li G.li H.b.li H.J.li J.C.li J.W.li Ke li L.K.li Lei li P.L.li P.R.li Q.Y.li W.D.li W.G.li X.H.li X.L.li X.N.li X.Q.li z.b.li H.liang H.liang Y.F.liang Y.T.liang G.R.liao L.z.liao J.libby C.X.lin D.X.lin Y.J.lin b.liu b.J.liu C.X.liu D.liu D.Y.liu F.H.liu Fang liu Feng liu H.b.liu H.M.liu Huanhuan liu Huihui liu J.b.liu J.Y.liu K.Y.liu Ke liu Q.liu S.b.liu T.liu X.liu X.Y.liu Y.b.liu z.A.liu zhiqing liu Y.F.Long X.C.Lou H.J.Lu J.D.Lu J.G.Lu Y.Lu Y.P.Lu C.L.Luo M.X.Luo P.W.Luo T.Luo X.L.Luo S.Lusso X.R.Lyu F.C.Ma H.L.Ma L.L.Ma M.M.Ma Q.M.Ma X.N.Ma X.X. Institute of High Energy Physics Beijing 100049China beihang University Beijing 100191China beijing Institute of Petrochemical Technology Beijing 102617China bochum Ruhr-University D-44780 BochumGermany Carnegie Mellon University PittsburghPennsylvania 15213USA Central China Normal University Wuhan 430079China China Center of Advanced Science and Technology Beijing 100190China COMSATS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan Fudan University Shanghai 200443China G.I.budker Institute of Nuclear Physics Sb RAS(bINP) Novosibirsk 630090Russia GSI Helmholtzcentre for Heavy Ion Research GmbH D-64291 DarmstadtGermany Guangxi Normal University Guilin 541004China Guangxi University Nanning 530004China Hangzhou Normal University Hangzhou 310036China Helmholtz Institute Mainz Johann-Joachim-Becher-Weg 45D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University of Science and Technology Luoyang 471003China Huangshan College Huangshan 245000China Hunan Normal University Changsha 410081China Hunan University Changsha 410082China Indian Institute of Technology Madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INFN Laboratori Nazionali di Frascati I-00044FrascatiItaly INFN Sezione di Ferrara I-44122FerraraItaly Institute of Physics and Technology Peace Ave.54BUlaanbaatar 13330Mongolia Johannes Gutenberg University of Mainz Johann-Joachim-Becher-Weg 45D-55099 MainzGermany Joint Institute for Nuclear Research 141980 DubnaMoscow regionRussia Justus-liebig-Universitaet Giessen II.Physikalisches InstitutHeinrich-Buff-Ring 16D-35392 GiessenGermany KVI-CART University of GroningenNL-9747 AA GroningenThe Netherlands Lanzhou University Lanzhou 730000China liaoning University Shenyang 110036China Nanjing Normal University Nanjing 210023China Nanjing University Nanjing 210093China Nankai University Tianjin 300071China Peking University Beijing 100871China Shandong University Jinan 250100China Shanghai

There has recently been a dramatic renewal of interest in hadron spectroscopy and charm physics. This renaissance has been driven in part by the discovery of a plethora of charmonium-like XYz states at bESⅢ and b factories, and the observation of an intriguing proton-antiproton threshold enhancement and the possibly related X(1835) meson state at bESⅢ, as well as the threshold measurements of charm mesons and charm baryons. We present a detailed survey of the important topics in tau-charm physics and hadron physics that can be further explored at bESⅢ during the remaining operation period of bEPCⅡ. This survey will help in the optimization of the data-taking plan over the coming years, and provides physics motivation for the possible upgrade of bEPCⅡ to higher luminosity.

关键词： meson hadron optimization

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Antineutrino energy spectrum unfolding based on the Daya bay measurement and its applications

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Chinese Physics C 2021年第7期45卷 1-19页

作者： F.P.An A.b.balantekin M.bishai S.blyth G.F.Cao J.Cao J.F.Chang Y.Chang H.S.Chen S.M.Chen Y.Chen Y.X.Chen J.Cheng z.K.Cheng J.J.Cherwinka M.C.Chu J.P.Cummings O.Dalager F.S.Deng Y.Y.Ding M.V.Diwan T.Dohnal D.Dolzhikov J.Dove M.Dvorak D.A.Dwyer J.P.Gallo M.Gonchar G.H.Gong H.Gong M.Grassi W.Q.Gu J.Y.Guo L.Guo X.H.Guo Y.H.Guo z.Guo R.W.Hackenburg S.Hans a M.He K.M.Heeger Y.K.Heng Y.K.Hor Y.b.Hsiung b.z.Hu J.R.Hu T.Hu z.J.Hu H.X.Huang J.H.Huang X.T.Huang Y.b.Huang P.Huber D.E.Jaffe K.L.Jen X.L.Ji X.P.Ji R.A.Johnson D.Jones L.Kang S.H.Kettel S.Kohn M.Kramer T.J.Langford J.Lee J.H.C.Lee R.T.Lei R.Leitner J.K.C.Leung F.li H.L.li J.J.li Q.J.li R.H.li S.li S.C.li W.D.li X.N.li X.Q.li Y.F.li z.b.li H.liang C.J.lin G.L.lin S.lin J.J.ling J.M.link26 L.littenberg b.R.littlejohn J.C.liu J.L.liu J.X.liu C.Lu H.Q.Lu K.b.Luk b.z.Ma X.b.Ma X.Y.Ma Y.Q.Ma R.C.Mandujano C.Marshall K.T.McDonald R.D.McKeown Y.Meng J.Napolitano D.Naumov E.Naumova T.M.T.Nguyen J.P.Ochoa-Ricoux A.Olshevskiy H.-R.Pan J.Park S.Patton J.C.Peng C.S.J.Pun F.z.Qi M.Qi X.Qian N.Raper J.Ren C.Morales Reveco R.Rosero b.Roskovec X.C.Ruan H.Steiner J.L.Sun T.Tmej1 K.Treskov W.-H.Tse C.E.Tull b.Viren V.Vorobel C.H.Wang J.Wang M.Wang N.Y.Wang R.G.Wang W.Wang W.Wang X.Wang Y.Wang Y.F.Wang z.Wang z.Wang z.M.Wang H.Y.Wei L.H.Wei L.J.Wen K.Whisnant C.G.White H.L.H.Wong E.Worcester D.R.Wu F.L.Wu Q.Wu W.J.Wu D.M.Xia z.Q.Xie z.z.Xing H.K.Xu J.L.Xu T.Xu T.Xue C.G.Yang L.Yang Y.z.Yang H.F.Yao M.Ye M.Yeh b.L.Young H.z.Yu z.Y.Yu b.b.Yue V.zavadskyi S.zeng Y.zeng L.zhan C.zhang F.Y.zhang H.H.zhang J.W.zhang Q.M.zhang S.Q.zhang X.T.zhang Y.M.zhang Y.X.zhang Y.Y.zhang z.J.zhang z.P.zhang z.Y.zhang J.zhao R.z.zhao L.zhou H.L.zhuang J.H.zou Institute of Modern Physics East China University of Science and TechnologyShanghai 200337 University of Wisconsin MadisonWisconsin 53706 brookhaven National Laboratory UptonNew York 11973 Department of Physics Nnational Taiwan UniversityTaipei Institute of High Energy Physics Beijing 100049 National United University Miao-Li Department of Engineering Physics Tsinghua UniversityBeijing 100048 Shenzhen University Shenzhen 518061 Sun Yat-Sen(zhongshan)University Guangzhou 510275 North China Electric Power University Beijing 102206 Chinese University of Hong Kong Hongkong 999077 Siena College LoudonvilleNew York 12211 Department of Physics and Astronomy University of CaliforniaIrvineCalifornia 92697 University of Science and Technology of China Hefei 230022 Charles University Faculty of Mathematics and PhysicsPrague Joint Institute for Nuclear Research DubnaMoscow Region Department of Physics University of Illinois at Urbana-ChampaignUrbanaIllinois 61801 Lawrence berkeley National Laboratory BerkeleyCalifornia 94720 Department of Physics Illinois Institute of TechnologyChicagoIllinois 60616 beijing Normal University Beijing 100875 Department of Nuclear Science and Technology School of Energy and Power EngineeringXi'an Jiaotong UniversityXi'an 710049 Wright Laboratory and Department of Physics Yale UniversityNew HavenConnecticut 06520 China Institute of Atomic Energy Beijing 102413 Shandong University Jinan 250002 Guangxi University No.100 Daxue East RoadNanning 530004 Center for Neutrino Physics Virginia TechBlacksburgVirginia 24061 Institute of Physics NCTUHsinchu Department of Physics University of CincinnatiCincinnatiOhio 45221 Department of Physics College of Science and TechnologyTemple UniversityPhiladelphiaPennsylvania 19122 Dongguan University of Technology Dongguan 523808 Department of Physics University of CaliforniaBerkeleyCalifornia 94720 Department of Physics The University of Hong KongPokfulamHongkong 999077 School of Physics Nankai UniversityTianjin 300071 Department o

The prediction of reactor antineutrino spectra will play a crucial role as reactor experiments enter the precision *** positron energy spectrum of 3.5 million antineutrino inverse beta decay reactions observed by the Daya bay experiment,in combination with the fission rates of fissile isotopes in the reactor,is used to extract the positron energy spectra resulting from the fission of specific *** information can be used to produce a precise,data-based prediction of the antineutrino energy spectrum in other reactor antineutrino experiments with different fission fractions than Daya *** positron energy spectra are unfolded to obtain the antineutrino energy spectra by removing the contribution from detector response with the Wiener-SVD unfolding *** results are obtained with other unfolding methods.A technique to construct a data-based prediction of the reactor antineutrino energy spectrum is proposed and *** the reactor fission fractions,the technique can predict the energy spectrum to a 2%*** addition,we illustrate how to perform a rigorous comparison between the unfolded antineutrino spectrum and a theoretical model prediction that avoids the input model bias of the unfolding method.

关键词： reactor antineutrino energy spectrum Daya bay application

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Evidence for the decays of ∧_c^+→∑^+η and ∑^+η’

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Chinese Physics C 2019年第8期43卷 15-23页

作者： M.Ablikim F.F.An Q.An Y.bai Y.ban H.Cai X.Cai G.F.Cao J.F.Chang G.Chen H.S.Chen J.C.Chen M.L.Chen P.L.Chen S.J.Chen Y.b.Chen W.Cheng H.LDai J.P.Dai z.Y.Deng Y.Ding C.Dong J.Dong L.Y.Dong M.Y.Dong z.L.Dou S.X.Du P.F.Duan J.z.Fan J.Fang S.S.Fang Y.Fang C.Q.Feng C.D.Fu Y.Fu Q.Gao X.L.Gao Y.Gao Y.G.Gao z.Gao L.Gong W.X.Gong L.M.Gu M.H.Gu Y.T.Gu A.Q.Guo L.b.Guo R.P.Guo Y.P.Guo S.Han X.Q.Hao K.L.He Y.K.Heng z.L.Hou H.M.Hu J.F.Hu T.Hu Y.Hu G.S.Huang J.S.Huang X.T.Huang X.z.Huang z.L.Huang Q.Ji Q.P.Ji X.b.Ji X.L.Ji X.S.Jiang X.Y.Jiang J.b.Jiao z.Jiao D.P.Jin S.Jin Y.Jin X.S.Kang b.C.Ke C.li Cheng li D.M.li F.li F.Y.li G.li H.b.li H.J.li J.C.li J.W.li Ke li Lei li P.L.li P.R.li Q.Y.li T.li W.D.li W.G.li X.L.li X.N. li X.Q.li z.b.li H.liang Y.F.liang Y.T.liang G.R.liao L.z.liao C.X.lin D.X.lin b.liu b.J.liu C.X.liu D.liu D.Y.liu F.H.liu Fang liu Feng liu H.b.liu H.L.liu H.M.liu Huanhuan liu Huihui liu J.b.liu J.Y.liu K.liu K.Y.liu Ke liu Q.liu S.b.liu X.liu Y.b.liu z.A.liu zhiqing liu Y.F.Long X.C.Lou H.J.Lu J.D.Lu J.G.Lu Y.Lu Y.P.Lu C.L.Luo M.X.Luo T.Luo X.L.Luo X.R.Lyu F.C.Ma H.L.Ma L.L.Ma M.M.Ma Q.M.Ma X.N.Ma X.X.Ma X.Y.Ma Y.M.Ma Y.J.Mao z.P.Mao z.X.Meng J.Min T.J.Min X.H.Mo Y.J.Mo z.Ning S.L.Niu S.L.Olsen Q.Ouyang Y.Pan H.P.Peng J.L.Ping R.G.Ping H.R.Qi M.Qi T.Y.Qi S.Qian C.F.Qiao N.Qin z.H.Qin J.F.Qiu S.Q.Qu G.Rong W.Shan X.Y.Shan M.Shao C.P. Shen P.X.Shen X.Y.Shen H.Y.Sheng X.Shi J.J.Song X.Y.Song G.X.Sun J.F.Sun L.Sun S.S.Sun X.H.Sun Y.J.Sun Y.K.Sun Y.z.Sun z.J.Sun z.T.Sun Y.T.Tan C.J.Tang G.Y.Tang X.Tang b.Wang b.L.Wang C.W.Wang D.Y.Wang Dan Wang K.Wang L.L.Wang L.S.Wang M.Wang Meng Wang P.Wang P.L.Wang W.P.Wang X.F.Wang Y.Wang Y.F.Wang z.Wang z.G.Wang z.Y.Wang zongyuan Wang D.H.Wei S.P.Wen L.H.Wu L.J.Wu z.Wu L.Xia Y.Xia D.Xiao Y.J.Xiao z.J.Xiao Y.G.Xie Y.H.Xie X.A.Xiong Q.L.Xiu G.F.Xu J.J.Xu L.Xu Q.J.Xu Q.N.Xu X.P.Xu F.Yan L.Yan w.b.Yan W.C.Yan Y.H.Yan H.J.Yang H.X.Yang L.Yang S.L.Yang Y.H.Yang Y.X.Yang Yifan Yang z.Q.Yang M.Ye M.H.Ye J.H.Yin z.Y.You b.X.Yu C.X.Yu J.S.Yu C.z.Yuan Y.Yuan Y.zeng b.X.zhang b.Y.zhang Institute of High Energy Physics G.I.budker Institute of Nuclear Physics Sb RAS(bINP) the Novosibirsk State University Helmholtz Institute Mainz bochum Ruhr-University University of Turin INFN State Key Laboratory of Particle Detection and Electronics University of Science and Technology of China Southeast University Joint Institute for Nuclear Research INFN Laboratori Nazionali di Frascati Peking University Institute of Physics and Technology Indiana University Bloomington Carnegie Mellon University Johannes Gutenberg University of Mainz INFN Sezione di Ferrara Wuhan University Ankara University University of Chinese Academy of Sciences Istanbul bilgi University the Moscow Institute of Physics and Technology the Functional Electronics Laboratory Tomsk State University University of South China Nanjing University Shanghai Jiao Tong University Key Laboratory for Particle Physics Astrophysics and CosmologyMinistry of EducationShanghai Key Laboratory for Particle Physics and CosmologyInstitute of Nuclear and Particle Physics liaoning University Nankai University zhengzhou University Tsinghua University University of Ferrara University of Eastern Piedmont Central China Normal University University of Minnesota Minneapolis GSI Helmholtzcentre for Heavy Ion Research GmbH Guangxi University Nanjing Normal University KVI-CART University of Groningen Henan Normal University University of Hawaii Honolulu Shandong University University of the Punjab University of Muenster Uppsala University Huangshan College University of Jinan Justus-liebig-Universitaet Giessen II.Physikalisches Institut Istanbul Arel University Soochow University beijing Institute of Petrochemical Technology China Center of Advanced Science and Technology Sun Yat-Sen University Sichuan University Guangxi Normal University Indian Institute of Technology Madras Shanxi University Henan University of Science and Technology Lanzhou University zhejiang University Fudan University Key Laboratory of Nuclear Physics and Ion-beam Application(MOE)and Institute of

We study the hadronic decays of ∧c+ to the final states ∑+η and ∑+η’,using an e+e-annihilation data sample of 567 pb-1 taken at a center-of-mass energy of 4.6 GeV with the bESIII detector at the bEPCⅡ *** find evidence for the decays ∧c+→∑+η and ∑+η’ with statistical significance of 2.5σ and 3.2σ,*** to the reference decays ∧c+→∑+π0 and ∑+ω,we obtain the ratios of the branching fractions■and ■to be 0.35±0.16±0.02 and 0.86±0.34±0.04,*** upper limits at the 90% confidence level are set to be■and■.Using bESIII measurements of the branching fractions of the reference decays,we determine b（∧c+→∑+η）=（0.41±0.19±0.05）%（b（∧c+→∑+η’）=（1.34±0.53 ±0.19）%（btained branching fraction of ∧c+→∑+η is consistent with the previous measurement,and the branching fraction of ∧c+→∑+η’ is measured for the first time.

关键词： charmed baryon ∧c^+ decays branching fractions

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影像组学标签:术前鉴别以毛玻璃结节为表现的肺侵袭性腺癌的生物标志物

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国际医学放射学杂志 2019年第2期42卷 253-253页

作者： L.Fan M.J.Fang z.b.li W.T.Tu S.P.Wang W.F.Chen 杨凯(译) 赵世华(校) Department of Radiology Changzheng HospitalSecond Military Medical UniversityNo.415 Fengyang RoadShanghai 200003China 不详

目的识别能够术前鉴别以毛玻璃结节为表现的肺侵袭性腺癌和非侵袭性病变的影像组学特征。方法回顾性纳入160例经病理证实的肺腺癌。从术前平扫CT影像中提取影像组学特征构建影像组学标签。

关键词：毛玻璃肺腺癌侵袭性生物标志物

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Ti^(3+)/Ti^(4+)and Co^(2+)/Co^(3+)redox couples in Ce-doped Co-Ce/TiO2 for enhancing photothermocatalytic toluene oxidation

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Journal of Environmental Sciences 2025年第3期149卷 164-176页

作者： Guanghui li Xiaolan li Xinhui Hao Qiang li Meng zhang Hongpeng Jia Xiamen Key Laboratory of Materials for Gaseous Pollutant Control Institute of Urban EnvironmentChinese Academy of SciencesXiamen 361021China Key Laboratory of Urban Pollutant Conversion Institute of Urban EnvironmentChinese Academy of SciencesXiamen 361021China CAS Center for Excellence in Regional Atmospheric Environment Institute of Urban EnvironmentChinese Academy of SciencesXiamen 361021China University of Chinese Academy of Sciences Beijing 100049China

Cerium and cobalt loaded Co-Ce/TiO_(2)catalyst prepared by impregnation method was investigated for photothermal catalytic toluene *** on catalyst characterizations(XPS,EPR and H2-TPR),redox cycle between Co and TiO_(2)(Co^(2+)+Ti^(4+)↔Co^(3+)+Ti^(3+))results in the formation of Co^(3+),Ti^(3+)and oxygen vacancies,which play important roles in toluene catalytic oxidation *** introduction of Ce brings in the dual redox cycles(Co^(2+)+Ti^(4+)↔Co^(3+)+Ti^(3+),Co^(2+)+Ce4+↔Co^(3+)+Ce3+),further promoting the elevation of reaction sites *** full spectrum irradiation with light intensity of 580mW/cm^(2),Co-Ce/TiO_(2)catalyst achieved 96%of toluene conversion and 73%of CO_(2)yield,obviously higher than Co/P25 and Co/TiO_(2).Co-Ce/TiO_(2)efficiently maintains 10-hour stability test under water vapor conditions and exhibits better photothermal catalytic performance than counterparts under different wavelengths *** catalytic reaction displays improved activities compared with thermal catalysis,which is attributed to the promotional effect of light including photocatalysis and light activation of reactive oxygen species.

关键词： Photothermal catalysis Redox cycle Oxygen vacancy VOCs Titanium dioxide

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Damage analysis caused by ^(60)Co ions in functionally graded materials

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Defence Technology(防务技术) 2025年第2期44卷 248-256页

作者： zübeyde Özkan Ugur Gökmen Sema bilge Ocak Department of Advanced Technologies Graduate School of Natural and Applied SciencesGazi UniversityAnkara06560Turkiye Department of Metallurgical and Materials Engineering Faculty of TechnologyGazi UniversityAnkara 06560Turkiye basic and Engineering Sciences Central Laboratory Application and Research Center Gazi UniversityAnkara 06560Turkiye

Functionally graded composite/hybrid materials(FGCM/FGHCM)were produced by adding b_(4)C,TiO_(2),and b_(4)C+TiO_(2)ceramic materials at various ratios(0-50%)into the AA6082 *** analysis of the damage caused by^(60) ions'(1.173-1.1332 MeV)on the material was examined using the SRIM/TRIM Monte Carlo simulation *** the simulation,the following data regarding the atoms of the target materials were obtained:ion distribution,target ionization,total displacements,surface binding energy,lattice binding energy,and displacement *** the studied four materials,the one with the highest ion range value was found to be AA6082 with ***_(2)was found to be the reinforcement material that reduced the ion range the most in the *** to its high binding energy,b_(4)C reinforced AA6082+(0-50%)b_(4)C FGCM was found to have the least vacancy with 4782/ion.

关键词： SRIM/TRIM Damage analysis AA6082 ^(60)Co ion

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Observation of e^+e^-→D_s^+■^((*)0)K^- and study of the P-wave D_s mesons

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Chinese Physics C 2019年第3期43卷 5-16页

作者： M.Ablikim M.N.Achasov S.Ahmed M.Albrecht M.Alekseev A.Amoroso F.F.An Q.An Y.bai O.bakina R.baldini Ferroli Y.ban K.begzsuren D.W.bennett J.V.bennett N.berger M.bertani D.bettoni F.bianchi I.boyko R.A.briere H.Cai X.Cai A.Calcaterra G.F.Cao S.A.Cetin J.Chai J.F.Chang W.L.Chang G.Chelkov G.Chen H.S.Chen J.C.Chen M.L.Chen S.J.Chen Y.b.Chen W.S.Cheng G.Cibinetto F.Cossio H.L.Dai J.P.Dai A.Dbeyssi D.Dedovich z.Y.Deng A.Denig I.Denysenko M.Destefanis F.De Mori Y.Ding C.Dong J.Dong L.Y.Dong M.Y.Dong z.L.Dou S.X.Du J.z.Fan J.Fang S.S.Fang Y.Fang R.Farinelli L.Fava F.Feldbauer G.Felici C.Q.Feng M.Fritsch C.D.Fu Y.Fu Q.Gao X.L.Gao Y.N.Gao Y.G.Gao z.Gao b.Garillon I.Garzia A.Gilman K.Goetzen L.Gong W.X.Gong W.Gradl M.Greco L.M.Gu M.H.Gu S.Gu Y.T.Gu A.Q.Guo L.b.Guo R.P.Guo Y.P.Guo A.Guskov z.Haddadi S.Han X.Q.Hao F.A.Harris K.L.He F.H.Heinsius T.Held Y.K.Heng z.L.Hou H.M.Hu J.F.Hu T.Hu Y.Hu G.S.Huang J.S.Huang X.T.Huang X.z.Huang z.L.Huang N.Huesken T.Hussain W.Ikegami Andersson W.Imoehl M.Irshad Q.Ji Q.P.Ji X.b.Ji X.L.Ji H.L.Jiang X.S.Jiang X.Y.Jiang J.b.Jiao z.Jiao D.P.Jin S.Jin Y.Jin T.Johansson N.Kalantar-Nayestanaki X.S.Kang M.Kavatsyuk b.C.Ke I.K.Keshk T.Khan A.Khoukaz P.Kiese R.Kiuchi R.Kliemt L.Koch O.b.Kolcu b.Kopf M.Kuemmel M.Kuessner A.Kupsc M.Kurth W.Kühn J.S.Lange P.Larin L.Lavezzi H.Leithoff C.li Cheng li D.M.li F.li F.Y.li G.li H.b.li H.J.li J.C.li J.W.li Ke li L.K.li Lei li P.L.li P.R.li Q.Y.li W.D.li W.G.li X.L.li X.N.li X.Q.li z.b.li H.liang Y.F.liang Y.T.liang G.R.liao L.z.liao J.libby C.X.lin D.X.lin b.liu b.J.liu C.X.liu D.liu D.Y.liu F.H.liu Fang liu Feng liu H.b.liu H.L liu H.M.liu Huanhuan liu Huihui liu J.b.liu J.Y.liu K.Y.liu Kai liu Ke liu Q.liu S.b.liu X.liu Y.b.liu z.A.liu zhiqing liu Y.F.Long X.C.Lou H.J.Lu J.D.Lu J.G.Lu Y.Lu Y.P.Lu C.L.Luo M.X.Luo P.W.Luo T.Luo X.L.Luo S.Lusso X.R.Lyu F.C.Ma H.L.Ma L.L.Ma M.M.Ma Q.M.Ma X.N.Ma X.X.Ma X.Y.Ma Y.M.Ma F.E.Maas M.Maggiora S.Maldaner Q.A.Malik A.Mangoni Y.J.Mao z.P.Mao S.Marcello z.X.Meng J.G.Messchendorp G.Mezzadri J.Min T.J.Min R.E.Mitchell X.H.Mo Y Institute of High Energy Physics Beijing 100049China beihang University Beijing 100191China beijing Institute of Petrochemical Technology Beijing 102617China bochum Ruhr-University D-44780 BochumGermany Carnegie Mellon University PittsburghPennsylvania 15213USA Central China Normal University Wuhan 430079China China Center of Advanced Science and Technology Beijing 100190China COMSATS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan Fudan University Shanghai 200443China G.I.budker Institute of Nuclear Physics Sb RAS(bINP) Novosibirsk 630090Russia GSI Helmholtzcentre for Heavy Ion Research GmbH D-64291 DarmstadtGermany Guangxi Normal University Guilin 541004China Guangxi University Nanning 530004China Hangzhou Normal University Hangzhou 310036China Helmholtz Institute Mainz Johann-Joachim-Becher-Weg 45D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University of Science and Technology Luoyang 471003China Huangshan College Huangshan 245000China Hunan Normal University Changsha 410081China Hunan University Changsha 410082China Indian Institute of Technology Madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INFN Laboratori Nazionali di Frascati I-00044FrascatiItaly INFN Sezione di Ferrara I-44122FerraraItaly Institute of Physics and Technology Peace Ave.54BUlaanbaatar 13330Mongolia Johannes Gutenberg University of Mainz Johann-Joachim-Becher-Weg 45D-55099 MainzGermany Joint Institute for Nuclear Research 141980 DubnaMoscow regionRussia Justus-liebig-Universitaet Giessen II.Physikalisches InstitutHeinrich-Buff-Ring 16D-35392 GiessenGermany KVI-CART University of GroningenNL-9747 AA GroningenThe Netherlands Lanzhou University Lanzhou 730000China liaoning University Shenyang 110036China Nanjing Normal University Nanjing 210023China Nanjing University Nanjing 210093China Nankai University Tianjin 300071China Peking University Beijing 100871China Shandong University Jinan 250100China Shanghai

Studies of e^+e~→D_s^+■^((*)0)K^-and the P-wave charmed-strange mesons are performed based on an e^+e^-collision data sample corresponding to an integrated luminosity of 567 pb^(-1) collected with the bESIII detector at s^(1/2)=4.600 GeV. The processes of e^+e^-→D_s^+■^(*0)K^- and D_s^+■~0K^- are observed for the first time and are found to be dominated by the modes D_s^+D_(s1)(2536)^-and D_s^+D_(s2)~*(2573)^-, respectively. The born cross sections are measured to be σ~b(e^+e^-→D_s^+■^(*0)K^-) =(10.1±2.3±0.8) pb and σ~b(e^+e^-→D_s^+■~0K^-) =(19.4±2.3± 1.6) pb, and the products of born cross section and the decay branching fraction are measured to be σ~b(e^+e^-→D_s^+D_(s1)(2536)^-+c.c.)·b(D_(s1)(2536)^-→■^(*0)K^-)=(7.5±1.8±0.7) pb and σ~b(e^+e^-→D_s^+D_(s2)~*(2573)^-+ c.c.)·b(D_(s2)~*(2573)^-→■~0 K^-)=(19.7 ± 2.9 ±2.0) pb. For the D_(s1)(2536)^-and D_(s2)~*(2573)^-mesons, the masses and widths are measured to be M(D_(s1)(2536)^-)=(2537.7±0.5 ±3.1) MeV/c2, Γ(D_(s1)(2536)^-) =(1.7 ±1.2 ±0.6)MeV, and M(D_(s2)~*(2573)^-)=(2570.7±2.0 ±1.7) MeV/c^2, Γ(D_(s2)~*(2573)^-)=(17.2 ±3.6 ±1.1) MeV. The spin-parity of the D_(s2)~*(2573)^-meson is determined to be J^p= 2^+. In addition, the processes e^+e^-→D_s^+■^((*)0)K^-are searched for using the data samples taken at four(two) center-of-mass energies between 4.416(4.527) and 4.575 GeV, and upper limits at the 90% confidence level on the cross sections are determined.

关键词： cross section P-wave D_s mesons resonance parameters spin-parity bESIII

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Constraints on holographic QCD phase transitions from PTA observations

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Science China(Physics,Mechanics & Astronomy) 2025年第1期68卷 67-74页

作者： Song He li li Sai Wang Shao-Jiang Wang Center for Theoretical Physics and College of Physics Jilin UniversityChangchun 130012China School of Physical Science and Technology Ningbo UniversityNingbo 315211China CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China School of Fundamental Physics and Mathematical Sciences Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of Sciences(UCAS)Hangzhou 310024China Theoretical Physics Division Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China School of Physical Sciences University of Chinese Academy of Sciences(UCAS)Beijing 100049China Max Planck Institute for Gravitational Physics(Albert Einstein Institute) Am Muhlenberg 1Golm 14476Germany

The underlying physics of QCD phase transition in the early Universe remains largely unknown due to its strong-coupling nature during the quark-gluon plasma/hadron gas transition,yet a holographic model has been proposed to quantitatively fit the lattice QCD data while with its duration of the first-order phase transition(FoPT)left *** specific baryon chemical poten-tial,the first-order QCD phase transition agrees with the observational constraint of baryon ***,therefore,provides a scenario for phase transition gravitational waves(GWs)within the standard model of particle *** these background GWs could contribute dominantly to the recently claimed common-spectrum red noise from pulsar timing array(PTA)observations,the duration of this FoPT can be well constrained,and the associated primordial black holes are still allowed by current observations.

关键词： pulsar timing array QCD phase transition gravitational waves primordial black holes

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