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Intracellular and Extracellular Phosphatidylinositol 3-Phosphate Produced by Phytophthora Species Is Important for Infection

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Molecular Plant 2013年第5期6卷 1592-1604页

作者： Shan Lu Linlin Chen Kai Tao Nannan Sun yuren wu Xiaoxue Lu Yuanchao Wang Daolong Dou Department of Plant Pathology Nanjing Agricultural University Nanjing 210095 China Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education) Nanjing 210095 China

RxLR effectors produced by Phytophthora pathogens have been proposed to bind to phosphatidylinositol 3-phosphate （Ptdlns（3）P） to mediate their translocation into host cells and/or to increase their stability in planta. Since the levels of Ptdlns（3）P in plants are low, we examined whether Phytophthora species may produce Ptdlns（3）P to pro- mote infection. We observed that Ptdlns（3）P-specific GFP biosensors could bind to P. parasitica and P. sojae hyphae dur- ing infection of Nicotiana benthamiana leaves transiently secreting the biosensors, suggesting that the hyphae exposed Ptdlns（3）P on their plasma membrane and/or secreted Ptdlns（3）R Silencing of the phosphatidylinositol 3-kinases （PI3K） genes, treatment with LY294002, or expression of Ptdlns（3）pobinding proteins by P. sojae reduced the virulence of the pathogen on soybean, indicating that pathogen-synthesized Ptdlns（3）P was required for full virulence. Secretion of Ptdlns（3）P-binding proteins or of a PI3P-5-kinase by N. benthamiana leaves significantly increased the level of resist- ance to infection by P. parasitica and P. capsici. Together, our results support the hypothesis that Phytophthora species produce external Ptdlns（3）P to aid in infection, such as to promote entry of RxLR effectors into host cells. Our results derived from P. sojae RxLR effector Avrlb confirm that both the N-terminus and the C-terminus of this effector can bind Ptdlns（3）P.

关键词： Phytophthora sojae RxLR effectors phosphatidylinositol 3-phosphate (Ptdlns(3)P) phosphatidylinositol3-kinases (PI3Ks).

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钢轨全尺寸可靠性疲劳试验方法

铁道学报 1983年第4期 94-100页

作者：程育仁吴鸿遥北方交通大学北京工业大学

为了将可靠性原理应用于轨道的强度分析,首先必须测定钢轨疲劳极限的随机分布,本文提出用升降法来完成这一任务。由于升降法提供了具有存活率指标的疲劳极限值,可以为评定钢轨的质量提供新的指标。本文建议用95％存活率的疲劳极限来代... 详细信息

为了将可靠性原理应用于轨道的强度分析,首先必须测定钢轨疲劳极限的随机分布,本文提出用升降法来完成这一任务。由于升降法提供了具有存活率指标的疲劳极限值,可以为评定钢轨的质量提供新的指标。本文建议用95％存活率的疲劳极限来代替平均疲劳极限(50％左右存活率)作为钢轨的疲劳极限。

关键词：疲劳极限分布规律随机分布持久极限疲劳力学性质对数正态分布钢轨升降法应力水平疲劳寿命钢轨疲劳疲劳试验方法分散性全尺寸

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大学物理网上自学试点的实践与思考

物理与工程 2001年第1期11卷 38-42,58页

作者：刘海兰吴於人顾牡同济大学物理系上海200092

《大学物理》网上自学试点 (限正规在校生 )是教育部资源委员会向全国推广远程教育的重大举措之一 .本文通过回顾一学期网上自学试点的教学过程 ,总结了第一手资料 ,提出了一些有待探讨的问题。

关键词：网上自学学生主体性网络教学资源《大学物理》高校远程教育物理教学

国家治理现代化视角下环境会计的发展与创新研究

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内蒙古科技与经济 2024年第8期 67-70页

作者：王昱人吴琳瑕吉首大学商学院湖南吉首416000

文章基于国家治理现代化宏观背景,分析了在国家治理现代化步伐中应用环境会计的必要性,并针对环境会计发展暴露出的问题提出了相应的建议,为会计向新领域的变革和发展提供参考,以规范企业社会责任,强化企业环保意识,推动环境会计的发展... 详细信息

文章基于国家治理现代化宏观背景,分析了在国家治理现代化步伐中应用环境会计的必要性,并针对环境会计发展暴露出的问题提出了相应的建议,为会计向新领域的变革和发展提供参考,以规范企业社会责任,强化企业环保意识,推动环境会计的发展与创新。

关键词：国家治理现代化环境会计改革创新

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混沌的演示教学法

物理与工程 2001年第4期11卷 25-27页

作者：陆汝杰吴於人刘海兰同济大学物理系上海200092

混沌现象存在于绝大多数非线性系统中 .物理教学有必要引入混沌 .在高校工科物理混沌教学中我们利用三类混沌演示实验 ,进行了多种媒体的演示教学设计 ,激发学生探索未知世界的兴趣 ,使学生在学习混沌理论的同时学习思考问题、解决问题... 详细信息

混沌现象存在于绝大多数非线性系统中 .物理教学有必要引入混沌 .在高校工科物理混沌教学中我们利用三类混沌演示实验 ,进行了多种媒体的演示教学设计 ,激发学生探索未知世界的兴趣 ,使学生在学习混沌理论的同时学习思考问题、解决问题的方法 .

关键词：混沌非线性物理教学演示教学高校

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多核集成支持向量机合成孔径雷达目标分类

指挥信息系统与技术 2022年第3期13卷 36-43页

作者：周一鸣吴玉仁沈项军朱倩吴蔚张江涛江苏大学计算机科学与通信工程学院江苏镇江212013 信息系统工程重点实验室南京210023 中国电子科技集团公司第二十八研究所南京210023

雷达数据的复杂性增加了合成孔径雷达(SAR)目标分类和识别的难度。传统的多核分类方法先在单个再生核希尔伯特空间(RKHS)中学习基核的线性组合,再通过学习相关参数对SAR目标进行分类。由于传统方法忽略了多核中的最佳参数选择以及多核... 详细信息

雷达数据的复杂性增加了合成孔径雷达(SAR)目标分类和识别的难度。传统的多核分类方法先在单个再生核希尔伯特空间(RKHS)中学习基核的线性组合,再通过学习相关参数对SAR目标进行分类。由于传统方法忽略了多核中的最佳参数选择以及多核之间的结构特征,因此会导致识别结果出现偏差。鉴于此,提出了一种多核集成支持向量机SAR目标分类方法,通过设计一个集成损失函数将多个单独的核分类损失进行集成,从而将多个单独的核分类模型统一成一个整体,并共同优化和学习多个单独模型的最优参数。试验结果表明,该方法与SimpleMKL和SpicyM⁃KL等方法相比,在移动与静止目标搜索与识别(MSTAR)计划的多类别SAR数据集上的分类识别准确率可提升0.5%~10%。

关键词：合成孔径雷达多核学习集成损失共享参数

踏踏实实创建现代探究型大学物理精品课程体系

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物理与工程 2005年第6期15卷 22-25页

作者：吴於人于明章鲍鸿吉顾牡毛骏健同济大学物理系上海200092

本文介绍了同济大学如何构建探究型学习环境,创建全面提升学生素质的学习模式,设计能培养优秀人才的教学内容;研究科学的评价体系;创建现代探究型大学物理精品课程体系.

关键词：探究型大学物理环境模式评价

Engineering Fe‑N_(4)Electronic Structure with Adjacent Co‑N_(2)C_(2)and Co Nanoclusters on Carbon Nanotubes for Efficient Oxygen Electrocatalysis

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纳微快报:英文版 2023年第12期15卷 283-297页

作者： Mingjie wu Xiaohua Yang Xun Cui Ning Chen Lei Du Mohamed Cherif Fu‑Kuo Chiang yuren Wen Amir Hassanpour Francois Vidal Sasha Omanovic Yingkui Yang Shuhui Sun Gaixia Zhang State Key Laboratory of New Textile Materials and Advanced Processing Technologies Wuhan Textile UniversityWuhan 430200People’s Republic of China Institut National de la Recherche Scientifique(INRS) Center Energie Materiaux TelecommunicationsVarennesQC J3X 1P7Canada Department of Chemical Engineering McGill University3610 University StreetMontrealQC H3A 0C5Canada Department of Electrical Engineering Ecole de Technologie Superieure(ETS)MontrealQC H3C 1K3Canada Canadian Light Source(CLS) 44 Innovation BoulevardSaskatoonSK S7N 2V3Canada National Institute of Low-Carbon-and-Clean-Energy Beijing 102211People’s Republic of China School of Materials Science and Engineering University of Science and Technology BeijingBeijing 100083People’s Republic of China

Regulating the local configuration of atomically dispersed transition-metal atom catalysts is the key to oxygen electrocatalysis performance *** the previously reported singleatom or dual-atom configurations,we designed a new type of binary-atom catalyst,through engineering Fe-N_(4)electronic structure with adjacent Co-N_(2)C_(2)and nitrogen-coordinated Co nanoclusters,as oxygen *** resultant optimized electronic structure of the Fe-N_(4)active center favors the binding capability of intermediates and enhances oxygen reduction reaction(ORR)activity in both alkaline and acid *** addition,anchoring M-N-C atomic sites on highly graphitized carbon supports guarantees of efficient charge-and mass-transports,and escorts the high bifunctional catalytic activity of the entire ***,through the combination of electrochemical studies and in-situ X-ray absorption spectroscopy analyses,the ORR degradation mechanisms under highly oxidative conditions during oxygen evolution reaction processes were *** work developed a new binary-atom catalyst and systematically investigates the effect of highly oxidative environments on ORR electrochemical *** demonstrates the strategy for facilitating oxygen electrocatalytic activity and stability of the atomically dispersed M-N-C catalysts.

关键词： Atomically dispersed Fe-N-C catalysts ORR/OER Rechargeable zinc-air battery Fuel cells

Comparison of simple discectomy and instrumented posterior lumbar interbody fusion for treatment of lumbar disc herniation combined with Modic endplate changes

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Chinese Medical Journal 2014年第15期127卷 2789-2794页

作者： Cao Peng Chen Zhe Zheng Yuehuan Wang yuren Jiang Leisheng Yang Yaoqi Zhuang Chengyu Liang Yu Zheng Tao Gong Yaocheng Zhang Xingkai wu Wenjian Qiu Shijing Department of Orthopaedics Ruijin Hospital School of Medicine Jiao Tong University and Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases with Integrated Chinese- Western Medicine Shanghai Institute of Traumatology and Orthopaedics Shanghai 200025 China Shanghai Institute of Traumatology and Orthopaedics Shanghai200025 China Department of Orthopaedics Xinhua Hospital School of MedicineJiao Tong University Shanghai 200092 China

Background The purpose of this retrospective study was to compare the surgical outcomes of simple discectomy and instrumented posterior lumbar interbody fusion （iPLIF） in patients with lumbar disc herniation and Modic endplate *** hypothesis was that iPLIF could provide better outcome for patients with refractory lumbar disc herniation and Modic changes （LDH-MC）.Methods Ninety-one patients with single-segment LDH-MC were *** patients experienced low back pain as well as radicular leg pain,and low back pain was more severe than leg ***-seven patients were treated with discectomy and 44 were treated with iPLIE The outcomes of both low back pain and radicular leg pain using visual analogue scale （VAS） as well as the clinical outcome related to low back pain using Japanese Orthopaedic Association （JOA） score were assessed before and 18 months after surgery,*** Both low back and leg pain were significantly improved 18 months after simple discectomy and iPLIE Compared to patients undergoing simple discectomy,low back pain was significantly reduced in patients undergoing iPLIE but there was no significant difference in leg pain between two *** fusion was achieved in all patients who underwent *** In patients with LDH-MC,iPLIF can yield significantly superior outcome on the relief of low back pain compared to simple *** discectomy can relieve radicular leg pain as efficient as iPLIE Accordingly,iPLIF seems to be a reliable treatment for patients with LDH-MC and predominant low back pain.

关键词： lumbar disc herniation modic changes discectomy, instrumented posterior lumbar interbody fusion low back pain