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International Journal of Ophthalmology(English edition) 2013年第2期6卷 211-215页

作者： Güngr Sobaci Riza Güngr Gkhan zge Department of Ophthalmology GATA Medical School Ankara

AIM: To determine the effect of multiple injections of ranibizumab or bevacizumab on retinal nerve fiber layer (RNFL) and intraocular pressure (IOP) in patients with age-related macular degeneration (AMD). ·METHODS: This retrospective study includes 35 eyes of 35 patients treated with intravitreal bevacizumab (IVB, 1.25mg/0.05mL) and 30 eyes of 30 patients with intravitreal ranibizumab (IVR, 0.5mg/0.05mL) who had Fast RNFL analysis (Stratus TM ); IOP measurements were taken 30 minutes and 24 hours after each injection. RESULTS: The mean ages were 68.0±7.5 and 69.1±7.7 years in the IVR and IVB groups, respectively (P =0.55). They underwent (6.3±1.9) and (5.1±1.3) injections (P = 0.07) over (13.6±2.1) and (14.05±2.6) months (P =0.45) in the IVR and IVB groups, respectively. Changes in overall and temporal RNFL thickness in IVR-treated eyes (105.3± 6.9μm and 74.4±11.2μm) were not different from those in untreated eyes in the IVR group (104.6±8.4μm and 75.1±12.6μm) (P =0.57 and P =0.41, respectively). Similarly, overall and temporal RNFL thickness in IVB-treated eyes (105.8±8.1μm and 74.5±11.8μm) were not different from those in untreated eyes in the IVB group (104.6±8μm and 74.8±12.9μm) (P=0.42 and P=0.80, respectively). The frequencies of IOP rise (P=0.60) and changes in RNFL thickness from baseline (P =0.16) were comparable between groups. CONCLUSION: Repeated intravitreal injection of ranibizumab or bevacizumab does not seem have adverse effects on RNFL thickness or IOP in wet AMD patients.

关键词： anti-VEGF bevacizumab ranibizumab retinal nerve fiber layer intraocular pressure adverse effect

De Broglie–Bohm Interpretation of Canonical Quantum Cosmology Implies Early Stages of the Universe Dominated by Radiation

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Communications in Theoretical Physics 2013年第12期60卷 691-694页

作者： Ch’ng Han Siong Shahidan Radiman School of Applied Physics Faculty of Science and Technology Universiti Kebangsaan Malaysia

The Einstein＇s genera/relativity is formulated in the Hamiltonian form for a spatia/ly Bat, isotropic and homogeneous universe. Subsequently, we perform the canonical quantization procedure to the Hamiltonian to obtain the Wheeler-DeWitt equation. Solving the Wheeler-DeWitt equation and employing the de Broglie-Bohm interpretation to the wave function of the universe, we obtain a new version of spatia/ly fiat Friedmann equation for the early universe where the scale factor of the universe is taken to be sufilcientlv small.

关键词： de Broglie-Bohm interpretation canonical quantum cosmology Friedmann equation Wheeler-DeWitt equation

ndrogen-deprivation therapy in men with metastatic rostate cancer： less may not necessarily be more

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Asian Journal of Andrology 2013年第4期15卷 445-446页

作者： Mark ng Tang Fui Mathis Grossmann Department of Medicine University of Melbourne Austin Health Heidelberg Victoria 3084 Australia and Endocrinology Austin Health Heidelberg Victoria 3084 Australia

In a pivotal phase 3 randomized con trolled trial, Hussain et al. tested thehypothesis that, with respect to survival, intermittent androgen deprivation therapy （ADT） is noninferior to continuous in men with newly diagnosed metastatic prostate cancer. While the trial findings were statis tically inconclusive, the study suggests, but does not prove, that intermittent may do more harm than good, although findings are not definitive. While outcomes of ongoing trials are awaited, the trial by Hussain et al., in conjunction with an ear lier trial in men with nonmetastatic pro state cancer by Crook et al., does provide important new guidance regarding the choice of ADT in men with androgensensitive prostate cancer. ADT is one of the most effective palliat ive therapies for patients with metastatic prostate cancer, but not without drawbacks. While not as toxic as chemotherapy, ADT carries a significant risk of morbidity, including sexual dysfunction, fatigue, ane mia, accelerated bone loss and fractures, sarcopenia, increased risk of diabetes, and possibly, of cardiovascular events.1＇2 In addition, despite an initial response rate of more than 90%, most patients develop res istance to ADT, resulting in a median sur vival of 2.53 years. Predinical data suggest that continuous use of ADT may accelerate the emergence of resistance to this therapy, and that reexposure of prostate cancer stem cells to androgens can reinduce dif ferentiation and increase their apoptotic potential.3 These ADTassociated shortcom ings, in addition to treatment expense, havespurred the development of strategies to min imize the exposure to ADT, including the use of intermittent ADT. While several smaller randomized controlled clinical trials have compared the use of intermittent with con tinuous ADT, no definitive information is available for patients with metastatic prostate cancer. To fill this evidence gap, a large mul tinational randomized controlled trial led by Hussain et al.4 was designed in

关键词： Androgen-deprivation therapy prostate

Why Does the US Face Greater Disadvantages in the Trade War with China?

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China & World Economy 2020年第2期28卷 113-122页

作者： Yew-Kwang ng School of Economics Fudan UniversityChina

The rhetoric used by President Trump regarding the trade war against China is rife with *** actual American trade deficit'with China is much lower if evaluated in the correct terms of *** deficit is mainly a result of insufficient domestic US *** addition,as the US dollar is an international currency which is being increasingly held as a result of increases in world population,income,prices and transaction intensity,Americans can benefit from having trade deficits of hundreds of billions of US dollars each *** analysis,as well as a model of the Bank of England,reveals that the trade war is not only mutually harmful but also actually hurts America more than *** Thucydides Trap is likely avoidable in the current nuclear era of assured mutual destruction and because China,facing many structural impediments,is still far behind America in technology and military powder.

关键词： Japan Sino-American relationship Thucydides Trap trade war Trump

Investigation of drinking water bacterial community through high-throughput sequencing

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Journal of Environmental Sciences 2015年第11期27卷 154-156页

作者： Tsz Wai ng Guocheng Huang Po Keung Wong School of Life Sciences The Chinese University of Hong Kong

Delivery of safe and pathogen-free drinking water is crucial to public ***,there exist challenges to the maintenance of the sterility of drinking water throughout the drinking water distribution systems（DWDS）.Microbial growth in DWDS,such as growth of opportunistic pathogenic microorganisms,can lead to severe health problems in consumers（Berry et al.,2006;Brettar and Hofle,2006;Lu et al.,2014;zh.ng et al.,2015）.

关键词： Drinking water distribution systems Microbial community High-throughput sequencing Water safety

Perspective on the relationship between microbiota dysbiosis and neuroinflammation:probiotics as a treatment option

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Neural Regeneration Research 2022年第9期17卷 1969-1970页

作者： Chiao W.ng Zahoor A.Shah Department of Medicinal and Biological Chemistry College of Pharmacy and Pharmaceutical SciencesUniversity of ToledoToledoOHUSA

Introduction:In the 1680s,Antonie van Leewenhoek was the first to observe the differences in the human gut microbiome versus the oral cavity diversity,and it led to the birth of a new term,“microbiota”.Later,the link between the brain and the gut was observed to be facilitated by the vagus nerve,allowing for neurotransmitters secreted in the gastrointestinal tract to travel to the brain,directing signals that influence brain *** gut microbiome is linked to various diseases ranging from autism spectrum disorder to Parkinson’s disease(PD)and is projected to be the new“disease-causing mechanism,”calling for interventions that can modulate gut microbiota and mitigate brain *** dysbiosis is observed before and after the onset of various neurodegenerative diseases and often manifests itself into gut-related diseases such as.

关键词： inflammation diseases treatment

Management of difficult intravenous access:a qualitative revie

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World Journal of Emergency Medicine 2022年第6期13卷 467-478页

作者： Mingwei ng Leong Kwok Fai Mark Lateef Fatimah Department of Emergency Medicine Singapore General HospitalSingapore 169608Singapore

BACKGROUND:A perennial challenge faced by clinicians and made even more relevant with the global obesity epidemic,difficult intravenous access(DIVA)adversely impacts patient outcomes by causing significant downstream delays with many aspects of diagnoses and *** most published DIVA strategies are limited to various point-of-care ultrasound techniques while other“tricks-of-the-trade”and pearls for overcoming DIVA are mostly relegated to informal nonpublished material,this article seeks to provide a narrative qualitative review of the iterature on DIVA and consolidate these strategies into a practical ***:We conducted a literature search on PubMed using the keywords“difficult intravenous access”,“peripheral vascular access”and“peripheral venous access”and searched emergency medicine and anaesthesiology resources for relevant *** strategies were then categorized and incorporated into a DIVA ***:We propose a Vortex approach to DIVA that is modelled after the Difficult Airway Vortex concept:starting off with standard peripheral intravenous cannulation(PIVC)techniques,progressing sequentially on to ultrasound-guided cannulation and central venous cannulation and finally escalating to the most invasive intraosseous access should the patient be in extremis or should best efforts with the other lifelines ***:DIVA is a perennial problem that healthcare providers across various disciplines will be increasingly challenged *** is crucial to have a systematic stepwise approach such as the DIVA Vortex when managing such patients and have at hand a wide repertoire of techniques to draw upon.

关键词： Difficult intravenous access Venepuncture Vortex Peripheral intravenous cannulation

Positron-Lithium Atom and Electron-Lithium Atom Scattering Systems at Intermediate and High Energies

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Chinese Physics Letters 2006年第7期23卷 1753-1756页

作者： K. Ratnavelu S. Y. ng Institute of Mathematical Sciences Faculty of Science University of Malaya 50603 Kuala Lumpur Malaysia Department of Physics Faculty of Science National University of Singapore Singapore

The coupled-channel optical method is used to study positron scattering by atomic lithium at energies ranging from the ionization threshold to 60eV, The present method simultaneously treats the target channels and the positronium （Ps） channels in the coupled-channel method together with the continuum effects via an ab-initio optical potential. Ionization, elastic and inelastic cross sections in target channels, and the total cross section are also reported and compared with other theoretical and experimental data. A comparative study with the corresponding electron-lithium data is also reported.

关键词： CLOSE-COUPLIng THEORY HYDROGEN SCATTERIng CROSS-SECTIONS COLLISIONS

Photoelectrochemical Behaviours of Tandem Semiconductive Electrode

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Chinese Chemical Letters 1997年第8期8卷 721-724页

作者： Jiang, DL Han, zh Song, YH Wang, QF Tong, RT Li, GC HEBEI TEACHERS UNIV DEPT CHEMHEBEI 050016PEOPLES R CHINA HEBEI CHEM EngN INST HEBEI 050016PEOPLES R CHINA

The photoelectrochemical behaviour of the multilayer semiconductive electrode(GaAs/AlxGa1-xAs)with the structure of N+NP and N+NPP was studied in Na2SO4 solution. Compared with single kind semiconductor electrode, the commposite one has broader photoresponse spectral region and larger open-circuit photovoltage,consequently gives higher solar energy conversion efficiency.

关键词： Ga Photoelectrochemical Behaviours of Tandem Semiconductive Electrode Li

Stability and Generalization of Hypergraph Collaborative Networks

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Machine Intelligence Research 2024年第1期21卷 184-196页

作者： Michael K.ng Hanrui Wu Andy Yip Institute of Data Science The University of Hong KongHong KongChina Department of Mathematics The University of Hong KongHong KongChina College of Information Science and Technology Jinan UniversityGuangzhou 510006China

Graph neural networks have been shown to be very effective in utilizing pairwise relationships across ***,there have been several successful proposals to generalize graph neural networks to hypergraph neural networks to exploit more com-plex *** particular,the hypergraph collaborative networks yield superior results compared to other hypergraph neural net-works for various semi-supervised learning *** collaborative network can provide high quality vertex embeddings and hyperedge embeddings together by formulating them as a joint optimization problem and by using their consistency in reconstructing the given *** this paper,we aim to establish the algorithmic stability of the core layer of the collaborative network and provide generaliz--ation *** analysis sheds light on the design of hypergraph filters in collaborative networks,for instance,how the data and hypergraph filters should be scaled to achieve uniform stability of the learning *** experimental results on real-world datasets are presented to illustrate the theory.

关键词： Hypergraphs vertices hyperedges collaborative networks graph convolutional neural networks(CNNs) stability generalization guarantees