检索结果-南通市图书馆

Transdermal drug delivery systems in diabetes management: A review

Asian Journal of Pharmaceutical Sciences 2020年第1期15卷 13-25页

作者： Li Ching ng Manish Gupta School of Pharmacy Monash University MalaysiaBandar Sunway 47500Malaysia Faculty of Pharmacy DIT UniversityDehradun 248009India

Diabetes mellitus is a chronic disease in which there is an insufficient production of insulin by the pancreas, or the insulin produced is unable to be utilized effectively by the body. Diabetes affects more than 415 million people globally and is estimated to strike about 642 million people in 2040. The WHO reported that diabetes will become the seventh biggest cause of mortality in 2030. Insulin injection and oral hypoglycemic agents remain the primary treatments in diabetes management. These often present with poor patient compliance. However, over the last decade, transdermal systems in diabetes management have gained increasing attention and emerged as a potential hope in diabetes management owing to the advantages that they offer as compared to invasive injection and oral dosage forms. This review presents the recent advances and developments in transdermal research to achieve better diabetes management. Different technologies and approaches have been explored and applied to the transdermal systems to optimize diabetes management. Studies have shown that these transdermal systems demonstrate higher bioavailability compared to oral administration due to the avoidance of first-pass hepatic metabolism and a sustained drug release pattern. Besides that, transdermal systems have the advantage of reducing dosing frequency as drugs are released at a predetermined rate and control blood glucose level over a prolonged time, contributing to better patient compliance. In summary, the transdermal system is a field worth exploring due to its significant advantages over oral route in administration of antidiabetic drugs and biosensing of blood glucose level to ensure better clinical outcomes in diabetes management.

关键词： Transdermal Diabetes Antidiabetic Insulin Drug delivery system

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

ON ALGORITHMS FOR AUTOMATIC DEBLURRIng FROM A SIngLE IMAGE

引用

Journal of Computational Mathematics 2012年第1期30卷 80-100页

作者： Wei Wang Michael K.ng Department of Mathematics Tongji UniversityShanghai 200092China Centre for Mathematical Imaging and Vision and Department of Mathematics Hong Kong Baptist UniversityKowloon TongHong KongChina

In this paper, we study two variational blind deblurring models for a single linage,The first model is to use the total variation prior in both image and blur, while the second model is to use the flame based prior in both image and blur. The main contribution of this paper is to show how to employ the generalized cross validation （GCV） method efficiently and automatically to estimate the two regularization parameters associated with the priors in these two blind motion deblurring models. Our experimental results show that the visual quality of restored images by the proposed method is very good, and they are competitive with the tested existing methods. We will also demonstrate the proposed method is also very efficient.

关键词： Blind deconvolution Iterative methods Total variation Framelet Generalizedcross validation.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Aequorin-Based Luminescence Imaging Reveals Stimulus-and Tissue-Specific Ca^2＋ Dynamics in Arabidonsis Plants

引用

Molecular Plant 2013年第2期6卷 444-455页

作者： Xiaohong zh Ying Feng Gaimei Liang Na Liu Jian-Kang zhua Department of Horticulture and Landscape Architecture Purdue University West Lafayette IN 47907 USA Shanghai Center for Plant Stress Biology and Shanghai Institute of Plant Physiology and Ecology Shanghai Institutes of Biological Sciences ChineseAcademy of Sciences Shanghai 200032 China

Calcium ion is a versatile second messenger for diverse cell signaling in response to developmental and environmental cues. The specificity of Ca^2＋-mediated signaling is defined by stimulus-elicited Ca^2＋ signature and down-stream decoding processes. Here, an Aequorin-based luminescence recording system was developed for monitoring Ca^2＋ in response to various stimuli in Arabidopsis. With the simple, highly sensitive, and robust Ca^2＋ recording, this system revealed stimulus-and tissue-specific Ca^2＋ signatures in seedlings. Cellular Ca^2＋ dynamics and relationship to Aequorin-based Ca^2＋ recording were explored using a GFP-based Ca^2＋ indicator, which suggested that a synchronous cellular Ca^2＋ signal is responsible for cold-induced Ca^2＋ response in seedlings, whereas asynchronous Ca^2＋ oscillation contributes to osmotic stress-induced Ca^2＋ increase in seedlings. The optimized recording system would be a powerful tool for the iden-tification and characterization of novel components in Ca^2＋ -mediated stress-signaling pathways,

关键词： Aequorin Case12 abiotic stress calcium Arabidopsis.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

从消费税的设置目的谈我国消费税改革

引用

消费经济 2005年第2期21卷 31-33页

作者：何志静暨南大学经济学院广东广州510632

我国现行的消费税是1994年税改设置的税种,设置目的是为调节产品结构、引导消费方向、保证国家收入。经过十多年的经济发展,我国的现行消费税制在一些方面已经与其设置目的不相符,这就要求我们对现行的消费税制进行改革,更好的发挥消费... 详细信息

我国现行的消费税是1994年税改设置的税种,设置目的是为调节产品结构、引导消费方向、保证国家收入。经过十多年的经济发展,我国的现行消费税制在一些方面已经与其设置目的不相符,这就要求我们对现行的消费税制进行改革,更好的发挥消费税的特殊调节作用。

关键词：消费税设置目的改革中国课税范围税率

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Comparison between hydrogen-transfer and fluoro-transfer reactions on the microcanonical unimolecular rate constants

引用

Chinese Journal of Chemistry 1995年第5期13卷 391-395页

作者： Feng, WL zh.ng, SW Wang, Y Wu, JN Li, zh BEIJIng NORMAL UNIV DEPT CHEMBEIJING 100875PEOPLES R CHINA

The microcanonical rate constants for the hydrogen-transfer process of HCCF (reaction 7) and the fluoro-transfer process of FCCF (reaction 8) are carried out with tunneling correction and curvature correction. The results show that the tunneling effects and curvature effects on the rate constant of reaction 7 is quite different from that of reaction 8. The rate constants for different rotational states are also studied for these reactions.

关键词： microcanonical rate constant tunneling effect curvature correction

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Growth performance and scale insect infestation of Shorea leprosula in a common garden experimental plot

引用

Journal of Forestry Research 2023年第3期34卷 781-792页

作者： Chin Hong ng Kevin Kit Siong ng Soon Leong Lee Rempei Suwa Chai Ting Lee Lee Hong Tnah Forest Research Institute Malaysia 52109 KepongSelangorMalaysia Forestry Division Japan International Research Center for Agricultural SciencesTsukubaIbaraki 305‑8686Japan

Many tree planting programmes have long been initiated to increase forest cover to mitigate the effects of global climate *** planting requires careful planning at the project level,including using suitable species with favourable ***,there is a paucity of improvement data for tropical tree *** experimental common garden of Shorea leprosula was established to study traits related to growth performance which are key factors in planting *** of *** were collected from nine geographical forest *** study the effects of genetic variation,seedlings were planted in a common environment following a randomized complete block *** performance data collected 2017‒2019,one population showed the highest coefficient for relative height growth,significantly higher than most of the other ***,this population from Beserah also exhibited the lowest coefficient for scale insect *** study provides preliminary results on growth performance and susceptibility to scale insect infestation in *** and the first common garden experiment site conducted on dipterocarp *** lays a foundation for future genome-wide studies.

关键词： Root collar diameter Height Scale insect Relative growth rate Dipterocarp

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Second-order optimality conditions f or minimizing a maxfunction

引用

Science China Mathematics 2000年第7期43卷 722-733页

作者：黄力人 K.F.ng Department of Mathematics South China Normal University Guangzhou 510631 China Department of Mathematics The Chinese University of Hong KongHong KongChina Correspondence should be addressed to K.F.Ng

We study Chaney's and Ben-Tal-Zowe's second-order directional derivatives with applications in minimization problem for max-functions of the formh(x): = max {f(x, τ); τ ∈T},where T is a compact metricspace. We impr... 详细信息

关键词： max-f unction sup-type function second-order optimality condition nonsmooth optimization.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Solving sparse non-negative tensor equations： algorithms and applications

引用

Frontiers of Mathematics in China 2015年第3期10卷 649-680页

作者： Xutao LI Michael K. ng School of Computer Engineering Nanyang Technological University Singapore 639798 Singapore Centre for Mathematical Imaging and Vision and Department of MathematicsHong Kong Baptist University Hong Kong China

We study iterative methods for solving a set of sparse non-negative tensor equations （multivariate polynomial systems） arising from data mining applications such as information retrieval by query search and community discovery in multi-dimensional networks. By making use of sparse and non-negative tensor structure, we develop Jacobi and Gauss-Seidel methods for solving tensor equations. The multiplication of tensors with vectors are required at each iteration of these iterative methods, the cost per iteration depends on the number of non-zeros in the sparse tensors. We show linear convergence of the Jacobi and Gauss-Seidel methods under suitable conditions, and therefore, the set of sparse non-negative tensor equations can be solved very efficiently. Experimental results on information retrieval by query search and community discovery in multi-dimensional networks are presented to illustrate the application of tensor equations and the effectiveness of the proposed methods.

关键词： Nonnegative tensor multi-dimensional network information retrieval community iterative method multivariate polynomial equation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Magnetic properties and microstructures of SnO_2 doped Mn-Zn ferrites

引用

Rare Metals 2006年第z1期25卷 445-449页

作者： ng Foong-Kee SALE Frank R. School of Technology Tunku Abdul Rahman College PO Box 10979 50932 Kuala Lumpur West Malaysia School of Materials The University of Manchester Grosvenor Street Manchester M17HS United Kingdom

The effects of additive SnO2 (0.4wt.%), with and without SiO2 (0.02wt.%) and/or CaO (0.04wt.%), on the microstructure and magnetic properties of Mn-Zn ferrites were reported. The results reveal that SnO2 on its own increases the initial permeability (μi) slightly, but SnO2 with SiO2 and/or CaO decreases the values of μi. However, ferrites with SnO2 additions have reduced power losses. The separate contributions of hysteresis loss and eddy current loss to the total power loss show that SnO2 (with or without SiO2 and/or CaO) doping increases the hysteresis loss slightly, but SnO2 doping alone reduces the eddy current loss significantly (～14%). The additions of SiO2 or CaO further decrease the eddy current loss, and by interaction of SnO2-CaO-SiO2, the eddy current loss is reduced by more than 20%. These magnetic and microstructural effects were discussed in terms of the additive-impurity interaction, the existence of grain boundary phases, and the effective bulk and grain boundary resistivities of the ferrites.

关键词： Mn-Zn ferrites SnO2 doping magnetic properties microstructure

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

ELECTROHYDRODYNAMIC DISPERSION OF DEFORMABLE AEROSOLS IN THE PRESENCE OF AN ELECTRIC FIELD AND CHEMICAL REACTION USIng TAYLOR DISPERSION MODEL

引用

Journal of Hydrodynamics 2011年第2期23卷 247-257页

作者： RUDRAIAH N. DEVARAJU N. ng Chiu-On UGC-CAS in Fluid Mechanics Department of Mathematics Bangalore University Bangalore-560 001 India National Research Institute for Applied Mathematics (NRIAM) Bangalore-560 070 India Department of Mechanical Engineering The University of Hong Kong

Under the effects of electric field and chemical reaction, the problem of dispersion of aerosols in a poorly conducting fluid in a channel is solved analytically using the mixture theory together with a regular perturbation technique. It is shown that the aerosols are dispersed relative to a plane moving with the mean speed of atmospheric fluid as well as the mean speed of agglomeration of aerosol with a relative diffusion coefficient, called the Taylor dispersion coefficient. This coefficient is numerically computed and the results reveal that it increases with an increase in the electric number, but decreases with increasing porous parameter. The physical explanations for the phenomena are given in this article.

关键词： dispersion aerosols electrohydrodynamics mixture theory

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：