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Endoscopic mucosal resection vs endoscopic submucosal dissection for superficial non-ampullary duodenal tumors

World Journal of Gastrointestinal Oncology 2020年第8期12卷 918-930页

作者： Mitsuru Esaki Kazuhiro Haraguchi Kazuya Akahoshi Naru Tomoeda Akira Aso Soichi Itaba Haruei Ogino yusuke kitagawa Hiroyuki Fujii Kazuhiko Nakamura Masaru Kubokawa Naohiko Harada Yosuke Minoda Sho Suzuki Eikichi Ihara Yoshihiro Ogawa Department of Medicine and Bioregulatory Science Graduate School of Medical SciencesKyushu UniversityFukuoka 8128582Japan Division of Gastroenterology and Hepatology Department of MedicineNihon University School of MedicineTokyo 1738610Japan Department of Gastroenterology Hara-Sanshin HospitalFukuoka 8120033Japan Department of Gastroenterology Aso Iizuka HospitalIizuka 8208502Japan Department of Gastroenterology Clinical Research InstituteNational Hospital Organization Kyushu Medical CenterFukuoka 8108564Japan Department of Gastroenterology Kitakyushu Municipal Medical CenterKitakyushu 8020077Japan Department of Gastroenterology Kyushu Rosai HospitalKitakyushu 8000296Japan Department of Internal Medicine Saiseikai Fukuoka General HospitalFukuoka 8100001Japan Department of Gastroenterology and Hepatology National Hospital Organization Fukuokahigashi Medical CenterKoga 81103195Japan Department of Gastroenterology and Metabolism Graduate School of Medicine SciencesKyushu UniversityFukuoka 8128582Japan

BACKGROUND The selection of endoscopic treatments for superficial non-ampullary duodenal epithelial tumors(SNADETs)is *** To compare the efficacy and safety of endoscopic mucosal resection(EMR)and endoscopic submucosal dissection(ESD)for *** We retrospectively analyzed the data of patients with SNADETs from a database of endoscopic treatment for SNADETs,which included eight hospitals in Fukuoka,Japan,between April 2001 and October 2017.A total of 142 patients with SNADETs treated with EMR or ESD were *** score matching was performed to adjust for the differences in the patient characteristics between the two *** analyzed the treatment outcomes,including the rates of en bloc/complete resection,procedure time,adverse event rate,hospital stay,and local or metastatic *** Twenty-eight pairs of patients were *** characteristics of patients between the two groups were similar after *** EMR group had a significantly shorter procedure time and hospital stay than those of the ESD group[median procedure time(interquartile range):6(3-10.75)min vs 87.5(68.5-136.5)min,P<0.001,hospital stay:8(6-10.75)d vs 11(8.25-14.75)d,P=0.006].Other outcomes were not significantly different between the two groups(en bloc resection rate:82.1%vs 92.9%,P=0.42;complete resection rate:71.4%vs 89.3%,P=0.18;and adverse event rate:3.6%vs 17.9%,P=0.19,local recurrence rate:3.6%vs 0%,P=1;metastatic recurrence rate:0%in both).Only one patient in the ESD group underwent emergency surgery owing to intraoperative *** EMR has significantly shorter procedure time and hospital stay than ESD,and provides acceptable curability and safety compared to ***,EMR for SNADETs is associated with lower medical costs.

关键词： Endoscopic mucosal resection Endoscopic submucosal dissection Superficial non-ampullary duodenal epithelial tumor Short-term Outcome Propensity score matching

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Assistant skill in gastric endoscopic submucosal dissection using a clutch cutter

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World Journal of Gastrointestinal Surgery 2021年第2期13卷 116-126页

作者： Mitsuru Esaki Toshiki Horii Ryoji Ichijima Masafumi Wada Seiichiro Sakisaka Shuichi Abe Naru Tomoeda yusuke kitagawa Kei Nishioka Yosuke Minoda Shinichi Tsuruta Sho Suzuki Hirotada Akiho Eikichi Ihara Yoshihiro Ogawa Takuji Gotoda Department of Medicine and Bioregulatory Science Graduate School of Medical SciencesKyushu UniversityFukuoka 812-8582Japan Division of Gastroenterology and Hepatology Department of MedicineNihon University School of MedicineTokyo 101-8309Japan Department of Gastroenterology Kitakyushu Municipal Medical CenterKitakyushu 802-0077FukuokaJapan Department of Internal Medicine Saiseikai Fukuoka General HospitalFukuoka 810-0001Japan Department of Gastroenterology Hara-Sanshin HospitalFukuoka 812-0033Japan Department of Gastroenterology Clinical Research InstituteNational Hospital Organization Kyushu Medical CenterFukuoka 810-0065Japan Department of Anatomic Pathology Kyushu UniversityFukuoka 812-8582Japan Department of Gastroenterology and Metabolism Graduate School of Medical SciencesKyushu UniversityFukuoka 812-8582Japan

BACKGROUND A clutch cutter is a scissor-type knife used in endoscopic submucosal dissection(ESD)for gastrointestinal tract *** assistant during the ESD using a clutch cutter(ESD-C)needs to rotate the device and grasp the target tissue appropriately;therefore,the assistant’s skill may affect the technical outcomes of *** To determine how assistant skill level affected the technical outcomes of gastric ESD-C using an ex vivo porcine training *** In this pilot study,mock lesions of 15-30 mm in diameter were created in the middle or lower third of the porcine stomach.A total of 32 ESD-C procedures were performed by 16 *** trainee operator performed two ESD-C procedures;one ESD-C was assisted by an expert(ESD-C-E),and the other was assisted by a non-expert(ESD-C-NE).The total procedure time of the ESD was set as the primary outcome,and en bloc resection rate,complete procedure rate,perforation rate,and each procedure time/speed for mucosal incision or submucosal dissection were set as the secondary *** addition,we investigated factors associated with the difficulty of ESD including incompletion of ESD procedure,a long procedure time(≥20 min)or intraoperative *** The median total procedure time of the ESD-C-E was significantly shorter than that of the ESD-C-NE(12.9 min vs 21.9 min,P=0.001).The en bloc resection rate was 100%in both *** resection rates of the ESD-C-E and ESD-C-NE groups were 100%and 93.8%,*** intraoperative perforation was observed in both *** the multivariate analysis,assistant skill was significantly associated with the difficulty of ESD,with the highest odds ratio of *** Assistance by an expert is an important factor when trainees perform ESD-C procedures.

关键词： Endoscopic submucosal dissection Porcine training model Clutch cutter Assistant Skill level

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Joint input–output identiﬁcation of unstable systems with kernel regularization

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Control Theory and Technology 2024年第2期22卷 195-202页

作者： yusuke Fujimoto Toshiharu Sugie Department of Environmental Engineering the University of Kitakyushu1-1HibikinoWakamatsu-kuKitakyushu 8080135FukuokaJapan Professor Emeritus Kyoto UniversityYoshida-HonmachiSakyo-kuKyoto 6068501KyotoJapan

This paper discusses closed-loop identiﬁcation of unstable *** particular,weﬁrst apply the joint input–output identiﬁcation method and then convert the identiﬁcation problem of unstable systems into that of stable systems,which can be tackled by using kernel-based regularization *** propose to identify two transfer functions by kernel regularization,the one from the reference signal to the input,and the one from the reference signal to the *** these transfer functions are stable,kernel regularization methods can construct their accurate *** the model of unstable system is constructed by ratio of these *** effectiveness of the proposed method is demonstrated by a numerical example and a practical experiment with a DC motor.

关键词： Closed-loop identification Kernel regularization Joint input-output identification

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Experimental aspects of ^(14)N overtone RESPDOR solid-state NMR spectroscopy under MAS beyond 60 kHz

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Magnetic Resonance Letters 2024年第1期4卷 40-49页

作者： Yutaro Ogaeri yusuke Nishiyama JEOL Ltd. AkishimaTokyo196-8558Japan

Nitrogen-14(^(14)N)overtone(OT)spectroscopy under fast magic angle spinning(MAS)conditions(>60 kHz)has emerged as a powerful technique for observing correlations and distances between ^(14)N and ^(1)H,owing to the absence of the first-order quadrupolar broad*** addition,^(14)N^(OT) allows selective manipulation of ^(14)N nuclei for each *** extensive theoretical and experimental studies,the spin dynamics of ^(14)N^(OT) remains under *** this study,we conducted experimental investigations to assess the spin dynamics of ^(14)N^(OT) using the rotational-echo saturation-pulse double-resonance(RESPDOR)sequence,which monitors population transfer induced by a^(14)N^(OT) *** ^(14)N^(OT) spin dynamics is well represented by a model of a two-energy-level *** spin-1/2,the maximum excitation efficiency of ^(14)N^(OT) coherences of powdered solids,denoted by p,depends on the radiofrequency field(rf-field)strength due to orientation dependence of effective nutation fields even when pulse lengths are *** is also found that the p factor,contributing to the ^(14)N^(OT) spin dynamics,is nearly independent of the B0 ***,the filtering efficiency of RESPDOR experiments exhibits negligible dependence on B0 when the ^(14)N^(OT) pulse length is *** study also identifies the optimal experimental conditions for ^(14)N^(OT)/^(1)H RESPDOR correlation experiments.

关键词： ^(14)N Overtone RESPDOR ^(14)N/^(1)H correlation Solid-state NMR Fast MAS

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Assessing efficacy of standard impregnation techniques on die-cast aluminum alloys using X-ray micro-CT

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China Foundry 2024年第3期21卷 276-286页

作者： Ajith Bandara Koichi Kan Katanaga yusuke Natsuto Soga Akifumi Koike Toru Aoki Hamamatsu TSC Chuo Hatsumei Institute322 lida-choMinami-kuHamamatsu435-0028Japan Graduate School of Medical Photonics ShizuokaUniversityJohoku 3-5-1HamamatsuShizuoka432-8561Japan ANSeeN Inc Johoku 3-5-1HamamatsuShizuoka432-8561Japan Research Institute of Electronics ShizuokaUniversityJohoku 3-5-1HamamatsuShizuoka432-8561Japan

Utilizing lightweight Al alloys in various industrial applications requires achieving precise pressure tightness and leak *** pressure impregnation(VPI)with thermosetting polymers is commonly used to address leakage defects in die-cast Al *** this study,the efficacy of the VPI technique in sealing alloy parts was investigated using a combination of nondestructive micro X-ray computed tomography(micro XCT)and a standard leak *** results demonstrate that the commonly used water leak test is insufficient for determining the sealing ***,micro XCT shows distinct advantages by enabling more comprehensive *** reveals the presence of a low atomic number impregnates sealant within casting defects,which has low grey contrast and allows for visualizing primary leakage paths in *** effective atomic number of impregnated resin is 6.75 and that of Al alloy is 13.69 by dual-energy X-ray *** research findings will contribute to enhancing the standard VPI process parameters and the properties of impregnating sealants to improve quality assurance for impregnation in industrial metals.

关键词： nondestructive testing Al alloy die-casting vacuum pressure impregnation micro X-ray computed tomography duel-energy X-ray CT

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Comment on:Recurrence after spontaneous separation of epiretinal membrane in a young woman:a case report

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International Journal of Ophthalmology(English edition) 2024年第4期17卷 783-784页

作者： yusuke Kameda Yutaka Kaneko Karin Ishinabe Nichika Fukuoka Yotsuya-sanchome Ekimae Eye Clinic Tokyo 160-0004Japan Department of Ophthalmology and Visual Sciences Yamagata University Faculty of MedicineYamagata 990-9585Japan

Dear Editor,Herein,we provide a commentary on the recently published article by Zeng QZ and Yu WZ[1].This case report provides interesting novel insights into the recurrence of epiretinal membrane(ERM)following self-separation in a young *** addition to the study,we have been investigating spontaneous ERM release for many years and have recently published a related paper[2].

关键词： separation young release

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Ethical decision-making in older drivers during critical driving situations: An online experiment

Journal of Intelligent and Connected Vehicles

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Journal of Intelligent and Connected Vehicles 2024年第1期7卷 30-37页

作者： Amandeep Singh Sarah Yahoodik Yovela Murzello Samuel Petkac yusuke Yamani Siby Samuel Department of Systems Design Engineering University of WaterlooWaterloo N2L 3G1Canada Department of Psychology Old Dominion UniversityNorfolk 23529USA

The present study examined the impact of aging on ethical decision-making in simulated critical driving scenarios.204 participants from North America,grouped into two age groups(18–30 years and 65 years and above),were asked to decide whether their simulated automated vehicle should stay in or change from the current lane in scenarios mimicking the Trolley *** participant viewed a video clip rendered by the driving simulator at Old Dominion University and pressed the space-bar if they decided to intervene in the control of the simulated automated vehicle in an online *** hierarchical models were used to analyze participants’responses,response time,and acceptability of utilitarian ethical *** results showed significant pedestrian placement,age,and time-to-collision(TTC)effects on participants’ethical *** pedestrians were in the right lane,participants were more likely to switch lanes,indicating a utilitarian approach prioritizing pedestrian *** participants were more likely to switch lanes in general compared to older *** results imply that older drivers can maintain their ability to respond to ethically fraught scenarios with their tendency to switch lanes more frequently than younger counterparts,even when the tasks interacting with an automated driving *** current findings may inform the development of decision algorithms for intelligent and connected vehicles by considering potential ethical dilemmas faced by human drivers across different age groups.

关键词： ethical decision making age-differences utilitarianism moral dilemmas driver behavior simulated driving bayesian hierarchical model

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应对热电材料人工智能领域的大数据挑战

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Science China Materials 2024年第4期67卷 1173-1182页

作者：贾雪 Alex Aziz yusuke Hashimoto 李昊 Advanced Institute for Materials Research(WPI-AIMR) Tohoku UniversitySendai 980-8577Japan Tohoku Forum for Creativity Tohoku UniversitySendai 980-8577Japan

人工智能的发展正在改变材料科学领域.然而,大规模材料数据集中存在错误数据以及利用机器学习预测与温度相关的性质时出现过拟合等挑战.本文以热电材料为例,首先采取一系列合理的方法删除问题数据,从Starrydata2数据库中获得包括7295种... 详细信息

人工智能的发展正在改变材料科学领域.然而,大规模材料数据集中存在错误数据以及利用机器学习预测与温度相关的性质时出现过拟合等挑战.本文以热电材料为例,首先采取一系列合理的方法删除问题数据,从Starrydata2数据库中获得包括7295种成分在不同温度下的92,291个数据.然后,提出了一种基于成分的交叉验证方法避免过拟合.进而,使用梯度提升决策树方法构建了机器学习模型,并获得了显著的R2.最后,使用该模型对Materials Project数据库中的材料进行评估,Ge2Te5As2和Ge3(Te3As)2表现出较高的zT值.理论计算得到n型和p型Ge2Te5As2的最大zT值为1.98和2.12,n型和p型Ge3(Te3As)2的最大zT值为0.58和0.74,表明它们是有潜力的热电材料.本工作提出了一个处理和克服材料科学中的人工智能大数据挑战的示例.

关键词：人工智能大数据机器学习过拟合热电材料材料数据数据库温度相关

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Hyperacute experimental model of rat lung transplantation using a coronary shunt cannula

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World Journal of Transplantation 2024年第2期14卷 155-161页

作者： Munehisa Takata yusuke Tanaka Daisuke Saito Shuhei Yoshida Isao Matsumoto Department of Thoracic Surgery Kanazawa UniversityKanazawa 920-8641IshikawaJapan

BACKGROUND Lung transplantation is a well-established treatment of end-stage lung disease.A rodent model is an inexpensive way to collect biological data from a living model after lung ***,mastering the surgical technique takes time owing to the small organ *** To conduct rat lung transplantation using a shunt cannula(SC)or modified cannula(MC)and assess their *** Rat lung transplantation was performed in 11 animals in the SC group and 12 in the MC *** devised a method of rat lung transplantation using a coronary SC for coronary artery bypass surgery as an anastomosis of pulmonary arteri-ovenous vessels and *** same surgeon performed all surgical proce-dures in the donor and recipient rats without using a magnifying *** success rate of lung transplantation,operating time,and PaO2 values were com-pared after 2-h reperfusion after *** Ten and 12 lungs were successfully transplanted in the SC and MC groups,*** the SC group,one animal had cardiac arrest within 1 h after reperfusion owing to bleeding during pulmonary vein *** opera-ting time for the removal of the heart-lung block from the donor and preparation of the left lung graft was 26.8±2.3 and 25.7±1.3 min in the SC and MC groups,respectively(P=0.21).The time required for left lung transplantation in the recipients was 37.5±2.8 min and 35.9±1.4 min in the SC and MC groups,respectively(P=0.12).PaO2 values at 2 h after reperfusion were 456.2±25.5 and INTRODUCTION Lung transplantation is a well-established treatment of end-stage lung *** immune and non-immune mech-anisms in lung transplantation are highly complex,and post-transplant complications such as infections and primary and chronic lung allograft dysfunction must be reduced to improve ***,there is a need for immunological and pathophysiological analyses using animal lung transplantation *** rat lung transplantation model was f

关键词： Lung transplantation Rat Shunt cannula Modified cannula Reperfusion

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A dynamic database of solid-state electrolyte(DDSE)picturing all-solid-state batteries

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Nano Materials Science 2024年第2期6卷 256-262页

作者： Fangling Yang Egon Campos dos Santos Xue Jia Ryuhei Sato Kazuaki Kisu yusuke Hashimoto Shin-ichi Orimo Hao Li Advanced Institute for Materials Research(WPI-AIMR) Tohoku UniversitySendai980-8577Japan Key Laboratory of Radiation Physics and Technology Ministry of EducationCollege of PhysicsSichuan UniversityChengdu610065People's Republic of China Institute for Materials Research(IMR) Tohoku UniversitySendai980-8577Japan Tohoku Forum for Creativity Tohoku UniversitySendai980-8577Japan

All-solid-state batteries(ASSBs)are a class of safer and higher-energy-density materials compared to conventional devices,from which solid-state electrolytes(SSEs)are their essential *** date,investigations to search for high ion-conducting solid-state electrolytes have attracted broad ***,obtaining SSEs with high ionic conductivity is challenging due to the complex structural information and the less-explored structure-performance *** provide a solution to these challenges,developing a database containing typical SSEs from available experimental reports would be a new avenue to understand the structureperformance relationships and find out new design guidelines for reasonable ***,a dynamic experimental database containing>600 materials was developed in a wide range of temperatures(132.40–1261.60 K),including mono-and divalent cations(e.g.,Li^(+),Na^(+),K^(+),Ag^(+),Ca^(2+),Mg^(2+),and Zn^(2+))and various types of anions(e.g.,halide,hydride,sulfide,and oxide).Data-mining was conducted to explore the relationships among different variates(e.g.,transport ion,composition,activation energy,and conductivity).Overall,we expect that this database can provide essential guidelines for the design and development of high-performance SSEs in ASSB *** database is dynamically updated,which can be accessed via our open-source online system.

关键词： Solid-state electrolyte(SSE) All-solid-state battery(ASSB) Ionic conductivity Dynamic database Machine learning

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