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Reexamination of Criticality Accident in JCO

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Journal of Modern Physics 2016年第12期7卷 1500-1505页

作者： Sachiko Oshima Miri Hisada yusuke saito Takehisa Fujita College of Industrial Technology Nihon University Narashino Chiba Japan Department of Physics Faculty of Science and Technology Nihon University Tokyo Japan

Nuclear chain reactions are, by now, commonly used in the nuclear reactors, and thus it seems that there is no basic problem in fission processes from the scientific point of view. However, the criticality accident that occurred in JCO in 1999 suggests that one should carefully examine this accident from the nuclear physics point of view. Indeed the chain nuclear reactions should have taken place in the small area of space with 45 cm diameter disk times 30 cm height tank. In fact, when people carry the uranium nitrate solution into sedimentation tank, then this solution with uranium should get into the critical state at the 45? of uranium nitrate solution. The root cause of the accident should not be very simple from the nuclear physics point, and it should be quite important to examine why the uranium nitrate solution with 45? could have become critical.

关键词： Nuclear Fission Criticality Mean Free Path

Hyperacute experimental model of rat lung transplantation using a coronary shunt cannula

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World Journal of Transplantation 2024年第2期14卷 155-161页

作者： Munehisa Takata yusuke Tanaka Daisuke saito Shuhei Yoshida Isao Matsumoto Department of Thoracic Surgery Kanazawa UniversityKanazawa 920-8641IshikawaJapan

BACKGROUND Lung transplantation is a well-established treatment of end-stage lung disease.A rodent model is an inexpensive way to collect biological data from a living model after lung ***,mastering the surgical technique takes time owing to the small organ *** To conduct rat lung transplantation using a shunt cannula(SC)or modified cannula(MC)and assess their *** Rat lung transplantation was performed in 11 animals in the SC group and 12 in the MC *** devised a method of rat lung transplantation using a coronary SC for coronary artery bypass surgery as an anastomosis of pulmonary arteri-ovenous vessels and *** same surgeon performed all surgical proce-dures in the donor and recipient rats without using a magnifying *** success rate of lung transplantation,operating time,and PaO2 values were com-pared after 2-h reperfusion after *** Ten and 12 lungs were successfully transplanted in the SC and MC groups,*** the SC group,one animal had cardiac arrest within 1 h after reperfusion owing to bleeding during pulmonary vein *** opera-ting time for the removal of the heart-lung block from the donor and preparation of the left lung graft was 26.8±2.3 and 25.7±1.3 min in the SC and MC groups,respectively(P=0.21).The time required for left lung transplantation in the recipients was 37.5±2.8 min and 35.9±1.4 min in the SC and MC groups,respectively(P=0.12).PaO2 values at 2 h after reperfusion were 456.2±25.5 and INTRODUCTION Lung transplantation is a well-established treatment of end-stage lung *** immune and non-immune mech-anisms in lung transplantation are highly complex,and post-transplant complications such as infections and primary and chronic lung allograft dysfunction must be reduced to improve ***,there is a need for immunological and pathophysiological analyses using animal lung transplantation *** rat lung transplantation model was f

关键词： Lung transplantation Rat Shunt cannula Modified cannula Reperfusion

Measurement Method of Internal Residual Stress in Plastic Parts Using Terahertz Spectroscopy

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Nanomanufacturing and Metrology 2021年第1期4卷 46-52页

作者： yusuke Kajihara Rio Takahashi Ichiro Yoshida Shingo saito Norihiko Sekine Shuichi Nowatari Shigeo Miyake Institute of Industrial Science The University of TokyoKomaba 4-6-K Meguro-kuTokyoJapan Hosei University Kajino 3-7-2.KoganeiTokyoJapan National Institute of Information and Communications Technology Nukui-Kitamachi 4-2-1KoganeiTokyoJapan Iida Co. LtdNukazawa Mizukami 21-2MotomiyiaFukushimaJapan

Since internal residual stress in polymers causes dimension errors over time,a measurement method for residual stress in polymers,especially in opaque engineering plastics,is strongly *** this study,we propose to utilize terahertz(THz)spectroscopy to non-destructively measure internal residual stress in *** verify the validity of the proposed method,we manufactured polytetrafluoroethylene ring samples with and without residual stress,and studied them with THz time domain spectroscopy *** spectra of samples without residual stress showed almost no polarization difference,whereas spectra of samples with residual stress showed clear polarization *** changes between the samples with and without residual stress were also estimated and it was found that the change had a correlation with THz polarization *** experimental analyses confirm the validity for the proposed non-destructive measurement of residual stress in polymer.

关键词： Engineering plastics Residual stress Polarization Terahertz spectroscopy

Distribution of splenic artery lymph nodes and splenic hilar lymph nodes

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World Journal of Gastrointestinal Surgery 2023年第5期15卷 812-824页

作者： Yuya Umebayashi Satoru Muro Masanori Tokunaga Toshifumi saito Yuya Sato Toshiro Tanioka yusuke Kinugasa Keiichi Akita Department of Gastrointestinal Surgery Tokyo Medical and Dental UniversityTokyo 113-8519Japan Department of Clinical Anatomy Tokyo Medical and Dental UniversityTokyo 113-8519Japan

BACKGROUND Total gastrectomy with splenectomy is the standard treatment for advanced proximal gastric cancer with greater-curvature *** an alternative to splenectomy,laparoscopic spleen-preserving splenic hilar lymph node(LN)dissection(SPSHLD)has been *** SPSHLD,the posterior splenic hilar LNs are left *** To clarify the distribution of splenic hilar(No.10)and splenic artery(No.11p and 11d)LNs and to verify the possibility of omitting posterior LN dissection in laparoscopic SPSHLD from an anatomical *** Hematoxylin&eosin-stained specimens were prepared from six cadavers,and the distribution of LN No.10,11p,and 11d was *** addition,heatmaps were constructed and three-dimensional reconstructions were created to visualize the LN distribution for qualitative *** There was little difference in the number of No.10 LNs between the anterior and posterior *** LN No.11p and 11d,the anterior LNs were more numerous than the posterior LNs in all *** number of posterior LNs increased toward the hilar *** and three-dimensional reconstructions showed that LN No.11p was more abundant in the superficial area,while LN No.11d and 10 were more abundant in the deep intervascular *** The number of posterior LNs increased toward the hilum and was not ***,surgeons should consider that some posterior No.10 and No.11d LNs may remain after SPSHLD.

关键词： Gastric cancer Laparoscopic gastrectomy Anatomy Splenic hilar lymph node Laparoscopic spleen-preserving splenic hilar lymph node dissection

Histological study of the structural layers around the esophagus in the lower mediastinum

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World Journal of Gastrointestinal Surgery 2023年第7期15卷 1331-1339页

作者： Toshifumi saito Satoru Muro Hisashi Fujiwara Yuya Umebayashi Yuya Sato Masanori Tokunaga Keiichi Akita yusuke Kinugasa Department of Gastrointestinal Surgery Tokyo Medical and Dental UniversityBunkyo-ku 113-8519TokyoJapan Department of Clinical Anatomy Tokyo Medical and Dental UniversityBunkyo-ku 113-8519TokyoJapan

BACKGROUND In Japan,the transhiatal approach,including lower mediastinal lymph node dissection,is widely performed for Siewert type II esophagogastric junction *** procedure is generally performed in a magnified view using laparoscopy or a robotic system,therefore,the microanatomy of the lower mediastinum is ***,mediastinal microanatomy is still unclear and classification of lower mediastinal lymph nodes is not currently based on fascia or other microanatomical *** To clarify the fascia and layer structures of the lower mediastinum and classify the lower mediastinal *** We dissected the esophagus and surrounding organs en-bloc from seven cadavers fixed in 10%*** and tissues were then cut at the level of the lower thoracic esophagus,embedded in paraffin,and serially *** sections were stained with Hematoxylin-Eosin(all cadavers)and immunostained for the lymphatic endothelial marker D2-40(three cadavers).We observed the periesophageal fasciae and layers,and defined lymph node boundaries based on the *** vessels around the esophagus were observed on immunostained tissue *** We identified two fasciae,A and *** then classified lower mediastinal tissue into three areas,paraesophageal,paraaortic,and intermediate,using these fasciae as *** nodes were found to be present and were counted in each *** dorsal part of the intermediate area was thicker on the caudal side than on the cranial side in all *** the dorsal side,no blood vessels penetrated the fasciae in six of the seven cadavers,whereas the proper esophageal artery penetrated fascia B in one cadaver.D2-40 immunostaining showed lymphatic vessel connections between the paraesophageal and intermediate areas on the lateral and ventral sides of the esophagus,but no lymphatic connection between areas on the dorsal side of the *** Histological studies identified two fasciae surroun

关键词： Esophagogastric junction Histology Mediastinum Adenocarcinoma Esophageal cancer Gastric cancer

Hepatitis C virus enhances incidence of idiopathic pulmonary fibrosis

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World Journal of Gastroenterology 2008年第38期14卷 5880-5886页

作者： Yasuji Arase Fumitaka Suzuki Yoshiyuki Suzuki Norio Akuta Masahiro Kobayashi yusuke Kawamura Hiromi Yatsuji Hitomi Sezaki Tetsuya Hosaka Miharu Hirakawa Satoshi saito Kenji Ikeda Hiromitsu Kumada Department of Hepatology Toranomon HospitalTokyo 105-8470 Japan

AIM： To investigate the cumulative development incidence and predictive factors for idiopathic pulmonary fibrosis in hepatitis C virus （HCV） positive patients. METHODS： We studied 6150 HCV infected patients who were between 40-70 years old （HCV-group）. Another 2050 patients with hepatitis B virus （HBV） were selected as control （HBV-group）. The mean observation period was 8.0 ± 5.9 years in HCV-group and 6.3 ± 5.5 years in HBV-group. The primary goal is the development of idiopathic pulmonary fibrosis （IPF） in both groups. The cumulative appearance rate of IPF and independent factors associated with the incidence rate of IPF were calculated using the Kaplan- Meier method and the Cox proportional hazard model. All of the studies were performed retrospectively by collecting and analyzing data from the patient records in our hospital. RESULTS： Fifteen patients in HCV-group developed IPF. On the other hand, none of the patients developed IPF in HBV-group. In HCV-group, the cumulative rates of IPF development were 0.3% at 10th year and 0.9% at 20th year. The IPF development rate in HCV-group was higher than that in HBV-group （P = 0.021）. The IPF development rate in patients with HCV or HBV was high with statistical significance in the following cases：（1） patients ≥ 55 years （P 〈 0.001）; （2） patients who had smoking index （package per day x year） of ≥20 （P = 0.002）; （3） patients with liver cirrhosis （P = 0.042）. CONCLUSION： Our results indicate that age, smoking and liver cirrhosis enhance the development of IPF in HCV positive patients.

关键词： Hepatitis B virus Hepatitis C virus Idiopathic pulmonary fibrosis A retrospective cohort study

A Method for Structuring Service Failure Factors to Realize Highly Reliable Services

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Journal of Mechanics Engineering and Automation 2013年第12期3卷 747-755页

作者： Junpei saito yusuke Kurita Koji Kimita Yoshiki Shimomura Department of System Design Tokyo Metropolitan University Tokyo 19-0065 Japan Department of Management Science Tokyo University of Science Tokyo 162-8601 Japan

As the society matures, customer requirements have become more varied. Services have been attracting increasing attention from industry and academic field as an effective mean to satisfy such varied customer requirements. In order to make a profit, it is important for companies to build and maintain long-term relationships with customers. Therefore, service providers should maintain their service quality and always satisfy their customers. To realize highly reliable product or services, in general, it is an effective approach to prevent failures from occurring in the use phase. Therefore, it is necessary that analysts identify the factors that could cause service failure and take appropriate measures against the target failure factor in advance. However, service failure factors are varied compared to physical products because service failures occur due to uncertainty elements such as human factors. In this study, we aim to enable service analysts to identify the critical failure factor from a number of failure factors. To achieve this, we identify complex failure factors and relationships among them from the viewpoint of the field where the service provided. This paper proposes a method for structuring the causal sequence between service failure factors by using a method of system modeling.

关键词： Service failure factors service reliability service engineering.

Advantages of Ilizarov External Fixation in an Elderly Patient with Pilon Fracture with Severe Soft Tissue Injury and Severe Osteoporosis: A Case Report

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Open Journal of Orthopedics 2019年第1期9卷 14-22页

作者： Koji Nozaka Naohisa Miyakoshi Hidetomo saito Shuichi Chida Hiroyuki Tsuchie yusuke Yuasa Motoki Mita Yoichi Shimada Department of Orthopedic Surgery Akita University Graduate School of Medicine Hondo Akita Japan

Introduction: Pilon fracture in elderly individuals is characterized by senile skin atrophy, poor dermal extensibility, and thin subcutaneous tissue. The use of bulky internal fixation material can thus cause the swelling that accompanies the fracture to induce secondary injury to skin tissue. In addition, initiation of postoperative weight-bearing is delayed due to bone fragility and difficulties with partial weight-bearing, causing a tendency toward prolonged hospitalization. Mean duration of hospitalization after pilon fracture for elderly patients in our department was 79.2 days. Case Presentation: An 80-year-old woman with pilon fracture with soft tissue injury and severe osteoporosis was transferred to our department. The fracture was treated using Ilizarov external fixation. Fourteen days postoperatively, walking with full weight-bearing was permitted. The hospital stay was 28 days. The external fixator of the ankle was removed 87 days postoperatively, at which time the patient was anatomically and functionally recovered and able to walk unaided. Conclusion: Ilizarov external fixation may represent a useful option in elderly patients with pilon fracture showing severe soft tissue injury and severe osteoporosis. The present case provides evidence that this procdure can be successfully applied to the management of such pilon fractures in elderly patients.

关键词： Ilizarov External Fixation Elderly Patient Pilon Fracture Soft Tissue Injury Osteoporosis

Predictive model of risk factors of High Flow Nasal Cannula using machine learning in COVID-19

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Infectious Disease Modelling 2022年第3期7卷 526-534页

作者： Nobuaki Matsunaga Keisuke Kamata yusuke Asai Shinya Tsuzuki Yasuaki Sakamoto Shinpei Ijichi Takayuki Akiyama a Jiefu Yu Gen Yamada Mari Terada Setsuko Suzuki Kumiko Suzuki Sho saito Kayoko Hayakawa Norio Ohmagari AMR Clinical Reference Center National Center for Global Health and MedicineTokyoJapan DataRobot Inc. TokyoJapan Disease Control and Prevention Center National Center for Global Health and MedicineTokyoJapan Biostatistics Division Center for Research Administration and SupportNational Cancer CenterTokyoJapan

With the rapid increase in the number of COVID-19 patients in Japan,the number of patients receiving oxygen at home has also increased rapidly,and some of these patients have *** efficient approach to identify high-risk patients with slowly progressing and rapidly worsening COVID-19,and to avoid missing the timing of therapeutic intervention will improve patient prognosis and prevent medical *** admitted to medical institutions in Japan from November 14,2020 to April 11,2021 and registered in the COVID-19 Registry Japan were *** factors for patients with High Flow Nasal Cannula invasive respiratory management or higher were comprehensively explored using machine ***-specific cohorts were created,and severity prediction was performed for the patient surge *** were able to obtain a model that was able to predict severe disease with a sensitivity of 57%when the specificity was set at 90%for those aged 40e59 years,and with a specificity of 50%and 43%when the sensitivity was set at 90%for those aged 60e79 years and 80 years and older,*** were able to identify lactate dehydrogenase level(LDH)as an important factor in predicting the severity of illness in all age *** machine learning,we were able to identify risk factors with high accuracy,and predict the severity of the *** plan to develop a tool that will be useful in determining the indications for hospitalisation for patients undergoing home care and early hospitalisation.

关键词： COVID-19 Machine learning Severity Risk prediction Japan