检索结果-南通市图书馆

The role of bacterial signaling networks in antibiotics response and resistance regulation

在线全文

学校读者我要写书评

暂无评论

Marine life Science & Technology 2022年第2期4卷 163-178页

作者： yuying li Tao Feng Yan Wang College of Marine life Sciences Ocean University of ChinaQingdao266003China Institute of Evolution and Marine Biodiversity Ocean University of ChinaQingdao266003China Laboratory for Marine Ecology and Environmental Science National Laboratory for Marine Science and Technology(Qingdao)Qingdao266071China

Excessive use of antibiotics poses a threat to public health and the *** ecosystems,such as the marine environment,antibiotic contamination has led to an increase in bacterial ***,the study of bacterial response to antibiotics and the regulation of resistance formation have become an important research ***,the processes related to antibiotic responses and resistance regulation have mainly included the activation of efflux pumps,mutation of antibiotic targets,production of biofilms,and production of inactivated or passivation *** recent years,studies have shown that bacterial signaling networks can affect antibiotic responses and resistance *** systems mostly alter resistance by regulating biofilms,efflux pumps,and mobile genetic *** we provide an overview of how bacterial intraspecific and interspecific signaling networks affect the response to environmental *** doing so,this review provides theoretical support for inhibiting bacterial antibiotic resistance and alleviating health and ecological problems caused by antibiotic contamination.

关键词： Bacterial antibiotic resistance AHL AI-2 AIP Indole DSF

Identifying Industrial Control Equipment Based on Rule Matching and Machine Learning

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2023年第10期137卷 577-605页

作者： Yuhao Wang yuying li Yanbin Sun Yu Jiang Cyberspace Institute of Advanced Technology(CIAT) Guangzhou UniversityGuangzhou510006China

To identify industrial control equipment is often a key step in network mapping,categorizing network resources,and attack *** example,if vulnerable equipment or devices can be discovered in advance and the attack path canbe cut off,security threats canbe effectively avoided and the stable operationof the Internet canbe *** existing rule-matching method for equipment identification has limitations such as relying on experience and low *** paper proposes an industrial control device identification method based on PCA-Adaboost,which integrates rule matching and machine *** first build a rule base from network data collection and then use single andmulti-protocol rule-matchingmethods to identify the type of industrial control ***,we utilize PCA-Adaboost to identify unlabeled *** experimental results show that the recognition rate of this method is better than that of the traditional Nmap device recognitionmethod and the device recognition accuracy rate reaches 99%.The evaluation effect of the test data set is significantly enhanced.

关键词： Network mapping network resource industrial control equipment identification

Empirical Evidence of the Leverage Effect in a Stochastic Volatility Model： A Realized Volatility Approach

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Economics in China-Selected Publications from Chinese Universities 2012年第1期7卷 22-43页

作者： Dinghai Xu yuying li Department of Economics University of Waterloo Waterloo ON N2L 3G1 Canada School of Computer Science University of Waterloo Waterloo ON N2L 3G1 Canada

Increasing attention has been focused on the analysis of the realized volatil- ity, which can be treated as a proxy for the true volatility. In this paper, we study the potential use of the realized volatility as a proxy in a stochastic volatility model estimation. We estimate the leveraged stochastic volatility model using the realized volatility computed from five popular methods across six sampling-frequency transaction data （from 1-min to 60- min） based on the trust region method. Availability of the realized volatility allows us to estimate the model parameters via the MLE and thus avoids computational challenge in the high dimensional integration. Six stock indices are considered in the empirical investigation. We discover some consistent findings and interesting patterns from the empirical results. In general, the significant leverage effect is consistently detected at each sampling frequency and the volatility persistence becomes weaker at the lower sampling frequency.

关键词： realized volatility stochastic volatility model leverage effect high frequency data MLE trust-region method

Role of D-aspartate on biosynthesis,racemization,and potential functions:A mini-review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Animal Nutrition 2018年第3期4卷 311-315页

作者： yuying li Hui Han Jie Yin Tiejun li Yulong Yin Key Laboratory of Agro-Ecological Processes in Subtropical Region National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry ProductionHunan Provincial Engineering Research Center for Healthy Livestock and Poultry ProductionScientific Observing and Experimental Station of Animal Nutrition and Feed Science in South-CentralMinistry of AgricultureInstitute of Subtropical AgricultureChinese Academy of SciencesChangsha 410125China University of Chinese Academy of Sciences Beijing 100039China Hunan Co-Innovation Center of Animal Production Safety Changsha 410128China

D-aspartate, a natural and endogenous amino acid, widely exists in animal tissues and can be synthesized through aspartate racemase and transformed by D-aspartate oxidase(DDO). D-aspartate mainly serves as a neurotransmitter and has been demonstrated to exhibit various physiological functions,including nutritional potential, regulation on reproduction and hormone biology, and neuron *** article mainly reviews the synthesis, racemization, and physiological functions of D-aspartate with emphasis on the potential in diseases.

关键词： D-aspartate Biosynthesis Racemization Nutrition Functions

Circularly polarized luminescence switch based on a photochromic europium(Ⅲ) helicate derived coordination polymer

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第2期35卷 272-277页

作者： Mei li Yanyan Zhou Jingya li Wenru Huang Zhiwei Yao yuying li Ting Gao Pengfei Yan Hongfeng li Key Laboratory of Functional Inorganic Material Chemistry Ministry of EducationSchool of Chemistry and Materials ScienceHeilongjiang UniversityHarbin 150080China State Key Laboratory of Baiyunobo Rare Earth Resource Researches and Comprehensive Utilization Institution Baotou 014030China

Chiroptical switches based on circularly polarized luminescence(CPL)have shown the promising applications in advanced information ***,a pair of lanthanide coordination polymer enantiomers[Eu_(2)(L^(R))_(3)(BTFPO)_(2)]_(n) and[Eu_(2)(L^(S))_(3)(BTFPO)_(2)]_(n) with light-regulated CPL property are designed,which are assembled by a chiral binuclear triple-stranded Eu^(3+) helicates[Eu_(2)(L^(R/S))_(3)]coordinated with two photochromic triphenylphosphine oxides(BTFPO).Upon the alternative UV and 526 nm light irradiation,the complexes show the reversible photochromism,PL and CPL ***,the luminescence dissymmetry factor,g lum of ^(5)D_(0)→^(7)F_(1)(591 nm)transition shows an obvious increase from 0.19 to 0.29 before and after 275 nm light ***,the emission from Eu^(3+) center is not completely quenched in closed-ring state due to the low photocyclization(Ф_(o-c))quantum yield of the *** partial maintenance of emissive intensity is of essential importance for the monitor of CPL *** importantly,the CPL photo-switching property of the complexes in solid hybrid film is maintained,and still displays the enhanced CPL emission in photostationary ***,the potential applications of the doping film in logic gate and anti-counterfeiting were investigated.

关键词： Chiroptical switches Coordination polymer CPL Anti-counterfeiting Logic gate

替罗非班在急性脑梗死静脉溶栓后患者中的应用进展

在线全文

学校读者我要写书评

暂无评论

中国实用神经疾病杂志 2025年第1期28卷 124-128页

作者：陈英道李育英张岐平广西医科大学第七附属医院梧州市工人医院广西梧州543000

急性脑梗死(ACI)静脉溶栓治疗后需继续接受抗血小板治疗,以预防梗死复发和其他心脑血管事件。替罗非班是较常用的抗血小板药物,在ACI患者中的应用愈加广泛,具有抗血小板聚集、抗炎等作用,能够减少血栓栓塞事件,且未增加出血风险。现阶... 详细信息

急性脑梗死(ACI)静脉溶栓治疗后需继续接受抗血小板治疗,以预防梗死复发和其他心脑血管事件。替罗非班是较常用的抗血小板药物,在ACI患者中的应用愈加广泛,具有抗血小板聚集、抗炎等作用,能够减少血栓栓塞事件,且未增加出血风险。现阶段替罗非班在ACI静脉溶栓治疗后的应用已较为成熟,联合双抗血小板(DAPT)、肝素等药物均具有安全有效的优势,且低剂量的替罗非班安全性更高。以替罗非班为主的综合抗栓方案或可成为ACI静脉溶栓治疗后患者的优先选择。

关键词：急性脑梗死静脉溶栓替罗非班抗血小板聚集抗炎

Two-component system GacS/GacA,a global response regulator of bacterial physiological behaviors

在线全文

学校读者我要写书评

暂无评论

Engineering Microbiology 2023年第1期3卷 37-48页

作者： Huihui Song yuying li Yan Wang College of Marine life Sciences Ocean University of ChinaQingdao 266003China Laboratory for Marine Ecology and Environmental Science Qingdao National Laboratory for Marine Science and TechnologyQingdao 266071China Institute of Evolution and Marine Biodiversity Ocean University of ChinaQingdao 266003China

The signal transduction system of microorganisms helps them adapt to changes in their complex living ***-component system(TCS)is a representative signal transduction system that plays a crucial role in regulating cellular communication and secondary *** Gram-negative bacteria,an unorthodox TCS consist-ing of histidine kinase protein GacS(initially called LemA)and response regulatory protein GacA is *** mainly regulates various physiological activities and behaviors of bacteria,such as quorum sensing,secondary metabolism,biofilm formation and motility,through the Gac/Rsm(Regulator of secondary metabolism)signaling cascade *** global regulatory ability of GacS/GacA in cell physiological activities makes it a potential research entry point for developing natural products and addressing antibiotic *** this review,we summarize the progress of research on GacS/GacA from various perspectives,including the reaction mechanism,related regulatory pathways,main functions and GacS/GacA-mediated ***,this review will facilitate further research on GacS/GacA and promote its application in regulating secondary metabolism and as a therapeutic target.

关键词： GacS/GacA Two-component system Signaling regulatory network Secondary metabolite Antibiotic resistance

Plants affect the horizontal transmission of a new densovirus infecting the green peach aphid Myzus persicae by modulating honeydew production

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Insect Science 2024年第1期31卷 236-254页

作者： Ya Guo Yani Zhao Yang Yang Yahong Zhang yuying li Honggang Tian Tong-Xian liu Zhaofei li State Key Laboratory of Crop Stress Biology for Arid Areas Key Laboratory of Northwest Loess Plateau Crop Pest Management of Ministry of AgricultureCollege of Plant ProtectionNorthwest A&F UniversityYanglingChina Institute of Entomology and Institute of Plant Health&Medicine Guizhou UniversityGuiyangChina

In a tritrophic context of plant-insect-entomopathogen,plants play important roles in modulating the interaction of insects and their pathogenic ***,the influence of plants on the transmission of insect viruses has been mainly studied on baculoviruses and some RNA viruses,whereas the impact of plants on other insect viruses is largely ***,we identified a new densovirus infecting the green peach aphid Myzus persicae and tested whether and how host plants influence the transmission of the aphid *** complete single-stranded DNA genome of the virus,*** densovirus 2,is 5727 nt and contains inverted terminal *** and phylogenetic analysis indicated that the virus was distinct from other a few identified aphid *** virus abundance was detected highly in the intestinal tract of aphids,compared with the lower level of it in other tissues including head,embryo,and *** and pepper plants had no obvious effect on the vertical transmission and saliva-mediated horizontal transmission of the ***,the honeydew-mediated horizontal transmission among aphids highly depended on host plants(65%on cabbages versus 17%on peppers).Although the virus concentration in the honeydew produced by aphids between 2 plants was similar,the honeydew production of the infected aphids reared on peppers was dramatically *** together,our results provide evidence that plants influence the horizontal transmission of a new densovirus in an aphid population by modulating honeydew secretion of aphids,suggesting plants may manipulate the spread of an aphid-pathogenic densovirus in nature.

关键词： aphids densovirus host plants MpDV2 Myzus persicae transmission

Effects of β-ecdysone and polypodine-B on moulting and growth of prawn, Penaeus orientalis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Oceanologica Sinica 1992年第2期11卷 231-235页

作者： Luo Rixiang, Wang yuying and li Guangyou

Effects of the mixture of β-ecdysone and polypodine -B (2 : 1 W/W) on the moulting and growth of prawn, Penaeus orientaliss were studied in laboratory by rearing the animal with the added compound diets. The results showed that the addition of the moulting hormone (M. H) mixture to compound diets, from 1. 33× 10-6 to 30×10-6, could increase moulting activity and growth rate of the prawn to different extents, among which the 5. 33× 10-6-10. 67×10-6addition had statistically significant effects. However, 60 × 10-6 added diets caused moulting and growth inhibitions and cuticle thickening. The analyses of protein, water and ash contents of the prawn showed no remarkable differences between hormone dosed animals and the control.

关键词： Effects of Penaeus orientalis ecdysone and polypodine-B on moulting and growth of prawn