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“Obese workshop”: Retrospective Study of the Advantages, Disease Preventions and weight losses

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Modern Plastic Surgery 2021年第3期11卷 49-56页

作者： José Humberto Cardoso Resende Murilo Calil Alves Aline Correia Barbosa Débora de Bortoli Verderio Nathália lima Sanchez Sabrina de Castro Silva Alexandre Jorge Rodrigues Anthony yuri Viana Pitanga Emídio Silva Falcã o Brasileiro[† ] UNIFAN Aparecida de Goiania Brasil

Obesity is termed as the pathology defined by excess body weight due to the increase in adipocytes. It can be visceral, close to the omentum, mesentery, and subcutaneous, accumulated in the hypodermis. It is a disease that entails metabolic, respiratory, locomotor, and cardiovascular problems, type II diabetes, cancer, and even mental problems. Established by the Body Mass Index (BMI) and defined from the relationship between weight (kg) and height (m) of individuals. In numerical terms, a person is considered obese when the BMI is equal to or greater than 30 kg/m. This retrospective study took into account the more than 30 years that the coordinator of this work has devoted to morbidly obese people and all his 47 years of experience in medicine. The first obese person of his career was 41 years old and weighed 210 kg. As soon as she arrived at the hospital, she said: “Doctor, I am here, because I need to enter a ‘workshop’, to repair my body”. From that moment on, the name “workshop” became part of a fantastic project with obese people called “Obese workshop”. Over time, the number of patients with this comorbidity has only increased, reaching, once, the point of speaking to 325 interested parties in a single day and in the same hall. In order to achieve satisfactory results, we have established a number of tests, by which we could diagnose several reasons that cause obesity. we selected randomly 20 patients of both sexes, morbidly obese, operated in 2013. we do not take into account age, race, creed, or social status.

关键词： Obesity Obese Arterial Hypertension Diabetes Bariatric Surgery weight loss Physical Exercises

Role of sex hormones in gastrointestinal motility in pregnant and non-pregnant rats

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world Journal of Gastroenterology 2016年第25期22卷 5761-5768页

作者： Juliana Fernandes Matos Madileine Francely Americo yuri Karen Sinzato Gustavo Tadeu Volpato luciana Aparecida Corá Marcos Felipe Freitas Calabresi Ricardo Brandt Oliveira debora Cristina Damasceno Jose Ricardo Arruda Miranda Sao Paulo State University BotucatuSP 18618-970Brazil Instituto de Ciencias Biologicas e da Saude Federal University of Mato GrossoBarra do GarcasMT 78600-000Brazil Universidade Estadual de Ciencias da Saude de Alagoas MaceioAL 57010-300Brazil Sao Paulo University Ribeirao PretoSP 14049-900Brazil

AIM: To correlate gastric contractility, gastrointestinal transit, and hormone levels in non-pregnant(estrous cycle) and pregnant rats using noninvasive techniques. METHODS: Female rats(n = 23) were randomly divided into(1) non-pregnant,(contractility, n =6; transit, n = 6); and(2) pregnant(contractility, n = 5; transit, n = 6). In each estrous cycle phase or at 0, 7, 14, and 20 d after the confirmation of pregnancy, gastrointestinal transit was recorded by AC biosusceptometry(ACB), and gastric contractility was recorded by ACB and electromyography. After each recording, blood samples were obtained for progesterone and estradiol determination. RESUlTS: In the estrous cycle, despite fluctuations of sex hormone levels, no significant changes in gastrointestinal motility were observed. Days 7 and 14 of pregnancy were characterized by significant changes in the frequency of contractions(3.90 ± 0.42 cpm and 3.60 ± 0.36 cpm vs 4.33 ± 0.25 cpm) and gastric emptying(168 ± 17 min and 165 ± 15 min vs 113 ± 15 min) compared with day 0. On these same days, progesterone levels significantly increased compared with control(54.23 ± 15.14 ng/m l and 129.96 ± 30.52 ng/ml vs 13.25 ± 6.31 ng/ml). On day 14, we observed the highest level of progesterone and the lowest level of estradiol compared with day 0(44.3 ± 15.18 pg/ml vs 24.96 ± 5.96 pg/ml). CONClUSION: Gastrointestinal motility was unaffected by the estrous cycle. In our data, high progesterone and low estradiol levels can be associated with decreased contraction frequency and slow gastric emptying.

关键词： Reproductive physiological process Sex hormones Gastrointestinal motility Magnetic fields Gastric emptying

皿蛛科光面双舟蛛雄性新发现(蜘蛛目,皿蛛科)(英文)

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动物分类学报 2006年第2期31卷 330-334页

作者：宋妍婧李枢强 yuri M. MARUSIK 中国科学院动物研究所北京100080 俄罗斯科学院北方生物问题研究所马加丹68500

首次报道了雄性光面双舟蛛Dicymbiumfacetum(*** ,1879) ,并对其形态结构进行了详细描述。研究标本采自俄罗斯马加丹。

关键词：皿蛛科微蛛亚科双舟蛛属雄性新发现

Preparation of Fluoroalkyl End-Capped Oligomer/Cyclodextrin Polymer Composites: development of Fluorinated Composite Material Having a Higher Adsorption Ability toward Organic Molecules

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Journal of Encapsulation and Adsorption Sciences 2018年第2期8卷 117-138页

作者： Jun-Ichi Suzuki Yutaro Takegahara yuri Oikawa Yuta Aomi Hideo Sawada department of Frontier Materials Chemistry Graduate School of Science and Technology Hirosaki University Hirosaki Japan Kankyo Kogaku Hirosaki Japan

Fluoroalkyl end-capped vinyltrimethoxysilane oligomer [RF-(CH2CHSi(OMe)3)n-RF;RF = CF(CF3)OCF7, n = 2, 3;RF-(VM)n-RF] was applied to the preparation of fluoroalkyl end-capped vinyltrimethoxysilane oligomer/α-, β-, γ-cyclodextrin polymers (α-, β-, γ-CDPs) composites [RF-(VM-SiO2)n-RF/α-, β-, γ-CDPs] by the sol-gel reaction of the corresponding oligomer in the presence of the α-, β-, γ-CDPs under alkaline conditions. The RF-(VM-SiO2)n-RF/α-, β-, γ-CDPs composites thus obtained were found to give a good dispersibility toward the traditional organic media except for water, and were applied to the surface modification of glass to provide a sueperoleophilic/superhydrophobic characteristic on the modified surface, although the corresponding RF-(VM-SiO2)n-RF nanocomposites can give a usual oleophobic/superhydrophobic property on the surface. These composites powders were also found to be applicable to the packing material for the column chromatography to separate the mixture of oil/water and the water in oil (w/O) emulsions. More interestingly, these composite powders were found to have a higher adsorption ability toward not only low-molecular weight aromatic compounds such as bisphenol A and bisphenol AF but also volatile organic compounds, compared to that of the pristine α-, β-, γ-CDPs.

关键词： Fluorinated Oligomeric Composite Cyclodextrin Polymer Surface Modification Superoleophilic Superhydrophobic Property Separation of Oil and water Organic Molecule VOC Adsorption Ability

利用探针跳跃式扫描离子电导显微镜技术揭示结直肠癌单细胞层面对H_(2)O_(2)良性应激的动态响应

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Science Bulletin 2024年第12期69卷 1909-1919页

作者：王东 Emily woodcock 杨羲 Hiromi Nishikawa Elena V.Sviderskaya Masanobu Oshima Christopher Edwards 张彦军 yuri Korchev wPI Nano life Science Institute(wPI-Nano lSI) Kanazawa UniversityKanazawa 920-1192Japan department of Medicine Imperial College LondonLondon W120NNUnited Kingdom Cell Biology Research Centre Molecular and Clinical Sciences Research InstituteSt George’sUniversity of LondonLondon SW170REUnited Kingdom

Colorectal cancer(CRC),a widespread malignancy,is closely associated with tumor microenvironmental hydrogen peroxide(H_(2)O_(2))*** clinical trials targeting H_(2)O_(2)for cancer treatment have revealed its paradoxical role as a promoter of cancer *** the dynamics of cancer cell H_(2)O_(2)eustress at the single–cell level is *** this study,non–contact hopping probe mode scanning ion conductance microscopy(HPICM)with high-sensitive Pt–functionalized nanoelectrodes was employed to measure dynamic extracellular to intracellular H_(2)O_(2)gradients in individual colorectal cancer Caco–*** explored the relationship between cellular mechanical properties and H_(2)O_(2)*** to 0.1 or 1 mmol/l H_(2)O_(2)eustress increased the extracellular to intracellular H_(2)O_(2)gradient from 0.3 to 1.91 or 3.04,***,cellular F–actin–dependent stiffness increased at 0.1 mmol/l but decreased at 1 mmol/l H_(2)O_(2)*** H_(2)O_(2)–induced stiffness modulated AKT activation positively and glutathione peroxidase 2(GPX2)expression *** findings unveil the failure of some H_(2)O_(2)-targeted therapies due to their ineffectiveness in generating H_(2)O_(2),which instead acts eustress to promote cancer cell *** research also reveals the complex interplay between physical properties and biochemical signaling in cancer cells'antioxidant defense,illuminating the exploitation of H_(2)O_(2)eustress for survival at the single–cell *** GPX and/or catalase(CAT)enhances the cytotoxic activity of H_(2)O_(2)eustress against CRC cells,which holds significant promise for developing innovative therapies targeting cancer and other H_(2)O_(2)-related inflammatory diseases.

关键词： SPM Nanoprobe Nanobiology SECM ROS Stiffness

Historical land Use/Cover Changes and the Hemeroby levels of a Bio-Cultural landscape: Past, Present and Future

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Journal of Geographic Information System 2017年第5期9卷 576-590页

作者： Angela Terumi Fushita José Eduardo dos Santos yuri Tavares Rocha Elisabete Maria Zanin Center of Engineering Modeling and Applied Social Sciences Universidade Federal do ABC (UFABC) Santo André Brazil Pos-Graduate Programme in Ecology and Natural Resources Universidade Federal de S&#227 o Carlos (UFSCar) S&#227 o Carlos Brazil department of Geography Universidade de S&#227 o Paulo (USP) S&#227 o Paulo Brazil department of Biological Science Universidade Regional Integrada do Alto Uruguai e das Miss&#245 es (URI) Erechim Brazil

The urbanization of a campus landscape has required much space for this expansion, reinforcing the status of geographical space as a limited resource. we analyzed the effects of land cover change assessed over temporal dataset on composition and configuration dynamics of UFSCar (Federal University of São Carlos) campus landscape, based on a descriptive view of the hemeroby levels, over a 54-year period (1962-2016), in order to understand the impacts of past anthropogenic induced landscape change and inform decision making with regard to biodiversity management. The classification of land use/cover dynamics, over time, was obtained based on screen digitizing of aerial photos and landSat imagery. An ordinal scale ranging from ahemerob to metahemerob was applied to assess the hemerobiotic state of each land use type. Currently, The UFSCar landscape campus configures a biocultural mosaic in different stages of hemeroby. Thus a campus landscape dynamics model, which can be denoted as “forestry-conservation-urban model”, anthropogenic landscape is replaced by natural one, later by land cover reflecting the spatial anthropization process. Through time, two hemerobiotic trajectories were identified, in which 1) an euhemerob landscape matrix is substituted by an ahemerob one, resulting in increased naturalness of the campus landscape, and then 2) metahemerob patch types will later on increasing as a consequence of ongoing urbanization. Expressive amount of ahemerob patches in campus landscape fulfills one of the conditions for maintenance of the capacity for self-regulation and sustainability of a biocultural landscape. This framework provides an essential tool supporting with essential information about current and historical landscape sustainability for campus landscape management and support decision making process. The main institutional challenge for campus landscape sustainable management lies in the balance between the competitors of the campus landscape matrix:

关键词： land Use Change Trajectories Urbanization Conservation landscape Sustainable Management

Recent advances on study of hadrosaurid dinosaurs in Heilongjiang(Amur) River area between China and Russia

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Global Geology 2011年第3期14卷 160-191页

作者： Pascal Godefroit Pascaline lauters Jimmy Van Itterbeeck yuri l. Bolotsky DONG Zhiming JIN liyong wU wenhao Ivan Y. Bolotsky HAI Shulin YU Tingxiang Royal Belgian Institute of Natural Sciences Department of Palaeontology B -I 000 Bruxelles Belgium Afdeling Historische Geologie Katholieke Universiteit Leuven B -3000 Leuven Belgium Amur Natural History Museum Institute of Geology and Nature Exploration FEB RAS 675000 BlagoveschenskAmurskaya Oblast＇ Russia IVPP Beijing 100044 / Research Center of Paleontology and Stratigraphy Jilin University Changchun 130026 China Museum of Jilin University Changchun 130026 China Research Center for Paleontology and Stratigraphy Jilin University Changchun 130061 China The Geological Museum of Heilongjiang Harbin 150036 China

Four main dinosaur-bearing sites have been investigated in latest Cretaceous deposits from the Amur/Heilongjiang Region ： Jiayin and wulaga in China （ Yuliangze Formation）, Blagoveschensk and Kundur in Russia （Udurchukan Formation）. More than 90% of the bones discovered in these localities belong to hollow-crested lambeosaurine hadrosaurids： Charonosaurus fiayinensis at Jiayin, Amurosaurus riabinini at Blagoveschensk, Olorotitan arharensis at Kundur, and Sahaliyania elunchunorum at wulaga. Flat-headed hadrosaurine hadrosaurids are much less numerous, but appear well diversified as well： Kerberosaurus manakini at Blagoveschensk, wulagasaurus dongi at wulaga, and a new genus at Kundur. Theropods are represented by shed teeth and isolated bones; isolated scutes and teeth discovered at Kundur are tentatively attributed to nodosaurids. Palynological studies suggest that these sites are probably synchronous with the lancian＇ vertebrate localities of western North America, which represent the youngest dinosaur faunas in this area. However, the latest Cretaceous dinosaur assemblages are completely different in the Amur/Heilongjiang region （lambeosaurines abundant, ceratopsids absent） and in western North America （ceratopsids abundant, lainbeosaurines extremely rare or absent）. This probably reflects some kind of geographical barrier between both areas by Maastrichtian time rather than strong differences in palaeoecological conditions.

关键词： Heilongjiang Province Amur Region late Cretaceous dinosaurs Hadrosauridae palaeobiogeography

Growth of Micropropagated Solanum tuberosum *** under Artificial Solar Spectrum and Different Mono-and Polychromatic lED lights

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Horticultural Plant Journal 2022年第2期8卷 205-214页

作者： Olga V.Grishchenko Eugeny P.Subbotin Irina V.Gafitskaya Yulia V.Vereshchagina Elena V.Burkovskaya Yulia A.Khrolenko Valeria P.Grigorchuk Olga V.Nakonechnaya Victor P.Bulgakov yuri N.Kulchin Federal Scientific Center of the East Asia Terrestrial Biodiversity Far Eastern Branch of the Russian Academy of SciencesVladivostok 690022Russia Institute of Automation and Control Processes Far Eastern Branch of the Russian Academy of SciencesVladivostok 690041Russia

In agriculture,lED light sources have increasingly replaced the standard luminescent lamps and have acquired an important role in plant *** studied the effect of different light sources such as narrow-band lEDs(bright blue,blue,green,yellow,deep red,and red)and wide-band lEDs(cold white,white,warm white,full spectrum,and an artificial solar spectrum sun box constructed by us)on development of potato plantlets in *** luminescent lamps were used as a *** light intensity of 49μmol·m^(-2)·s^(-1)was provided in all light *** showed that the long-wave narrow-band light treatments were inapplicable for potato micropropagation,because plantlets were weak with small leaves,inhibited roots,and significantly elongated *** lights provided growth of shortened plantlets with large leaves,well-growing roots,and abundant green *** chlorophyll content was lower under blue and bright blue light and was at the same level in the remained *** differences in the stomatal apparatus development were observed depending on the light *** differences were not always reflected in the plantlet phenotype:e.g.,plantlets under blue and bright blue lights showed no differences in any characteristics except stomatal density and size of stomatal guard *** found no significant effect of blue light portion in the white lights and full spectrum on plantlet *** artificial solar spectrum sun box was the most suitable for potato micropropagation,because it supported the development of plantlets with good fitness,uniform internodes length,abundant roots and green mass accumulation.

关键词： Solanum tuberosum lED Artificial solar light Growth Micropropagation

利用Picarro测试石笋包裹体水氢、氧同位素的方法

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科学通报 2020年第32期65卷 3626-3634页

作者：田野张海伟宗保云段鹏珍 Hubert B.Vonhof yuri V.Dublyansky 宁有丰 Christoph Spotl 蔡演军程海西安交通大学全球环境变化研究院西安710054 department of Climate Geochemistry Max Planck Institute for ChemistryMainz 55128Germany Institute of Geology University of InnsbruckInnsbruck 6020Austria

基于当前石笋包裹体水提取测试过程中面临的制约条件,本研究设计了用于提取石笋包裹体水的真空装置,将其与水同位素分析仪Picarro l2140-i相连接组成石笋包裹体水氢、氧同位素(δD、δ18O)测试系统.该系统能够快速地提取石笋包裹体中的... 详细信息

基于当前石笋包裹体水提取测试过程中面临的制约条件,本研究设计了用于提取石笋包裹体水的真空装置,将其与水同位素分析仪Picarro l2140-i相连接组成石笋包裹体水氢、氧同位素(δD、δ18O)测试系统.该系统能够快速地提取石笋包裹体中的水,并对其δD和δ18O的值进行测量.包裹体水真空提取装置使用了以高压气缸为驱动的破碎研磨器,具有良好的破碎效果;在120°C真空条件下破碎获得的包裹体水随后被高纯氮气带入到Picarro l2140-i中进行测量分析.为了验证包裹体水测试系统的可靠性和准确性,本研究分别将石笋包裹体水真空提取装置以及Picarro液态水自动进样器与Picarro l2140-i主机连接,对相同的水样品进行了对比测试.两种方法测得的δ18O和δD值在误差范围内接近.使用该系统对东亚季风区石笋样品进行的测试结果显示:石笋包裹体水的δ18O和δD值分布在全球大气降水线附近,表明测试过程中分馏作用较小;包裹体含水量对测试精度有一定影响,对于水汽浓度为2500~50000 ppm(1 ppm=1μl/l)的样品,δ18O、δD的标准差分别为0.5‰、2‰,与同类型系统相当.研究结果表明该系统能如实测量石笋包裹体水的δ18O和δD值,将为利用水-碳酸钙平衡分馏方程重建古温度提供重要的技术支撑.

关键词：石笋包裹体稳定同位素水同位素分析仪(Picarro) 波长扫描光腔衰荡光谱古温度