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Flow-restricted Etching Method on Isotropic Substrates and Its Mechanism

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Chinese Journal of Mechanical Engineering 2010年第5期23卷 560-567页

作者： XIE Haibo ZHENG Yi FAN yurun FU Xin yang Huayong The State Key Lab of Fluid Power Transmission and Control Zhejiang University Hangzhou 310027 China

With the development of analytical instrumentation to minimization,integration and automation,the microfluidic chips,which are more integrated,complex and diversified,have been applied widely on the manufacturing of analytical ***,the present photolithography-based microfabrication technology,which is only able to pattern microchannels with simple inside structures,can not follow the rapid development of *** solving the problem,a fabrication method based on the restricting effect of laminar flow is proposed for the micro etching on isotropic *** were conducted inside glass-based microchannels,in which certain etchant was used to form complicated *** flow parameters＇ effects on the aspect ratio,side wall profile and etching rate were revealed by the *** experimental results reveal that the topography of micro structures patterned with the restricted flow etching method is mainly determined by the flowrates of separator and *** computational fluid dynamics（CFD） model on the interface between multiple streams was established for the etching process,and analysis on the causes of various micro topographies was conducted based on the CFD simulation *** experimental data consisted with the simulation results very *** investigation depicted in this paper indicate that the flow restricted etching method provides sufficient references for the research and understanding on the mass transport at the liquid-liquid surface in the microchannel and can be used to pattern complex micro structures with high aspect ratios,meantime,it greatly enriches the microfabrication technology for microfluidic chips.

关键词： microfluidics etching computational fluid dynamics(CFD) laminar

Study on the effective elastic performance of composites containing decagonal symmetric two-dimensional quasicrystal coatings

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Applied Mathematics and Mechanics(English Edition) 2024年第9期45卷 1655-1664页

作者： yurun WU Lu LI Lianhe LI School of Mathematics and Science Inner Mongolia Normal UniversityHohhot 010022China Inner Mongolia Applied mathematics Center Hohhot 010022China Key Laboratory of Infinite Dimensional Hamiltonian System and Its Algorithm Application Ministry of EducationHohhot 010022China

On account of the Mori-Tanaka approach,the effective elastic performance of composites containing decagonal symmetric two-dimensional(2D)quasicrystal(QC)coatings is *** expressions for the effective elastic constants of rare-earth QC reinforced magnesium-based composites are *** discussion is presented on the effects of the volume fraction of the inclusions,the aspect ratio of the inclusions,the coating thickness,and the coating material parameters on the effective elastic constants of the *** results indicate that considering the coating increases the effective elastic constants of the composites to some extent.

关键词： Mori-Tanaka approach coated inclusion decagonal symmetric twodimensional(2D)quasicrystal(QC)

Gas Permeability and Free Volume Hole Properties of Interpenetrating Polymer Network Studied by Positrons

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Wuhan University Journal of Natural Sciences 2007年第2期12卷 271-274页

作者： QI Ning GONG Wei WANG Zhifen WANG Bo yang yurun HU Chunpu School of Physics and Technology Wuhan University Wuhan 430072 Hubei China Institute of Material Science and Engineering East China University of Science and Technology Shanghai 200237 China

A series of polyurethane/epoxy resin interpenetrating polymer networks （PU/ER IPN） were studied by positron annihilation lifetime spectroscopy （PALS）. The effects of epoxy resin type and content on the free volume properties in IPN were investigated. We found that in PU/ER IPN, the free volume hole size and fractional free volume showed a negative deviation due to closer segmental chain packing through some chemical bonding between PU and epoxy resin. Direct relationship between the gas permeability and the free volume has been established based on the free volume theory. Experimental results revealed that the free volume plays an important role in determining the gas diffusion and permeability.

关键词： interpenetrating polymer network positron annihilation free volume gas permeability

Infection-responsive long-term antibacterial bone plates for open fracture therapy

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Bioactive Materials 2023年第7期25卷 1-12页

作者： Lujiao Zhang yurun yang Yan-Hua Xiong Yu-Qing Zhao Zongpeng Xiu Hui-Min Ren Kai Zhang Shun Duan Ying Chen Fu-Jian Xu State Key Laboratory of Chemical Resource Engineering Key Lab of Biomedical Materials of Natural Macromolecules(Beijing University of Chemical Technology)Ministry of EducationBeijing Laboratory of Biomedical MaterialsBeijing Advanced Innovation Center for Soft Matter Science and EngineeringBeijing University of Chemical TechnologyBeijing100029China Department of Orthopaedic Surgery China-Japan Friendship HospitalBeijing100029China

The infections in open fracture induce high morbidity ***,developing efficient anti-infective orthopedic devices is of great *** this work,we designed a kind of infection-responsive long-term antibacterial bone *** a facile and flexible volatilization method,a multi-aldehyde polysaccharide derivative,oxidized sodium alginate,was crosslinked with multi-amino compounds,gentamycin and gelatin,to fabricate a uniform coating on Ti bone plates via Schiff base reaction,which was followed by a secondary crosslinking process by *** double-crosslinked coating was stable under normal condition,and could responsively release gentamycin by the triggering of the acidic microenvironment caused by bacterial metabolism,owning to the pH-responsiveness of imine *** thickness of the coating was ranging from 22.0μm to 63.6μ*** coated bone plates(Ti-GOGs)showed infection-triggered antibacterial properties(>99%)and high *** being soaked for five months,it still possessed efficient antibacterial ability,showing its sustainable antibacterial *** in vivo anti-infection ability was demonstrated by an animal model of infection after fracture fixation(IAFF).At the early stage of IAFF,Ti-GOGs could inhibit the bacterial infection(>99%).Subsequently,Ti-GOGs could promote recovery of fracture of *** work provides a convenient and universal strategy for fabrication of various antibacterial orthopedic devices,which is promising to prevent and treat IAFF.

关键词： Antibacterial Open fracture Infection-responsive Coating Orthopedic medical device

Macrophage exosomes modified by miR-365-2-5p promoted osteoblast osteogenic differentiation by targeting OLFML1

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Regenerative Biomaterials 2024年第3期3卷 134-147页

作者： Caiyao Hou Yujue Zhang Zhaoyong Lv yurun Luan Jun Li Chunxiu Meng Kun Liu Xin Luo Liyu Chen Fengzhen Liu Department of Materials Science and Engineering Liaocheng UniversityLiaocheng 252000China Liaocheng People's Hospital Liaocheng Hospital Affliated Shandong First Medical UniversityLiaocheng 252000China The Second Hospital Cheeloo College of MedicineShandong UniversityJinan 250023China

In the bone immune microenvironment,immune cells can regulate osteoblasts through a complex communication *** play a central role in mediating immune osteogenesis,exosomes derived from them have osteogenic regulation and can be used as cariers in bone tissue ***,there are problems with exosomal therapy alone,such as poor targeting,and the content of loaded molecules cannot reach the therapeutic *** this study,macrophage-derived exosomes modified with miR-365-2-5p were developed to accelerate bone ***3T3-E1 cells were incubated with the culture supermatants of Mo,M1 and M2 macrophages,and it was found that the culture medium of M2 macrophages had the most significant effects in contributing to ***-throughput sequencing identified that miR-365-2-5p was significantly expressed in exosomes derived from M2 *** incubated MC3T3-E1 with exosomes overexpressing or kmocking down miR-365-2-5p to examine the biological function of exosome miR-365-2-5p on MC3T3-E1 *** findings suggested that miR-365-2-5p secreted by exosomes increased the osteogenesis of ***,miR-365-2-5p had a direct influence over osteogenesis for *** analysis combined with dual luciferase detection indicated that miR-365-2-5p binded to the 3'-UTR of *** summary,exosomes secreted by M2 macrophages targeted OLFML1 through miR-365-2-5p to facilitate osteogenesis.

关键词： macrophage exosomes osteogenesis osteoimmunology

Vancouver B2型股骨假体周围骨折的诊断与治疗进展

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中华创伤骨科杂志 2018年第1期20卷 89-92页

作者：杨雨润陈瀛林朋北京中日友好医院创伤骨科 100029

人工髋关节置换术后股骨假体周围骨折的发生率日趋升高，目前广泛采用Vancouver分型指导临床，且对除Vancouver B2型以外的各型骨折的治疗原则已达成一定共识，但是对于Vancouver B2型股骨假体周围骨折的诊治仍存在一定争议。本文对Vanc... 详细信息

人工髋关节置换术后股骨假体周围骨折的发生率日趋升高，目前广泛采用Vancouver分型指导临床，且对除Vancouver B2型以外的各型骨折的治疗原则已达成一定共识，但是对于Vancouver B2型股骨假体周围骨折的诊治仍存在一定争议。本文对Vancouver B2型骨折的诊断要点和研究进展作一综述，旨在提高对该型骨折的认识。

关键词：假体周围骨折股骨骨折关节成形术置换髋诊断治疗

Reversible generation of dissipative Kerr solitons in a microresonator by the backward tuning method

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Chinese Optics Letters 2024年第7期22卷 53-58页

作者： Jihui Zheng Lingman Ni Wanghang Gu Linhua Jia yurun Zhai Qiong Niu Fumin Zhang Xinghua Qu Advanced Photonic Technology Laboratory College of Electronic and Optical Engineering&College of MicroelectronicsNanjing University of Posts and TelecommunicationsNanjing 210023China State Key Laboratory of Precision Measurement Technology and Instruments Tianjin UniversityTianjin 300072China

Soliton generation schemes have attracted considerable scholarly *** paper introduces a novel backward tuning method for the reversible generation of dissipative Kerr solitons(DKSs).Reversible soliton generation relies on the thermal stabilization of the auxiliary laser,coupled with backward tuning of the pump laser,significantly increasing the range of soliton steps by over 10 ***,the method alleviates the stringent auxiliary laser detuning *** adjusting the detuning of the auxiliary laser,diverse numbers of solitons can be deterministically generated,enhancing both flexibility and precision.

关键词： microresonator dissipative Kerr soliton reversible generation backward tuning

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星座卫星爆炸对空间碎片环境演化的影响分析

宇航学报 2024年第5期45卷 790-798页

作者：袁雨润杨科莹张景瑞李林澄北京理工大学宇航学院北京100081 北京航空航天大学宇航学院北京100191 南洋理工大学电气与电子工程学院新加坡639798

针对近年来巨型星座蓬勃发展和未来星座卫星爆炸解体对空间环境的隐患,构建了连续性方程与拓扑网络模型相结合的空间碎片环境演化模型,仿真分析了星座卫星爆炸与部署高度、卫星数量、任务后处置(PMD)时间的耦合作用对未来空间碎片环境... 详细信息

针对近年来巨型星座蓬勃发展和未来星座卫星爆炸解体对空间环境的隐患,构建了连续性方程与拓扑网络模型相结合的空间碎片环境演化模型,仿真分析了星座卫星爆炸与部署高度、卫星数量、任务后处置(PMD)时间的耦合作用对未来空间碎片环境的影响。结果表明,星座卫星爆炸会加剧空间环境的恶化,部署在1 200 km的1 440颗卫星星座,若卫星爆炸概率提升1%,总体空间物体数量将上升约18%,且在星座背景下,卫星任务后25年离轨处置的规则已无法满足空间环境可持续发展的需求。因此,减小星座卫星爆炸概率、发展高效的PMD策略对保障空间安全至关重要。

关键词：空间碎片演化模型星座卫星爆炸解体空间安全

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法官参与执行和解的实践逻辑及其限度

河南大学学报（社会科学版） 2024年第1期64卷 32-37,153页

作者：柴雨润浙江大学光华法学院浙江杭州310000

法官参与执行和解虽然被排除在现有规则之外,却成为司法实践中普遍存在的经验事实。这一现象的形成既可归因于执行难现状、司法政策调控以及法院考核要求等外因激励,也源自执行法官偏好纠纷解决、追求共同合作利益以及个人职业满足感等... 详细信息

法官参与执行和解虽然被排除在现有规则之外,却成为司法实践中普遍存在的经验事实。这一现象的形成既可归因于执行难现状、司法政策调控以及法院考核要求等外因激励,也源自执行法官偏好纠纷解决、追求共同合作利益以及个人职业满足感等内因驱动。法官的适度参与在客观上能够消除当事人的合意贫困化,找到当事人合作的突破口,最终促成和解方案的实现。然而过度的参与可能会带来“合意强制化”“调解曲解化”和“二次纠纷化”的风险,对此应坚持以当事人意思自治为中心的有限参与原则,将法官参与执行和解限定在释明和司法审查的范围内。

关键词：执行和解执行法官意思自治释明司法审查